• Title/Summary/Keyword: mace

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The Extent of Late Gadolinium Enhancement Can Predict Adverse Cardiac Outcomes in Patients with Non-Ischemic Cardiomyopathy with Reduced Left Ventricular Ejection Fraction: A Prospective Observational Study

  • Eun Kyoung Kim;Ga Yeon Lee;Shin Yi Jang;Sung-A Chang;Sung Mok Kim;Sung-Ji Park;Jin-Oh Choi;Seung Woo Park;Yeon Hyeon Choe;Sang-Chol Lee;Jae K. Oh
    • Korean Journal of Radiology
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    • v.22 no.3
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    • pp.324-333
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    • 2021
  • Objective: The clinical course of an individual patient with heart failure is unpredictable with left ventricle ejection fraction (LVEF) only. We aimed to evaluate the prognostic value of cardiac magnetic resonance (CMR)-derived myocardial fibrosis extent and to determine the cutoff value for event-free survival in patients with non-ischemic cardiomyopathy (NICM) who had severely reduced LVEF. Materials and Methods: Our prospective cohort study included 78 NICM patients with significantly reduced LV systolic function (LVEF < 35%). CMR images were analyzed for the presence and extent of late gadolinium enhancement (LGE). The primary outcome was major adverse cardiac events (MACEs), defined as a composite of cardiac death, heart transplantation, implantable cardioverter-defibrillator discharge for major arrhythmia, and hospitalization for congestive heart failure within 5 years after enrollment. Results: A total of 80.8% (n = 63) of enrolled patients had LGE, with the median LVEF of 25.4% (19.8-32.4%). The extent of myocardial scarring was significantly higher in patients who experienced MACE than in those without any cardiac events (22.0 [5.5-46.1] %LV vs. 6.7 [0-17.1] %LV, respectively, p = 0.008). During follow-up, 51.4% of patients with LGE ≥ 12.0 %LV experienced MACE, along with 20.9% of those with LGE ≤ 12.0 %LV (log-rank p = 0.001). According to multivariate analysis, LGE extent more than 12.0 %LV was independently associated with MACE (adjusted hazard ratio, 6.71; 95% confidence interval, 2.54-17.74; p < 0.001). Conclusion: In NICM patients with significantly reduced LV systolic function, the extent of LGE is a strong predictor for long-term adverse cardiac outcomes. Event-free survival was well discriminated with an LGE cutoff value of 12.0 %LV in these patients.

농촌부부의 배우자역할 평가 및 향상 프로그램 개발 연구

  • 양순미
    • Proceedings of the Korean Society of Community Living Science Conference
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    • 2004.05a
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    • pp.126-133
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    • 2004
  • 우리사회에 이혼률이 급증하고(조이혼률 : 1990년 1.1건$\longrightarrow$2002년 3.0건), 가족생활주기중에 학령기 부부의 결혼만족이 가장 낮다는 연구결과들(서동인ㆍ정현숙, 1994 등)이 제기되면서 어느 때보다 가족관계 또는 부부관계의 질적인 향상에 관한 관심이 증가하고 있다. 실제로 Mace (1979)등은 가족향상에서 가장 중요한 것은 부부중심(couple-focused)이며 행동중심(action- oriented)이라고 하였다.

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농촌부부의 배우자역할 평가 및 향상 프로그램 개발 연구

  • 양순미
    • Proceedings of the Korean Society of Community Living Science Conference
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    • 2004.05a
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    • pp.247-252
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    • 2004
  • 우리사회에 이혼률이 급증하고(조이혼률 : 1990년 1.1건$\longrightarrow$2002년 3.0건), 가족생활주기 중에 학령기 부부의 결혼만족이 가장 낮다는 연구결과들(서동인ㆍ정현숙, 1994등)이 제기되면서 어느 때보다 가족관계 또는 부부관계의 질적인 향상에 관한 관심이 증가하고 있다. 실제로 Mace(1979) 등은 가족향상에서 가장 중요한 것은 부부중심(couple-focused)이며 해동중심(action-oriented)이라고 하였다. 더 나가가 부부관계를 평가함에 있어서는 자기역할보다는 배우자역할 평가가 중요하다고 보고 (최규련, 1988; 서광희, 1992)되고 있다.

