• 제목/요약/키워드: loop space

검색결과 554건 처리시간 0.031초

Conformational Sampling of Flexible Ligand-binding Protein Loops

  • Lee, Gyu-Rie;Shin, Woong-Hee;Park, Hahn-Beom;Shin, Seok-Min;Seok, Cha-Ok
    • Bulletin of the Korean Chemical Society
    • /
    • 제33권3호
    • /
    • pp.770-774
    • /
    • 2012
  • Protein loops are often involved in diverse biological functions, and some functional loops show conformational changes upon ligand binding. Since this conformational change is directly related to ligand binding pose and protein function, there have been numerous attempts to predict this change accurately. In this study, we show that it is plausible to obtain meaningful ensembles of loop conformations for flexible, ligand-binding protein loops efficiently by applying a loop modeling method. The loop modeling method employs triaxial loop closure algorithm for trial conformation generation and conformational space annealing for global energy optimization. When loop modeling was performed on the framework of ligand-free structure, loop structures within $3\AA$ RMSD from the crystal loop structure for the ligand-bound state were sampled in 4 out of 6 cases. This result is encouraging considering that no information on the ligand-bound state was used during the loop modeling process. We therefore expect that the present loop modeling method will be useful for future developments of flexible protein-ligand docking methods.

Where is the coronal loop plasma located, within a flux rope or between flux ropes?

  • 임다예;최광선;이시백
    • 천문학회보
    • /
    • 제40권1호
    • /
    • pp.66.3-67
    • /
    • 2015
  • Without scrutinizing reflection, the plasma comprising a coronal loop is usually regarded to reside within a flux rope. This picture seems to have been adopted from laboratory plasma pinches, in which a plasma of high density and pressure is confined in the vicinity of the flux rope axis by magnetic tension and magnetic pressure of the concave inward magnetic field. Such a configuration, in which the plasma pressure gradient and the field line curvature vector are almost parallel, however, is known to be vulnerable to ballooning instabilities (to which belong interchange instabilities as a subset). In coronal loops, however, ideal MHD (magnetohydrodynamic) ballooning instabilities are impeded by a very small field line curvature and the line-tying condition. We, therefore, focus on non-ideal (resistive) effects in this study. The footpoints of coronal loops are constantly under random motions of convective scales, which twist individual loop strands quite randomly. The loop strands with the axial current of the same direction tend to coalesce by magnetic reconnection. In this reconnection process, the plasma in the loop system is redistributed in such a way that a smaller potential energy of the system is attained. We have performed numerical MHD simulations to investigate the plasma redistribution in coalescence of many small flux ropes. Our results clearly show that the redistributed plasma is more accumulated between flux ropes rather than near the magnetic axes of flux ropes. The Joule heating, however, creates a different temperature distribution than the density distribution. Our study may give a hint of which part of magnetic field we are looking to in an observation.

  • PDF

열진공 챔버용 폐회로 열제어시스템 설계 및 성능평가 (Design and Performance Test of a Closed Loop Thermal Control System for Thermal Vacuum Chamber)

  • 서희준;조혁진;박성욱;문귀원;정상헌;허환일
    • 한국항공우주학회지
    • /
    • 제44권1호
    • /
    • pp.88-97
    • /
    • 2016
  • 폐회로 열제어 시스템은 열진공 챔버의 온도를 $-150^{\circ}C{\sim}120^{\circ}C$와 같은 온도 조건으로 모사하기 위한 시스템으로, 극저온 블로워, 슈라우드, 히터, 극저온 밸브 등으로 구성된다. 본 연구는 우주 열환경 모사를 위한 폐회로 열제어 시스템의 설계 요소 정의 및 제어 변수별 실험 결과 등을 포함하고 있다. 폐회로 열제어 시스템 설계를 위해 설계 요소인 블로워 용량, 슈라우드 재질, 형태에 따른 특성 등의 분석을 수행 하였다. 폐회로 열제어 시스템의 극저온 블로워 필요 유량은 에너지 평형 방정식에 의해 결정되며, 제어는 작동 유체의 밀도 제어를 통해 제어된다. 밀도, 회전수와 같은 제어 변수별 실험을 통해 슈라우드 온도 분포 균질도 및 균일도를 측정하여 요구된 폐회로 열제어 시스템의 성능을 확인 하였다.

