• Journal of the Korean Society for Railway
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• v.11 no.6
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• pp.550-561
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• 2008

The purpose of this paper is to propose a new transit assignment model for intercity rail networks. The characteristics of intercity rail are different from that of public transit in urban area. Line selection probability on route section is introduced to include the characteristics of intercity rail into transit assignment model. Network expansion is more simplified by a assumption line selection probability is externally given. The generalized cost is used to decide the volume of each transit line in most of existing transit assignment models. But, many variables have influence on the volume of each line such as time schedule of transit lines, inter-station distance, passengers' income, seasonal variation of demand and regional characteristics. The influence of these variables can be considered to decide the volume of each line by introducing line selection probability on route section. The tests on a small scale network show that the model proposed in this paper is superior to existing models for predicting intercity rail demand. Proposed model is suitable to consider the complicated fare structure of intercity rail and to draw inter-station demand directly as a result of assignment procedure.

• Journal of the Korean Institute of Telematics and Electronics D
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• v.36D no.11
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• pp.12-17
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• 1999

In this paper, we proposed a novel CB-CPW(Conductor Backed CPW) for suppression of crosstalk caused by PPL(Parallel Plate Line) mode in the millimeter wave frequency. The proposed structure is formed by the GaAs main substrate attached on the Si lossy layer. The PPL mode can be suppressed by the Si lossy layer of conductivity ${\sigma}$, and it reduces the crostalk between the nearby transmission lines. Using 200 um thick Si substrate of ${\sigma}$ = 30S/m, as the lossy layer, the crosstalk can be suppressed below - 40 dB at 60 GHz. The proposed method is costly effective because inexpensive Si wafer is employed to suppress the PPL mode, and it can be used in the various types of millimeter wave applications.

• Proceedings of the Korean Vacuum Society Conference
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• 2014.02a
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• pp.254.1-254.1
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• 2014

Atmospheric plasma's electron temperature is less than thermal plasma, so it is useful at bio experiment. We have investigated the optical emission spectroscopy (OES) lines by spectrometer during Atmospheric plasma bombardment onto the PBS surface by using an Ar gas flow. Also we have measured the OH radical density inside the solution induced by the Atmospheric plasma bombardment. OH radical species are appeared at 308 nm and 309 nm. Densities of OH radical species has been found to be significantly decreased versus depth of the solution from 2 mm to 6 mm. OH radical density inside the PBS is measured to be about $1.87{\times}1016cm-3$ downstream at 2 mm from the surface under optimized Ar gas flow of 200 sccm in Atmospheric plasma. Also we have investigated cell viability of lung cancer and normal cell after Atmospheric plasma treatment for fixed exposure time in 60 seconds, but different depths. We used SEM, we observed change of cell morphorogy, did experiment about FDA & PI Staining method. It is found that there is selectivity between the lung cancer and lung normal cell, in which cancer cell definitely has higher cell death ratio more than normal cell. We have investigated change of bond structure in FT-IR spectroscopy, the following peaks were observed: and intense O-H peak at 3422 cm-1 and at 2925 cm-1 corresponds to C-H stretch vibrations of methylene group.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.44 no.4 s.316
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• pp.86-92
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• 2007

A discrete dynamic model for tracking feature points in 2D images is developed. Conventional snake approaches deform a contour to lock onto features of interest within an image by finding a minimum of its energy functional, composed of internal and external forces. The neighborhood around center snaxel is a space matrix, typically rectangular. The structure of the model proposed in this paper is a set of connected vertices. Energy model is designed for its local minima to comprise the set of alternative solutions available to active process. Block on tracking is one dimension, line type. Initial starting points are defined to the satisfaction of indent states, which is then automatically modified by an energy minimizing process. The track is influenced by curvature constraints, ascent/descent or upper/lower points. The advantages and effectiveness of this layer approach may also be applied to feature points tracking of digital image whose pixels have one directional properties with high autocorrelation between adjacent data lines, vertically or horizontally. The test image is the ultrasonic carotid artery image of human body, and we have verified its effect on intima/adventitia starting points tracking.

