• Title/Summary/Keyword: length of the baseline

Search Result 234, Processing Time 0.028 seconds

SIFamide and SIFamide Receptor Define a Novel Neuropeptide Signaling to Promote Sleep in Drosophila

  • Park, Sangjin;Sonn, Jun Young;Oh, Yangkyun;Lim, Chunghun;Choe, Joonho
    • Molecules and Cells
    • /
    • v.37 no.4
    • /
    • pp.295-301
    • /
    • 2014
  • SIFamide receptor (SIFR) is a Drosophila G protein-coupled receptor for the neuropeptide SIFamide (SIFa). Although the sequence and spatial expression of SIFa are evolutionarily conserved among insect species, the physiological function of SIFa/SIFR signaling remains elusive. Here, we provide genetic evidence that SIFa and SIFR promote sleep in Drosophila. Either genetic ablation of SIFa-expressing neurons in the pars intercerebralis (PI) or pan-neuronal depletion of SIFa expression shortened baseline sleep and reduced sleep-bout length, suggesting that it caused sleep fragmentation. Consistently, RNA interference-mediated knockdown of SIFR expression caused short sleep phenotypes as observed in SIFa-ablated or depleted flies. Using a panel of neuron-specific Gal4 drivers, we further mapped SIFR effects to subsets of PI neurons. Taken together, these results reveal a novel physiological role of the neuropeptide SIFa/SIFR pathway to regulate sleep through sleep-promoting neural circuits in the PI of adult fly brains.

Breeding Status and Ecology of Saunders' Gulls (Larus saundersi) in Songdo Reclaimed Land, West Coast of Korea (서해안 송도매립지에서 번식하는 검은머리갈매기의 현황과 번식생태)

  • Kwon, Young-Soo;Chung, Hoon
    • Ocean and Polar Research
    • /
    • v.31 no.3
    • /
    • pp.277-282
    • /
    • 2009
  • Saunders' gulls (Laurs saundersi) which are listed as globally vulnerable species on the IUCN Red List are distributed in East Asia and breed mainly in China and Korea. Their population is estimated to be between 7,100 to 9,600. Songdo reclaimed lands in the western coast of South Korea are the main breeding sites for these species. However, most of these breeding sites have been seriously disturbed in the last several years because of new urban development constructions. This study was conducted to provide baseline data on the breeding ecology of Saunders' gulls. Since 1998, the breeding population has rapidly increased in South Korea, with the number of nests rising from 85 nests in 2000 to 185 nests in 2005. Egg volume is more variable than breadth or length. Clutch size, hatching and breeding success were $2.9{\pm}0.81$ (n=182, mean$\pm$sd.), 48.07% (75 hatched egg/156 eggs) and 29.08% (155 fledglings/533 eggs), respectively. Factors affecting breeding failure were predation, rainfall, starvation and supernormal clutches. These results are provided along with other cited literature to argue for conservation of Saunders' gulls.

Two-Site Optical Observation and Initial Orbit Determination for Geostationary Earth Orbit Satellites

  • Choi, Jin;Choi, Young-Jun;Yim, Hong-Suh;Jo, Jung-Hyun;Han, Won-Yong
    • Journal of Astronomy and Space Sciences
    • /
    • v.27 no.4
    • /
    • pp.337-343
    • /
    • 2010
  • Optical observation system provides angle-only measurement for orbit determination of space object. Range measurement can be directly acquired using laser ranging or tone ranging system. Initial orbit determination (IOD) by using angle- only data set shows discrepancy according to the measurement time interval. To solve this problem, range measurement data should be added for IOD. In this study, two-site optical observation was used to derive the range information. We have observed nine geostationary earth orbit satellites by using two-site optical observation system. The determination result of the range shows the accuracy over 99.5% compared to the results from the satellite tool kit simulation. And we confirmed that the orbit determination by the Herrick-Gibbs method with the range information obtained from the two-site observation is more accurate than the orbit determination by Gauss method with the one-site observation. For more accurate two-site optical observation, a baseline should satisfy an optimal condition of length and more precise observation system needed.