아라고 원판 시스템의 상태공간 모델 식별 (State-Space Model Identification of Arago's Disk System)

  • 강호균;최수영;최군호;박기헌
    • 대한전기학회:학술대회논문집
    • /
    • 대한전기학회 2000년도 하계학술대회 논문집 D
    • /
    • pp.2687-2689
    • /
    • 2000
  • In many cases the systems are so complex that it is not possible to obtain reasonable models using physical insight. Also a model based on physical insight contains a number of unknown parameters even if the structure is derived from physical laws. These problems can be solved by system identification. In this paper, Arago's disk system which has both stable and unstable regions is selected as an example for identification and a state-space model is identified using tailor-made model structure of this system. In stable region, a state-space model of Arago's disk system is identified through open loop experiment and a state-space model of unstable region is identified through closed loop experiment after using fuzzy controller to stabilize unstable system.

  • PDF

프린트형 반파장 소형 루프 안테나 (Printed Type Half-wavelength Small Loop Antenna)

  • 류홍균;우종명
    • 한국전자파학회:학술대회논문집
    • /
    • 한국전자파학회 2005년도 종합학술발표회 논문집 Vol.15 No.1
    • /
    • pp.245-248
    • /
    • 2005
  • In this paper, small sized half-wavelength circular loop antenna which attached beneath a visor of helmet is designed and fabricated at the resonant frequency of 449MHz. To reduce the size of the antenna, double series-shorted stubs are inserted inside the loop for practical use of a vacant space of loop inside. Also, It is designed for the printed type to install the helmet easily. The size of antenna on helmet is reduced to 87.75%(diameter : 70mm, height :.36mm) compare with general type antenna(diameter : 200mm height 101mm). The return loss, -10dB bandwidth and gain are -13.2dB, 17.6MHz(3.9%), and -1.78dBd. And, radiation pattern is omni-directional pattern at H-plane. Therefore, it can be seen that the half-wavelength circular loop antenna using double series-shorted stubs is proper structure for the miniaturization and the installed antenna of the helmet.

  • PDF

위성 관제용 반송파 복원부 설계 및 구현 (Design and Implementation of Carrier Recovery Loop for Satellite Telemetry and Tracking & Command)

  • 이정수;오치욱;서규재;오승한;채장수;명로훈
    • 한국항공우주학회지
    • /
    • 제39권1호
    • /
    • pp.56-62
    • /
    • 2011
  • 위성 트랜스폰더는 위성내부에 탑재되는 탑재체이며, 위성의 관제 및 제어를 위해 지상국과의 무선통신을 수행한다. 디지털 트랜스폰더는 기존의 아날로그 트랜스폰더에 비해 재제작이 쉬우며 정확한 성능 예측이 가능하다. 또한 변복조 방식, Data Rate, Loop Bandwidth, Modulation Index 등의 기능이 위성궤도 상에서 변경 가능하며, 많은 아날로그 부품을 디지털로 구현하여 무게 및 부피를 줄일 수 있다. 디지털 트랜스폰더의 핵심기술은 반송파 복원부이며, 반송파 복원부의 성능에 의해 Dynamic Range, 주파수 추적 범위, 주파수 추적 Rate 및 Coherent 등의 성능이 결정된다. 따라서 본 논문에서는 위성용 디지털 트랜스폰더에 적합한 반송파 복원부의 구조를 제안하고 이를 시험 및 검증하였다.

