The present study examined the rate of cell growth and differentiation potential into adipocytes in A549 lung adenocarcinoma cells exposed to each adipogenic medium containing glucose metabolism hormones, such as thyroxine (T4) thyroid hormone and glucocorticoid (GC) adrenal steroid hormone, as well as pioglitazone (PGZ), a PPARγ agonist. Following each adipogenic treatment for 2 weeks, the rate of cell growth was significantly (p<0.05) inhibited, and the level of telomerase activity was significantly (p<0.05) decreased in the PGZ-based adipogenic medium containing both T4 and GC hormone compared with those containing each T4 or GC hormone. Moreover, the adiposome-like vesicles were highly reacted with Oil-Red O staining solution, and the levels of transcripts expressed in the differentiating adipocytes for adipogenesis, including adinopectin, leptin, and resistin, were significantly (p<0.05) increased in the PGZ-based adipogenic medium containing both T4 and GC hormone compared with those of the adipogenic medium containing each T4 or GC hormone, implying that adipocytic differentiation has fully occurred in the A549 cancer cells. Based on present observations, the PGZ-based adipogenic medium containing both T4 and GC efficiently induces inhibition of cell growth and cellular differentiation into adipocytes in A549 cancer cells rather than in the adipogenic medium containing only T4 or GC hormone. Adipogenic treatment could provide potential probability in cancer chemotherapy.
A wireless sensor network which is deployed in hostile environment can be easily compromised by attackers. The selective forwarding attack can jam the packet or drop a sensitive packet such as the movement of the enemy on data flow path through the compromised node. Xiao, Yu and Gao proposed the checkpoint-based multi-hop acknowledgement scheme(CHEMAS). In CHEMAS, each path node enable to be the checkpoint node according to the pre-defined probability and then can detect the area where the selective forwarding attacks is generated through the checkpoint nodes. In this scheme, the number of hops is very important because this parameter may trade off between energy conservation and detection capacity. In this paper, we used the fuzzy rule system to determine adaptive threshold value which is the number of hops for the ACK packets. In every period, the base station determines threshold value while using fuzzy logic. The energy level, the number of compromised node, and the distance to each node from base station are used to determine threshold value in fuzzy logic.
The purpose of this study is to suggest how to investigate the reliability of the assessment, which consists of items generated by automatic item generation using empirical example data. To achieve this, we analyzed the illustrative assessment data by applying the multivariate generalizability theory, which can reflect the design of responding to different items for each student and multiple error sources in the assessment score. The result of the G-study showed that, in most designs, the student effect corresponding to the true score of the classical test theory was relatively large after residual effects. In addition, in the design where the content domain was fixed, the ranking of students did not change depending on the item types or items. Similarly, in the design where the item format was fixed, the difficulty showed little variation depending on the content domains. The result of the D-study indicated that the original assessment data achieved a sufficient level of reliability. It was also found that higher reliability than the original assessment data could be obtained by reducing the number of items in the content domains of operation, geometry, and probability and statistics, or by assigning higher weights to the domains of letters and formulas, and function. The efficient measurement conditions presented in this study are limited to the illustrative assessment data. However, the method applied in this study can be utilized to determine the reliability and to find efficient measurement conditions for the various assessment situations using automatic item generation based on measurement traits.
This study conducted research on creating an environment for maker education programs for robot and SW education, development and application of maker education programs for low-grade elementary school students in farming and fishing villages. Based on the preceding maker education model, the OMCSI model was developed for the lower grade level of elementary school, and based on this, five WeDo-utilized elementary maker education programs were developed. From April 1, 2020 to October 30, 2020, the results of applying the elementary school maker education program using WeDo Robot 2.0 to 10 second graders of 10 Elementary School in Gyeongsangnam-do are as follows. The average increased by 3.40 points (t=-2.378, p=0.034) and the average increased by 3.30 points (t=-2.329, p=0.040). The average was also increased by 3.40 points (t=-2.458, p=0.038). Finally, it rose to 3.70 points (t=-2.449, p=0.037) for its reasoning ability. That is, all four sub-elements of computing thinking had a significant probability of 0.04, indicating statistical significant differences between scores of pre-post computing thinking. Therefore, the Elementary Maker Education Program using WeDo robots has worked very effectively to improve students' computing thinking skills.
