• Title/Summary/Keyword: least squares

Search Result 2,627, Processing Time 0.028 seconds

Application of Terahertz Spectroscopy and Imaging in the Diagnosis of Prostate Cancer

  • Zhang, Ping;Zhong, Shuncong;Zhang, Junxi;Ding, Jian;Liu, Zhenxiang;Huang, Yi;Zhou, Ning;Nsengiyumva, Walter;Zhang, Tianfu
    • Current Optics and Photonics
    • /
    • v.4 no.1
    • /
    • pp.31-43
    • /
    • 2020
  • The feasibility of the application of terahertz electromagnetic waves in the diagnosis of prostate cancer was examined. Four samples of incomplete cancerous prostatic paraffin-embedded tissues were examined using terahertz spectral imaging (TPI) system and the results obtained by comparing the absorption coefficient and refractive index of prostate tumor, normal prostate tissue and smooth muscle from one of the paraffin tissue masses examined were reported. Three hundred and sixty cases of absorption coefficients from one of the paraffin tissues examined were used as raw data to classify these three tissues using the Principal Component Analysis (PCA) and Least Squares Support Vector Machine (LS-SVM). An excellent classification with an accuracy of 92.22% in the prediction set was achieved. Using the distribution information of THz reflection signal intensity from sample surface and absorption coefficient of the sample, an attempt was made to use the TPI system to identify the boundaries of the different tissues involved (prostate tumors, normal and smooth muscles). The location of three identified regions in the terahertz images (frequency domain slice absorption coefficient imaging, 1.2 THz) were compared with those obtained from the histopathologic examination. The tissue tumor region had a distinctively visible color and could well be distinguished from other tissue regions in terahertz images. Results indicate that a THz spectroscopy imaging system can be efficiently used in conjunction with the proposed advanced computer-based mathematical analysis method to identify tumor regions in the paraffin tissue mass of prostate cancer.

The Crystal and Molecular Structure of (dl)-2-Benzyl-4-ethylester-5-(p-methylphenyl)-3H,5H,6H-1,2,6-thiadiazine-1,1-dioxide, $C_{20}H_{22}N_2O_4S$ ((dl)-2-Benzyl-4-ethylester-5-(p-methylphenyl)-3H,5H,6H-1,2,6-thiadiazine-1,1-dioxide, $C_{20}H_{22}N_2O_4S$의 結晶 및 分子構造)

  • Shin, Hyun-So;Kim, Euisung;Song, Hyun;Lee, Chai-Ho
    • Journal of the Korean Chemical Society
    • /
    • v.39 no.5
    • /
    • pp.344-349
    • /
    • 1995
  • The crystal and molecular structure of the title compound has been determined from 2568 reflections collected on an automatic CAD4 diffractometer using graphite-monochromated $Mo-K\alpha$ radiation. The crystal is monoclinic system, space group $P2_1$ with unit cell dimensions $a=8.756(8)\AA$, $b=25.757(2)\AA$, $c=8.628(1)\AA$, $\beta=99.15(4)^{\circ}$, V= 1,921(2) ${\AA}^3$, Z=4, $D_C=1.336\;g/cm^3$, ${\mu}=1.54\;cm^{-1}\;and\;T=298^{\circ}K$. The final R factor was 0.051 for 2049 reflections over $3{\sigma}(Fο).$ The crystal has two asymmetric molecules in the unit cell. The arrangement of sulfon group was shown a distorted tetrahedron structure and N(6), N(6') atoms were deviated from the least-squares planes of the thiadiazine rings, respectively. The molecular packings in the unit cell are linked by the two intermolecular hydrogen bonds of N-H---O type and van der Waals forces.

  • PDF

The Mediating Effects of the Manufacturing Capability and the Testing and Inspection Capability on the Relation between Small and Medium Venture Firms' External Information Network Heterogeneity and Technology Commercialization Capability (제조 역량과 시험 및 검사 역량이 중소벤처기업의 외부 정보 네트워크의 다양성과 기술 사업화 역량 사이의 관계에 미치는 매개 효과)

  • Hau, Yong Sauk
    • Journal of Digital Convergence
    • /
    • v.15 no.10
    • /
    • pp.233-241
    • /
    • 2017
  • This study has attempted to empirically analyze the mediating effects of small and medium venture firms' manufacturing capability and testing and inspection capability on the relation between their external information network heterogeneity and technology commercialization capability with a view to diversifying the research stream on the influential factors to small and medium firms' technology commercialization capability. By performing the ordinary least squares regression analysis, the Sobel test, and the Baron and Kenny test based on the 683 data of South Korean small and medium venture firms with the IBM SPSS version 23, this study provides the three empirical findings to be useful for future studies on the roles of small and medium venture firms' the manufacturing capability and testing and inspection capability. First, small and medium venture firms' manufacturing capability partially mediates the positive effect of their external information network heterogeneity on their technology commercialization capability. Second, their testing and inspection capability partially mediates this positive effect. Third, their manufacturing capability and testing and inspection capability jointly and partially mediates this positive effect.

