• The Korean Journal of Physiology and Pharmacology
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• 제25권4호
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• pp.281-296
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• 2021

The beneficial effects of hypoxic preconditioning are abolished in the diabetes. The present study was designed to investigate the protective effects and mechanisms of repeated episodes of whole body hypoxic preconditioning (WBHP) in db/db mice. The protective effects of preconditioning were explored on diabetes-induced vascular dysfunction, cognitive impairment and ischemia-reperfusion (IR)-induced increase in myocardial injury. Sixteen-week old db/db (diabetic) and C57BL/6 (non-diabetic) mice were employed. There was a significant impairment in cognitive function (Morris Water Maze test), endothelial function (acetylcholine-induced relaxation in aortic rings) and a significant increase in IR-induced heart injury (Langendorff apparatus) in db/db mice. WBHP stimulus was given by exposing mice to four alternate cycles of low (8%) and normal air O₂ for 10 min each. A single episode of WBHP failed to produce protection; however, two and three episodes of WBHP significantly produced beneficial effects on the heart, brain and blood vessels. There was a significant increase in the levels of brain-derived neurotrophic factor (BDNF) and nitric oxide (NO) in response to 3 episodes of WBHP. Moreover, pretreatment with the BDNF receptor, TrkB antagonist (ANA-12) and NO synthase inhibitor (L-NAME) attenuated the protective effects imparted by three episodes of WBHP. These pharmacological agents abolished WBHP-induced restoration of p-GSK-3β/GSK-3β ratio and Nrf2 levels in IR-subjected hearts. It is concluded that repeated episodes of WHBP attenuate cognitive impairment, vascular dysfunction and enhancement in IR-induced myocardial injury in diabetic mice be due to increase in NO and BDNF levels that may eventually activate GSK-3β and Nrf2 signaling pathway to confer protection.

• 한국교육논총
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• 제38권1호
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• pp.61-77
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• 2017

본 논문은 국사편찬위원회의 "한민족독립운동사자료집" 3.1운동편을 통해, 신문조서에 드러난 학생과 농민들의 진술에 드러나는 특징을 포착하려 하였다. 국사편찬위원회 신문조서에 어떤 사람들이 조사를 받았는지를 우선 확인하였다. 이를 통해 주로 경성의 학생, 경기도의 농민들이 조사받은 기록이 남아있음을 확인할 수 있었다. 그 다음 그들이 3.1운동에 참여한 이유는 무엇이었는지 추적하였다. 신문조서에서 말한 불만사항들을 정리하고, 그러한 불만이 '독립'과 어떻게 연결되는가를 확인하였다. 이를 통해 학생들은 주로 교육에 관심을 가지고 있었으며 자신들의 불만을 명확하게 표현하였던 데 비하여, 농민들은 총독정치 하에서의 생활 및 세금 문제에 불만을 품고 있었고, 스스로의 불만을 명확히 표현하지 못하였다는 것을 확인하였다. 그 중에서도 처벌을 경감받고자 하는 태도를 뛰어 넘어, 불만은 없지만 독립은 필요하다는 방식의 사고를 하는 조선인들이 확인된다. 이들은 우선 독립 만세를 외친 이후에 감옥에서 독립의 의미를 깨닫기도 하였다. 3.1운동의 의미는 행위 이후에 사후적으로 의미가 부여되기도 하였던 것이다.

• 한국산학기술학회논문지
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• 제22권2호
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• pp.755-765
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• 2021

본 연구는 1945년부터 1954년까지의 해방세대와 그 이후 세대인 1955년부터 1963년까지의 베이비붐세대로 노인인구집단을 세분한 후 이 두 세대 집단 간 사회적 자본(신뢰, 참여, 네트워크, 규범 및 호혜성)과 안녕감에 있어 평균차이가 있는지 검증하고, 사회적 자본이 안녕감에 미치는 영향을 검증한 후 사회적 자본의 하위요인별 안녕감에 미치는 영향관계 및 영향력에 있어 두 세대 집단 간 차이가 있는지 검토하는 데 목적이 있다. 이를 위해 2018년 7월 1일부터 7월 31일까지 D지역에서 200명의 자료를 수집해 최종 분석하였다. 본 연구의 주요 결과는 다음과 같다. 첫째, 사회적 자본의 하위변수 중 신뢰와 참여, 그리고 종속변수인 안녕감은 두 세대 간 유의한 평균 차이가 있는 것으로 나타났다. 둘째, 사회적 자본의 하위변수 중 네트워크만이 안녕감에 정적 영향을 미치는 것으로 나타났다. 셋째, 사회적 자본의 하위변수 중 신뢰가 안녕감에 정적 영향을 미치는 것으로 나타났다. 넷째, 해방세대와 베이비붐세대, 각 집단의 안녕감에 영향을 미치는 사회적 자본을 비교·검토한 결과 통계적 유의수준을 90% 수준으로 완화해 살피자면 네트워크는 두 집단에 공히 영향을 미치는 변수로 작동함을 알 수 있는데, 이 경우 회귀계수의 영향력을 ��값으로 상호 비교하면 네트워크는 해방세대의 안녕감에 상대적으로 더 큰 영향을 미치는 것으로 나타났다. 이상의 결과를 토대로 이들 노인집단에 대한 사회복지 서비스 및 프로그램 구안에 관한 정책적·실무적 제언을 하였다.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 1999년도 학회창립 10주년 기념 1999년도 가을 학술발표회 논문집
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• pp.289-292
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• 1999

