• Title/Summary/Keyword: lifespan

Search Result 552, Processing Time 0.021 seconds

Kinetic analysis of E. coli disinfection using UV-LED (LED 광원 UV에 의한 대장균(E. coli) 소독의 속도론 해석)

  • Kim, Kyeong-Rae;Chang, In-Soung
    • Journal of Korean Society of Water and Wastewater
    • /
    • v.35 no.6
    • /
    • pp.489-496
    • /
    • 2021
  • Water disinfection using UV-LED(Light emitting diode) has many advantages, such as smaller footprint and power consumption as well as relatively longer lifespan than those of conventional mercury-UV lamps. Moreover, UV-LED disinfection is considered an environmentally benign process due to its mercury-free nature. In this study, disinfection using an LED module emitting 275nm UV was carried out. 384 UV-LEDs were put into a cylinder tube with a capacity of 1.7 liters. The UV intensity of the UV-LED module was controlled from 1.7 to 8.4 mW/cm2. The disinfection efficiency for the model microorganism solutions(E. coli ) was monitored. As the UV intensity(I) and contact time(t) varied, inactivation of the microorganisms from 2 to 4-log-removals(i.e., 99 to 99.99% of disinfection efficiency) was achieved. Disinfection using UV-LED was followed to 1st order reaction and the reaction rate constant, k was determined. In addition, the relationship between UV intensity(I) and contact time(t) in order to obtain 99.99% of disinfection efficiency was modeled: I1.2·t= 460, which indicates that the product of UV intensity and contact time requiring 4-log-removals is always constant.

Notification of Terminal Status and Advance Care Planning in Patients with Cancer

  • Lee, Si Won
    • Journal of Hospice and Palliative Care
    • /
    • v.25 no.1
    • /
    • pp.42-49
    • /
    • 2022
  • As population aging increases the burden of cancer, the quality of death of patients with cancer is emerging as an important issue alongside their quality of life. To improve the quality of death, it is necessary to prepare for death, allowing patients to die comfortably and with dignity at the end. Considering these issues, I aim to discuss the practical aspects of notifying the patient of the terminal phase of cancer and planning for end-of-life care (i.e., advance care planning). When cancer treatment that can extend the patent's lifespan becomes difficult, the patient enters a treatment transition period. Treatment is shifted from life-prolonging care to life-enhancing care, and end-of-life care must be well planned. Medical providers often worry too much about whether the patient will be disappointed or psychologically traumatized when notified of the terminal phase of their cancer, thus delaying plans for end-of-life care. In fact, patients can accept their condition and prepare for end-of-life care better than we expect. During the treatment transition period, notification of terminal status should be given, and a well-prepared advance care plan should be established early when the patient has decision-making ability. In addition to conveying information, it is always necessary to be sensitive to whether the patient and caregiver understand the information and respond to their emotions.

Mechanical Behavior of Treated Timber Boardwalk Decks under Cyclic Moisture Changes

  • LIU, Jian;JI, Yiling;LU, Jiaming;LI, Zhi
    • Journal of the Korean Wood Science and Technology
    • /
    • v.50 no.1
    • /
    • pp.68-80
    • /
    • 2022
  • Timber boardwalk decks are widely installed in parks and scenic areas to provide pedestrians an elevated footpath as well as harmony with the surrounding natural scene. In order to extend the lifespan of boardwalks in the outdoor environment, industrially treated pine timber, such as Pinus sylvestris, is often adopted. However, accidents of pedestrians injured by damaged boardwalk decks have been constantly reported. Therefore, the mechanical behavior of two different types of treated timber was examined in this study under repeated wetting and drying. An increasing number of radial cracks appeared with increasing length and width as more cycles were performed. A loss of more than 40% of the screw withdrawal capacity was observed in both end grain and face grain for the two types of timber after twelve accelerated wet-dry cycles, which coincides with the observation of damaged timber boardwalks in the field investigation. At the same time, it was found that both the compressive and the flexural strength was not sensitive to the wet-dry cycles especially at large cycle numbers.