스트랩다운 탐색기 기반 호밍루프 설계 (Homing Loop Design for Missiles with Strapdown Seeker)

  • 홍주현;유창경
    • 한국항공우주학회지
    • /
    • 제42권4호
    • /
    • pp.317-325
    • /
    • 2014
  • 스트랩다운 탐색기를 장착한 유도탄의 경우 유도에 필요한 시선각속도 추출을 위해서는 탐색기 측정치인 관측각속도에서 동체각속도 성분을 보상해 주어야 한다. 관측각속도에 포함된 동체각속도와 동체각속도 성분의 보상에 사용되는 자이로 출력인 동체각속도의 신호 특성의 차이는 호밍루프의 불안정성을 야기한다. 본 논문에서는 자이로 출력에 탐색기 지연을 고려하여 보상신호의 특성을 일치시키고, 탐색기 지연에 오차가 있을 경우에도 전체 호밍루프의 안정화를 이루기 위해 유도명령 단에 PID제어기를 적용하는 호밍루프 설계방법을 제안하였다. 보상 전 후의 선형모델 대한 안정성해석을 수행하였고, 비선형 6자유도 시뮬레이션을 통해 설계된 호밍루프의 안정성과 성능을 검증하였다.

Performance Comparison of Three Different Types of Attitude Control Systems of the Quad-Rotor UAV to Perform Flip Maneuver

  • Lee, Byung-Yoon;Yoo, Dong-Wan;Tahk, Min-Jea
    • International Journal of Aeronautical and Space Sciences
    • /
    • 제14권1호
    • /
    • pp.58-66
    • /
    • 2013
  • This paper addresses the performance of three different types of attitude control systems for the Quad-rotor UAV to perform the flip maneuver. For this purpose, Quad-rotor UAV's 6-DOF dynamic model is derived, and it was used for designing an attitude controller of the Quad-rotor UAV. Attitude controllers are designed by three different methods. One is the open-loop control system design, another is the PD control system design, and the last method is the sliding mode control system design. Performances of all controllers are tested by 6-DOF simulation. In case of the open-loop control system, control inputs are calculated by the quad-rotor dynamic model and thrust system model that are identified by the thrust test. The 6-DOF realtime simulation environment was constructed in order to verify the performances of attitude controllers.

독립된 모달공간에서 양 위치피드백 제어기법의 강인성 (Robustness of Positive Position Feedback Control in the Independent Modal Space)

  • 황재혁;백승호
    • 소음진동
    • /
    • 제4권2호
    • /
    • pp.177-185
    • /
    • 1994
  • In this study, the effect of parameter errors on the closed-loop behavior of flexible structure is analyzed for IMSC(Independent Modal Space Control) with PPF(Positive Position Feedback). If the control force designed on the basis of structure model with the parameter errors is applied to control the actual system, the closed-loop performance of the actural system will be degraded depending on the degree of the errors. An asymptotic stability condition has been derived, using Lyapunov approach, which is independent of the dynamic characteristics of the structure being controlled. The extent of deviation of the closed-loop performance from the designed one is also derived and evaluated using operator techniques. It has been found that the extent of the deviation is proportational to the magnitude of the parameter errors, and that the proportional coefficient depends on the control algorithm.

  • PDF

U-loop emergence on the Sun

  • Magara, Tetsuya
    • 천문학회보
    • /
    • 제36권1호
    • /
    • pp.34.2-34.2
    • /
    • 2011
  • In this talk we explain U-loop emergence, in which U-shaped field lines emerge into the solar surface against gravitational force. In principle, they hardly emerge because mass tends to accumulate at the bottom of U-loops, thereby decreasing buoyancy. A key is found to be the shape of U-loops, that is, if U-loops have a shallow dip whose depth is of the order of the photospheric gravitational scale height, then a diverging flow is generated via a siphon-like mechanism by which the mass accumulated at the dip of the loops is drained out to enhance buoyancy. This successfully makes U-part of the loops emerge against gravity. We also discuss the relation between U-loop emergence and the so-called flux cancellation observed on the Sun in which opposite polarity regions apparently approach together and disappear.

  • PDF