Characteristics and Key Parameters of Dual Bell Nozzles of the DLR, Germany (독일 DLR의 듀얼 벨 노즐 특성 및 핵심 변수)

  • Kim, Jeonghoon;Huh, Hwanil
    • Journal of the Korean Society for Aeronautical & Space Sciences
    • /
    • v.43 no.11
    • /
    • pp.952-962
    • /
    • 2015
  • Various types of altitude compensation nozzles have been investigated to develop an effective propulsion system. In order to obtain baseline data for future study of dual bell nozzles, main characteristics and key parameters of dual bell nozzles are summarized and described by analysing DLR dual bell nozzles. DLR's experimental researches show that inflection angle is proportional to transition NPR, and extension length is proportional to side load, but inversely proportional to transition NPR and transition duration. Therefore, the nozzle geometry can be determined through the performance prediction process and thus the optimization process is required to meet performance requirements between parameters.

Adjuvant Sertraline Treatment for Chronic Schizophrenia : A Randomized, Double Blind, Placebo-Controlled Study (만성 정신분열증환자에 대한 Sertraline병합치료 효과)

  • Lee, Min-Soo;Kim, Yong-Ku;Lee, Sang-Kyu;Suh, Kwang-Yoon
    • Korean Journal of Biological Psychiatry
    • /
    • v.4 no.1
    • /
    • pp.127-131
    • /
    • 1997
  • Objective : To evaluate the clinical efficacy of adjuvant sertraline treatment in chronic schizophrenic patients, we carried out a double-blind, placebo controlled study. Method : Thirty six inpatients who fulfilled DSM-III-R criteria for chronic schizophrenia were randomly assigned to sertraline and placebo groups in a double-blinded fashion. A history of at least 2 years of illness and at least six months of hospitalization were prerequisities for inclusion in the study. Patients were received sertraline 50mg or placebo for 8 weeks in addition to their routine haloperidol regimen. Positive and Negative Syndrome Scale (PANSS), Clinical Global Impression(CGI), Simpson-Angus Scale(S-A) were evaluated at 5 points ; baseline, 2, 4, 6, and 8 weeks of treatment. Results : The groups were controlled for age, gender, and length of illness. There were no significant differences in three PANSS factros(positive, negative, general), CGI, and S-A scale scores at any between sertaline and placebo treatment. Conclusion : This placebo controlled study showed no significant effects of sertraline on negative and positive symptoms in chronic schizophrenic patients.

  • PDF

Altitude Estimation Improvement in DGPS using Barometric Altitude Sensors (기압 고도계를 이용한 DGPS 고도측정 향상)

  • Yu, Ho;Lee, Yeong-Jae;Ji, Gyu-In;Cheon, Se-Beom;Gwon, Cheol-Beom;Jeon, Hyang-Sik;Ju, Jeong-Min
    • Journal of the Korean Society for Aeronautical & Space Sciences
    • /
    • v.34 no.1
    • /
    • pp.89-94
    • /
    • 2006
  • DGPS provides less altitude accuracy than horizontal accuracy according to geometric characteristics of GPS satellite arrangement. To assist DGPS altitude measurements, two barometric altitude sensors were used and set up at the mobile and the reference station respectively to get the differential altitude. This differential altitude is coupled with the DGPS altitude measurement by a Kalman filter so that the improved altitude is estimated. The differential altitude is based on the relative altitude measurement but results in providing the absolute altitude. The precision of this differential altitude is verified by experiments in accordance with a baseline length.

Analysis of Direction Finding Accuracy for Amplitude-Phase Comparison and Correlative Interferometer Method (진폭-위상 복합비교 기법과 상관형 위상비교 기법의 방향탐지 정확도 분석)

  • Lim, Joong-Soo;Chae, Gyoo-Soo
    • Journal of Digital Convergence
    • /
    • v.14 no.1
    • /
    • pp.195-201
    • /
    • 2016
  • In this paper, we present the direction finding accuracy of correlative interferometer method and amplitude-phase comparison method. Spiral antennas are used for amplitude-phase comparison method and blade antennas are used for correlative interferometer method. Those are made for uniform circular array (UCA) direction finding antenna systems. We simulate the accuracy of azimuth angle with 3 antennas UCA when SNR is 20 dB and baseline is 0.5 wave length. Correlative interferometer method has better accuracy than amplitude-phase comparison method.

