• 한국전산구조공학회논문집
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• 제30권6호
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• pp.507-514
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• 2017

건축분야에서 BIM이 널리 사용되면서, 토목구조물에 BIM을 적용하려는 노력이 최근 급속히 증가하고 있다. 그러나 기존 상용 BIM 소프트웨어의 기능은 건물 등의 건축물 중심으로 특화되어 있기 때문에 선형 중심의 토목구조물에 적용하기에 많은 어려움이 따른다. 본 연구에서는 철도 궤도부의 객체 정보를 관리하기 위하여 선형을 다룰 수 있는 소프트웨어와 BIM 소프트웨어간의 정보공유를 통해 캔트가 반영된 정보모델 생성방법을 제시하였다. 철도 궤도부 모델링은 궤도부 구조물을 연속 구조물과 비연속 구조물로 분류한 후, 연속 구조물을 선형 소프트웨어에서 생성하고, 이후 공유된 선형정보를 이용하여 비연속 구조물의 정보모델을 생성하는 절차로 이루어진다. 이 때 비연속 구조물은 BIM 소프트웨어에 전달한 이산화된 궤도 선형 및 캔트 정보를 바탕으로 비연속 구조물 각각의 위치, 회전 정보를 계산하는 알고리즘을 통하여 생성된다. 본 연구에서 제시한 방법을 오송 철도종합시험선로에 적용하여 그 실용성을 검증하였으며, 생성된 정보모델을 기반으로 명확한 객체 식별과 속성정보 추출 및 객체별 물량산출이 가능함을 확인하였다.

• Bulletin of the Korean Chemical Society
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• 제29권4호
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• pp.805-810
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• 2008

Using metallic Ti powder as raw materials and 1,2-diaminocyclohexane (DACH) as the trial template, two novel reduced titanophosphate open-structures were hydrothermally isolated by varying the $H_3PO_4/H_2O$ ratio to adjust the pH value. TiPO-1 crystallizes in orthorhombic Pbca space group with cell parameters a = 21.956(3) $\AA$, b = 8.6268(11) $\AA$, c = 7.2883(9) $\AA$, V = 1380.5(3) $\AA^3$, Z = 4. TiPO-2 crystallizes in triclinic space group P$\bar{1}$ with parameters a = 5.1620(10) $\AA$, b = 8.815(2) $\AA$, c = 10.655(3) $\AA$, $\alpha$ = $99.45^{\circ}$, $\beta$ = $102.94^{\circ}$, $\gamma$ = $91.06^{\circ}$, V = 465.34 $\AA^3$. TiPO-1 is constructed by infinite -Ti-O-Ti-O- linkage that is capped by $PO_4$ groups to form a chain structure with protonated DACH molecules occupying the interchain spaces. TiPO-2 represents a rare 3-D reduced titanophosphate with 12-MR channels. The structure of TiPO-2 is a neutral framework with water molecules located in the channels.

• Macromolecular Research
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• 제17권2호
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• pp.84-90
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• 2009

We prepared side-chain liquid crystalline polymers comprising two monomeric units, one having a mesogenic side group that could form a smectic mesophase and the other having a phenolic group attached to the polymer backbone via a thermally reversible urethane bond. The urethane linkage between the isocyanate and phenol groups was stable at room temperature, but it cleaved to generate an isocyanate group when the temperature was increased. When annealed, the copolymers in their smectic mesophases became insoluble in common organic solvents, suggesting the formation of network structures. XRD analysis showed that the annealed polymers maintained their smectic LC structures. The crosslinking process probably proceeded via the reaction of the dissociated isocyanate groups. Some of the isocyanate groups would have first reacted with moisture in the atmosphere to yield amino groups, which underwent further reaction with other isocyanate groups, resulting in the formation of urea bonds. We presume that only polymer chains in the same layer were crosslinked by the reaction of the isocyanate groups, resulting in the formation of a layered polymer network structure. Reactions between the layers did not occur because of the wide layer spacing.

