• 한국발생생물학회지:발생과생식
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• 제11권2호
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• pp.121-125
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• 2007

넙치 자치어의 초기 발육단계에 따른 소화관의 형태 발달과정을 관찰한 결과, 부화 직후의 전기 자어는 평균전장 $25.0{\pm}0.14\;mm$(n=20)로 입과 항문이 아직 열려 있지 않았고, 소화관은 배체와 난황 사이에 원시 소화관의 형태로 거의 직선상으로 식도에서 항문이 생길 부분까지 길게 신장되어 있는 형태였다. 부화 후 $7{\sim}8$일째 후기 자어는 평균 전장 $5.05{\pm}0.40\;mm$(n=20)로 소화관이 발달하여 먹이의 섭취활동이 활발하였으며, 소화관은 배쪽으로 팽창하여 장과 연결되어 위가 발달하기 시작하였고, 소화관의 전반부와 후반부가 구별되어 소화기관이 분화하기 시작하였다. 부화 후 $13{\sim}14$일째 후기 자어는 전장이 $6.50{\pm}0.25\;mm$(n=20)였고, 소화관은 앞부분에서부터 1회전되어 회전부분의 면적이 넓어져 있었으며, 소화관이 식도, 전장, 중장, 후장으로 완전히 분화되면서 소화관의 기본적인 구조가 확립되었다. 부화 후 30일째 개체는 전장 $12.40{\pm}0.55\;mm$(n=20)로 위는 비대하여 분문부와 유문부가 뚜렷하게 구별되었고, 소화관은 위, 전장, 중장, 후장 및 직장이 명확하게 구분되어 치어기로 이행하여 성어와 유사한 구조로 발달하였다. 부화 후 40일째 치어는 전장이 $16.15{\pm}0.85\;mm$(n=20)로 소화관 형태는 식도부, 유문부, 장의 전장, 중장, 직장이 크게 팽창되어 상대적으로 후기 자어의 소화관 형태와는 다소 차이가 있었다.

• Clinical Endoscopy
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• 제56권3호
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• pp.283-289
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• 2023

Gastrointestinal (GI) bleeding is one of the most common conditions among patients visiting emergency departments in Korea. GI bleeding is divided into upper and lower GI bleeding, according to the bleeding site. GI bleeding is also divided into overt and occult GI bleeding based on bleeding characteristics. In addition, obscure GI bleeding refers to recurrent or persistent GI bleeding from a source that cannot be identified after esophagogastroduodenoscopy or colonoscopy. The small intestine is the largest part of the alimentary tract. It extends from the pylorus to the cecum. The small intestine is difficult to access owing to its long length. Moreover, it is not fixed to the abdominal cavity. When hemorrhage occurs in the small intestine, the source cannot be found in many cases because of the characteristics of the small intestine. In practice, small-intestinal bleeding accounts for most of the obscure GI bleeding. Therefore, in this review, we introduce and describe systemic approaches and examination methods, including video capsule endoscopy and balloon enteroscopy, that can be performed in patients with suspected small bowel bleeding in clinical practice.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2022년도 추계학술대회
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• pp.2-5
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• 2022

사람의 체내 장기는 복잡한 구조로 되어있으며 특히, 소장은 길이가 약 7m 길이를 가지고 있어 내시경 검사가 쉽지 않고 내시경 검사 시 위험도가 높다. 현재는 캡슐 내시경으로 검사를 수행하고 있으며, 검사 시간이 매우 긴 편이다. 의사는 제거된 저장장치를 컴퓨터에 연결해 환자의 캡슐 내시경 영상을 저장 후 프로그램을 사용하여 판독하지만, 캡슐 내시경 검사 결과 영상 길이가 길어 판독 시간이 많이 소요된다. 또한 소장의 경우 융모에 의해 많은 굴곡이 존재해 검사 과정에서 영상의 폐색 영역이나 명암이 뚜렷이 나타나게 되어 검사 시 병변 및 이상징후에 관해 놓치는 경우가 발생할 수 있다. 본 논문에서는 의사의 영상 판독 시간 단축과 진단 신뢰도 향상을 위해 인공신경망을 이용한 소장 캡슐 내시경 병변 검사 보조 방법을 제공한다.