Shape Design of Shearing Die for the Chassis Part with the Coupled Analysis of Shear and Die Structure (전단-구조연계해석을 이용한 섀시부품 전단금형의 형상설계)

  • Kim, S.H.
    • Transactions of Materials Processing
    • /
    • v.31 no.5
    • /
    • pp.261-266
    • /
    • 2022
  • To reduce the weight of the vehicle, the application of the high strength steel sheets to chassis parts is increased. High forming load is induced during the shearing process of steel chassis parts made of high strength steel, and the possibility of an eccentric load is increased depending on the product seating condition on the die, which decreases the stability and lifespan of the die. In this paper, a three-dimensional finite element analysis with the continuum element was conducted using the damage theory for the cam-trimming process of the front lower arm. The structural analysis of the trimming die was performed with the forming load result obtained from the analysis, and the amount of deflection and the stress distribution of the die during the shearing process were evaluated for the confirmation of the tool stability. The shape of the weak region of the die was modified according to structural analysis and then the stability was confirmed with the finite element analysis. The analysis result showed that the possibility of tool failure during cam-trimming process was remarkably reduced, and the reliability of the proposed modified design was validated.

Comparison of punch life of powder high speed tool steel and high speed tool steel (분말고속도공구강과 고속도공구강의 펀치 수명 비교)

  • Lee, Woo-Ram;Lee, Chun-Kyu
    • Design & Manufacturing
    • /
    • v.16 no.1
    • /
    • pp.9-14
    • /
    • 2022
  • A lot of research is being done on metal materials to improve the lifespan of molded parts. As a result, excellent mold materials have been developed that withstand high hardness at high temperatures and frictional heat generated from high-speed cutting. In this study, the press mold life of powder high-speed tool steel and general high-speed tool steel was compared. Powdered high-speed steel is composed of alloying elements such as tungsten, maldividene, cobalt, chromium, and vanadium in steel, which improves wear resistance compared to high-hardness and high-speed tool steels. The mold parts of both steel types were manufactured in the same way from heat treatment to machining, and the powder high-speed tool steel was 66HRC and the high-speed tool steel was 61HRC. As a result of the experiment, it was observed that the number of punching of powder high-speed tool steel was improved by 40-50%, and powder high-speed tool steel had fewer impurities, uniform texture, and excellent surface structure. It has a microscopic structure.

Optimizing Garbage Collection Overhead of Host-level Flash Translation Layer for Journaling Filesystems

  • Son, Sehee;Ahn, Sungyong
    • International Journal of Internet, Broadcasting and Communication
    • /
    • v.13 no.2
    • /
    • pp.27-35
    • /
    • 2021
  • NAND flash memory-based SSD needs an internal software, Flash Translation Layer(FTL) to provide traditional block device interface to the host because of its physical constraints, such as erase-before-write and large erase block. However, because useful host-side information cannot be delivered to FTL through the narrow block device interface, SSDs suffer from a variety of problems such as increasing garbage collection overhead, large tail-latency, and unpredictable I/O latency. Otherwise, the new type of SSD, open-channel SSD exposes the internal structure of SSD to the host so that underlying NAND flash memory can be managed directly by the host-level FTL. Especially, I/O data classification by using host-side information can achieve the reduction of garbage collection overhead. In this paper, we propose a new scheme to reduce garbage collection overhead of open-channel SSD by separating the journal from other file data for the journaling filesystem. Because journal has different lifespan with other file data, the Write Amplification Factor (WAF) caused by garbage collection can be reduced. The proposed scheme is implemented by modifying the host-level FTL of Linux and evaluated with both Fio and Filebench. According to the experiment results, the proposed scheme improves I/O performance by 46%~50% while reducing the WAF of open-channel SSDs by more than 33% compared to the previous one.

Mold-design Verification of Ball Housing Insert Die in Non Processing Type Multi-stage Cold Forging (다단냉간단조 비가공 타입에서 볼하우징 인서트 다이의 금형설계 검증)

  • Hwang, Won-Seok;Choi, Jong-Won;Jung, Eu-Enn;Kang, Myungchang
    • Journal of the Korean Society of Manufacturing Process Engineers
    • /
    • v.20 no.12
    • /
    • pp.8-15
    • /
    • 2021
  • Cold forging is a method in which molding is performed at room temperature. It has a high material recovery rate and dimensional precision and produces excellent surface quality, and it is mainly used for the production of bolted or housing products. The lifespan of cold forging molds is generally determined by the wear of the mold, plastic deformation of the mold, and fatigue strength. Cold forging molds are frequently damaged due to fatigue destruction rather than wear and plastic deformation in a high-temperature environment as it is molded at room temperature without preheating the raw material and mold. Based on the results analyzed through FEM, an effective mold structure design method was proposed by analyzing the changes in tensile and compressive stresses on molds according to the number of molds and reinforcement rings and comparing the product geometry and mold stress using three existing mold models.

