• Title/Summary/Keyword: liver lesion

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Historical Overview of Taenia asiatica in Taiwan

  • Ooi, Hong Kean;Ho, Chau-Mei;Chung, Wen-Cheng
    • Parasites, Hosts and Diseases
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    • v.51 no.1
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    • pp.31-36
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    • 2013
  • An overview of the epidemiological, biological, and clinical studies of Taenia and taeniasis in Taiwan for the past century is presented. The phenomenal observations that led to the discovery of Taenia asiatica as a new species, which differ from Taenia solium and Taenia saginata, are described. Parasitological surveys of the aborigines in Taiwan revealed a high prevalence of taeniasis, which might be due to the culture of eating raw liver of hunted wild boars. Chemotherapeutic deworming trials involving many patients with taeniasis were discussed. Praziquantel was found to be very effective, but sometimes complete worms could not be recovered from the feces after treatment, probably due to the dissolution of the proglottids. Atabrine, despite some side effects, can still be used, in properly controlled dosages, as the drug of choice for human T. asiatica infection if we need to recover the expelled worms for morphological examinations. Research results on the infection of T. asiatica eggs from Taiwan aborigines in experimental animals were also noted. Since the pig serve as the natural intermediate host of T. asiatica and the predilection site is the liver, a differential comparison of other parasitic pathogens that might cause apparently similar lesions is also presented.

Liver Resection for Hepatocellular Carcinoma Beyond BCLC A Stage

  • Tianqiang Song;Ti Zhang;Wei Zhang;Feng Fang;Qiang Wu;Yunlong Cui;Huikai Li;Qiang Li
    • Journal of Digestive Cancer Research
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    • v.4 no.2
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    • pp.92-98
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    • 2016
  • The barcelona clinic liver cancer (BCLC) staging systemis regarded as the optimal staging system to predict prognosis and guide treatmentfor hepatocellular carcinoma (HCC) .According to the BCLC classification, only patients with BCLC A stage should undergo liver resection. In contrast, patients with intermediate-advanced HCC should be scheduled for palliative therapies,such as transcatheter arterial chemoembolization (TACE) and target therapy, even if the lesion is resectable. More and more studies report good short-term and long-term outcomes in patients with intermediate-advanced HCC treated by radical resection and many patients benefited from curative resection. The aim of this review was to evaluate the role of surgery beyond the BCLC recommendations. A revision of the BCLC algorithm should be proposed.

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Solitary Necrotic Nodule of the Liver Mimicking Metastasis in Patient with Early Gastric Cancer : 3T MRI and PET/CT Findings (조기 위암 환자에서 전이암과 감별이 필요했던 간내 단발성 궤사성 결절: 3T MRI 및 PET/CT 소견)

  • Cho, Woo-Sun;Kim, Gi-Hyeon;Lee, Hwa-Yeon;Lee, Jong-Beum;Kwon, Gui-Young
    • Investigative Magnetic Resonance Imaging
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    • v.13 no.2
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    • pp.213-217
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    • 2009
  • Solitary necrotic nodule (SNN) of the liver is a very uncommon benign lesion, and it is detected incidentally as a rule. It is important to differentiate SNN radiologically from various single hepatic nodules because SNN mimics hepatic metastasis, especially in staging work up of known primary malignancy. The reported imaging findings of SNN are well-defined nodule without enhancement or with subtle peripheral enhancement. There has been no report about the target-like SNN of the liver and about the imaging finding of 3T magnetic resonance imaging and positron emission tomography. We report a case of targetlike SNN of the liver, mimicking hepatic metastasis, with findings of various imaging modalities and try to find a cause of this nodule according to the pathologic and literature review.

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A Case of with Transient splenic Hot Uptake on $^{99m}Tc$-Methylene Diphosphonate(MDP) Bone Scan Following Blunt Abodominal Trauma with Underlying Liver Cirrhosis (간경변환자에서 복부외상후 일시적으로 관찰된 $^{99m}Tc$-MDP Bone Scan의 비장 섭취 1예)

  • Won, Jong-Hyeon;Kim, Jae-Myung;Kim, Jung-Han;Choo, Gil-Yeon;Park, Seok-Oh;Sung, Sang-Kyu;Choi, Dae-Seob;Kim, Chin-Seung
    • The Korean Journal of Nuclear Medicine
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    • v.27 no.2
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    • pp.309-314
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    • 1993
  • We report a case of 33-year-old man with a transient splenic uptake who had traumatic multiple rib fractures and hernoperitoneum combined with underlying liver cirrhosis, liver cirrhosis with liver bed laceration and splenomegaly without any other demonstrable splenic lesion due to traffic accident was found by abdominal ultrasound and surgery. Incidentally, $^{99m}Tc$-MDP Bone scan showed whole prominent splenic uptake, spleen was also visible on $^{99m}Tc$ Tin colloid liver scan. We suggest the splenic uptake of the radionuclide temporary splenic infarct to the transient total splenic infarction or unknown traumatic effect.