• Asian-Australasian Journal of Animal Sciences
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• 제13권11호
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• pp.1499-1507
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• 2000

This trial was to compare the digestive function of laboratory animals, which included omnivores (rats) and herbivores (rabbits, guinea pigs and hamsters). Ten weanling rats, rabbits, guinea pigs and hamster were randomly allocated in individual metabolic cages for a performance and a digestibility trial. Results showed that guinea pigs were significantly best in digestion of dietary crude protein and fiber. Rabbits, however, had the poorest nutrient digestion among the herbivores. Crude fiber digested significantly less by rats than by the herbivores (p<0.05). The digesta retention in the GI tract was longest in rabbits followed by guinea pigs, rats and hamsters. The relative length of the large intestine was significantly shorter in rats as compared to guinea pigs or hamsters. Both the weight and length ratio of the caecum or colon-rectum to the large intestine reflected the major site for fermentation that was the caecum in rabbits and the colon-rectum in guinea pigs. 10% of crude fiber diet did not result in damaged mucosa in any of the experimental animals in this trial.

• Asian-Australasian Journal of Animal Sciences
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• 제11권4호
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• pp.375-380
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• 1998

Six Holstein heifer calves weaned at 45 days-of-age were randomly allocated into high daily gain (1.1 kg/d, HDG) and low daily gain (0.56 kg/d, LDG) groups, and were slaughtered at 170 kg of live weight. Energy intake level in the feeding period was 2.4 $\times$ maintenance in 105 days for HDG and 1.4 $\times$ maintenance in 216 days for LDG calves. Total length of the small intestine was identical between groups, but both weights of the pancreas and of the small intestinal mucosa were greater (p < 0.01) for HDG calves. Alpha-amylase, lipase, proteinase, and trypsin activities of the whole pancreas were higher (p < 0.05) in HDG calves. Disaccharidase activity of the whole small intestinal mucosa was also higher (p < 0.10) for HDG than for LDG calves. However, the enzymatic activities, expressed as per gram or per protein of the pancreas and the small intestinal mucosa, were not affected (p > 0.10) by the plane of nutrition. These results suggest that the digestive enzyme activity in the small intestine varies primarily with the weight of tissues synthesizing the enzyme.

• Journal of Nutrition and Health
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• 제29권2호
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• pp.153-158
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• 1996

Polyethylene glycols(PEGs)are hydrophilic molecules that have been used to characterize intestinal permeability via the paracellular pathway. Using a mixture of PEGs(400, 600 and 1000), containing oligomers in the molecular weight range 330 to 1122 D, the molecular weight permeability dependence in the jejunum of the rat small intestine was examined, employing an in situ recirculation perfusion technique. Individual oligomers were determined by HPLC with refractive detection. In the range studied, a distinct molecular weight cut-off was not apparent. Corrected for the length of jejunum used in the study, over the molecular weight range 330 to 1122D, the apparent permeability(Papp) of PEG ranged from 4.92$\pm$0.02$\times$10-5cm/sec(mean$\pm$SEM, n=5) to 0.28$\times$10-5cm/sec. Also, it was observed that the apparent permeability was inversely proportional to approximately MW2. The results in this study suggest that molecular weight is an important factor in determining the intestinal permeability.

• Asian-Australasian Journal of Animal Sciences
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• 제20권7호
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• pp.1084-1091
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• 2007

Different levels of dietary mannanoligosaccharide (Bio-MOS, Alltech Inc.) were evaluated for their efficacy on performance and gut development of broiler chickens during a 6-week experimental period. Experimental diets contained (g MOS/kg diet) a low (0.5 g during the entire period), medium (1 g during the entire period), high (2 g during the entire period), or step down (2 g in the first week; 1 g in the second and third week; 0.5 g in the last three weeks) level of MOS. Control diets included a negative and a positive control (zinc bacitracin, ZnB, 50 ppm and 30 ppm in the first and last three weeks, respectively). MOS supplementation improved the growth performance of young birds and the effects became less when the birds got older. The growth response of birds was more obvious at the high dosage level of MOS treatment than the other MOS treatments and the growth performance of birds fed on the high MOS diet was comparable to that of birds fed on the ZnB diet. Depending on the dosage level and the age of birds, MOS seemed to reduce the size of the liver and the relative length of the small intestine but did not affect the relative weight of the other visceral organs (proventriculus, gizzard, pancreas, bursa and spleen) and that of the small intestine. A numerical increase in the small intestine digestibility of nutrients was noticed in the young birds fed on the MOS diet(s), but not in the older ones. Medium and/or high MOS treatment also increased the villus height of the small intestine of birds at different ages. Similar results were observed on the ZnB treatment. However, MOS and ZnB affected caecal VFA profile in different ways. MOS increased, or tended to increase, whereas ZnB reduced individual VFA concentrations in the caeca.