The charateristic of hydration reaction was studied in CaO-Al2O3-SiO2 system glass. As a result, the rate of heat liberation curves of synthestized glass becomes fixed after having increased by degrees. And it is decreasing after having increased suddenly. It was found that the total heat liberation with hydration for synthesized glass has a close relationship with the formation amount of ettringite.

• 한국세라믹학회지
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• 제27권2호
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• pp.149-154
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• 1990

Before benefication of Okchun feldspar, all kinds of Fe-compounds and mafic minerals which were included in feldspar were studied. Also to produce 30/140mesh products as glass materials, optimum grinding condition and degree of liberation were studied. Fe-compounds were Biotite and Limonite, and these were existed along the cleavage. Optimum grinding time was 2min. and at this time weight percent of 30/140mesh products was 72.7% and degree of liberation at this particle size was 91.5%.

• Asian Pacific Journal of Cancer Prevention
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• 제13권1호
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• pp.191-194
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• 2012

We conducted a case-control study in China to clarify the association between XRCC1-Arg399Gln polymorphism and HCC risk. A total of 150 cases and 158 controls were selected from the the Affiliated Hospital of Qingdao University from May 2008 to May 2010. XRCC1-Arg399Gln polymorphism was based upon duplex polymerase-chain-reaction with the confronting-two-pairprimer (PCR-CTPP) method. All analyses were performed using the STATA statistical package. A significantly increased risk was associated with the Arg/Gln genotype (adjusted OR 1.78, 95%CI=1.13-2.79) compared with genotype Arg/Arg. In contrast, the Gln/Gln genotype had non-significant increased risk of HCC with adjusted OR (95%CI) of 1.69 (0.93-2.66). A significant association was found between positive HBsAg and Arg/Gln, with an OR of 3.43 (95% CI=1.45-8.13). Patients carrying Gln/Gln genotypes showed significantly lower median survival than Arg/Arg genotypes (HR=1.38, 95% CI=1.04-1.84). Further Kaplan-Meier analysis showed decreased median survival in Arg/Gln+Gln/Gln genotype carriers in comparison to Arg/Arg carriers (HR=1.33, 95% CI=1.02-1.76). In conclusion, we observed that XRCC1-Arg399Cln polymorphism is associated with susceptibility to HCC, and XRCC1 Gln allele genotype showed significant prognostic associations.

• 전자공학회논문지CI
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• 제47권2호
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• pp.29-38
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• 2010

NVR은 시스템을 구성하는 모든 카메라와 비디오 서버가 네트워크 환경으로 연결되어 설치가 용이하며 유지 및 보수의 효율성이 뛰어나 차세대 영상 감시 시스템으로 각광받고 있다. 또한 사용자가 웹 기반으로 카메라, 비디오 서버에 접근 할 수 있어 시간적, 공간적 제한을 극복한 관리환경을 제공한다. 하지만 기존의 NVR 저장장치는 데이터가 손상될 경우, 이를 복구할 방법과 실시간으로 시스템을 유지할 수 있는 수단이 부족하다. 본 논문에서는 데이터의 손상 복구 및 실시간성 유지가 가능한 RSPM(Reliable Storage using Parity and Mirroring)기법을 제안한다. RSPM기법은 패리티 코드와 Liberation 코드 기법을 적용하여 영상 데이터의 손상을 복구할 수 있으며 동적 미러링 기법을 적용하여 시스템 데이터의 손상 복구 및 실시간성을 유지할 수 있다. 실험을 통해 Liberation 코드를 이용한 RSPM 기법이 EXT3 파일 시스템보다 영상 데이터 손상에 대한 손실율이 평균 약 11.29%의 감소됨을 알 수 있으며 패리티 코드를 적용한 RSPM 기법 보다 약 5.21% 감소됨을 알 수 있다.

