• Journal of Convergence for Information Technology
• /
• v.9 no.2
• /
• pp.155-164
• /
• 2019

In this study, 284 families of people with developmental disabilities responded to a survey about the importance of family support services and their recognition level of satisfaction. First, there was a statistically significant difference in the level of importance-satisfaction recognition of family support services for the people with developmental disabilities. Second, the recognition level of the importance of family support services of the people with developmental disabilities was in the order of support for parenting, support for physical and material wellbeing, support for family interaction. Third, satisfaction of family support services of the people with developmental disabilities was in the order of support for parenting activities, support for family interaction, support for emotional wellbeing. Fourth, we proposed the maintenance of the status quo, improvement efforts, and the need for mid-and long-term strategy by analyzing the characteristics of the importance-satisfaction quadrant. The results of this study are expected to be useful as basic data for improvement of family support services for the people with developmental disabilities.

• Journal of the Korean Recycled Construction Resources Institute
• /
• v.7 no.2
• /
• pp.131-137
• /
• 2019

The purpose of this study is to investigate the perception of buildings suspended from construction and to analyze the problems that are inherent and effective in the management of public officials and residents in the area where construction is suspended. There are 63 buildings in the Gangwon area, 16% of which are occupied by the whole area. 31% of the apartment houses are occupied the most, and 10 years or more is suspended. 241 of them accounted for 62%. In order to efficiently manage buildings that are suspended from construction, protection measures should be taken to ensure safety and prevent crime through periodic and continuous management of facility grade management that conforms to the special act on safety and maintenance of facilities. Effective support for budget and personnel is required for efficient management of construction suspended.

• The Journal of the Korea Contents Association
• /
• v.21 no.4
• /
• pp.773-784
• /
• 2021

The purpose of this study is to confirm the effectiveness of NCS-based education in the field of hair beauty applied in the educational field and to find ways to improve it. To this end, the importance of each NCS competency unit in the field of hair beauty evaluated by senior hair designers and the achievements of new designers evaluated by the IPA method were analyzed to explore the difference between importance-achievement and improvement plans through this. As a result of the study, NCS education in the field of hair beauty was found to be 6 items for improvement, 21 items for maintenance and strengthening, 14 items for long-term improvement, and 1 item for improvement consideration among the existing 41 competency units. In particular, the lack of creativity and the ability to collect and analyze the latest information, which should be improved urgently, appear, confirming the necessity of efforts to develop creative abilities as hair designers in the NCS education field.

• Korean Journal of Biological Psychiatry
• /
• v.27 no.2
• /
• pp.64-73
• /
• 2020

Suicidality is the most serious complication of mood disorders and psychosis; effective treatment should reduce suicide rates. The Organization for Economic Cooperation and Development age-standardized suicide rate in Korea was 22.6 in 2018, much higher compared to other countries worldwide. As mental and psychiatric problems are the main reasons for suicide attempts, accounting for 31.6% in 2018, targeting such problems should be the focus of efforts to reduce suicide rates. However, the ability of current pharmacotherapeutic and psychotherapeutic interventions to reduce suicide rates is limited due to their delayed effects. Therefore, electroconvulsive therapy (ECT) has been proposed as an alternative treatment. This approach is effective for treating most mental disorders associated with high suicide rates, including severe depression, bipolar disorder, and intractable psychotic disorders; ECT is also effective for Parkinson's disease, which has the highest suicide rate among all disorders in Korea. The acute, long-term, and prophylactic effects of ECT on suicidality have been reported in the literature, and treatment guidelines outside of Korea recommend that ECT be used at an early stage for rapid reduction of suicide rates, as opposed to being applied as a treatment of last resort. However, only ~0.092 of every 10000 members of the Korean general population received ECT in 2018; this is much lower than the average rate worldwide, of 2.2 per 10000. Elimination of obstacles to the use of ECT, early crisis intervention involving administration of ECT for rapid stabilization, and maintenance ECT to prevent recurrence should reduce suicide rates.

• The Journal of the Convergence on Culture Technology
• /
• v.8 no.4
• /
• pp.407-413
• /
• 2022

In this study, the empirical formula for evaluating cable tension based on long-term measurement for about 3 years according to temperature change was proposed by proving the correlation between the expansion joint displacement of the upper road bridge and the cable tension of the lower railway bridge. The tension prediction results using the empirical formula for tension evaluation each cables proposed in this study were found to be in good agreement with the cable tension using the vibration method within 3%. Therefore, it was analyzed that it could be applied together with the vibration method that was an experimental technique, to predict and evaluate the cable tension in serviced railway steel composite bridge. As a result of applying the estimated temperature calculated by the empirical formula for expansion proposed in this study to the empirical formula, it was analyzed that a high level of reliability could be secured when compared with the vibration method. Therefore, it is judged that the empirical formula for cable tension evaluation reflecting the estimated temperature proposed in this study can be used to predict the tension of cables according to climate change in the future and establish a maintenance plan.

• The Journal of the Korea Contents Association
• /
• v.22 no.10
• /
• pp.546-553
• /
• 2022

This research has focused on identifying a significant cause of the pavement cracks and irregularities of roads in Changwon city which have been constructed using steel slag, an auxiliary-based material. It is important to note that the cracks and irregularities yield logistics inconvenience, the risk of traffic accidents, and increased road maintenance costs. X-ray diffraction analysis tests have been conducted in this study on the sample collected by pavement cutting and excavating the three target roads. It is well known that the primary cause of the expansion of steelmaking slag is the hydration reaction between CaO and MaO. While the reaction of CaO is completed within a few months, that of MgO is pretty slow depending on the firing temperature. The test results reveal that the MgO content of the testing samples is approximately 47% of the total average, and that of CaO is around 14% of the total average. Hence, these results make it possible to be understood that the expansion induced by the slow hydration reaction of MgO results in road uplift in the long term, resulting in the cracks and irregularities of roads.