• IMMUNE NETWORK
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• v.3 no.2
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• pp.156-163
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• 2003

Background: $\beta$-1,3-glucans are well known to enhance the immune reactions, resulting in antitumor, antibacterial, antiviral, anticoagulatory and wound healing activities. $\beta$-1, 3-glucans have various activities depending on molecular weight, degree of branching, conformation, water-solubility and intermolecular association. However, the $\beta$-1,3-glucan linked backbone structure is essential and $\beta$-D-glucopyranosyl units are required for immuno-potentiating activities. Result: In this study, we tested the immunophamacological activities of soluble $\beta$-1,3-glucans and confirmed the following activities: (1) $IFN-{\gamma}$ production in PBMCs in the presence or the absence of PHA, LPS, or IL-18; (2) induction of various cytokines in the spleen and thymus; (3) adjuvant effect on the antibody production; (4) nitrogen oxide synthesis in macrophages; (5) the cytotoxic and antitumor effects on cell lines and ICR mice. Conclusion: These results strongly suggested that $\beta$-1,3-glucans possessed various immuno-pharmacological activities.

• Proceedings of the KSR Conference
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• 2011.10a
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• pp.374-374
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• 2011

Recently the construction of railway sections passing the central area of cities and stations under railway lines are increasing, and then it is urgently required to take the countermeasures against the railway vibration and the second-phase noise radiated from it. The most efficient countermeasure, out of technologies developed up to now, is the floating slab track which is the track system isolated from the sub-structure by springs. In other countries, the source technologies for anti-vibration design and vibration isolator - one of key components - have been developed and many installation experiences have been accumulated. However, in Korea, since the system design technology and technologies for key components are not yet developed, the foreign system are being introduced without any adjustment, and the key component, vibration isolator, depends on imports. In this study, based on the results of previous studies of the dust-control device installation using the slab and go through time after lifting impressive when stepped on power generated by the cross-section of the slab and shear connection re-examined the structural stability.

• BMB Reports
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• v.51 no.12
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• pp.630-635
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• 2018

C-X-C motif chemokine ligand 2 (CXCL2) is a small secreted protein that exhibits a structure similar to the proangiogenic subgroup of the CXC chemokine family. Recently, accumulating evidence suggests that chemokines play a pivotal role in cancer progression and carcinogenesis. We examined the expression levels of 7 types of $ELR^+$ CXCLs messenger RNA (mRNA) in 264 clinical samples. We found that CXCL2 expression was stably down-regulated in 94% of hepatocellular carcinoma (HCC) specimens compared with paired adjacent normal liver tissues and some HCC cell lines. Moreover, CXCL2 overexpression profoundly attenuated HCC cell proliferation and growth and induced apoptosis in vitro. In animal studies, we found that overexpressing CXCL2 by lentivirus also apparently inhibited the size and weight of subcutaneous tumours in nude mice. Furthermore, we demonstrated that CXCL2 induced HCC cell apoptosis via both nuclear and mitochondrial apoptosis pathways. Our results indicate that CXCL2 negatively regulates the cell cycle in HCC cells via the ERK1/2 signalling pathway. These results provide new insights into HCC and may ultimately lead to the discovery of innovative therapeutic approaches of HCC.

• Journal of the Korean Geotechnical Society
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• v.18 no.4
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• pp.271-283
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• 2002

P-wave velocity of concrete is a crucial parameter in determining the thickness of concrete lining, the location of cracks or other defects in Impact-Echo(IE) method. This study introduces an IE-SASW method that may determine the P-wave velocity on a surface of each testing area using the Spectral Analysis of Surface Wave (SASW) method. In numerical studies(Part I), it was verified that P-wave velocities could be obtained from SASW. In this paper(Part II), experimental studies were made in slab type concrete model specimens in which voids and waterproof sheet were included at the known locations. Accordingly, the feasibility of the proposed method was evaluated. The IE-SASW method was also performed in the precast model tunnel on ground and open-cut tunnel in ground. SASW tests were performed to determine the P-wave velocity of the concrete and then IE tests were carried at regularly spaced points along the testing lines to determine the thickness of structures. The nondestructive testing method which combined SASW and IE tests showed the great potential in the field applications.

