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Effects of time compression on auditory working memory and decision making process in normal hearing subjects (시간 압축이 청각 작업기억과 의사 결정 과정에 미치는 영향)

  • Lim, Dukhwan
    • The Journal of the Acoustical Society of Korea
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    • v.41 no.1
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    • pp.64-69
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    • 2022
  • Background music is presented simultaneously with target messages. The main content should be kept intact for some time to aid decision making process. The maintenance of this information requires auditory working memory. The temporal compression of background music may often adopted due to the limitation of the presentation time. In this study, auditory working memory and decision making proces were analyzed in terms of temporal compression ratios of the background music. A total of 37 subjects of early twenties joined the study. Selected products were categorized based on eigen values of multi-dimensional scaling. Four presentation conditions were cases with no background music, background music with no compression, background music with low compression, and background music high compression. Matched reponses were analyzed through repeated ANOVA. Results showed that the high involvement product required more working memory resources. However, the increased level of usage did not always lead to the corresponding changes in decision making process. This approach may be useful in analyzing the role of time compression and working memory in consumer behaviors.

Study on Inclusive Business of Social Enterprise: Focusing on the Cases of Public-Private Partnership (사회적 기업의 포용적 비즈니스 연구: 민-관 협력기반 사례를 중심으로)

  • Han, Joon Hye
    • Korean small business review
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    • v.43 no.1
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    • pp.107-129
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    • 2021
  • Inclusive business is a social business that is promoted with the aim of supporting the economic independence and quality of life of poor people in developing countries. Inclusive business is emerging as a new development cooperation method that can lead to development effects such as income generation and economic independence by engaging the poor, traditionally recognized as 'the target of aid' in terms of development cooperation, in market-based economic activities. This study considered how this inclusive business overcomes various barriers in the market for the poor in developing countries and generates social values and economic returns. To this end, based on previous studies, an analytical framework was established to analyze inclusive business models and business types. And based on the multiple case study method, 17 cases of inclusive business of social enterprises were selected to analyze the characteristics of their business models and the types of business. Through this study, characteristics of value proposition mechanisms, value creation mechanisms, and value securing mechanisms of inclusive business based on public-private cooperation were derived. Also, how these inclusive businesses create social and economic values for the poor were analyzed. The findings present theoretical and practical implications for an inclusive business model.

Characteristics of Measurement Errors due to Reflective Sheet Targets - Surveying for Sejong VLBI IVP Estimation (반사 타겟의 관측 오차 특성 분석 - 세종 VLBI IVP 결합 측량)

  • Hong, Chang-Ki;Bae, Tae-Suk
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.40 no.4
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    • pp.325-332
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    • 2022
  • Determination of VLBI IVP (Very Long Baseline Interferometry Invariant Point) position with high accuracy is required to compute local tie vectors between the space geodetic techniques. In general, reflective targets are attached on VLBI antenna and slant distances, horizontal and vertical angles are measured from the pillars. Then, adjustment computation is performed by using the mathematical model which connects measurements and unknown parameters. This indicates that the accuracy of the estimated solutions is affected by the accuracy of the measurements. One of issues in local tie surveying, however, is that the reflective targets are not in favorable condition, that is, the reflective sheet target cannot be perfectly aligned to the instrument perpendicularly. Deviation from the line of sight of an instrument may cause different type of measurement errors. This inherent limitation may lead to incorrect stochastic modeling for the measurements in adjustment computation procedures. In this study, error characteristics by measurement types and pillars are analyzed, respectively. The analysis on the studentized residuals is performed after adjustment computation. The normality of the residuals is tested and then equal variance test between the measurement types are performed. The results show that there are differences in variance according to the measurement types. Differences in variance between distances and angle measurements are observed when F-test is performed for the measurements from each pillar. Therefore, more detailed stochastic modeling is required for optimal solutions, especially in local tie survey.

