• Korean Journal of Poultry Science
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• v.48 no.1
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• pp.41-50
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• 2021

Although feather-sexing using sex-linked genes related to feather development is a widely used chick sexing method in the poultry industry, the feather-sexing method has yet to be used for Korean native chickens (KNCs). The purpose of this study was to construct a KNC feather-sexing line using early-feathering (EF) and late-feathering (LF) genes for industrial application. Using 557 reddish-brown KNCs as the basal flock, frequencies of the EF (k) and LF (K) genes were estimated to be 0.814 and 0.186, respectively. This indicating that it would be feasible to construct a feather-sexing line using this chicken group, and we accordingly constructed EF paternal and LF maternal lines. On the basis of test-cross for the selection of LF homozygous (KK) males in the maternal line, we confirmed that three of 40 chickens were homozygous males. The survival rate, body weight, days at first egg-laying, hen-day egg production, and egg weight were analyzed to compare the production performance of EF and LF chickens. The results revealed that EF chickens were characterized by a superior survival rate, whereas LF chickens were superior in terms of egg production rate. However, no differences between LF and EF chickens were detected with respect to other production performance parameters. In addition, assessment of the fitness of sexed chicks produced in the established KNC feather-sexing lines revealed that the accuracy of sexing was 98.6%. Collectively, these findings indicate the feasibility of constructing effective KNC feather-sexing lines with potential industrial application.

• Toxicological Research
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• v.25 no.4
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• pp.189-193
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• 2009

Hypoxia inducible factor $1\alpha$ (HIF-$1\alpha$) is a potential marker of carcicnogenesis since it is overexpresssed in many human cancers such as brain, breast, and uterus, and its role has implicated in tumor cell growth and metastasis. In this study, we established a stable cell line that express green fluorescence protein (GFP)-fused hypoxia inducible factor $1\alpha$ (HIF-$1\alpha$) and evaluated the potential use of this cell line for assessment of carcinogenicity of chemical toxicants. Western blot analysis as well as fluorescence measurements showed that protein-level of GFP-HIF-$1\alpha$ was significantly enhanced in a dose-dependent manner upon treatment of hypoxia mimicking agents such as dexferrioxamine and $CoCl_2$. Well-Known tumor promoters such as mitomycin and methyl methanesulfonate. significantly induced the fluorescence intensity of GFP-HIF-$1\alpha$, whereas the known negative controls such as o-anthranilic acid and benzethonium chloride, did not. These results indicate that HIF-$1\alpha$ could be a biological parameter for detection of tumor initiators/promoters and suggest that the GFP-HIF-$1\alpha$ cell line is a useful system for screening of carcinogenic toxicants.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.33 no.2
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• pp.81-93
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• 2007

Purpose: Adenoid cystic carcinoma (ACC) is a relatively rare tumor that arises in glandular tissues of the head and neck region and sometimes has a protracted clinical course with perineural invasion and delayed onset of distant lung metastasis. Treatment failure of salivary ACC is most often associated with perineural and hematogenous tumor spread. However, very little has been known about the cellular and molecular mechanisms of perineural invasion and hematogenous distant metastasis of parotid ACC. This study was designed to develop an orthotopic tumor model of parotid adenoid cystic carcinoma in athymic nude mice. Experimental Design: A melanoma cell line was injected into the parotid gland of athymic mice to determine whether such implantation was technically feasible. A parotid ACC cell line was then injected into the parotid gland or the subcutaneous tissue of athymic mice at various concentrations of tumor cells, and the mice were thereafter followed for development of tumor nodule. The tumors were examined histopathologically for perineural invasion or regional or distant lung metastasis. We used an oral squmous cell carcinoma cell line as control. Results: Implantation of tumor(melanoma) cell suspension into the parotid gland of nude mice was technically feasible and resulted in the formation of parotid tumors. A parotid ACC cell line, ACC3 showed no significantly higher tumorigenicity, but showed significantly higher lung metastatic potential in the parotid gland than in the subcutis. In contrast, mucosal squmous cell carcinoma cell line doesn’t show significantly higher lung metastatic potential in the parotid gland than in the subcutis. The ACC tumor established in the parotid gland seemed to demonstrate perineural invasion of facial nerve, needs further study. Conclusion: An orthotopic tumor model of salivary ACC in athymic nude mice was successfully developed that closely recapitulates the clinical situations of human salivary ACC. This model should facilitate the understanding of the cellular and molecular mechanisms of tumorigenisis and metastasis of salivary ACC and aid in the development of targeted molecular therapies of salivary ACC.