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Acute Suppurative Pericarditis Caused by Liver Abscess -1 case report- (간농양에 속발한 급성화농성 심 낭염 -1례 보고-)

  • 홍장수;노윤우
    • Journal of Chest Surgery
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    • v.29 no.7
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    • pp.785-788
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    • 1996
  • Pericardial abscess due to liver abscess is a very rare disease, the result of which is usually fatal when untreated. But a combination of antibiotics therapy and pericardial drainage has broug t good result. A 32-year-old man was admitted to the emergency room because of fever and chilling sensation. Chest X-ray showed cardiomegaly and a mass lesion In the left lobe of liver on ultrasonography. The echocardiography revealed impending cardiac tamponade. Pus drainage of the liver abscess through per- foration of right diaphram and pericardiotomy were performed. The pericardium was thickened and 600 ml of purulent fluid and necrotic debris were drained. Fibrin clots were firmly attached to the undelying myocradium. Histological examination of the pericardium showed acute inflammation with microabsscess and Escherichia soli was cultured from pericardial pus. He was discharged after 4 weeks on antibiotics, but Doppler echocardiograpy revealed a slightly thickened pericardium with a mild constrictive physiology.

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Studies on the rabbit viral hepatitis I. Electron microscopic observation of the acute hepatic lesions in experimentally infected rabbit (토끼의 바이러스성(性) 간염(肝炎)에 관(關)한 연구(硏究) I. 실험적(實驗的) 감염토(感染兎)의 급성간염조직(急性肝炎組織)의 전자현미경적(電子顯微鏡的) 관찰(觀察))

  • Lee, Cha-soo;Park, Cheong-kyu
    • Korean Journal of Veterinary Research
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    • v.29 no.4
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    • pp.531-540
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    • 1989
  • A new sudden death in rabbits appeared in China and Korea in 1984 and 1985, respectively, and was recognized to be an acute infectious disease caused by a virus. The disease was reported as a "new viral disease," and thereafter, a tentative name of "viral hemorrhagic disease", "hemorrhagic pneumonia" or "viral hemorrhagic pneumonia" has been described in the case reports. But authors had called the viral disease "rabbit viral hepatitis" due to picornavirus infection, because the principal lesion of the disease was an acute hepatitis. The purpose of this report is to describe the electron microscopic findings on the livers in experimentally infected rabbits. All the livers of the affected rabbits were shown to have degenerative changes of a type that is characteristic of acute hepatitis. In the liver cells, there were dilation of rER and mitochondria, vacuole formation of various sizes, and appearances of many virus-like particles in the vicinity of rER, granular bodies and crystalline arrays of viral particles in the cytoplasm with necrotic changes of the nucleus. Clusters of virus-like particles and viral crystals appeared in the cytoplasm of sinusoid endothelial cells and Kupffer's cells with morphological changes of organelles. Also viral crystals were demonstrated in the cytoplasm of macrophages among the liver cells. On the whole, the liver cells had many virus-like particles and a few crystalline arrays of viral particles. Therefore, this implies that the liver cells are the main site of the viral replication in inducing the viremia. It was concluded that the liver was the primary target organ of this viral disease, and the pathological and the ultrastructural evidence suggest that the virus may be belong to genus enterovirus.

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Evaluation of Significance of Diffusely Increased Bilateral Renal Uptake on Bone Scan (골스캔상 신장의 미만성 방사능집적 증가소견의 임상적 의의)

  • Sung, Mi-Sook;Yang, Woo-Jin;Byun, Jae-Young;Park, Jung-Mi;Shinn, Kyung-Sub;Bahk, Yong-Whee
    • The Korean Journal of Nuclear Medicine
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    • v.24 no.1
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    • pp.119-123
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    • 1990
  • Unexpected renal abnormality can be detected on bone scan using Tc-99m-MDP. The purpose of the study is to evaluate the diagnostic significance of diffusely increased bliateral renal uptake on bone scarf. 1,500 boor scan were reviewed and 43 scans which showed diffusely increased bliateral renal uptake were selected for analysis. Laboratory findings for renal and liver function tests including routine urinalysis were reviewed in 43 patients. 26 of 43 case showed abnormality in urinalysis and renal function stud 20 of 43 cases showed abnormal liver function study and 3 of these cases were diagnosed as hepatorenal syndrome later. 13 of those 20 cases had liver cirrhosis with or without hepatoma. 12 of 43 cases showed abnormality both in renal and liver function studies. 2 of 43 cases showed diffusely increased bilateral renal uptake after chemotherapy for cancer but not on previous scans before chemotherapy. 2 of 43 cases showed hypercalcemia and 8 of 43 cases had multifocal bone uptake due to metastasis or benign bone lesion. but the latter showed no hypercalcemia at all. There was no significant correlatrion between increased renal uptake and MDP uptake in soft tissue other than kidneys. This study raised the possibility that the impaired liver and/or renal function may result in diffuse increase of bliateral renal uptake of MDP of unknown mechaninsm. It seems to need further study on this correlation.

