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New Cosmetic Agents for Anti-aging from Zostera marina L. (잘피(Zostera marina L.)의 신규 항노화 화장품 소재 응용)

  • Jin-Hui, Kim;Kyung-Eun, Lee;Jin-Hwa, Kim;Young-Ho, Cho;Sung-Min, Park;Jeong-Jae, Lee;Bum-Chun, Lee;Hyeong-Bae, Pyo
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.30 no.2
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    • pp.235-240
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    • 2004
  • In order to develop new anti-photoaging agents from marine natural products, Zostera marina L. was selected for its antioxidative activity and inhibition of matrix metalloproteinase-1 (MMP-1) expression. Three compounds (compounds 1, 2, and 3) were isolated from the extract, and they were identified as apigenin-7-O-${\beta}$-D-glucoside (1), chrysoeriol (2), and luteolin (3). These compounds have SC$\_$50/ values of 0.18 mM, 0.68 mM, and 0.01 mM against l,l-dipheny1-2-picrylhydrazyl radical and 0.04mM, 0.03mM, and 0.01mM against the superoxide radical in the xanthine/xanthine oxidase system, respectively. Compound 3 suppressed the expression of MMP-1 by up to 44% at 35.0${\mu}$M and inhibited the production of interleukin 6, which is known as a cytokine that induces MMP-1 expression. In addition, the wrinkle improvement effect of the formulation with Z. marina extract was measured. As a result, remarkable reduction was found in the fine wrinkle and skin roughness after application of the cream with 3.0% this extract for 8 weeks. In conclusion, the isolated compounds from Z. marina extract were good antioxidant and suppressor of MMP-1 expression and the formulation with the extract diminished the skin wrinkle. Therefore, the extract can be used as a new anti-aging agent for application in cosmetic.

The Vegetation Characteristics of the Upper Area of Timber Line in Mt. Paektu (백두산 수목한게량 상부의 식생특성)

  • 길봉섭;유현경;김영식;김창환
    • The Korean Journal of Ecology
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    • v.21 no.5_2
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    • pp.519-529
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    • 1998
  • The vegetation of alpine and subalpine zone from timber line, 2,000m altitude, to the upper area of Mt. Packtu were investigated by phytosociological method. The plant distribution along to the different altitudes shown as follows: Betula ermani community with Rhododendron redowskianum occupied dominantly at 2,000m area as patch forms, Rhododendron redowskianum community with Vaccinium uliginosum, at 2,180-2,200m area, both Vaccinium uliginosum and Rhododendron redowskianum community were compatible with each other at 2,243m area. Rhododendron redowskianum community at 2,250, Salix rotundifolia community, Erigeron thunbergii var. glabrata community, Dryas octopetala var. asiatica community and Carex atrata community were occurred frequently at 2,263m around Chonji Lake. Rhododendron aureum, Thunbergii coccinea and V accinium uliginosum showed higher cover degree than other species at 2,370m area, Phyllodoce coerulea-Rhododendron aureum community at 2,400m, Rhododendron redowskianum community at 2,470m, Rhododendron aureum community at 2,490m, Salix rotundifolia at 2,520m, Rhododendron redowskianum community at 2,580m, Dryas octopetala var. asiatica community, Salix rotundifolia, and bistorta achotensis etc. at 2,650 altitude area were settled as sparse, creeping shape on the surface soil and dwarf plants of about 15cm heights.

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Relationship Between CFRP Ply Orientation and Performance Stroke in Piezoelectric Zirconate Titanate Composite Actuator(PZTCA) of Artificial Muscle (인공근육에 적용되는 압전복합재료 작동기의 탄소섬유 배향각과 작동변위의 관계)

  • Kim Cheol-Woong;Lee Sung-Hyuk;Yoon Kwang-Joon
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2005.10a
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    • pp.641-644
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    • 2005
  • The aim of this research is to evaluate the relationship between the total effective moment $(M^E)$ and Bemoulli-Euler bending moment (M) when the ply orientations of UD CFRP in Piezoelectric Zirconate Titanate Composite Actuator (PZTCA) are changed. The obtained results as follows. Firstly, as the performance test results by the CFRP ply orientation, the performance of [0] and [90] were stable. However, while the performance of [+45] was suddenly decreased after 5 hours. Secondly, the change of $M^E$ by the CFRP ply orientation was evaluated. As the CFRP ply orientation was increased from [0] to [+60], the $M^E$ were gradually decreased. However, they became a little bit increased from [+60] to [90]. Finally, after the change of M by the CFRP ply orientation was evaluated, it was found that $M^E=2.2M$ was valid for just [0] and that there was a relationship between $M^E$ and M according to the ply orientation.