• Bulletin of the Korean Chemical Society
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• 제14권2호
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• pp.200-206
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• 1993

Structures of two polymorphs of ${\alpha},{\alpha}$-trehalose octaacetate monohydrate, $C_{28}H_{38}O_{19}\;{\cdot}\;H_2O$, have been studied by X-ray diffraction method. ${\alpha},{\alpha}$-trehalose (${\alpha}$-D-glucopyranosyl ${\alpha}$-D-glucopyranoside) is a nonreducing disaccharide. The polymorph I belongs to the monoclinic $P2_1$, and has unit cell parameters of a=10.725(l), b=15.110(4), c=11.199(5) ${\AA}$, ${\beta}=108.16(2)^{\circ}$ and Z=2. The polymorph II is orthorhombic $P2_12_12_1$, with a=13.684(4), b=15.802(4), c=17.990(9) ${\AA}$ and Z=4. The final R and R$_w$ values for monoclinic polymorph I are 0.043 and 0.048 and for orthorhombic polymorph II are 0.116 and 0.118, respectively. Those R values of polymorph II are high because the large thermal motions of acetyl groups and the poor quality of the crystal. The molecular conformations in the two polymorphs are similar. Both D-glucopyranosyl rings have chair $^4C_1$ conformations and atoms of glycosidic chain ${\alpha}(1{\rightarrow}1)$ linkage are coplanar. The primary acetate groups of the pyranose residues assume both gauche-trans conformations. The molecules of two polymorphs have pseudo-C$_2$ symmetry at glycosidic O(1) atom. The bond lengths and angles are normal compared with those in other acetylated sugar compounds. The molecules in the monoclinic crystal are held by the hydrogen bonds with the water molecules and by van der Waals forces.

• 대한방사성의약품학회지
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• 제3권2호
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• pp.54-58
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• 2017

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry(MALDI-TOF MS) is one of the powerful methods that enable analysis of small molecules as well as large molecules up to about 500,000 Da without severe fragmentation. MALDI-TOF MS, thus, has been a very useful an analytical tool for the confirmation of synthetic molecules, probing PTMs, and identifying structures of a given protein. In recent nuclear medicine, MALDI-TOF MS liner ion mode helps researcher calculate the average number of chelator(or linkage) per an antibody conjugate, such as DOTA-(or DFO-) trastuzumab for labeling a medical radioisotope. This simple technique can be utilized to improve the labeling method and control the quality at the development of antibody-based radiopharmaceuticals, which is very effected to diagnosis and therapy for in vivo tumor cells, with radioisotopes like $^{89}Zr$, $^{64}Cu$, and 177Lu. To minimize the error, MALDI-TOF MS measurement is repeatedly performed for each sample in this study, and external calibration is carried out after data collection.

• 한국강구조학회 논문집
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• 제15권1호
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• pp.41-50
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• 2003

구조물에 대한 비파괴 손상평가는 손상 전과 손상 후의 동적 특성으로부터 손상의 위치와 그 크기에 대한 정보를 제공한다. 기존 구조물의 시스템 신뢰도를 추정하기 위해서는 이러한 비파괴 손상평가의 결과가 부재요소의 파괴확률에 반영되어야 한다. 구조 부재의 파괴확률은 각 부재의 파괴함수로부터 신뢰성 이론을 이용하여 구할 수 있다. 본 논문에서는 각 부재의 파괴확률로부터 직접 구조 시스템의 파괴확률을 구할 수 있는 식을 제안하였다. 손상평가와 신뢰성평가 분야의 연계는 철골조 단층 프레임의 수치해석 모델에 인위적인 손상을 가하여 손상 전과 손상 후의 모달 변수를 이용하여 그 타당성을 입증하였다.

• 한국산학기술학회논문지
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• 제11권4호
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• pp.1367-1372
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• 2010

유연한 곁사슬을 가지고 있는 copoly(ether-ether-ester)가 중축합반응에 의하여 합성되었다. 테트라클로로에탄 중에서 측정된 중합체의 고유점성도 값은 0.42~0.78 dl/g을 나타내었다. 합성된 고분자의 구조는 $^1H$-NMR과 FT-IR에 의하여 조사되었으며, 열적성질과 액정성은 DSC, TGA, POM, XRD에 의하여 측정되었다. 조사된 결과에 의하면 합성된 공중합체들은 모두 단독중합체보다 낮은 용융전이온도를 나타내었으며, 공중합체 내의 비페닐렌 단위의 함량이 60 mol %이상일 때 네마틱액정상이 관찰되었으며, 합성된 중합체의 액정성은 비페닐렌 함량에 의존하였다.