Mean Square Projection Error Gradient-based Variable Forgetting Factor FAPI Algorithm (평균 제곱 투영 오차의 기울기에 기반한 가변 망각 인자 FAPI 알고리즘)

  • Seo, YoungKwang;Shin, Jong-Woo;Seo, Won-Gi;Kim, Hyoung-Nam
    • Journal of the Institute of Electronics and Information Engineers
    • /
    • v.51 no.5
    • /
    • pp.177-187
    • /
    • 2014
  • This paper proposes a fast subspace tracking methods, which is called GVFF FAPI, based on FAPI (Fast Approximated Power Iteration) method and GVFF RLS (Gradient-based Variable Forgetting Factor Recursive Lease Squares). Since the conventional FAPI uses a constant forgetting factor for estimating covariance matrix of source signals, it has difficulty in applying to non-stationary environments such as continuously changing DOAs of source signals. To overcome the drawback of conventioanl FAPI method, the GVFF FAPI uses the gradient-based variable forgetting factor derived from an improved means square error (MSE) analysis of RLS. In order to achieve the decreased subspace error in non-stationary environments, the GVFF-FAPI algorithm used an improved forgetting factor updating equation that can produce a fast decreasing forgetting factor when the gradient is positive and a slowly increasing forgetting factor when the gradient is negative. Our numerical simulations show that GVFF-FAPI algorithm offers lower subspace error and RMSE (Root Mean Square Error) of tracked DOAs of source signals than conventional FAPI based MUSIC (MUltiple SIgnal Classification).

Measurement of Solubilities in the Ternary System NaCl + CaCl2 + H2O and KCl + CaCl2 + H2O at 50℃ (NaCl + CaCl2 + H2O 및 KCl + CaCl2 + H2O 삼성분계에 대한 50℃에서의 용해도 측정)

  • Yang, Ji-Min;Hou, Guang-Yue;Ding, Tian-Rong;Kou, Peng
    • Journal of the Korean Chemical Society
    • /
    • v.54 no.3
    • /
    • pp.269-274
    • /
    • 2010
  • The solubility and the physicochemical property (refractive index) in the NaCl-$CaCl_2$-$H_2O$ and KCl-$CaCl_2$-$H_2O$ systems were determined at $50^{\circ}C$ and the phase diagrams and the diagrams of physicochemical property vs composition were plotted. One invariant point, two univariant curves, and two crystallization zones, corresponding to sodium Chloride (or potassium chloride), dihydrate ($CaCl_2{\cdot}2H_2O$) showed up in the phase diagrams of the ternary systems. The mixing parameters ${\theta}_{M,Ca}$ and ${\Psi}_{M,Ca,Cl}$ (M = Na or K) and equilibrium constant $K_{sp}$ were evaluated in NaCl-$CaCl_2-H_2O$ and KCl-$CaCl_2-H_2O$ systems by least-squares optimization procedure, in which the single-salt Pitzer parameters of NaCl, KCl and $CaCl_2$ ${\beta}^{(0)}$, ${\beta}^{(1)}$, ${\beta}^{(2)}$ and $C^{\Phi}$ were directly calculated from the literature. The results obtained were in good agreement with the experimental data.

The Influence of Dynamic Capabilities on the Competitive Capabilities and Performance of Export Venture Firms in Korea (기업의 동태적 역량이 경쟁능력 및 기업성과에 미치는 영향)

  • Hwang, Kyung-Yun;Sung, Eul-Hyun;Cho, Dae-Woo
    • Management & Information Systems Review
    • /
    • v.37 no.1
    • /
    • pp.19-40
    • /
    • 2018
  • The purpose of this study is to analyze the effects of a firm's dynamic capabilities measured by sensing, seizing, transforming, coordinating, and learning capabilities on its competitive capabilities, such as product quality, process flexibility, delivery speed, and low cost. The relationship among dynamic capabilities, competitive capabilities, and export firm performance is set up as a research model based on empirical studies related to the existing dynamic capability perspective and competitive capabilities. To test this research model, this study collected 102 samples of data using a questionnaire survey on both manufacturing and exporting firms. The partial least squares method is used and the following results are derived from an empirical analysis. First, dynamic capabilities have a positive effect on competitive capabilities, such as product quality, process flexibility, delivery speed, and low cost. Second, product quality and process flexibility have a positive effect on export firm performance. Third, unlike previous research results, this study finds that the competitive capabilities of a firm in the areas of delivery speed and low cost do not significantly affect its performance. These findings provide meaningful implications for export venture firms that need to acquire and maintain competitive advantage in a rapidly changing environment.