• Restorative Dentistry and Endodontics
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• v.25 no.4
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• pp.606-618
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• 2000

Dental pulp infection is most commonly caused by extensive dental caries, and some bacterial species invade root canals; bacterial components and products are thought to be associated with the pathogenesis of periapical periodontitis. A principle driving force behind pulpal disease response appears to lie in the host immune system's to bacteria and their products. We examined the production of interleukin $1{\beta}$ (IL-$1{\beta}$) and tumor necrosis factor ${\alpha}$(TNF-${\alpha}$) from human peripheral mononuclear cells, lymphocytes and monocytes stimulated by heat-killed Acitnobacillus actinomycetemcomitans (ATCC 29523), Porphyromonas gingivalis (ATCC 33277) and Prevotella intermedia (ATCC 25611), and also by their sonicated bacterial extracts (SBE), respectively. The effects of three strains of heat-killed bacteria and their SBEs on the morphology of cultured blood cell lines HL-60 (KCLB 10240) and J774A.1 (KCLB 40067) were observed under the inverted microscope. Ultrastructural changes of J774A.1 exposed to heat-killed P. intermedia and its SBE were investigated using transmission electron microscopy. Production of IL-$1{\beta}$ was reduced in human peripheral mononuclear cells after stimulation by sonic bacterial extracts of A. actinomycetemcomitans, P. gingivalis, and P. intermedia. Heat-killed and sonic extract of P. gingivalis inhibited the production of TNF-${\alpha}$ in peripheral mononuclear cells. Production of TNF-${\alpha}$ was inhibited in peripheral monocytes after stimulation by sonic extracts of A. actinomycetemcomitans, P. gingivalis, and P. intermedia. HL-60 and J 774A.1 cells showed granular degeneration after treatment with heat-killed and sonic extracts of A. actinomycetemcomitans, P. gingivalis, and P. intermedia Chromatin margination and shrinkage were observed in 774A.1 treated with heat-killed P. intermedia. Cell wall structure and organelles were destroyed and vacuoles were formed in cytoplasm in J774A.1 treated with P. intermedia sonic extract. These results suggest that A actinomycetemcomitans, P gingivalis and P intermedia may have an important role in the formation and progression of pulpal diseases via both modulation of production of IL-$1{\beta}$ and TNF-${\alpha}$ from blood mononuclear cells and cytopathic effects.

• Fashion & Textile Research Journal
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• v.8 no.2
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• pp.225-232
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• 2006

This study purposed to review the concept and characteristics of subculture theoretically and then to analyze subcultural hairstyles shown in the 20th century's fashion in terms of form, structure, texture, design line and design principle, which were formative factors of beauty art. The range of this study was from the 1950's to the 1990's, during which subcultural hairstyles, which were selected for this study, kept a unique formality as subcultural characteristics of each time were reflected in hairstyles. The hairstyles found in subcultural styles were reviewed as follows. From the formative analysis as the above, it was concluded that layer form was seen most frequently in the subcultural hairstyles. This may be because it has a lot of layers in hair, and enables to make more various forms with a simpler care than other hairstyles so that it is easy to show one's own characteristic or differentiate oneself from others. Thanks to the characteristics of layer form, horizontal and convex were often seen as design lines. As for a texture, straight often appeared. The texture of straight is naturally formed without any care applied on hair. The reason may be that most subcultures refused artificiality. Therefore, the characteristics of subcultural hairstyles may be that hairstyles are transformed into various forms and created into the styles appropriately for individual tastes so as to clearly express one's own idea and thought.