KSCE Journal of Civil and Environmental Engineering Research
/
v.28
no.6D
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pp.791-799
/
2008
To build the system which has high utilization and usefulness for users, it is necessary to know the information type and use-demand that the use want. The purpose of this study is to forecast the preference and demand of utilization for bus information when bus information is offered through cellular phon. The accomplishments of this research are as follow : Firstly, importance on the level of individual factor and the value of change's figure can be evaluated, using preference analysis on bus information by conjoint analysis. Secondly, by establishing the use-demand model bus information using binary logit model, influence factor on whether or not the use of the user. Finally, ordered probit model was built by use behavior model in payment per call or per month of potential user of bus information. Through call times and sensitive analysis by payment methods, elasticity point, optimal payment fee, and use probability was analyzed. This study make application as basic to efficient bus information policy and to improve use rate of bus information in future because this study make it possible to get preference analysis, use-demand analysis and estimation of optimal payment fee which is reflecting various requirement in use of bus information user.
KSCE Journal of Civil and Environmental Engineering Research
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v.30
no.2B
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pp.169-177
/
2010
Recently due to the typhoon and extreme rainfall induced by abnormal weather and climate change, the probability of severe damage to human life and property is rapidly increasing. Thus it is necessary to create adequate and reliable flood risk map in preparation for those natural disasters. The study area is Seo-gu in Daegu which is located near Geumho river, one of the tributaries of Nakdong river. Inundation depth and velocity at each time were calculated by applying FLUMEN model to the target area of interest, Seo-gu in Daegu. And the research of creating flood risk map was conducted according to the Downstream Hazard Classification Guidelines of USBR. The 2-dimensional inundation analysis for channels and protected lowland with FLUMEN model was carried out with the basic assumption that there's no levee failure against 100 year precipatation and inflow comes only through the overflowing to the protected lowland. The occurrence of overflowing was identified at the levee of Bisan-dong located in Geumho watershed. The level of risk was displayed for house/building residents, drivers and pedestrians using information about depth and velocity of each node computed from the inundation analysis. Once inundation depth map and flood risk map for each region is created with this research method, emergency action guidelines for residents can be systemized and it would be very useful in establishing specified emergency evacuation plans in case of levee failure and overflowing resulting from a flood.
The purpose of this study is to find out the characteristics of elderly pedestrian accidents and to suggest policy implications to enhance the level of elderly pedestrian safety. Although much efforts has made to enhance traffic safety environment, pedestrian traffic accidents among elderly population are not significantly decreased. This is mainly because current traffic safety measures do not much consider the characteristics of elderly pedestrians in the aspects of physical and psychological conditions. Main findings from vehicle-pedestrian traffic accident data and survey are as follows. First elderly pedestrians have high probability of traffic accident near crosswalks or cross streets rather than on crosswalk or cross streets. Second they need more green light time for crossing the streets. Third, they feel motor cycles running on the side walk and parked vehicles on the side walk are the most dangerous factors. Forth, general drivers do not have reasonable understanding for the walking behaviors of elderly pedestrians. Fifth, elderly pedestrians frequently need to rest while walking. Sixth, elderly people do not see clearly or understand traffic signs. Finally, many elderly pedestrians experience accidents or inconvenience while walking on the sidewalk.
Hyung Jun Park;Dong Hyun Kim;Hyun Jung Lee;Seung Oh Lee
Journal of Korean Society of Disaster and Security
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v.16
no.2
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pp.85-98
/
2023
Flood is one of the most frequent natural disasters worldwide. In Korea, the probability of urban flooding is greatly increasing due to complex factors such as global warming, an increase in impervious areas, and limitations in expanding water supply facilities in existing urban areas. However, large-scale civil engineering works to prevent urban inundation are socially and economically difficult to obtain national consent. Recently the importance of resilience, which is the ability to return to the original state after a disaster through rapid recovery while preparing for natural disasters to a level that the local community can afford socially and economically, is increasing. Accordingly, various studies on urban resilience have been conducted, but the resilience measurement method related to the lifeline that provides essential services of the city is insufficient. However, among lifelines, road networks are important facilities for the transportation of recovery resources and rapid recovery in the event of a natural disaster, so road networks are a major factor that must be considered when measuring the degree of recovery of a city in the field of natural disasters. Therefore, this study proposes a recovery evaluation method considering the characteristics of resilience and road networks in the urban flooding field and analyzes the effect of road networks on urban resilience.