• The Research Journal of the Costume Culture
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• v.5 no.3
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• pp.159-175
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• 1997

The purpose of the study is to analyze the pattern of human developmental growth with empirical anthropometric data for the establishment of the sizing system of junior high school student\`s uniforms. The sample size was 881 boys and 762 girls between age 12 and 14. An anthropometric database used for this study was the 1992 national anthropometric survey of Korea. The result obtained are as follows ; 1. Several items of anthropometric data on junior high school students students showed significant differences in accordance with age and sex. In the meantime, there was no difference on the item of height under the age of 12 between sex, however, significant difference on that age of 13 or over. The hip girth was the biggest growth rate among tyhe item of girth. The somatotype of boys is straight, while girls\` shows a curved line. The bodytype of girls shows slim waist, fat belly and hip girth. 2. The result of factor analysis indicated that the first factor was composed with girth, depth and width-measures, and the second factor of height, length-measures. The third factors were consisted of items of representing bodytype of trunk, and the fourth, bodytype of lower part of trunk. 3. The result of cluster analysis indicated that boys were sybdivided into 3 types and girls 4 types.

• Journal of the Korea Fashion and Costume Design Association
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• v.8 no.2
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• pp.171-182
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• 2006

The purpose of this study was to business cases of setting up a shopping mall for Hanbok and other successful marketing cases were investigated to seek easy ways of establishing a internet shopping mall and to provide information on the structure of e-market and online shopping malls. In our country, online market has overtaken offline one, and the former has made sustained progress. Many domestic Hanbok manufacturers set up their homepages as part of efforts for online marketing or P.R. However, online shopping malls are run just by a small number of companies, and traditional Hanbok manufacturers are in worst situations. To be steadily competitive enough to keep on attracting customers, they should try to make their way through e-market from diverse angels. The purpose of this study was to delve into the establishment of an online shopping mall for Hanbok products and relevant marketing in an attempt to lay the groundwork for solidifying the position of Hanbok products in apparel e-market.

• Fisheries and Aquatic Sciences
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• v.16 no.3
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• pp.177-185
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• 2013

The development of species-specific fish cell lines has become a valuable tool for biological research. In recent years, marine medaka Oryzias dancena has been recognized as a good experimental model fish but there are no reports of establishment of cell lines from this fish. In this study, two cell lines from O. dancena blastula embryos were established from 41 total trials (4.9%). The two cell lines displayed typical in vitro morphology and have been cultured for >121 passages, which corresponds to 293 days. The doubling times of the cell lines were 29.84 and 28.59 h, respectively, and both possessed the potential to expand in a clonal manner, albeit with significant differences between the two cell lines. The absence of any of the four main medium supplements; i.e., fish serum, fetal bovine serum, basic fibroblast growth factor, and medaka embryo extract, significantly inhibited growth. The proportion of cells possessing normal chromosome number was 45% and 46.7% of the cell lines, respectively. Taken together, two cell lines that proliferate continuously were established from marine medaka and these cell lines may provide a basic tool for characterizing the unique features of this fish species.

