• 대한산업공학회지
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• 제34권3호
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• pp.362-372
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• 2008

Manufacturers, or vendors, and their customers continue to adopt vendor-managed inventory(VMI) program to improve supply chain performance through collaboration achieved by consolidating replenishment responsibility upstream with vendors. In this paper, we construct a mixed integer linear programming model and propose a genetic algorithm for the integrated inventory and routing problems with lost sales maximizing the total profit in the VMI supply chains which comprise of a single manufacturer and multi-retailer. The proposed GA is compared with the mathematical model on the various sized test problems with respect to the solution quality and computation time. As a result, the GA demonstrates the capability of reaching solutions that are very close to those obtained by the mathematical model for small problems and stay within 3.2% from those obtained by the mathematical model for larger problems, with a much shorter computation time. Finally, we investigate the effects of the cost and operation variables on the total profit of the problem as well as the GA performance through the sensitivity analyses.

• 한국통계학회:학술대회논문집
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• 한국통계학회 2000년도 추계학술발표회 논문집
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• pp.193-200
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• 2000

Modelling the dependence via random effects in censored multivariate survival data has recently received considerable attention in the biomedical literature. The random effects models model not only the conditional survival times but also the conditional hazard rate. Systematic likelihood inference for the models with random effects is possible using Lee and Nelder's (1996) hierarchical-likelihood (h-likelihood). The purpose of this presentation is to introduce Ha et al.'s (2000a,b) inferential methods for the random effects models via the h-likelihood, which provide a conceptually simple, numerically efficient and reliable inferential procedures.

• 응용통계연구
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• 제28권2호
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• pp.269-279
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• 2015

본 논문에서는 임의효과에 대한 추론 문제가 다루어졌으며 이 추론에서 신뢰분포를 사용하는 것이 제안되었다. 신뢰분포를 이용한 방법은 표본의 크기가 작아도 임의절편들이 있는 로지스틱 회귀분석에서 좋은 결과를 보여주었으며, 자료분석을 통해서도 각 개체가 가지는 임의효과들에 대한 세밀한 분석이 가능함을 확인하였다.

• Asian-Australasian Journal of Animal Sciences
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• 제21권6호
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• pp.784-788
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• 2008

Studies to detect genes responsible for economic traits in farm animals have been performed using parametric linear models. A non-parametric, model-free approach using the 'expanded multifactor-dimensionality reduction (MDR) method' considering high dimensionalities of interaction effects between multiple single nucleotide polymorphisms (SNPs), was applied to identify interaction effects of SNPs responsible for carcass traits in a Hanwoo beef cattle population. Data were obtained from the Hanwoo Improvement Center, National Agricultural Cooperation Federation, Korea, and comprised 299 steers from 16 paternal half-sib proven sires that were delivered in Namwon or Daegwanryong livestock testing stations between spring of 2002 and fall of 2003. For each steer at approximately 722 days of age, the Longssimus dorsi muscle area (LMA) was measured after slaughter. Three functional SNPs (19_1, 18_4, 28_2) near the microsatellite marker ILSTS035 on BTA6, around which the QTL for meat quality were previously detected, were assessed. Application of the expanded MDR method revealed the best model with an interaction effect between the SNPs 19_1 and 28_2, while only one main effect of SNP19_1 was statistically significant for LMA (p<0.01) under a general linear mixed model. Our results suggest that the expanded MDR method better identifies interaction effects between multiple genes that are related to polygenic traits, and that the method is an alternative to the current model choices to find associations of multiple functional SNPs and/or their interaction effects with economic traits in livestock populations.

• Communications for Statistical Applications and Methods
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• 제26권3호
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• pp.315-323
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• 2019

Panel data sets have recently been developed in various areas, and many recent studies have analyzed panel, or longitudinal data sets. Often a dichotomous dependent variable occur in survival analysis, biomedical and epidemiological studies that is analyzed by a generalized linear mixed effects model (GLMM). The most common estimation method for the binary panel data may be the maximum likelihood (ML). Many statistical packages provide ML estimates; however, the estimates are computed from numerically approximated likelihood function. For instance, R packages, pglm (Croissant, 2017) approximate the likelihood function by the Gauss-Hermite quadratures, while Rchoice (Sarrias, Journal of Statistical Software, 74, 1-31, 2016) use a Monte Carlo integration method for the approximation. As a result, it can be observed that different packages give different results because of different numerical computation methods. In this note, we discuss the pros and cons of numerical methods compared with the exact computation method.