Life Prediction of Hydraulic Concrete Based on Grey Residual Markov Model

  • Gong, Li;Gong, Xuelei;Liang, Ying;Zhang, Bingzong;Yang, Yiqun
    • Journal of Information Processing Systems
    • /
    • v.18 no.4
    • /
    • pp.457-469
    • /
    • 2022
  • Hydraulic concrete buildings in the northwest of China are often subject to the combined effects of low-temperature frost damage, during drying and wetting cycles, and salt erosion, so the study of concrete deterioration prediction is of major importance. The prediction model of the relative dynamic elastic modulus (RDEM) of four different kinds of modified concrete under the special environment in the northwest of China was established using Grey residual Markov theory. Based on the available test data, modified values of the dynamic elastic modulus were obtained based on the Grey GM(1,1) model and the residual GM(1,1) model, combined with the Markov sign correction, and the dynamic elastic modulus of concrete was predicted. The computational analysis showed that the maximum relative error of the corrected dynamic elastic modulus was significantly reduced, from 1.599% to 0.270% for the BS2 group. The analysis error showed that the model was more adjusted to the concrete mixed with fly ash and mineral powder, and its calculation error was significantly lower than that of the rest of the groups. The analysis of the data for each group proved that the model could predict the loss of dynamic elastic modulus of the deterioration of the concrete effectively, as well as the number of cycles when the concrete reached the damaged state.

Emerging roles of neutrophils in immune homeostasis

  • Lee, Mingyu;Lee, Suh Yeon;Bae, Yoe-Sik
    • BMB Reports
    • /
    • v.55 no.10
    • /
    • pp.473-480
    • /
    • 2022
  • Neutrophils, the most abundant innate immune cells, play essential roles in the innate immune system. As key innate immune cells, neutrophils detect intrusion of pathogens and initiate immune cascades with their functions; swarming (arresting), cytokine production, degranulation, phagocytosis, and projection of neutrophil extracellular trap. Because of their short lifespan and consumption during immune response, neutrophils need to be generated consistently, and generation of newborn neutrophils (granulopoiesis) should fulfill the environmental/systemic demands for training in cases of infection. Accumulating evidence suggests that neutrophils also play important roles in the regulation of adaptive immunity. Neutrophil-mediated immune responses end with apoptosis of the cells, and proper phagocytosis of the apoptotic body (efferocytosis) is crucial for initial and post resolution by producing tolerogenic innate/adaptive immune cells. However, inflammatory cues can impair these cascades, resulting in systemic immune activation; necrotic/pyroptotic neutrophil bodies can aggravate the excessive inflammation, increasing inflammatory macrophage and dendritic cell activation and subsequent TH1/TH17 responses contributing to the regulation of the pathogenesis of autoimmune disease. In this review, we briefly introduce recent studies of neutrophil function as players of immune response.

Application of nanoparticles in extending the life of oil and gas transmission pipeline

  • Yunye, Liu;Hai, Zhu;Jianfeng, Niu
    • Structural Engineering and Mechanics
    • /
    • v.84 no.6
    • /
    • pp.733-741
    • /
    • 2022
  • The amount of natural gas that is used on a worldwide scale is continuously going up. Natural gas and acidic components, such as hydrogen sulfide and carbon dioxide, cause significant corrosion damage to transmission lines and equipment in various quantities. One of the fundamental processes in natural gas processing is the separation of acid gases, among which the safety and environmental needs due to the high toxicity of hydrogen sulfide and also to prevent wear and corrosion of pipelines and gas transmission and distribution equipment, the necessity of sulfide separation Hydrogen is more essential than carbon dioxide and other compounds. Given this problem's significance, this endeavor aims to extend the lifespan of the transmission lines' pipes for gas and oil. Zinc oxide nanoparticles made from the environmentally friendly source of Allium scabriscapum have been employed to accomplish this crucial purpose. This is a simple, safe and cheap synthesis method compared to other methods, especially chemical methods. The formation of zinc oxide nanoparticles was shown by forming an absorption peak at a wavelength of about 355 nm using a spectrophotometric device and an X-ray diffraction pattern. The size and morphology of synthesized nanoparticles were determined by scanning and transmission electron microscope, and the range of size changes of nanoparticles was determined by dynamic light scattering device.