• Korean Journal of Schizophrenia Research
• /
• v.24 no.2
• /
• pp.60-67
• /
• 2021

Objectives: The optimal duration of maintenance treatment for patients with first-episode schizophrenia (FES) remains unclear. We examined the first antipsychotic treatment duration and its association with re-initiation of treatment using a nationwide claim database. Methods: Data from the Health Insurance Review and Assessment Service database in South Korea for 2007-2016 were used. Linear regression analysis and Cox proportional hazard models were used to evaluate the associations between the duration of the first antipsychotic treatment, time to re-initiation of treatment, and occurrence of treatment re-initiation. Results: Of 30,143 patients with FES, 80.4% (n=24,231) received <2 years of the first antipsychotic treatment. In patients who discontinued treatment (n=23,030), the rate of treatment re-initiation was 74.2% (n=17,086). As the duration of the first antipsychotic treatment increased, the time to re-initiation of treatment decreased (β=-0.146, p<0.001); however, the rate of treatment reinitiation was relatively constant (hazard ratio=1.001, p<0.001). Conclusion: Long-term antipsychotic treatment was not significantly associated with the rate of treatment re-initiation but showed a negative association with the time to re-initiation of treatment. Further research is needed to better understand the optimal treatment duration for FES.

• Korean Journal of Community Nutrition
• /
• v.27 no.4
• /
• pp.296-308
• /
• 2022

Objectives: This study aimed to develop evaluation criteria for the elementary-school-based health promotion program using the RE-AIM framework and to examine their feasibility. Methods: Previous evaluation studies on health interventions for elementary-school students using the RE-AIM framework were reviewed systematically to identify appropriate evaluation criteria. A diet and physical activity intervention based on the transtheoretical model was implemented in a pilot study using the "Happy Me" application. The feasibility of using the RE-AIM framework to evaluate it was examined. Results: The review yielded the following evaluation criteria: "reach," the ratio of participants out of the total target population; "efficacy/effectiveness," the difference in outcomes between the intervention and control groups, or between a pre- and post-test; "adoption," the rate of use of the program and participation in the next stage of the program; "implementation," the progress on the program components; "maintenance," the participants' and teachers' intention to continue using the program. The pilot study reached 76.6% of the targeted population. The intake of sugar-sweetened beverages decreased (P < 0.0001), and the duration of walking increased (P < 0.0001). Other indicators could not be evaluated; therefore, potential indicators were suggested. Conclusions: This study produced feasible evaluation criteria for elementary-school-based health promotion using the RE-AIM framework. Nevertheless, the feasibility needs to be validated with a broader range of studies and long-term interventions.

• BMB Reports
• /
• v.55 no.6
• /
• pp.287-292
• /
• 2022

The acute response to hypoxia is mainly driven by hypoxia-inducible factors, but their effects gradually subside with time. Hypoxia-specific histone modifications may be important for the stable maintenance of long-term adaptation to hypoxia. However, little is known about the molecular mechanisms underlying the dynamic alterations of histones under hypoxic conditions. We found that the phosphorylation of histone H3 at Ser-10 (H3S10) was noticeably attenuated after hypoxic challenge, which was mediated by the inhibition of aurora kinase B (AURKB). To understand the role of AURKB in epigenetic regulation, DNA microarray and transcription factor binding site analyses combined with proteomics analysis were performed. Under normoxia, phosphorylated AURKB, in concert with the repressor element-1 silencing transcription factor (REST), phosphorylates H3S10, which allows the AURKB-REST complex to access the MDM2 proto-oncogene. REST then acts as a transcriptional repressor of MDM2 and downregulates its expression. Under hypoxia, AURKB is dephosphorylated and the AURKB-REST complex fails to access MDM2, leading to the upregulation of its expression. In this study, we present a case of hypoxia-specific epigenetic regulation of the oxygen-sensitive AURKB signaling pathway. To better understand the cellular adaptation to hypoxia, it is worthwhile to further investigate the epigenetic regulation of genes under hypoxic conditions.

• Journal of Yeungnam Medical Science
• /
• v.40 no.1
• /
• pp.49-57
• /
• 2023

Background: Several previous studies have reported that quality of life (QoL) in hemodialysis patients affects mortality. However, the 36-item Short Form Health Survey, which has been used mainly in previous studies, is complicated in terms of questionnaire composition and interpretation. This study aimed to identify the impact of QoL on mortality in hemodialysis patients using an easier and simpler diagnostic tool. Methods: This retrospective study included 160 hemodialysis patients. QoL was evaluated using the World Health Organization Quality of Life Questionnaire-Brief version (WHOQOL-BREF). Psychosocial factors were evaluated using the Hospital Anxiety and Depression Scale, Multidimensional Scale of Perceived Social Support, Montreal Cognitive Assessment, and Pittsburgh Sleep Quality Index. We also evaluated medical factors, such as dialysis adequacy and laboratory results. Results: The mean hemodialysis vintage was 70.7±38.0 months. The proportion of patients who were elderly was higher in the mortality group than in the surviving group, and the Charlson Comorbidity Index score was also higher in the former group. Of the four domains of the WHOQOL-BREF, the physical health and psychological scores of the mortality group were significantly lower than those of the survival group. When the score in the physical health domain or psychological domain was ≤10, the 10-year mortality rate after hemodialysis initiation increased by approximately 2.3- and 2-fold, respectively. Conclusion: QoL may have a significant effect on mortality in patients undergoing hemodialysis. The WHOQOL-BREF is an instrument that can measure QoL relatively easily and can be used to improve the long-term prognosis of patients undergoing hemodialysis.