• Journal of Microbiology and Biotechnology
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• 제10권2호
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• pp.267-271
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• 2000

Abstract Two glucans (PONGa and PONGb) differing in their anomeric and glycosidic linkage structures were isolated from the water-insoluble materials (PON) of Pleurotus ostreatus basidiocarps, which activated the complement system and were almost soley composed of D-glucose. The isolatIon was achieved by repeated precipitations with ethanol and adsorption on concanavalin A (Con A) of paN suspension in thymol/NaCL Based on methylation analysis. IR, GLC-MS, $^1H,{\;}and{\;}^{13}C-NMR$ spectroscopies, PONGa was found to be a branched a-glucan composed of ${\alpha}-linked$ D-glucopyranose residues and ${\alpha}-linked$ units with 6-branching points, whereas PONGb was a linear ${\beta}-1,3-glucan$ composed mainly of ${\beta}-1,3-linked$ D-glucopyranose residues. The PONGb particles reacted more potently than the PONGa particles as C3 activator in alternative complement hemolysis and crossed-immunoelectrophoresis using anti-human C3, thereby suggesting that the complement activating components of PON were ${\beta}-(13)-glucans rather$ than ${\alpha}-glucan$ components.onents.

• Journal of Microbiology and Biotechnology
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• 제21권5호
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• pp.449-454
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• 2011

The infection of pandemic influenza viruses such as swine flu (H1N1) and avian flu viruses to the host cells is related to the following two factors: First, the surface protein such as HA (hemagglutinin) and NA (neuraminidase) of the influenza virus. Second, the specific structure of the oligosaccharide [sialic acid(${\alpha}2$-6) galactose(${\beta}1$-4)glucose or sialic acid(${\alpha}2$-3)galactose(${\beta}1$-4)glucose] on the host cell. After recognizing the specific structure of the oligosaccharide on the surface of host cells by the surface protein of the influenza virus, the influenza virus can secrete sialidase and cleave the sialic acid attached on the final position of the specific structure of the oligosaccharide on the surface of host cells. Tamiflu (oseltamivir), known as a remedy of swine flu, has a saccharide analog structure, especially the sialic acid analog. Tamiflu can inhibit the invasion of influenza viruses (swine flu and avian flu viruses) into the host cells by competition with sialic acid on the terminal position of the specific oligosaccharide on the surface of the host cell. Because of the emergence of Tamiflu resistance, the development of new potent anti-influenza inhibitors is needed. The inhibitors with positive-charge groups have potential as antiviral therapeutics, and the strain specificity must also be resolved.

• Smart Structures and Systems
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• 제17권3호
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• pp.413-429
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• 2016

The recent research on proper orthogonal decomposition (POD) has revealed the linkage between proper orthogonal modes and linear normal modes. This paper presents an investigation into the modal identifiability of an instrumented cable-stayed bridge using an adapted POD technique with a band-pass filtering scheme. The band-pass POD method is applied to the datasets available for this benchmark study, aiming to identify the vibration modes of the bridge and find out the so-called deficient modes which are unidentifiable under normal excitation conditions. It turns out that the second mode of the bridge cannot be stably identified under weak wind conditions and is therefore regarded as a deficient mode. To judge if the deficient mode is due to its low contribution to the structural response under weak wind conditions, modal coordinates are derived for different modes by the band-pass POD technique and an energy participation factor is defined to evaluate the energy participation of each vibration mode under different wind excitation conditions. From the non-blind datasets, it is found that the vibration modes can be reliably identified only when the energy participation factor exceeds a certain threshold value. With the identified threshold value, modal identifiability in use of the blind datasets from the same structure is examined.