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Anatomical Observation on Components Related to Foot Gworeum Meridian Muscle in Human

  • Park, Kyoung-Sik
    • The Journal of Korean Medicine
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    • v.32 no.3
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    • pp.1-9
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    • 2011
  • Objectives: This study was carried out to observe the foot gworeum meridian muscle from a viewpoint of human anatomy on the assumption that the meridian muscle system is basically matched to the meridian vessel system as a part of the meridian system, and further to support the accurate application of acupuncture in clinical practice. Methods: Meridian points corresponding to the foot gworeum meridian muscle at the body surface were labeled with latex, being based on Korean standard acupuncture point locations. In order to expose components related to the foot gworeum meridian muscle, the cadaver was then dissected, being respectively divided into superficial, middle, and deep layers while entering more deeply. Results: Anatomical components related to the foot gworeum meridian muscle in human are composed of muscles, fascia, ligament, nerves, etc. The anatomical components of the foot gworeum meridian muscle in cadaver are as follows: 1. Muscle: Dorsal pedis fascia, crural fascia, flexor digitorum (digit.) longus muscle (m.), soleus m., sartorius m., adductor longus m., and external abdominal oblique m. aponeurosis at the superficial layer, dorsal interosseous m. tendon (tend.), extensor (ext.) hallucis brevis m. tend., ext. hallucis longus m. tend., tibialis anterior m. tend., flexor digit. longus m., and internal abdominal oblique m. at the middle layer, and finally posterior tibialis m., gracilis m. tend., semitendinosus m. tend., semimembranosus m. tend., gastrocnemius m., adductor magnus m. tend., vastus medialis m., adductor brevis m., and intercostal m. at the deep layer. 2. Nerve: Dorsal digital branch (br.) of the deep peroneal nerve (n.), dorsal br. of the proper plantar digital n., medial br. of the deep peroneal n., saphenous n., infrapatellar br. of the saphenous n., cutaneous (cut.) br. of the obturator n., femoral br. of the genitofemoral n., anterior (ant.) cut. br. of the femoral n., ant. cut. br. of the iliohypogastric n., lateral cut. br. of the intercostal n. (T11), and lateral cut. br. of the intercostal n. (T6) at the superficial layer, saphenous n., ant. division of the obturator n., post. division of the obturator n., obturator n., ant. cut. br. of the intercostal n. (T11), and ant. cut. br. of the intercostal n. (T6) at the middle layer, and finally tibialis n. and articular br. of tibial n. at the deep layer. Conclusion: The meridian muscle system seemed to be closely matched to the meridian vessel system as a part of the meridian system. This study shows comparative differences from established studies on anatomical components related to the foot gworeum meridian muscle, and also from the methodical aspect of the analytic process. In addition, the human foot gworeum meridian muscle is composed of the proper muscles, and also may include the relevant nerves, but it is as questionable as ever, and we can guess that there are somewhat conceptual differences between terms (that is, nerves which control muscles in the foot gworeum meridian muscle and those which pass nearby) in human anatomy.

