• Proceedings of the SAREK Conference
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• 2003.07a
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• pp.48-48
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• 2003

• 한국정보디스플레이학회:학술대회논문집
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• 2008.10a
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• pp.197-200
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• 2008

We propose a novel n-type a-Si:H TFT pixel circuit which is proper to AMOLED display for the large size and high resolution. Proposed pixel circuit will be suit to panel for the high resolution because of different threshold sampling method. Driving method of proposed pixel circuit is very simple like an AMLCD. Our simulation indicates that the proposed pixel circuit can compensate the Vth shift and IR rising of power line so that provide better quality image.

• YAKHAK HOEJI
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• v.40 no.1
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• pp.95-101
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• 1996

The in vitro antibacterial activities of LB10522, a new catechol-substituted cephalosporin, were compared with those of cefpirome, ceftazidime, ceftriaxone, and cefoperaz one against clinical isolates and laboratory standard anaerobes. LB10522 had broad spectrum antibacterial activities against both gram-positive and gram-negative microorganisms. It was most active against gram-positve bacteria among the reference cephalosporins tested. Against gram-negative strains such as the family Enterobacteriaceae, LB10522 showed an activity comparable to that of cefpirome. But LB10522 was more potent than ceftazidime, ceftriaxone and cefoperazone. In particular, Pseudomonas aeruginosa was highly susceptible to LB10522, which was 32-fold and 64-fold more active than ceftazidime and cefpirome, respectively. Against anaerobic strains, the activity of LB10522 was similar to those of reference compounds. LB10522 exhibited potent therapeutic activities against experimental local infections in mice. The therapeutic effect of LB10522 against urinary tract infection (UTI) caused by P. aeruginosa 1912E in mice was superior to that of cefpirome. Against experimental respiratory tract infection (RTI) caused by K. pneumoniae DT-S in mice, LB10522 was as effective as cefpirome. The in vivo efficacy of LB10522 was correlated well with its in vitro activity.

• YAKHAK HOEJI
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• v.40 no.1
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• pp.102-111
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• 1996

LB10522 is a new parenteral broad spectrum cephalosporin with a catechol moiety at C-7 position of beta-lactam ring. This compound can utilize tonB-dependent iron transp ort system in addition to porin proteins to enter bacterial periplasmic space and access to penicillin-binding proteins (PBPs) which are the lethal targets of ${\beta}$-lactam antibiotics. The chelating activity of LB10522 to metal iron was measured by spectrophotometrically scanning the absorbance from 200 to 900nm. When $FeCl_3$ was added, optical density was increased between 450 and 800nm. LB10522 was more active against gram-negative strains in iron-depleted media than in iron-replete media. This is due to the increased expression of iron transport channels in iron-depleted condition. LB10522 showed a similar activity against E. coli DC2 (permeability mutant) and E. coli DCO (wild type strain) in both iron-depleted and iron-replete media, indicating a minimal permeaility barrier for LB10522 uptake. LB10522 had high affinities to PBP 3 and PBP 1A, 1B of E. coli. By blocking these proteins, LB10522 caused inhibition of cell division and the eventual death of cells. This result was correlated well with the morphological changes in E. coli exposed to LB10522. Although the in vitro MIC of LB10522 against P. aeruginosa 1912E mutant (tonB) was 8-times higher than that of the P. aeruginosa 1912E parent strain, LB10522 showed a similar in vivo protection efficacy against both strains in the mouse systemic infection model. This result suggested that tonB mutant, which requires a high level of iron for normal growth, might have a difficulty in surviving in their host with an iron-limited environment.