• 자원ㆍ환경경제연구
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• 제26권2호
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• pp.173-203
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• 2017

본 연구는 2000~2013년까지 14년간 서울, 부산, 대구, 인천 4개 대도시에 대한 총 주행거리, 도로연장길이, 대중교통 이용객수, 지역내총생산, 지역인구, 석유류 소비량에 대한 횡단시계열자료를 활용하여 도로연장에 대한 반등효과가 우리나라에도 적용되는지를 실증분석하였다. 혼합효과모형으로 추정한 결과 도로연장은 총 주행거리와 동반상승관계에 있는 반면, 대중교통 이용량은 총 주행거리와 역관계에 있는 것으로 나타났다. 이는 도로연장을 중심으로 하는 공급관리형 교통정책이 도시 광역화로 자가운전의 편의성을 직접적으로 증진시키거나, "걷기 힘든" 환경조성을 통해 자가운전 외 교통수단 이용의 편의성을 절감시킴으로써 추가적인 도로이용을 유인함을 뜻한다. 즉, 교통혼잡 및 정체 개선을 위해서는 현재의 도로연장 중심의 정책보다는 대중교통의 편의성 증진을 골자로 하는 교통수요관리 정책에 맞추어야 함을 시사한다.

• 응용통계연구
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• 제28권2호
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• pp.335-342
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• 2015

경시적 자료는 각 환자마다 시간에 따라 반복 측정되는 코호트 연구 등에서 많이 쓰인다. 본 연구는 반응변수 간 상관성을 고려할 수 있는 결합 다단계 일반화 선형모형을 이용하여, 다변량 경시적 자료 분석을 수행하였다. 한국 유전체 역학 연구에서 실시한 코호트 자료를 적합하고 결과를 해석한다. 조건부 아카이케 정보 기준을 이용하여 모형 선택을 하고, 변량효과들의 추정치들을 설명한다.

• 보건행정학회지
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• 제33권3호
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• pp.295-310
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• 2023

Background: The long-term care (LTC) group has higher rates of chronic disease and disability registration compared to the general older people population. There is a need to provide integrated medical services and care for LTC group. Consequently, this study aimed to identify medical usage patterns based on the ratings of LTC and the characteristics of benefits usage in the LTC group. Methods: This study employed the National Health Insurance Service Database to analyze the effects of demographic and LTC-related characteristics on medical usage from 2015 to 2019 using a repeated measures analysis. A longitudinal logit model was applied to binary data, while a linear mixed model was utilized for continuous data. Results: In the case of LTC ratings, a positive correlation was observed with overall medical usage. In terms of LTC benefit usage characteristics, a higher overall level of medical usage was found in the group using home care benefits. Detailed analysis by medical institution classification revealed a maintained correlation between care ratings and the volume of medical usage. However, medical usage by classification varied based on the characteristics of LTC benefit usage. Conclusion: This study identified a complex interaction between LTC characteristics and medical usage. Predicting the requisite medical services based on the LTC rating presented a challenge. Consequently, it becomes essential for the LTC group to continuously monitor medical and care needs, even after admission into the LTC system. To facilitate this, it is crucial to devise an LTC rating system that accurately reflects medical needs and to broaden the implementation of integrated medical-care policies.

• 한국복합재료학회:학술대회논문집
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• 한국복합재료학회 2001년도 춘계학술발표대회 논문집
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• pp.147-150
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• 2001

In the present work, a linear static analysis is presented for thin-walled prismatic box-beams made of generally anisotropic materials. A mixed beam theory has been used to model and carry out the analysis. Three different constitutive relations are assessed into the beam formulation. Simple layup cases having symmetric or anti-symmetric configuration have been chosen and tested to clearly show the effects of elastic couplings of the beam. Both 2D and 3D finite element structural analysis using the MSC/NASTRAN has been performed to validate the current analytical results. Results show that appropriate assumptions for the constitutive equations are important and prerequisite for the accurate prediction of beam stiffness constants and also for the beam behavior.

• Communications for Statistical Applications and Methods
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• 제15권2호
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• pp.265-271
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• 2008

It is commonly believed that diseases of human or economic traits of livestock are caused not by single genes acting alone, but multiple genes interacting with one another. This issue is difficult due to the limitations of parametric-statistic methods of gene effects. So we introduce multifactor-dimensionality reduction(MDR) as a methods for reducing the dimensionality of multilocus information. The MDR method is nonparametric (i. e., no hypothesis about the value of a statistical parameter is made), model free (i. e., it assumes no particular inheritance model) and is directly applicable to case-control studies. Application of the MDR method revealed the best model with an interaction effect between the SNPs, SNP1 and SNP3, while only one main effect of SNP1 was statistically significant for LMA (p < 0.01) under a general linear mixed model.