• Journal of the military operations research society of Korea
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• v.16 no.2
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• pp.14-28
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• 1990

The objective of this study is to propose how to acquire through international cooperation the sensitive nuclear technology, so called reprocessing technology. In spite of the need to reuse spent fuel, the transfer of the sensitive technology has been tightly controlled by the nuclear advanced countries due to the fear of nuclear proliferation and, in fact, it would be impossible to secure it by the economic means. In this regard, as a means of acquiring the sensitive nuclear technology, this study proposes the following; 1) President's declaration concerning the peaceful uses of nuclear energy, 2) the establishment and maintenance of national basis through inter-ministerial cooperation, 3) as a confidence building measure, the efforts to strengthen our role in the international nuclear community, and 4) the establishment of the synthetic feedback system to efficiently coordinate. In line with those stated above, this study suggests that it be necessary to invest consistently for developing new technologies and cultivating human resources. Furthermore, this study proposes the necessity to resolve the problems lying ahead by the national consensus achieved through the discussions among the public concerning the sensitive nuclear technology.

• KDI Journal of Economic Policy
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• v.40 no.4
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• pp.23-45
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• 2018

The Korean government has provided various policy devices to boost technology transfers between academia and industry since the establishment of the Technology Transfer Promotion Act in 2000. Along with the enactment of the law, the Korean government mandated the establishment of a technology transfer office at national and public universities and encouraged technology transfer activities. Despite the quantitative expansion of technology transfer offices (TTOs), operational inefficiency was brought up. As a supplementary policy, the Korean government implemented a line of projects to support the labor and business expenses of leading TTOs. This research questions whether the project greatly affected the technical efficiency of TTOs. We analyze publicly available university panel data from 2007 to 2015 using a one-step stochastic frontier analysis. The results suggest that the program was marginally effective at shifting the technical efficiency distribution to the right on average, but it failed to maximize its impact by diversifying the policy means based on targets. The marginal effects of the program on technical efficiency differ according to the research capability and size of each school. We also compare technical efficiency against the licensing income at the start and end of the program. Technical efficiency increased for the leading TTOs, and both measures show improvements for unsupported TTOs. Our empirical results imply that diversifying the program for universities with different characteristics may have improved the effectiveness of the policy.

• Korea Trade Review
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• v.44 no.2
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• pp.63-82
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• 2019

Due to technological development in the globalized food system, quantitative problems of food supply have been solved, but food risks have expanded from problems in specific regions to global problems. In order to maximize the efficiency of agricultural production, the growth in agricultural production system, procirement of raw materials, establishment of food processing processes and establishment of food supply chain systems are required. Control of hazards requires facility and administrative efforts. In this study, we examined the role of CSR in conjunction with food safety. Food SCM is related to food safety and correlates with the food supply chain. In terms of the triple bottom line theory, CSR is correlated with SCM and it is possible to pursue food safety through corporate CSR and SCM. In this study, it is statistically confirmed that SCM and CSR are in a positive relationship. In the impact of CSR on food safety, it has been confirmed that economic responsibility and legal responsibility take precedence over environmental responsibility and social responsibility. Based on this, we can achieve food safety through SCM and CSR, and we can decide which of CSR activities can be prioritized.

• Journal of the Society of Disaster Information
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• v.16 no.4
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• pp.784-795
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• 2020

Purpose: This study intends to review the risk assessment procedures specified in the corporate disaster management standard. Method: The requirements for each stage of risk assessment stipulated in the corporate disaster management standard were identified, the case of application of the organization'A' and the partner companies were reviewed, and the risk assessment procedure in line with the requirements was reviewed. Result: It was reviewed that it was necessary to clearly define the method and procedure for deriving risk scenarios, which are the requirements of the corporate disaster management standard, and to introduce a standardized procedure for deriving risk scenarios. Conclusion: A method of deriving risk scenarios was implemented by applying the STPA technique based on the system theory for power generation fuel supply and demand, and it was suggested that the STPA technique be reflected in corporate disaster management standards as a risk scenario derivation technique for the establishment of a disaster reduction activity plan.