A Study of Changes in the Primary Dose Penetrating the Protective Apron on SID in X-ray Radiography (X선촬영에서 보호앞치마를 투과한 1차 선량의 SID별 변화)

  • Choi, Seong-Kwan
    • Journal of radiological science and technology
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    • v.39 no.4
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    • pp.501-507
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    • 2016
  • This study is to figure out the amount of primary X-ray generated in SID 50cm, 1m, and 2m penetrating protective aprons in X-ray radiography for hands, skull, and lumbar spine. Results are as follows: Firstly, the exposure dose of primary X-ray which is low such as that of hand X-ray may be reduced by 270 times if protective aprons are worn, but it still slightly penetrates 0.3mm thick Pb protective aprons at SID 50cm, 1m, and 2m. Secondly, the exposure dose of primary X-ray which is moderate such as that of skull X-ray may be reduced by 22 times if protective aprons are worn, but it still fairly penetrates 0.3mm thick Pb protective aprons at SID 50cm, 1m, and 2m. Thirdly, the exposure dose of primary X-ray which is very high such as that of lumbar spine X-ray may be reduced by 13 times if protective aprons are worn, but it still penetrates a lot 0.3mm thick Pb protective aprons at SID 50cm, 1m, and 2m. Therefore, people in X-ray room should not only wear protective aprons at any spaces that the primary X-ray can reach, but also need to stand behind the thick Pb shield to protect the body if it is inevitable to stay in the room.

A Performance Analysis on the Traffic Control of OSI Network Management Protocol (OSI망 관리 프로토콜의 트래픽 제어에 대한 성능 분석)

  • 변옥환;진용옥
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.17 no.7
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    • pp.758-766
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    • 1992
  • In this paper, the traffic control scheme used by M-cancel-Get services In CMIS /CMIP, OSI network management protocol, is presented and the performance is analyzed. M -Get service which allows a multiple response functional unit is a service that searches an attribute of the managed sys-tem and the service requires a large quantity of response as its typical characteristics. At the time, management response is transmitted Irrelevant to the network condition In the managed as well as In the management system. The management system requests M Canrel-Get service which informs the canrelation of M -Get service (or Information retrieval. In case of using M-Cancel-Get service for traffic control, the point of time for traffic control is propose by the result of simulation on management response time as the number of multiple response packets is Increased. The result is analyzed by processing ratio of the network workload and the average delay time of packets. As a result, the traffic control parameters proposed in the study show superiority in its processing ratio and the average packet delay time. Especially, its performance improves as the size of background traffic density Increase.

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BOUNDED MOVEMENT OF GROUP ACTIONS

  • Kim, Pan-Soo
    • Communications of Mathematical Education
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    • v.5
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    • pp.523-523
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    • 1997
  • Suppose that G is a group of permutations of a set ${\Omega}$. For a finite subset ${\gamma}$of${\Omega}$, the movement of ${\gamma}$ under the action of G is defined as move(${\gamma}$):=$max\limits_{g{\epsilon}G}|{\Gamma}^{g}{\backslash}{\Gamma}|$, and ${\gamma}$ will be said to have restricted movement if move(${\gamma}$)<|${\gamma}$|. Moreover if, for an infinite subset ${\gamma}$of${\Omega}$, the sets|{\Gamma}^{g}{\backslash}{\Gamma}| are finite and bounded as g runs over all elements of G, then we may define move(${\gamma}$)in the same way as for finite subsets. If move(${\gamma}$)${\leq}$m for all ${\gamma}$${\subseteq}$${\Omega}$, then G is said to have bounded movement and the movement of G move(G) is defined as the maximum of move(${\gamma}$) over all subsets ${\gamma}$ of ${\Omega}$. Having bounded movement is a very strong restriction on a group, but it is natural to ask just which permutation groups have bounded movement m. If move(G)=m then clearly we may assume that G has no fixed points is${\Omega}$, and with this assumption it was shown in [4, Theorem 1]that the number t of G=orbits is at most 2m-1, each G-orbit has length at most 3m, and moreover|${\Omega}$|${\leq}$3m+t-1${\leq}$5m-2. Moreover it has recently been shown by P. S. Kim, J. R. Cho and C. E. Praeger in [1] that essentially the only examples with as many as 2m-1 orbits are elementary abelian 2-groups, and by A. Gardiner, A. Mann and C. E. Praeger in [2,3]that essentially the only transitive examples in a set of maximal size, namely 3m, are groups of exponent 3. (The only exceptions to these general statements occur for small values of m and are known explicitly.) Motivated by these results, we would decide what role if any is played by primes other that 2 and 3 for describing the structure of groups of bounded movement.

