• Structural Monitoring and Maintenance
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• 제4권4호
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• pp.381-396
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• 2017

Structural health monitoring (SHM) is a necessity for reliable and efficient functioning of engineering systems. Damage detection (DD) is a crucial component of any SHM system. Lamb waves are a popular means to DD owing to their sensitivity to small damages over a substantial length. This typically involves an active sensing paradigm in a pitch-catch setting, that involves two piezo-sensors, a transmitter and a receiver. In this paper, we propose a data-intensive DD approach for beam structures using high frequency signals acquired from beams in a pitch-catch setting. The key idea is to develop a statistical learning-based approach, that harnesses the inherent sparsity in the problem. The proposed approach performs damage detection, localization in beams. In addition, quantification is possible too with prior calibration. We demonstrate numerically that the proposed approach achieves 100% accuracy in detection and localization even with a signal to noise ratio of 25 dB.

• 한국습지학회지
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• 제13권3호
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• pp.395-409
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• 2011

본 연구의 목적은 개수로에서 난류모의를 위한 2차원 모형을 개발하는데 있다. 연구모델은 Streamline Upwind / Petrov-Galerkin 유한요소법과 Boussinesq의 와점성이론을 기초로 하였는데, 수심적분을 취한 혼합거리 모형과 난류의 이방성과 국부평형의 조건을 적용하였다. 모형의 보정과 검증을 위해서 해석해와 관측자료를 활용하였다. 몇 가지 수치모의를 수행함으로써 난류모형의 민감도와 계산수행 능력을 확인할 수 있었다. 본 연구모형은 자연하천에서의 모형 적용성 확인을 위해서 한강유역에 적용하였고 모의치는 실측자료와 비교하였다. 개발된 모형은 자연하천에서의 관측자료와 비교적 잘 일치하는 것으로 나타났다. 결론적으로 본 연구의 2차원 유한요소모형은 개수로에서의 난류모의에 기초한 흐름분포에 있어 신뢰할만한 결과를 제공하는 것으로 나타났다.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2004년도 추계학술대회
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• pp.55-60
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• 2004

This study is concerned to the perforation phenomena of the oblique dual-plate by projectile. Experiment and simulation related to that was carried out. the variables considered in this phenomena include the electrolytic zinc coated steel sheet and carbon steel rod. In the former, the confirmation and projectile velocity possible phenomena of real phenomena is done, the latter, the effect of parameter such as time-step and grid space length is analized by using the three-dimensional Lagrangian explicit time-integration finite element code, HEMP. this code use the eight node hexahedral elements and in this study, Von-Mises Criteria is used as the strength model, Mie-Gruneisen is as the Equation of State. the simulation was performed by contrast with the experiment. through the calibration of the parameter of lagrangian code, reasonable result was approached.

• Journal of Pharmaceutical Investigation
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• 제37권3호
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• pp.187-192
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• 2007

A reversed phase HPLC analysis of atorvastatin (AS) standard solution was performed using diclofenac (DF) as internal standard. Column oven temperature, flow rate and the composition of the mobile phase were varied in order to determine a practical system setup using a C18 column and UV detector. Two C18 columns of different length were compared regarding their influence on the AS peak shape. Based on these preliminary experiments a validation study was performed utilizing a C18 column at $62^{\circ}C$ with a mobile phase consisting of sodium phosphate buffer (0.05 M, pH 4.0), methanol and acetonitrile (40:50:10, v/v/v). The detection limit for AS was $0.1{\mu}g/ml$ and inter- and intra-day calibration curves were linear over a concentration range of $0.2-50{\mu}g/ml$. Accuracy and precision were satisfactory in the AS concentration range of $0.5-50{\mu}g/ml$.

• Structural Engineering and Mechanics
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• 제41권1호
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• pp.83-94
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• 2012

Assessment of a monumental concrete arch bridge with a total length of 210 meters having three major spans of 30 meters and a height of 65 meters, which is located in an earthquake-prone region in southern part of the country is presented in this study. Three-dimensional finite element model of the bridge was generated using a commercially available general finite element analysis software and based on the outcomes of a series of in-depth acceleration measurements that were conducted on-site, the model was refined. By using the structural parameters obtained from the dynamic and the static tests, calibrated model of the bridge structure was obtained and this model was used for necessary calculations regarding structural assessment and evaluation.

• 한국방송∙미디어공학회:학술대회논문집
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• 한국방송공학회 1999년도 KOBA 방송기술 워크샵 KOBA Broadcasting Technology Workshop
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• pp.125-131
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• 1999

In this paper, we address practical methods for calculating camera lens distortion for real time applications. Although the lens distortion problem can be easily ignored for constant-parameter lenses, in the field of real-time camera calibrations, for zoom lenses a large number of calculations are needed to calculate the distortion. However, if the distortion can be calculated independently of the other camera parameter, we can easily calibrate a camera without the need for a large number of calculations. Based on Tsai's camera model, we propose two different methods for calculating lens distortion. These methods are so simple and require so few calculations that the lens distortion can be rapidly calculated even in real-time applications. The first method is to refer to the focal length - lens distortion Look Up Table(LUT), which is constructed in the initialization process. The second method is to use the relationship between the feature points found in the image. Experiments were carried out for both methods, results of which show that the proposed methods are favorably comparable in performance with non-real full optimization method.

