• Asian Pacific Journal of Cancer Prevention
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• v.13 no.8
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• pp.3917-3925
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• 2012

Background: The relationship between postmenopausal hormone therapy (HT) and invasive breast cancer has been extensively investigated, but that with breast carcinoma in situ (BCIS) has received relatively little attention. The aim of our present study was to review and summarize the evidence provided by longitudinal studies on the association between postmenopausal HT use and BCIS risk. Methods: A comprehensive literature search for articles published up to May 2012 was performed. Prior to performing a meta-analysis, the studies were evaluated for publication bias and heterogeneity. Relative risk (RR) or odds ratio (OR) values were calculated using 14 reports (8 case-control studies and 6 cohort studies), published between 1986 and 2012. Results: There was evidence of an association between ever postmenopausal estrogen use and BCIS based on a random-effects model (RR = 1.25, 95% confidence interval (CI) = 1.01, 1.55). However, we found no strong evidence of an association between ever postmenopausal estrogen combined with progesterone use and BCIS using a randomeffects model (RR = 1.55, 95% CI = 0.95, 2.51). Furthermore, our analysis showed a strong association between "> 5 years duration" of estrogen or estrogen combined with progesterone use and BCIS. Furthermore, current use of any HT is associated with increased risk of BCIS in cohort studies. Additional well-designed large studies are now required to validate this association in different populations.

• Journal of Family Resource Management and Policy Review
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• v.20 no.1
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• pp.61-87
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• 2016

The purpose of this study is to demonstrate how having a family care program in the workplace for working women with preschool children affects these women's work and family life. This study employs a panel analysis based on data from the Korean Longitudinal Survey of Women and Families. The major results are as follows. First, financial support for nursery care is only significantly related to the turnover of married women with preschool children. Second, the negative effects of work on the family are significantly influenced by financial support for nursery care and maternity leave. Third, financial support for nursery care is also significantly related to the positive effects of work on the family. In conclusion, a family-friendly care program including financial support for nursery care and maternity leave in the workplace is an important support system for working mothers in raising their children.

• Journal of Korean Academy of Nursing
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• v.43 no.6
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• pp.791-800
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• 2013

Purpose: This study was done to test a structural equation modeling of case management outcomes in order to identify parameters affecting case management outcomes for the community-dwelling vulnerable elders. Methods: Data were collected from 309 nurses (case managers) and community-dwelling vulnerable elders (clients) from public health centers. For data analysis, descriptive statistics, Pearson correlation analysis, factor analysis, and covariance structure analysis were performed using SPSS Version 18.0 for Windows and Amos 16.0. Results: The hypothetical model had an acceptable fit: GFI=.97, CFI=.95, RMSEA=.02, SRMR=.05. The factor "case managers' singularity" had the greatest impact on case management outcomes in this model. In addition, the factor "case management practice" influenced case management outcomes; however, client characteristics did not. Case managers' singularity affected case management outcomes directly and indirectly, with case management practice mediating the latter effect. Conclusion: These results suggest that the causal relationship between case management outcomes and factors influencing these outcomes should be clarified through longitudinal research including a variety of client characteristics. In addition, in future studies, analysis of the effects of programs to improve manpower quality and examine the relationships among case management outcomes should be done.

• Asian-Australasian Journal of Animal Sciences
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• v.24 no.5
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• pp.603-609
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• 2011

Telomeres are special structures at the ends of eukaryotic chromosomes. Vertebrate telomeres consist of tandem repeats of conserved TTAGGG sequence and associated proteins. Birds are interesting models for molecular studies on aging and cellular senescence because of their slow aging rates and longer life spans for their body size. In this longitudinal study, we explored the possibility of using telomeres as an age-marker to predict age in Single Comb White Leghorn layer chickens. We quantified the relative amount of telomeric DNA in isolated peripheral blood lymphocytes by the Quantitative Fluorescence in situ Hybridization technique on interphase nuclei (IQ FISH) using telomere-specific DNA probes. We found that the amount of telomeric DNA (ATD) reduced significantly with an increase in chronological age of the chicken. Especially, the telomere shortening rates are greatly increased in growing individuals compared to laying and old-aged individuals. Therefore, using the ATD values obtained by IQ FISH we established the possibility of age prediction in chickens based on the telomere theory of aging. By regression analysis of the ATD values at each age interval, we formulated an equation to predict the age of chickens. In conclusion, the telomeric DNA values by IQ FISH analyses can be used as an effective age-marker in predicting the chronological age of chickens. The study has implications in the breeding and population genetics of poultry, especially the reproductive potential.

• Ocean Systems Engineering
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• v.9 no.4
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• pp.349-368
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• 2019

Triceratops is one of the new generations of offshore compliant platforms suitable for ultra-deepwater applications. Apart from environmental loads, the offshore structures are also susceptible to accidental loads. Due to the increase in the risk of collision between ships and offshore platforms, the accurate prediction of structural response under impact loads becomes necessary. This paper presents the numerical investigations of the impact response of the buoyant leg of triceratops usually designed as an orthogonally stiffened cylindrical shell with stringers and ring frames. The impact analysis of buoyant leg with a rectangularly shaped indenter is carried out using ANSYS explicit analysis solver under different impact load cases. The results show that the shell deformation increases with the increase in impact load, and the ring stiffeners hinder the shell damage from spreading in the longitudinal direction. The response of triceratops is then obtained through hydrodynamic response analysis carried out using ANSYS AQWA. From the results, it is observed that the impact load on single buoyant leg causes periodic vibration in the deck in the surge and pitch degrees of freedom. Since the impact response of the structure is highly affected by the geometric and material properties, numerical studies are also carried out by varying the strain rate, and the location of the indenter and the results are discussed.