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Inferior Vena Cava Stenosis Following Orthotopic Liver Transplantation: Differentiating Points from False Positives (뇌사자 간이식 후 발생한 하대정맥 협착: 위양성과의 감별점)

  • Yeonsoo Choi;Jin Hyeok Kim;Ung Bae Jeon;Joo Yeon Jang;Tae Un Kim;Hwaseong Ryu
    • Journal of the Korean Society of Radiology
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    • v.84 no.3
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    • pp.713-718
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    • 2023
  • Orthotopic liver transplantation has become the treatment of choice for patients with end-stage liver disease. Various early or delayed vascular complications, including arterial pseudoaneurysm, thrombosis, or stenosis, and venous stenosis or occlusion, may lead to graft failure. Early detection and prompt management of such complications are essential to achieve successful transplantation and prevent the need for retransplantation. This report presents differentiating points, using computed tomography and digital subtraction angiography findings and measurement of pressure gradient across the stenotic lesion, that require immediate intervention in patients with inferior vena cava stenosis after orthotopic liver transplantation.

Focal Lesion Detection of SPIO-specific agent Compared with Optimized Pulse Sequences in the Hepatic Metastases: Case Review (간 전이환자에서 최적의 펄스시퀀스에 따른 SPIO 특이성 조영제의 국소병변검출: Case review)

  • Goo, Eun-Hoe
    • Korean Journal of Digital Imaging in Medicine
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    • v.14 no.2
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    • pp.57-61
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    • 2012
  • To compare the accuracy of breath-hold magnetic resonance imaging sequences to establish the most effective superparamagnetic iron oxide-enhanced sequence for detection of hepatic metastases. A total of 100 patients(50men and 50women, mean age: 60years) with liver disease(including malignant and benign liver lesions) were investigated at 3.0T machine (GE, General Electric Medical System, Excite HD) with 8Ch body coil. Pulse sequence for MR imaging decided to the FS-T2-FSE-RT(TR/TE/Thick./Freq./Phase=12857ms/100ms/7mm/512/384), MGRE(TR/TE/Thick./Freq./Phase=100ms/9.7ms/7mm/384/288), in-out of phase echo(TR/$TE_1$, $TE_2$/Thick./Freq./Phase=140ms/2.4, 5.8ms/7mm/352/300), Images obtained before the injection of SPIO. Six sequences were optimized for lesion detection: FS-T2-FSE-RT, multigradient recalled echo data image(MGRE), T2-weighted MGRE with an 9.7msec echo time. Images were reviewed independently by five blinded observers. The accuracy of each sequence was measured by using picture archiving communication system analysis. All results were correlated with findings at multidectator computed tomography examination. Differences between the mean results of the six observers were measured by using paired student t-test analysis. Postcontrast T2-weighted MGRE sequences were the most accurate and were significantly superior to postcontrast FS-T2-FSE-RT, T2-weighted MGRE, in-out of phase MR sequences(p < .05). For all lesions that were malignant or smaller than 1 cm, respectively, contrast to noise ratio of pre and postcontrast sequences were -1and -0.3 for T2-weighted FSE, 0.53 and 4.5 in-out of phase, 7, 7.08, 5.08, 3.32, 1.7, 1.16, 0.79, 0.68 for GRE with 2.9, 7.5, 12.1, 16.6, 21.2, 25.8, 30.4, 35.0 TE values. Breath-hold various TE precontrast sequences offer improvement in sensitivity compared with fixed multigradient recalled echo sequences alone.

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Classification Algorithm for Liver Lesions of Ultrasound Images using Ensemble Deep Learning (앙상블 딥러닝을 이용한 초음파 영상의 간병변증 분류 알고리즘)

  • Cho, Young-Bok
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.20 no.4
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    • pp.101-106
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    • 2020
  • In the current medical field, ultrasound diagnosis can be said to be the same as a stethoscope in the past. However, due to the nature of ultrasound, it has the disadvantage that the prediction of results is uncertain depending on the skill level of the examiner. Therefore, this paper aims to improve the accuracy of liver lesion detection during ultrasound examination based on deep learning technology to solve this problem. In the proposed paper, we compared the accuracy of lesion classification using a CNN model and an ensemble model. As a result of the experiment, it was confirmed that the classification accuracy in the CNN model averaged 82.33% and the ensemble model averaged 89.9%, about 7% higher. Also, it was confirmed that the ensemble model was 0.97 in the average ROC curve, which is about 0.4 higher than the CNN model.