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Determination of Aqnifer Characteristics from Specific Capacity Data of Wells in Cheju Island (제주도 지하수의 우물 비양수량자료를 이용한 대수층상수 결정방법)

  • 최병수
    • Journal of the Korean Society of Groundwater Environment
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    • v.6 no.4
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    • pp.180-187
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    • 1999
  • Transmissivity is often estimated from specific capacity data because of the expense of conducting standard aquifer test to obtain transmissivity and the relative availability of specific capacity data. Most often, analytic expression relating specific capacity to transmissivity derived by Theis (1963). Brown (1963). and Logan (1964) are used in this analysis. The analytic solution typically used to predict transmissivity from specific capacity in alluvial aquifers assuming influence radius and/or storage coefficient of the aquifers. But those do not agree well with the measured transmissivity in fractured rock aquifers and in heterogeneous aquifers. Razack-Huntely (199l). Huntely-Steffey (1992). and Mace (1997) proposed emphirical rotations between specific capacity and transmissivity in heterogeneous alluvial aquifers. fractured rock aquifers, and karst aquifers. This study focuses on comparison between transmissivity and specific capacity data in volcanic rock aquifers of Jeju Island. Emphirical relation between the log of transmissivity and the log of specific capacity suggests they no linearly related (correlation coefficient 0.951) and the width of $\pm$0.25 log cycles in transmissivity includes 96.6% of data.

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Clinical outcomes and characteristics of acute myocardial infarction patients with developing fever after percutaneous coronary intervention

  • Jae-Geun Lee;Yeekyoung Ko;Joon Hyouk Choi;Jeong Rae Yoo;Misun Kim;Ki Yung Boo;Jong Wook Beom;Song-Yi Kim;Seung-Jae Joo
    • Journal of Medicine and Life Science
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    • v.19 no.2
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    • pp.46-56
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    • 2022
  • The incidence of fever complicating percutaneous coronary intervention (PCI) is rare. However, little is known regarding the cause of fever after PCI. Therefore, this study aimed to determine the clinical characteristics of patients with acute myocardial infarction (AMI), with or without fever, after PCI. We enrolled a total of 926 AMI patients who underwent PCI. Body temperature (BT) was measured every 4 hours or 8 hours for 5 days after PCI. Patients were divided into two groups according to BT as follows: BT<37.7℃ (no-fever group) and BT ≥37.7℃ (fever group). The 2 years clinical outcomes were compared subsequently. Fever after PCI was associated with higher incidence of major adverse cardiac events (MACE) (hazard ratio [HR], 1.56; 95% confidence interval [CI], 1.07-2.28; P=0.021), all-cause death (HR, 2.32; 95% CI, 1.18-4.45; P=0.014), cardiac death (CD) (HR, 2.57; 95% CI, 1.02-6.76; P=0.049), and any revascularization (HR, 1.69; 95% CI, 1.02-2.81; P=0.044) than without fever. In women, prior chronic kidney disease, lower left ventricular (LV) ejection fraction, higher LV wall motion score index, white blood cell count, peak creatine kinase-myocardial band level, and longer PCI duration were associated with fever after PCI. Procedures such as an intra-aortic balloon pump, extracorporeal membrane oxygenation, continuous renal replacement therapy, central and arterial line insertion, and cardiopulmonary resuscitation were related to fever after PCI. Fever after PCI in patients with AMI was associated with a higher incidence of MACE, all-cause death, CD, and any revascularization at the 2 years mark than in those without fever.

Approximation of Multiple Trait Effective Daughter Contribution by Dairy Proven Bulls for MACE (젖소 국제유전능력 평가를 위한 종모우별 다형질 Effective Daughter Contribution 추정)

  • Cho, Kwang-Hyun;Choi, Tae-Jeong;Cho, Chung-Il;Park, Kyung-Do;Do, Kyoung-Tag;Oh, Jae-Don;Lee, Hak-Kyo;Kong, Hong-Sik;Lee, Joon-Ho
    • Journal of Animal Science and Technology
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    • v.55 no.5
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    • pp.399-403
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    • 2013
  • This study was conducted to investigate the basic concept of multiple trait effective daughter contribution (MTEDC) for dairy cattle sires and calculate effective daughter contribution (EDC) by applying a five lactation multiple trait model using milk yield test records of daughters for the Multiple-trait Across Country Evaluation (MACE). Milk yield data and pedigree information of 301,551 cows that were the progeny of 2,046 Korean and imported dairy bulls were collected from the National Agricultural Cooperative Federation and used in this study. For MTEDC approximation, the reliability of the breeding value was separated based on parents average, own yield deviation and mate adjusted progeny contribution. EDC was then calculated by lactation using these reliabilities. The average number of recorded daughters per sire by lactations were 140.57, 94.24, 55.14, 29.20 and 14.06 from the first to fifth lactation, respectively. However, the average EDC per sire by lactation using the five lactation multiple trait model was 113.49, 89.28, 73.56, 54.02 and 35.08 from the first to fifth lactation, respectively, while the decrease of EDC in late lactations was comparably lower than the average number of recorded daughters per sire. These findings indicate that the availability of daughters without late lactation records is increased by genetic correlation using the multiple trait model. Owing to the relatedness between the EDC and reliability of the estimated breeding value for sire, understanding the MTEDC algorithm and continuous monitoring of EDC is required for correct MACE application of the five lactation multiple trait model.