Metabolic Signaling by Adipose Tissue Hormones in Obesity (비만에서 adipose tissue 호르몬에 의한 metabolic signaling)

  • Younghoon Jang
    • Journal of Life Science
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    • v.33 no.3
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    • pp.287-294
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    • 2023
  • Healthy adipose tissue is critical for preventing obesity by maintaining metabolic homeostasis. Adipose tissue plays an important role in energy homeostasis through glucose and lipid metabolism. Depending on nutritional status, adipose tissue expands to store lipids or can be consumed by lipolysis. The role of adipose tissue as an endocrine organ is emerging, and many studies have reported that there are various adipose tissue hormones that communicate with other organs and tissues through metabolic signaling. For example, leptin, a representative peptide hormone secreted from adipose tissues (adipokine), circulates and targets the central nervous system of the brain for appetite regression. Furthermore, adipocytes secrete inflammatory cytokines to target immune cells in adipose tissues. Not surprisingly, adipocytes can secrete fatty acid-derived hormones (lipokine) that bind to their specific receptors for paracrine and endocrine action. To understand organ crosstalk by adipose tissue hor- mones, specific metabolic signaling in adipocytes and other communicating cells should be defined. The dysfunction of metabolic signaling in adipocytes occurs in unhealthy adipose tissue in overweight and obese conditions. Therapy targeting novel adipose metabolic signaling could potentially lead to the development of an effective anti-obesity drug. This review summarizes the latest updates on adipose tissue hormone and metabolic signaling in terms of obesity and metabolic diseases.

Analysis of malachite green and leuco-malachite green in sea food (수산식품 중 말라카이트그린 및 류코말라카이트그린의 분석)

  • Choi, Dongmi;Hong, Soongun;Im, Moohyeog;Jeong, Jiyoon;Chang, Moonik;Park, Kunsang;Hong, Mooki;Woo, Gunjo
    • Analytical Science and Technology
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    • v.19 no.2
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    • pp.142-148
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    • 2006
  • To determine malachite green and leuco-malachite green residues in sea food, a liquid chromatographic method has been optimized. The target compounds were extracted in the homogenized edible tissues with a mixture of McIlvaine buffer-acetonitrile and partitioned against dichloromethane. After concentrating the lower layer, the resulting residues were re-dissolved in methanol and analyzed by the HPLC with visible detector at 620 nm using acetonitrile-acetate buffer. For the analysis of leuco-malachite green with malachite green simultaneously, post-column packed with lead(IV) oxide was used for oxidizing leuco-malachite green to malachite green. The correlation coefficients($r^2$) was 0.9989 for malachite green, and 0.9995 for leuco-malachite green. The limit of detection was 0.005 mg/kg for the combined of malachite green and leuco-malachite green at signal/noise${\geq}3$. The recovery rate was within a reliable range of 84~98% (CV 3~16%). Leuco-malachite green were detected in carp and crusian carp.

Applying the Multiple Cue Probability Learning to Consumer Learning

  • Ahn, Sowon;Kim, Juyoung;Ha, Young-Won
    • Asia Marketing Journal
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    • v.15 no.3
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    • pp.159-172
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    • 2013
  • In the present study, we apply the multiple cue probability learning (MCPL) paradigm to examine consumer learning from feedback in repeated trials. This paradigm is useful in investigating consumer learning, especially learning the relationships between the overall quality and attributes. With this paradigm, we can analyze what people learn from repeated trials by using the lens model, i.e., whether it is knowledge or consistency. In addition to introducing this paradigm, we aim to demonstrate that knowledge people gain from repeated trials with feedback is robust enough to weaken one of the most often examined contextual effects, the asymmetric dominance effect. The experiment consists of learning session and a choice task and stimuli are sport rafting boats with motor engines. During the learning session, the participants are shown an option with three attributes and are asked to evaluate its overall quality and type in a number between 0 and 100. Then an expert's evaluation, a number between 0 and 100, is provided as feedback. This trial is repeated fifteen times with different sets of attributes, which comprises one learning session. Depending on the conditions, the participants do one (low) or three (high) learning sessions or do not go through any learning session (no learning). After learning session, the participants then are provided with either a core or an extended choice set to make a choice to examine if learning from feedback would weaken the asymmetric dominance effect. The experiment uses a between-subjects experimental design (2 × 3; core set vs. extended set; no vs. low vs. high learning). The results show that the participants evaluate the overall qualities more accurately with learning. They learn the true trade-off rule between attributes (increase in knowledge) and become more consistent in their evaluations. Regarding the choice task, there is a significant decrease in the percentage of choosing the target option in the extended sets with learning, which clearly demonstrates that learning decreases the magnitude of the asymmetric dominance effect. However, these results are significant only when no learning condition is compared either to low or high learning condition. There is no significant result between low and high learning conditions, which may be due to fatigue or reflect the characteristics of learning curve. The present study introduces the MCPL paradigm in examining consumer learning and demonstrates that learning from feedback increases both knowledge and consistency and weakens the asymmetric dominance effect. The latter result may suggest that the previous demonstrations of the asymmetric dominance effect are somewhat exaggerated. In a single choice setting, people do not have enough information or experience about the stimuli, which may lead them to depend mostly on the contextual structure among options. In the future, more realistic stimuli and real experts' judgments can be used to increase the external validity of study results. In addition, consumers often learn through repeated choices in real consumer settings. Therefore, what consumers learn from feedback in repeated choices would be an interesting topic to investigate.