Site Characterization using Shear-Wave Velocities Inverted from Rayleigh-Wave Dispersion in Wonju, Korea (레일리파 분산을 역산하여 구한 횡파속도를 이용한 원주시의 부지특성)

  • Kim, Chungho;Ali, Abid;Kim, Ki Young
    • Geophysics and Geophysical Exploration
    • /
    • v.17 no.1
    • /
    • pp.11-20
    • /
    • 2014
  • To reveal shear-wave velocities ($v_s$) and site characterization of Wonju, Korea, Rayleigh waves were recorded at 78 sites of lower altitude using 12 to 24 4.5-Hz vertical geophones for 20 days during the period of February to September 2013. Dispersion curves of the Rayleigh waves obtained by the extended spatial autocorrelation method were inverted using the damped least-squares method to derive $v_s$ models. From these 1-D models, the average $v_s$ to a depth of 30 m ($v_s30$), $v_s$ of weathered rocks, depths to these basement rocks, and average $v_s$ of the overburden layer were derived to be $16.3{\pm}0.7m$, $576{\pm}8m/s$, $290{\pm}7m/s$, and $418{\pm}13m/s$, respectively, in the 95% confidence range. To determine adequate proxies for $v_s30$, we computed correlation coefficients of $v_s30$ with topographic slope (r = 0.46) and elevation (r = 0.43). An empirical linear relationship is presented as a combination of individually estimated $v_s30$ with weighting factors of 0.45, 0.45, and 0.1 for topographic slope, elevation, and mapped lithology, respectively. Due to a weak correlation between $v_s30$ obtained from inversion of dispersion curves and the proxy-based estimation (r = 0.50), however, the relatively large error range should be considered for applications of this relationship.

Improved deformation energy for enhancing the visual quality of planar shape deformation (평면 형상 변형의 시각적 품질 향상을 위한 개선된 형상 변형 에너지)

  • Yoo, Kwangseok;Choi, Jung-Ju
    • Journal of the Korea Computer Graphics Society
    • /
    • v.18 no.4
    • /
    • pp.1-8
    • /
    • 2012
  • We present improved deformation energy to enhance the visual quality of a shape deformation technique, where we preserve the local structure of an input planar shape. The deformation energy, in general, consists of several constraints such as Laplacian coordinate constraint to preserve the quality of deformed silhouette edges, mean value coordinates and edge length constraints to preserve the quality of deformed internal shape, and user-specified position constraints to control the shape deformation. When the positions of user-specified vertices change, shape deformation techniques compute the positions of the other vertices by means of nonlinear least squares optimization to minimize the deformation energy. When a user-specified vertex changes its position rapidly, it is frequently observed that the visual quality of the deformed shape decrease rapidly, which is mainly caused by unnecessary enlargement of the Laplacian vectors and unnecessary change of the edge directions along the boundary of the shape. In this paper, we propose improved deformation energy by prohibiting the Laplacian and edge length constraints from changing unnecessarily. The proposed deformation energy incorporated with well-known optimization technique can enhance the visual quality of shape deformation along the silhouette and within the interior of the planar shape while sacrificing only a little execution time.

Estimating Interregional Trade Coefficient of Service Industry using the Gravity Model (중력모형을 이용한 서비스업의 지역간 교역계수 추정)

  • Yun, Kap-Sik;Kim, Jae-Koo
    • Journal of the Economic Geographical Society of Korea
    • /
    • v.13 no.3
    • /
    • pp.457-469
    • /
    • 2010
  • The study aims to estimate interregional trade coefficient of service industry using the gravity model. The gravity model has been widely used for prediction of the level of human interaction between two regions which is positively related to attraction of them and negatively related to the distance between them. To apply the gravity model for explaining the interregional trade flow of service industry, the choice of proper proxy variables which represent a dependent variable and independent variables is most important. However, the literature shows that there are few studies on this issue. Four models concerned to the choice of proxy variables are considered. Finally, this paper employs the least-squares regression analysis to test the model's goodness-of-fit, and suggests the most appropriate model based on the result from the analysis. The result shows that the interregional trade of service industry in regional input-output table developed by The Bank of Korea is desirable as a dependent variable, the service industry output of export region, the population of import region, and the spatial distance between regions are desirable as independent variables.

  • PDF

Numerical Simulation of Lithium-Ion Batteries for Electric Vehicles (전기 자동차용 리튬이온전지 개발을 위한 수치해석)

  • You, Suk-Beom;Jung, Joo-Sik;Cheong, Kyeong-Beom;Go, Joo-Young
    • Transactions of the Korean Society of Mechanical Engineers B
    • /
    • v.35 no.6
    • /
    • pp.649-656
    • /
    • 2011
  • A model for the numerical simulation of lithium-ion batteries (LIBs) is developed for use in battery cell design, with a view to improving the performances of such batteries. The model uses Newman-type electrochemical and transfer $theories^{(1,2)}$ to describe the behavior of the lithium-ion cell, together with the Levenberg-Marquardt optimization scheme to estimate the performance or design parameters in nonlinear problems. The mathematical model can provide an insight into the mechanism of LIB behavior during the charging/discharging process, and can therefore help to predict cell performance. Furthermore, by means of least-squares fitting to experimental discharge curves measured at room temperature, we were able to obtain the values of transport and kinetic parameters that are usually difficult to measure. By comparing the calculated data with the life-test discharge curves (SB LiMotive cell), we found that the capacity fade is strongly dependent on the decrease in the reaction area of active materials in the anode and cathode, as well as on the electrolyte diffusivity.