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A Study on the Calculation of the Area for Behavior as an Element in Planning the Floor Space of the Elderly Housing (노인주택 면적계획을 위한 요소로서 행위면적 산출 연구)

  • Lee, Youn-Jae;Lee, Hyun-Soo
    • Journal of the Korean housing association
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    • v.20 no.1
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    • pp.59-70
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    • 2009
  • The purpose of the study is to suggest the amount of space for each behavior according to the classification of behavior in the housing to plan the optimal floor space of the elderly housing. The method for calculating space for behavior begins with classifying behaviors, identifying them and then taking pictures of the model of elderly people who reproduce each behavior. Based on the pictures, body parts which are necessary for each behavior are assembled and the formula for behavioral space is created. The space for behavior is produced considering the body dimensions of Korean elderly in their sixty's as well as the furniture size and the psychological distance between people. 3D modeling is used to verify the result. Human behaviors can be classified into individual-related, housework-related, family-related, reception-related and other behaviors. These five behaviors are subdivided into more specific behaviors. The area for each specific behavior is calculated with the anthropometric data of the elderly, preferred furniture dimension and psychological area. As a result the required area for specific behaviors is as follows: the behavior of sleeping in a bed needs $4.3m^2$; the behavior of changing clothes on a chair, $1.7m^2$; the behavior of watching TV on the floor $1.3m^2$, the behavior of working and reading using a desk, $2.1m^2$, the behavior of exercise, $2.5m^2$; the behavior of showering on a chair, $1.3m^2$ and showering using a wheelchair, $1.9m^2$; the behavior of toileting using a wheelchair, $2.3m^2$; the behavior of washing up using a wheelchair, $1.9m^2$; the behavior of eating using a table for four persons, $4.4m^2$; the behavior of cooking and washing dishes, $0.9m^2$ per counter-top; the behavior of washing clothes using a washing machine, $0.9m^2$; the behavior of ironing on the floor $1.4m^2$; the behavior of reception(three persons) on the floor considering personal space, $4.0m^2$; the behavior of taking on and off shoes on a chair, $1.3m^2$. The result of the study is utilized as quantitative data to calculate optimal floor space for elderly housing. In addition, qualitative data such as characteristics of housing preference, spacial usage and storage capacity are necessary to produce the floor space which can provide convenient and safe living environment.

M/M/s/s + c Queueing System Revisited (M/M/s/s + c 대기시스템 재방문)

  • 김성철
    • Journal of the Korean Operations Research and Management Science Society
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    • v.21 no.2
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    • pp.49-58
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    • 1996
  • The generalized Erlang loss function, extensively studied in the literature, is revisited. We study the steady state loss probability in M/M/s/s + c queueing system and prove that it satisfies the first and second order properties in integral number of servers as well as integral queue capacities. Also we study the problem of allocating integral number of servers and queue capacities, and develop an algorithm to obtian an optimal allocation of them individually and jointly with the small number of computations.

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Effects of Nucleic Acid Related Compounds on Cytidine Deaminase Activity Produced by Bacillus subtilis ED 213 (Bacillus subtilis ED 213 Cytidine Deaminase 활성에 미치는 핵산관련물질의 영향)

  • 유대식;박정문;서태수;김정배;윤종국
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.28 no.1
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    • pp.87-93
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    • 1999
  • This study was carried out to investigate the effects of nucleic acid related compounds and metal ions on activities of cytidine deaminase from Bacillus subtilis ED 213. The purified cytidine deaminase was weakly inhibited by 1mM GMP, IMP and ATP, but not affected by other nucleic acid related compounds such as CMP and UDP. The apparent Km values for cytidine, deoxycytidine, 5 methylcy tidine, fluorodeoxycytidine, and 5 bromocytidine were calculated to be 6.6$\times$10-4M, 6.0$\times$10-4M, 0.9$\times$10-4M, 0.8$\times$10-4M, and 2.0$\times$10-3M, respectively. The cytidine deaminase was completely inhibited by 1mM Hg2+, and mildly inhibited over 40% by metal ions such as Na+ and Fe2+. However the enzyme activity was activated more than 40% by 1mM Mg2+.

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