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Discovering the Anti-cancer Effects of Ligusticum Chuanxiong through Network-based Pharmacology Analysis and Molecular Docking: An Inquiry into Natural Products (네트워크 기반 약리학 분석 및 분자 도킹을 통한 천궁의 항암 효과 예측: 천연물에 대한 탐구)

  • Do Kyung Han;Jee Won Shon;Eui Suk Sung;Youn Sook Kim;Won G. An
    • Journal of Life Science
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    • v.33 no.11
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    • pp.876-886
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    • 2023
  • In some cases of head and neck cancers (HNC), surgical interventions may result in the loss of organs and/or changes to their functions, thereby significantly affecting the patient's quality of life. As a result, the surgical treatment of HNC patients is often limited to specific cases, and alternative treatment modalities, such as chemotherapy, are considered. However, serious adverse effects caused by chemotherapy, such as severe nausea and vomiting, necessitate the need for the development of adjunctive methods to minimize patient suffering. Chuanxiong, Ligusticum chuanxiong (L. chuanxiong), is a natural herb used in Eastern medicine to treat cerebrovascular disorders and headaches. This study aimed to predict the effect and potential of L. chuanxiong as an auxiliary anticancer drug through network-based pharmacology and molecular docking analysis. The study results showed that 40 out of 41 genes of L. chuanxiong shared common targets of HNC and their proteins could be used to target HNC cells to prevent cancer progression. The results of the functional enrichment analysis confirmed that L. chuanxiong is associated with the neuroactive-ligand metabolism and neurotransmitter pathways, indicating its potential medicinal value as an adjuvant in HNC treatment. Lastly, our findings demonstrated that the active ingredient of L. chuanxiong, (Z)-Ligustilide, has the ATP binding site of heat shock protein 90, a protein known to promote the activation of cancer cells. These results suggest that L. chuanxiong is a promising candidate for developing auxiliary anticancer drugs, and further research could potentially lead to the discovery of newer and safer anti-cancer agents.

Change in the Concrete Strength of Forest Road Drainage Systems Caused by Forest Fires (산불로 인한 임도 배수시설의 콘크리트 강도 변화)

  • Ye Jun Choe;Jin-Seong Hwang;Young-In Hwang;Hyeon-Jun Jeon;Hyeong-Keun Kweon;Joon-Woo Lee
    • Journal of Korean Society of Forest Science
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    • v.112 no.4
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    • pp.451-458
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    • 2023
  • As forest fires continue to increase in scale worldwide, the importance of forest roads in relation to forest fire prevention and suppression has become increasingly evident. To ensure effective functioning during a forest fire disaster, it is crucial to apply appropriate road planning and ensure roads' structural integrity. However, previous studies have predominantly focused on the impact of forest fires on firebreak efficacy and road placement, meaning that insufficient attention has been paid to ensuring the safety of these facilities. Therefore, this study sought to compare the strength of concrete facilities within areas damaged by forest fires over the past three years by using the rebound hammer test to identify signs of thermal degradation. The results revealed that concrete facilities damaged by forest fires exhibited significantly lower strength (15.6 MPa) when compared with undamaged facilities (18.0 MPa) (p<0.001), and this trend was consistent across all the target facilities. Consequently, it is recommended that safety assessment criteria for concrete forest road facilities be established to prevent secondary disasters following forest fire damage. Moreover, continuous monitoring and research involving indoor experiments are imperative in terms of enhancing the stability of forest road structures. It is expected that such research will lead to the development of more effective strategies for forest fire prevention and suppression.