Multiplexed Optical Correlation Filter for Optical Parallel Addition Based on Symbolic Substitution with Redundant Binary Number (기호치환을 기초로 한 잉여 이진수 광병렬 가산용 다중 광상관 필터)

  • 노덕수;조웅호;김정우;이하운;김수중
    • Journal of the Korean Institute of Telematics and Electronics B
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    • v.33B no.3
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    • pp.109-119
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    • 1996
  • We propsoed a multiplexed optical correlation filter method for an optical parallel addition based on symbolic substitution. In the proposed mthod, we used redundant binary number which was easy to minimize the number of the symbolic substitution rules. We chose MACE filter which had very low sidelobes and good correlation peak compared with SDF filter as the optical correlation recognition filter and encoded input numbers properly to increase the discrimination capability. In order to minimize the number of symbolic substitution rules, sixteen input patterns were divided into six groups of the same addition results and six filters for recognizing the input patterns were used. these filters were multiplexed in two MMACE filter planes and the corresponding substitution method was proposed. Through the computer simulation, we confirmed the proposed method was suitable to implement the optical parallel adder.

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Load and Capacitor Stacking Topologies for DC-DC Step Down Conversion

  • Mace, Jules;Noh, Gwangyol;Jeon, Yongjin;Ha, Jung-Ik
    • Journal of Power Electronics
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    • v.19 no.6
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    • pp.1449-1457
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    • 2019
  • This paper presents two voltage domain stacking topologies for powering integrated digital loads such as multiprocessors or 3D integrated circuits. Pairs of loads and capacitors are connected in series to form a stack of voltage domains. The voltage is balanced by switching the position of the capacitors in one case and the position of the loads in the other case. This method makes the voltage regulation robust to large differential load power consumption. The first configuration can be named the load stacking topology. The second configuration can be named the capacitor stacking topology. This paper aims at proposing and comparing these two topologies. Models of both topologies and a switching scheme are presented. The behavior, control scheme, losses and overall performance are analyzed and compared theoretically in simulation and experiments. Experimental results show that the capacitor stacking topology has better performance with a 30% voltage ripple reduction.

Digital Forensic Analysis of Timestamp Change Tools: An Anti-Forensics Perspective (안티포렌식을 위한 타임스탬프 변경도구들에 대한 디지털포렌식 관점에서의 기능의 분석)

  • Cho, Gyu-Sang
    • Proceedings of the Korean Society of Computer Information Conference
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    • 2019.07a
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    • pp.391-392
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    • 2019
  • 본 논문에서는 타임스탬프의 위변조를 위한 안티포렌식의 도구로 사용되는 타임스탬프 변경도구들에 기능에 대하여 디지털 포렌식 관점에서 분석을 수행한다. 타임스탬프 변경도구들로써 수행할 수 있는 타임스탬프 변경작업의 범위와 특징을 찾아본다. NTFS파일시스템에서 사용하는 타임스탬프 변경도구들의 기능상의 분류는 그것들이 변경할 수 있는 타임스탬프 종류와 정밀도를 기준으로 정하고 그 도구들을 사용한 후에 기록된 타임스탬프의 특징들을 디지털 포렌식 관점에서 분석을 수행하기로 한다. 이 연구에서의 분류 형태 중 타입 I은 FileTouch.exe, SKTimeStamp, BulkFileChanger류의 도구들과 타입 II는 timestomp, 타입 III은 SetMACE로 분류하고 각 도구들을 사용한 후에 변경된 타임스탬프들의 특징을 살펴보기로 한다.

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ROLES OF HUMAN LIVER CYTOCHROMES P450 3A4 AND 1A2 IN THE OXIDATION OF MYRISTICIN

  • Yun, Chul-Ho;Lee, Hye-Suk;Lee, Hee-Yong;Yim, Sung-Kun;Kim, Keon-Hee;Yea, Sung-Su
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.137.1-137.1
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    • 2003
  • Myristicin, 1-allyl-3, 4-methylenedioxy-5-methoxybenzene, is a naturally occurring alkenylbenzene compound. It is found in nutmag, mace, parsley, carrot, black pepper, many natural oils and flavoring agents. The aim of this work was to identify the form(s) of human liver cytochrome P450 (P450) involved in the hepatic transformation of myristicin to its major metabolite, 5-allyl-1-methoxy-2, 3-dihydroxybenzene (M1). (omitted)

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