• KEPCO Journal on Electric Power and Energy
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• 제5권3호
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• pp.197-200
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• 2019

We report on electrochemical signal amplification using gap electrodes based on the redox cycling between gap electrodes. The distance between electrodes was controlled from $2{\mu}m$ to a few hundreds of nanometer by chemical deposition of reduced Au ion on the pre-defined electrodes. Enhanced redox current of ferri/ferrocyanide was obtained by redox cycling between the two working electrodes. The faradaic current is amplified about a thousand times in this redox system. Since the signal amplification is due to the shortened diffusion length between the two electrodes, the narrower the nanogap was, the better detection limit, calibration sensitivity, and dynamic range. The experimental results were discussed on the basis of the cyclic voltammetry (CV), atomic force microscope (AFM) and scanning electron microscope (SEM) measurements.

• Molecular & Cellular Toxicology
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• 제5권1호
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• pp.14-22
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• 2009

In vitro cytotoxicity of 23 alkyl phenols (APs) on human cervical cancer cell lines (HeLa) was determined using the lactate dehydrogenase (LDH) cytotoxicity assay. Two different sets of descriptors were used to construct the calibration model based on Genetic Algorithm-Multiple Linear Regression (GA-MLR) based on the experimental data. A statistically robust Structure-Activity Relationships (QSAR) model was achieved ($R^2$=95.05%, $Q^2_{LOO}$=91.23%, F=72.02 and SE= 0.046) using three Dragon descriptors based on Me (0D-Constitutional descriptor), BELp8 (2D-Burden eigenvalue descriptor) and HATS8p (3D-GETAWAY descriptor). However, external validation could not fully prove its validity of the selected QSAR in characterization of the cytotoxicity of APs towards HeLa cells. Nevertheless, the cytotoxicity profiles showed a finding that 4-n-octylphenol (4-NOP), 4-tert-octyl-phenol (4-TOP), 4-n-nonylphenol (4-NNP) had a more potent cytotoxic effect than other APs tested, inferring that increased length and molecular bulkiness of the substituent had important influence on the LDH cytotoxicity.

• 대한전자공학회논문지SD
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• 제43권12호
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• pp.55-64
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• 2006

본 설계에서는 무선 랜 등 최첨단 무선 통신 및 고급영상 처리 시스템과 같이 고해상도와 높은 신호처리속도, 저전력 및 소면적을 동시에 요구하는 고성능 집적시스템 응용을 위해 기존의 보정기법을 사용하지 않는 14b 70MS/s 0.13um CMOS A/D 변환기(Analog-to-Digital Converts- ADC)를 제안한다. 제안하는 がU는 중요한 커패시터 열에 인접신호에 덜 민감한 3차원 완전 대칭 구조의 레이아웃 기법으로 소자 부정합에 의한 영향을 최소화하였고, 3단 파이프라인 구조로 고해상도와 높은 신호처리속도와 함께 전력 소모 및 면적을 최적화하였다. 입력 단 SHA 회로에는 Nyquist 입력에서도 14비트 이상의 정확도로 신호를 샘플링하기 위해 게이트-부트스트래핑 (gate-bootstrapping) 회로를 적용함과 동시에 트랜스컨덕턴스 비율을 적절히 조정한 2단 증폭기를 사용하여 14비트에 필요한 높은 DC전압 이득을 얻음과 동시에 충분한 위상 여유를 갖도록 하였으며, 최종 단 6b flash ADC에는 6비트 정확도 구현을 위해 2단 오픈-루프 오프셋 샘플링 기법을 적용하였으며, 기준 전류 및 전압 발생기는 온-칩으로 집적하여 잡음을 최소화하면서 필요시 선택적으로 다른 크기의 기준 전압 값을 외부에서 인가할 수 있도록 하였다. 제안하는 시제품 ADC는 0.13um CMOS 공정으로 요구되는 2.5V 전원 전압 인가를 위해 최소 채널길이는 0.35um를 사용하여 제작되었으며, 측정된 DNL 및 INL은 14비트 해상도에서 각각 0.65LSB, 1.80LSB의 수준을 보이며, 70MS/s의 샘플링 속도에서 최대 SNDR 및 SFDR은 각각 66dB, 81dB를 보여준다. 시제품 ADC의 칩 면적은 $3.3mm^2$이며 전력 소모는 2.5V 전원 전압에서 235mW이다.

• 대한기계학회논문집A
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• 제32권10호
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• pp.844-849
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• 2008

We present a novel cell deformability monitoring chip based on the digitally measured cell lysis rate which is dependent on the areal strain of the cell membrane. This method offers simple cell deformability monitoring by automated high-throughput testing system. We suggest the filter design considering the areal strain imposed on the cell membrane passing through the filter array having gradually increased orifice length. In the experiment using erythrocytes, we characterized the cell deformability in terms of average fracture areal strain which was $0.24{\pm}0.014\;and\;0.21{\pm}0.002$ for normal and chemically treated erythrocytes, respectively. We also verified that the areal strain of 0.15 effectively discriminates the deformability difference of normal and chemically treated erythrocytes, which can be applied to the clinical situation. We compared the lysis rates and their difference for the samples from different donors and found that the present chips can be commonly used without any calibration process. The experimental results demonstrate the simple structure and high performance of the present cell deformability monitoring chips, applicable to simple and cost-effective cell aging process monitoring.