An Effective Approach Using Sentence Symbols to Identify Maximal-Length Noun Phrase in Chinese (문장부호를 사용한 효과적인 중국어 최장명사구 식별기법)

  • Bai Xue-Mei;Li Jin-Ji;Jin Mei-Xun;Cheng You-Jin;Lee Jong-Hyeok
    • Proceedings of the Korean Information Science Society Conference
    • /
    • 2005.07b
    • /
    • pp.454-456
    • /
    • 2005
  • 일반적으로 중국어의 명사구는 최단명사구, 기본명사구 최장명사구로 분류된다. 최장명사구에 대한 정확한 식별은 문장의 전체적인 구조를 파악하고 문장의 정확한 지배용언을 찾아내는데 중요한 역할을 한다. 본 논문에서는 특성에 따라 5개의 클래스로 세분화된 문장부호를 학습자질로 사용하여 최장명사구 자동식별을 진행한다. 제안된 기법은 평균길이가 4인 최장명사구의 식별실험에서 기본모델(baseline)보다 $4.5\%$ 향상된 평균 $85.1\%$의 우수한 F-measure 성능을 보인다.

  • PDF

Effects of the Progression Control of Myopia on Myopia Control Lenses and Single Vision Lenses (Myopia Control 렌즈와 Single Vision 렌즈의 근시진행 조절 효과)

  • Jung, Ji-Won;Lee, Ki-Seok;Yoo, Wang-Keun
    • Journal of Korean Ophthalmic Optics Society
    • /
    • v.17 no.1
    • /
    • pp.19-26
    • /
    • 2012
  • Purpose: This paper was to study the clinical effects of moderating myopia by comparing the myopia control lens, which was being recently recognized as a method of inhibiting the progression of myopia, with the wearers of single vision lens. Methods: Using 56 subjects between the ages of 8-15 years (112 eyes) with myopia in the areas of City of Daegu and Gyeongsangbuk Province as study subjects, refractive error, axial length, near point of convergence and accommodative near point were measured and compared a total of 3 times at the baseline, after 1-month and after 6-months. Results: For refractive error, suppression and mitigation were seen in the progression of spherical equivalent when MC lens was worn, as compared to using SV lens, and, when axial length MC lens was worn, the axial progression was significantly suppressed and delayed (p < 0.05). The near point of convergence became shorter with the use of MC lens, and the amplitude of convergence was improved when MC lens was worn. Accommodative near point became shorter with the use of MC lens, and focus ability was significantly improved (p <0.05). Conclusions: It was shown that MC lens, compared to SV lens, could alleviate myopia progression in school-age children and youth. It is considered that MC lens can be used as a useful therapy for the inhibition of myopia progression in the increasing number of myopic children and adolescents.

Factors Associated with a Prolonged Length of Hospital Stay in Patients with Diabetic Foot: A Single-Center Retrospective Study

  • Choi, Sang Kyu;Kim, Cheol Keun;Jo, Dong In;Lee, Myung Chul;Kim, Jee Nam;Choi, Hyun Gon;Shin, Dong Hyeok;Kim, Soon Heum
    • Archives of Plastic Surgery
    • /
    • v.44 no.6
    • /
    • pp.539-544
    • /
    • 2017
  • Background We conducted this study to identify factors that may prolong the length of the hospital stay (LHS) in patients with diabetic foot (DF) in a single-institution setting. Methods In this single-center retrospective study, we evaluated a total of 164 patients with DF, and conducted an intergroup comparison of their baseline demographic and clinical characteristics, including sex, age, duration of diabetes, smoking status, body mass index, underlying comorbidities (e.g., hypertension or diabetic nephropathy), wound characteristics, type of surgery, the total medical cost, white blood cell (WBC) count, C-reactive protein (CRP) levels, erythrocyte sedimentation rate, and albumin, protein, glycated hemoglobin, and 7-day mean blood glucose (BG) levels. Results Pearson correlation analysis showed that an LHS of >5 weeks had a significant positive correlation with the severity of the wound (r=0.647), WBC count (r=0.571), CRP levels (r=0.390), DN (r=0.020), and 7-day mean BG levels (r=0.120) (P<0.05). In multiple regression analysis, an LHS of >5 weeks had a significant positive correlation with the severity of the wound (odds ratio [OR]=3.297; 95% confidence interval [CI], 1.324-10.483; P=0.020), WBC count (OR=1.423; 95% CI, 0.046.0-356; P=0.000), CRP levels (OR=1.079; 95% CI, 1.015-1.147; P=0.014), albumin levels (OR=0.263; 95% CI, 0.113.3-673; P=0.007), and 7-day mean BG levels (OR=1.018; 95% CI, 1.001-1.035; P=0.020). Conclusions Surgeons should consider the factors associated with a prolonged LHS in the early management of patients with DF. Moreover, this should also be accompanied by a multidisciplinary approach to reducing the LHS.