• Journal of Korean Academy of Nursing
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• v.44 no.3
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• pp.259-269
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• 2014

Purpose: The purpose of this study was to construct and test a structural equation modeling on burnout of clinical nurses based on CS-CF model. Methods: A survey using a structured questionnaire was conducted with 557 clinical nurses. Data were analyzed using structural equation modeling. Results: The modified hypothetical model yielded the following ${\chi}^2=289.70$, p<.001, RMSEA=.09, GFI=.93, TLI=.91, CFI=.94, PCFI=.65, AIC=363.21, SRMR=.05 or less and showed good fit indices. Nursing work environment, patient safety culture and resilience showed indirect effects on burnout while compassion fatigue and compassion satisfaction had direct effects. Conclusion: Results of this study suggest that compassion fatigue must be decreased and compassion satisfaction has to be increased, while burnout is lowered by enhancing the clinical nursing work environment, patient safety culture and resilience. In addition, more variables and longitudinal studies are necessary to validate the clear cause-and-effect relationship between the relevant variables.

• Transactions of Materials Processing
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• v.11 no.2
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• pp.138-146
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• 2002

This paper is concerned with the simulation-based process design method involved non-steady state problem of tension levelling considering the elasto-plastic hardening behavior of a metallic strip by a commercial code ABAQUS/Standard. The tension levelling process is peformed to elongate the strip plastically in combination of tensile and bending strain by a controlled manner so that all longitudinal fibers in the strip have an approximately equal amount of length and undesirable strip shapes are corrected to the flat share. Objectives of this paper are the development of a general method for the design of a tension leveller by a finite element method and parameter studies for the deisgn variables such as the applied tension, the roll intermash includes the determination of the steady state using the simple unit of the tension levelling line and the effect of the finite element mesh size on the amount and distribution of the strain calculated. The analysis provides the information about the intermesh effect on the amount and final shapes of the strip and distribution of the strain in order to determine the amount elongation for correction of the irregular share.

• Journal of Biomedical Engineering Research
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• v.16 no.2
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• pp.149-156
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• 1995

This paper suggests a new experimental system and protocol of mechanical analysis for arterial cross-section research. So far, most methods of arterial studies have been focused on the deformation measurement in longitudinal and circumferential direction. The deformation in radial direction has been theoretically assumed by Poisson's ratio and/or the incompressibility of arterial wall. Also, the radial gradient of strains are neglected. In fact, the radial deformation and radial gradient of strains against blood pressure are important to be observed in the pathological point of view of artery. Proposed experimental system and protocol are to measure the deformation of cross-sectional artery. Also, this method enables to measure the deformation of anterior, posterior, and side site of cross-sectional area. It is meaningful to correlate the mechanically experimented data with pathological data of athroscIerotic artery.

• Journal of Korean Academy of Nursing Administration
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• v.20 no.5
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• pp.587-598
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• 2014

Purpose:This study was conducted to identify the effects of an action learning based creative problem-solving (CPS) course on problem solving, creativity and team-member exchange in nursing students. Methods: A quasi-experimental study applying a non-equivalent control group pre-post design was employed. Sophomore nursing students (32 in the experimental group and 33 in the control group) were recruited from a university in G-city, Korea. Problem solving, creativity and team-member exchange were measured for the pretest and posttest using self-report questionnaires. Kolmogorov-Smirnov test, Chi-square, Fisher's exact test, t-test, and ANCOVA with SPSS/Win 20.0 program were used to analyze the data. Results: The scores for problem solving, creativity and team-member exchange in the experimental group were significantly higher than those of the control group. Conclusion: Results of this study indicate that an action learning based CPS course is an effective teaching method to improve nursing students' competencies. In the future longitudinal studies are needed to assess the long term effects of the course.

• Journal of Families and Better Life
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• v.32 no.1
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• pp.1-12
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• 2014

The purpose of this study was to examine: (1) whether the level of parental monitoring changes during adolescence; (2) if it changes, what is the pattern of the change; and (3) whether the effects of adolescents' attachment to their parents on parental monitoring are dependent on time. Six waves of data from the Korea Youth Panel Study (KYPS) were used to address the research questions. The participants of the KYPS were 3,449 (1,725 boys and 1,724 girls) adolescents who participated in the study once a year for 6 years (from the 2nd grade in middle school until their high school graduation). Latent growth modeling (LGM) was used to analyze the data. The findings are as follows: the level of parental monitoring significantly increased over the six waves of the study, and the adolescents' attachment to their parents was a time-dependent predictor of parental monitoring. The results indicate that the quality of adolescents' attachment to their parents is an important factor that makes a difference in the level of parental monitoring by, possibly, affecting the level of adolescents' disclosure to their parents.