Drought impact on water quality environment through linkage analysis with meteorological data in Gamcheon mid-basin (기상자료와의 연계분석을 통한 수질환경에 대한 가뭄영향 연구 - 감천중권역을 대상으로)

  • Jo, Bugeon;Lee, Sangung;Kim, Young Do;Lee, Joo-Heon
    • Journal of Korea Water Resources Association
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    • v.56 no.11
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    • pp.823-835
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    • 2023
  • Recently, due to the increase in abnormal climate, rainfall intensity is increasing and drought periods are continuing. These environmental changes lead to prolonged drought conditions and difficulties in real-time recognition. In general, drought can be judged by the amount of precipitation and the number of days without rainfall. In determining the impact of drought, it is divided into meteorological drought, agricultural drought, and hydrological drought and evaluation is made using the drought index, but environmental drought evaluation is insufficient. The river water quality managed through the total water pollution cap system is vulnerable to the effects of such drought. In this study, we aim to determine the drought impact on river water quality and quantify the impact of prolonged drought on water quality. The impact of rain-free days and accumulated precipitation on river water quality was quantitatively evaluated. The Load Duration Curve (LDC), which is used to evaluate the water quality of rivers, was used to evaluate water pollution occurring at specific times. It has been observed that when the number of consecutive rainless days exceeds 14 days, the target water quality in the mid-basin is exceeded in over 60% of cases. The cumulative rainfall is set at 28 days as the criteria, with an annual average rainfall of 3%, which is 32.1 mm or less. It has been noted that changes in water quality in rivers occur when there are 14 or more rainless days and the cumulative rainfall over 28 days is 32.1 mm or less in the Gamcheon Mid-basin. Based on the results of this study, it aims to quantify the drought impact and contribute to the development of a drought water quality index for future environmental droughts.

Comparison of Esophageal Cancer Radiation Therapy Plans Using Volumetric Modulated Arc Therapy (체적 조절 호형 방사선치료(VMAT)를 활용한 식도암 치료계획 비교)

  • Won-Young Jeong;Jae-Bok Han;Young-Hyun Seo;Jong-Nam Song
    • Journal of the Korean Society of Radiology
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    • v.18 no.3
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    • pp.249-256
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    • 2024
  • The study aimed to evaluate the efficacy of treatment plans using full Arc and Partial Arc Coplanar volumetric modulated arc therapy and Non-Coplanar volumetric modulated arc therapy to minimize radiation treatment side effects, such as pneumonia, and protect normal organs in esophageal cancer radiotherapy. 30 patients who underwent Concurrent Chemoradiotherapy for esophageal cancer were included. Compared planning target volume, lung, heart, spinal cord and total monitor units among three treatment plans: fVMAT(2 Full Arc), pVMAT(4 Partial Arc), and ncVMAT(2 Partial Arc + 2 Non-Coplanar Arc). All plans met the PTV criteria, showing uniform distribution. The average dose to the heart was 5.8 Gy for fVMAT, 6.97 Gy for pVMAT, and 7.6 Gy for ncVMAT, with the lowest value in fVMAT, which was statistically significant. However, the average lung dose was 9.01 Gy for fVMAT, 7.71 Gy for pVMAT, and 7.12 Gy for ncVMAT, with V5Gy(%) values of 52.22%, 38.61%, 36.35% and V10Gy(%) values of 37.8%, 27.33%, 24.15% respectively. ncVMAT showed the lowest values, while fVMAT had the highest, with statistical significance. In conclusion, ncVMAT effectively reduces lung radiation exposure in esophageal cancer radiotherapy, potentially reducing the incidence of side effects such as pneumonia. However, considering factors like setup accuracy and treatment time, applying an appropriate treatment plan may lead to better outcomes.