This study conducted an empirical analysis on a land purchase requisition policy in Bukhansan National Park to draw the efficacy, limitations and implications of this policy. A logistic regression analysis was conducted to identify factors that affected the landowners' decision on applying for land purchase requisition using the government's records on acquisition of private lands in the park since 2006 when this policy began to be implemented. Results illustrate that the probability that a landowner applied for purchase requisition increased if the land was classified as forest, if a large proportion of the land was designated as the nature conservation district, if it was located farther from park boundary, and if it had higher appraised value per square meter. These results indicate that as the landowners had less chance to utilize their lands, they more likely apply for purchase requisition. These results also imply that the government can achieve a high conservation performance level if private lands are acquire by the land acquisition requisition policy. The logistic regression model also predict that 401m2 of the private lands in Bukhansan National Park will likely be purchase-requested in future. Despites its usefulness in mitigating landowners' complaints in national parks, the land purchase requisition policy has not been widely utilized. Based on these empirical results, this study provides policy implications to facilitate the ulitization of this policy.
Fostering trusting belief in financial transactions is a challenging task in Internet banking services. Authenticated Certificate had been regarded as an effective method to guarantee the trusting belief for online transactions. However, previous research claimed that this method has some loopholes for such abusers as hackers, who intend to attack the financial accounts of innocent transactors in Internet. Two types of methods have been suggested as alternatives for securing user identification and activity in online financial services. Control transparency uses information over the transaction process to verify and to control the transactions. Outcome feedback, which refers to the specific information about exchange outcomes, provides information over final transaction results. By using these two methods, financial service providers can send signals to involved parties about the robustness of their security mechanisms. These two methods-control transparency and outcome feedback-have been widely used in the IS field to enhance the quality of IS services. In this research, we intend to verify that these two methods can also be used to reduce risks and to increase the security protections in online banking services. The purpose of this paper is to empirically test the effects of the control transparency and the outcome feedback on the risk perceptions in Internet banking services. Our assumption is that these two methods-control transparency and outcome feedback-can reduce perceived risks involved with online financial transactions, while increasing perceived trust over financial service providers. These changes in user attitudes can increase the level of user satisfactions, which may lead to the increased user loyalty as well as users' willingness to pay for the financial transactions. Previous research in IS suggested that the increased level of transparency on the process and the result of transactions can enhance the information quality and decision quality of IS users. Transparency helps IS users to acquire the information needed to control the transaction counterpart and thus to complete transaction successfully. It is also argued that transparency can reduce the perceived transaction risks in IS usage. Many IS researchers also argued that the trust can be generated by the institutional mechanisms. Trusting belief refers to the truster's belief for the trustee to have attributes for being beneficial to the truster. Institution-based trust plays an important role to enhance the probability of achieving a successful outcome. When a transactor regards the conditions crucial for the transaction success, he or she considers the condition providers as trustful, and thus eventually trust the others involved with such condition providers. In this process, transparency helps the transactor complete the transaction successfully. Through the investigation of these studies, we expect that the control transparency and outcome feedback can reduce the risk perception on transaction and enhance the trust with the service provider. Based on a theoretical framework of transparency and institution-based trust, we propose and test a research model by evaluating research hypotheses. We have conducted a laboratory experiment in order to validate our research model. Since the transparency artifact(control transparency and outcome feedback) is not yet adopted in online banking services, the general survey method could not be employed to verify our research model. We collected data from 138 experiment subjects who had experiences with online banking services. PLS is used to analyze the experiment data. The measurement model confirms that our data set has appropriate convergent and discriminant validity. The results of testing the structural model indicate that control transparency significantly enhances the trust and significantly reduces the risk perception of online banking users. The result also suggested that the outcome feedback significantly enhances the trust of users. We have found that the reduced risk and the increased trust level significantly improve the level of service satisfaction. The increased satisfaction finally leads to the increased loyalty and willingness to pay for the financial services.
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