• 한국가금학회지
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• 제50권1호
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• pp.31-39
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• 2023

The objective of this study was to investigate the effect of exogenous protease supplementation in diets formulated with poultry by-product meal on growth performance, small intestine magnitudes, and meat physiochemical characters in broiler chickens from 21 to 35 days post-hatch. A total of 120, one-day-old "Arbor Acres Plus" broiler chickens (male: female - 50:50) were allocated one of two dietary treatments to give six replicates and ten birds per cage. Two dietary treatments included a control diet (CON) and a diet supplemented with protease (CON+Pro). At day 35, body weight and feed intakes were measured to calculate the feed conversion ratio for the entire experiment period. Two birds from each pen were euthanized to measure the relative lengths and relative weights of three small intestine sections and meat samples were collected for physiochemical characteristic analyses at 35 days post-hatch. Exogenous protease supplementation did not influence (P>0.05) growth performance but showed a tendency to improve FCR (P=0.082). Protease supplementation showed a tendency to reduce proximal small intestine length (P=0.091). Broilers offered dietary treatments influenced minced meat color where protease supplementation resulted in lower CIE b^* (P<0.001) colorimetric value for yellowness and showed a significant trend (P=0.059) on reducing meat redness CIE a^*. In conclusion, the addition of exogenous protease to a broiler diet formulated with poultry by-product meal did not affect the growth performance, small intestine magnitudes, and meat physiochemical parameters (except CIE b^*) in broiler chickens.

• 한국수산과학회지
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• 제9권4호
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• pp.273-280
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• 1976

1976년 6월 20일에 해운대 동백섬 연안에서 채집된 황아귀의 자어를 재료로 하여 초기생활사에 따른 형태변화 과정중 등지느러미 이극, 배지느러미, 색소포 및 소화관의 발적과정과 아가미, 새조 및 치아등의 형성과정에 관하여 관찰하였다. 1. 제1등지느러미 제1극의 원기는 부화직후인 2.7mm 전후에 생겨나 6.30mm 전후에서 극의 형태로 분화되며, 제2극은 5.82mm 전후에 원기가 나타나고 제3극은 6.45mm 전후에서 원기가 나타나 분화되는 것같다. 2. 배지느러미는 2.7mm 전후에 가슴지느러미의 바로 뒤쪽에서 원기가 나타나고, 처음에는 반원형으로 솟아나듯 하든 것이 차츰 발달함에 따라 뒤쪽으로 향해 곤봉상으로 길어지고, 전장 6.35mm 전후에서 전장의 1/2 정도의 크기로 발달하며, 가는 두 줄의 지느러미 줄기가 나타난다. 3. 색소포의 발달은 특히 미부에 있어서 2단계로 구분할 수 있는데, 부화직후(2.7mm 전후) 미부에 불규칙 9열로 분포하는 경우와 시일이 경과함에 따라 전장 4.25mm전후에는 뚜렷한 3개의 색소포군을 형성하는 경우를 들 수 있다. 4. 소화관은 부화직후인 2.7mm 전후에 창자의 시흔이 나타나기 시작하며 전장 5.4mm 전후에 난황이 축소되면서 창자의 굴곡등 소화관의 윤곽이 뚜렷해질 뿐만 아니라 입도 열리는 것 같다. 5. 아가미는 전장 6.35mm 전후에 시흔이 보이며 발달하기 시작하고 치아는 전장 6.25mm 전후에 원기가 나타나고 새조는 6.45mm 전후에 5개의 새조골을 볼 수 있다.

• Journal of Gastric Cancer
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• 제17권1호
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• pp.11-20
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• 2017

Purpose: Acupuncture has recently been accepted as a treatment option for managing postoperative ileus (POI) and various functional gastrointestinal disorders. Therefore, we conducted a prospective randomized study to evaluate the effect of acupuncture on POI and other surgical outcomes in patients who underwent gastric surgery. Materials and Methods: Thirty-six patients who underwent distal gastrectomy for gastric cancer from March to December 2015 were randomly assigned to acupuncture or non-acupuncture (NA) groups at 1:1 ratio. The acupuncture treatment was administered treatment once daily for 5 consecutive days starting at postoperative day 1. The primary outcome measure was the number of remnant sitz markers in the small intestine on abdominal radiograph. The secondary outcome measure was the surgical outcome, including the times to first flatus, first defecation, start of water intake, and start of soft diet, as well as length of hospital stay and laboratory findings. Results: The acupuncture group had significantly fewer remnant sitz markers in the small intestine on postoperative days 3 and 5 compared to those in the NA group. A significant difference was observed in the numbers of remnant sitz markers in the small intestine with respect to group differences by time (P<0.0001). The acupuncture group showed relatively better surgical outcomes than those in the NA group, but the differences were not statistically significant. Conclusions: In this clinical trial, acupuncture promoted the passage of sitz markers, which may reflect the possibility of reducing POI after distal gastrectomy.