• Biomolecules & Therapeutics
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• v.3 no.4
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• pp.322-326
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• 1995

General pharmacology of LB20304, a quinolone antibiotic, were examined in terms of general behaviour, cardiovascular, and central nervous system. LB20304 at oral dose of 2,000 mg/kg did not induce significant behavioural changes in mice. In contrast with ciprofloxacin, LB20304 at dose of 20 mg/kg, iv. did not show any observable effects on the blood pressure in rats. Displacement of [$^3$H]muscimol binding to the rat brain synaptic membranes was measured. LB20304 was shown to be about five times less potent than ciprofloxacin in specific GABA receptor binding. Drug interaction between LB20304 and 4-biphenyl acetic acid, an active metabolite of fenbufen, was assessed in mice by measuring convulsion and/or subsequent death. A single oral pretreatment with 4-BPA at 400 mg/kg increased the incidence of convulsion and death after oral administration of ciprofloxacin at the doses of 25, 50, and 100 from zero of five to three of five, two of five, and four of five, respectively, whereas LB20304 alone or combination with 4-BPA caused neither convulsions nor death at the doses of 12.5, 25, 50, and 100 mg/kg, respectively. Quinolones-induced epileptogenic activities were assessed by a direct intracerebral injection of test articles. The CD$_{50}$ values (nmole) are as follows; 169.47, 35.36, 105.29, and 88.67 for LB20304, ciprofloxacin, of loxacin, and lomefloxacin, respectively. From these data, LB 20304 at therapeutic doses seems to be much more safe than any other quinolones tested.d.

• Proceedings of the KIEE Conference
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• 2004.07c
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• pp.1891-1893
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• 2004

이 논무에서는 유입식 변압를 대상으로 UHF 대역의 펄스신호를 검출하는 센서를 소개하고, 이를 이용한 방전 결함별 측정 결과를 소개한다. 측정결과는 기존의 PRPD법과 주파수 Domain과 위상 Domain에 대한 정보를 가지는 p-f-q 분석으로 측정 하였으며, 본 논문에서는 후자의 결과를 중심으로 서술 하였다.

• 한국정보디스플레이학회:학술대회논문집
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• 2004.08a
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• pp.1040-1043
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• 2004

As time goes by, the market demand increases and each LCD panel manufacturing company makes every effort to produce more panels in a limited time. It is necessary to reduce the cost and time of production for the improvement of productivity in manufacturing companies. The increased speed of thin films growth used in the TFT process brings improvement of productivity but it is also accompanied by a drop in display quality due to a characteristic change of the thin film. So in our dissertation, we deal with the increased speed of a-Si layer growth and the proportioned a drop in characteristic quality. We discuss a drop in display quality by a characteristic change of a-Si layer and we propose a counter-plan through panel design improvement. We have already applied our plan to the 15" XGA panel and confirmed the improved result.

• Proceedings of the KIEE Conference
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• 2003.10b
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• pp.60-62
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• 2003

본 연구는, 초고압 GIS(Gas Insulated Switchgear)용 GCB(Gas Circuit Breaker)의 3상 배치구조를 설계 하기 위한 상간, 대지간의 절연성능을 평가하였다. 피임펄스 전압과 상용주파 전압인가시 상간, 대지간의 절연설계 기준과 비교하여 절연설계 안전율을 고려하여 설계에 적용하였다. 수치적 전계 해석법으로 3차원 전계 해석법과 2차원 축대칭 전계 해석법을 통해 전계 강도를 비교하였으며 3차원 전계 해석법으로는 경계 요소법(Boundary Element Method)을 사용하는 상용프로그램인 coulomb을 사용하였으며, 2차원 전계 해석법으로는 유한요소법(Finite Element Method)을 사용하는 Maxwell을 통해 절연성능 평가를 하였다. 마지막으로, 전계 해석을 통해 절연설계 기준에 적합한 상배치 구조 설계를 하였다.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2007.11a
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• pp.1028-1030
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• 2007

Mutual compensating concept between SIL(Solid Immersion Lens) and OL(Objective Lens) of NFR(Near Field Recording) is proposed, designed and manufactured to achieve a high NA and obtain a wider manufacturing tolerance. Tolerance information is present in article. An effective NA of Advanced SIL is 1.7 and adjustment between OL and SIL is carried out using our interferometer. We measured very clear RF signal using 3-axis actuator at Test bed.

• 한국정보디스플레이학회:학술대회논문집
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• 2008.10a
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• pp.598-600
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• 2008

In order to improve the contrast ratio of PDPs in the bright room, we decreased the panel reflection by coating phosphors with pigments. In this work, we investigated the panel reflectance with various sizes of the blue pigments and obtained good results by reducing the size of the pigment properly.