• 한국의상디자인학회지
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• 제6권3호
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• pp.153-167
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• 2004

Korea had suffered the colony of Japanese imperialism and the Korean War from the invasion of the external circumstances. Such special situation made new influences on the clothing habits. The types of Korean women clothing could escape from the traditional style that had been maintained for thousands of years. The foreign clothes for Korean women had undergone various changes from the Liberation in 1945. The jackets that had been introduced to Korea at the Enlightenment period had become popular outfits for men. The jackets made big influences on the changes such as the social advances for women from the times background of the Liberation. The jackets possess very important meaning for the changes in the diffusion of feminism and fashion. Therefore, this research tries to investigate the forms, silhouettes, changes and structures of the jackets such as the locations of the collar, the sleeve, and the waste line. The process of the changes in the style of women jackets is also analyzed from the silhouette and the structure method. The development and changes will be understood of Korean women's jackets. The Korean women's jackets should also be examined further with the history of foreign clothing from now on. The fashion to be introduced from important society cultural phenomena and the Western Europe has been reflected into the changes in the style of Korean female jackets. Also, dramatic changes in the style of clothing indicate that the society had experienced a great deal of changes. It is verified that foreign clothes have been interacted with the stream of times worldwide. After the Liberation, the female jackets become a uniform style which just followed the Western European style. However, a season trend has been announced from the SFAA since 1990. Since then trendy jackets have been detailed more with this chance.

• 가족자원경영과 정책
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• 제21권1호
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• pp.19-44
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• 2017

The intergenerational transfer between parents and children is a major concern due to low birth rates and aging society of Korea. This study investigated the influences of children's support for parent regarding parents' decision to bequest, including the influences of parental characteristics, household-related factors, and characteristics of children. The data are the 5th wave of KReIS, a sample of 1,834 married household heads(HHs), which were classified into 142 baby boomers (1955-1963), 534 post-liberation HHs (1945-1954), and 1,158 Japanese-era HHs (-1945). The results were as follows: First, 49.3% of baby boomer HHs, 59.2% of post-liberation HHs, and 59.1% of Japanese-era HHs, were willing to make bequest decision. Second, in the baby boomer HHs, although the children's contact with their parents represented an emotional resource transfer, a child's economic resource transfer to his/her parents did not affect the parents' bequest decisions. However, in the post- liberation HHs, children's contact with parents, and economic resource transfers were significant variables. In addition, in the Japanese-era HHs, only children's contact with their parents was a significant variable. Third, in the baby boomer HHs, the variables that influenced parents' bequest decisions were household financial assets and having a daughter rather than having son and daughter. However, the variables that heavily influenced bequest decisions of the post-liberation HHs were the presence of a spouse, home ownership, household expenditures, and satisfaction of relationships with children. In the Japanese-era HHs, the variables that significantly affected parents' bequest decisions were home ownership, household expenditures, and household financial assets.

• Acute and Critical Care
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• 제33권4호
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• pp.260-268
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• 2018

Background: The purpose of this study was to evaluate the clinical application of modified Burns Wean Assessment Program (m-BWAP) scoring at first spontaneous breathing trial (SBT) as a predictor of successful liberation from mechanical ventilation (MV) in patients with endotracheal intubation. Methods: Patients requiring MV for more than 72 hours and undergoing more than one SBT in a medical intensive care unit (ICU) were prospectively enrolled over a 3-year period. The m-BWAP score at first SBT was obtained by a critical care nursing practitioner. Results: A total of 103 subjects were included in this study. Their median age was 69 years (range, 22 to 87 years) and 72 subjects (69.9%) were male. The median duration from admission to first SBT was 5 days (range, 3 to 26 days), and the rate of final successful liberation from MV was 84.5% (n=87). In the total group of patients, the successful liberation from MV group at first SBT (n=65) had significantly higher m-BWAP scores than did the unsuccessful group (median, 60; range, 43 to 80 vs. median, 53; range, 33 to 70; P<0.001). Also, the area under the m-BWAP curve for predicting successful liberation of MV was 0.748 (95% confidence interval, 0.650 to 0.847), while the cutoff value based on Youden's index was 53 (sensitivity, 76%; specificity, 64%). Conclusions: The present data show that the m-BWAP score represents a good predictor of weaning success in patients with an endotracheal tube in place at first SBT.