• The Korean Journal of Pain
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• 제30권3호
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• pp.197-206
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• 2017

Background: Pain with neuropathic characteristics is generally more severe and associated with a lower quality of life compared to nociceptive pain (NcP). Short form of the Douleur Neuropathique en 4 Questions (S-DN4) is one of the most used and reliable screening questionnaires and is reported to have good diagnostic properties. This study was aimed to cross-culturally validate the Hindi version of the S-DN4 in patients with various chronic pain conditions. Methods: The S-DN4 is already translated into the Hindi language by Mapi Research Trust. This study assessed the psychometric properties of the Hindi version of the S-DN4 including internal consistency and test-retest reliability after 3 days' post-baseline assessment. Diagnostic performance was also assessed. Results: One hundred sixty patients with chronic pain, 80 each in the neuropathic pain (NeP) present and NeP absent groups, were recruited. Patients with NeP present reported significantly higher S-DN4 scores in comparison to patients in the NeP absent group (mean (SD), 4.7 (1.7) vs. 1.8 (1.6), P < 0.01). The S-DN4 was found to have an AUC of 0.88 with adequate internal consistency (Cronbach's ${\alpha}=0.80$) and a test-retest reliability (ICC = 0.92) with an optimal cut-off value of 3 (Youden's index = 0.66, sensitivity and specificity of 88.7% and 77.5%). The diagnostic concordance rate between clinician diagnosis and the S-DN4 questionnaire was 83.1% (kappa = 0.66). Conclusions: Overall, the Hindi version of the S-DN4 has good internal consistency and test-retest reliability along with good diagnostic accuracy.

• 대한수의학회지
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• 제44권4호
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• pp.669-676
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• 2004

To evaluate the diagnostic accuracy of two commercial ELISA tests (Allied- and CSL-ELISA) for the diagnosis of Mycobacterium paratuberculosis in cattle, Meta-analysis using English language papers published during 1990-2001 was performed. Diagnostic odds ratios (DOR) were analyzed using regression analysis together with summary receiver operating characteristic (ROC) curves. The difference in diagnostic performance between the two ELISA systems was evaluated by using linear regression. Publication bias was assessed by funnel plot and linear regression. The pooled sensitivity and specificity were 44% (95% CI, 38 to 51) and 98% (95% CI, 96 to 99) for the random-effect model. The DOR between studies was heterogeneous. The area under the fitted ROC curve (AUC) was 0.72 for the unweighted and 0.77 for the weighted model. Maximum joint sensitivity and specificity for the unweighted and weighted model from their summary ROC curve were 70% and 75%, respectively. Based on the fitted model, at a specificity of 95%, sensitivity was estimated to be 52% for the unweighted and 57% for the weighted model. From the final multivariable model study characteristic, the country was the only significant variable with an explained component variance of 13.3%. There were no significant differences in discriminatory power, sensitivity, and specificity between the two ELISA tests. The overall diagnostic accuracy of two commercial ELISA tests was moderate, as judged by the AUC, maximum joint sensitivity and specificity, and estimates from the fitted model and clinical usefulness of the tests for screening program is limited because of low sensitivity and heterogeneous of DOR. It is, therefore, recommended to use ELISA tests as a parallel testing with other diagnostic tests together to increase test sensitivity in the screening program.

• 대한치매학회지
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• 제23권3호
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• pp.117-126
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• 2024

Background and Purpose: The Korean-Mini Mental State Examination, 2nd edition (K-MMSE~2) was recently released. This study aimed to determine whether the K-MMSE~2: Standard Version (K-MMSE~2:SV) had the same test characteristics as the K-MMSE. Methods: A total of 1,514 healthy community-based participants aged 19 to 90 years were administered the K-MMSE~2:SV Blue Form along with the language items from the K-MMSE. The item and test characteristics and test information for the K-MMSE~2:SV and K-MMSE were compared using Item Response Theory analysis. Results: Item discriminations for the K-MMSE~2:SV and K-MMSE were above the moderate range for all items except Recall. Most of the items on the K-MMSE~2:SV and K-MMSE had item category difficulty in the very easy or easy range. The test information curve (TIC) showed that the K-MMSE~2:SV and K-MMSE provide almost the same amount of information (27.86 vs. 28.44), with both tests providing the most information at an ability level of -1.57. The generalizability (G) coefficient for the K-MMSE~2:SV and K-MMSE was 0.99. Conclusions: These results indicate that the K-MMSE~2:SV and K-MMSE are equally optimal tests for screening for mild cognitive impairment and early dementia. Given that the amount of test information provided by the two tests was almost identical, the shapes of the TICs were very similar, and the G coefficient was close to 1, we can conclude that the K-MMSE and K-MMSE~2:SV are equivalent tests.

• 한국융합학회논문지
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• 제12권3호
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• pp.297-304
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• 2021

이 연구는 학령기 아동의 발달지원을 위하여 기존의 미술 치료 및 교육에서 시행되어 온 시각적 사고 중심의 접근에 더하여, 언어 교육 및 치료적 접근을 융합하고자 한 것이다. 이에 언어와 미술의 서로 다른 영역의 융합 가능 영역을 탐색하기 위하여 텍스트 마이닝 기법을 적용하였다. 이에 따라 이 연구는 기초 연구, 예비 DB구축, 텍스트 선별, DB 전 처리 및 확정, 불용어 처리, 텍스트 마이닝 분석 및 융합 가능 역 도출'의 절차에 따라 연구를 진행하였다. 연구 결과, 미술 치료 및 교육과 언어 치료 및 교육 분야에서 나타나는 문헌상의 각 군집을 연계하여 의사소통 및 학습 기능, 문제해결 및 감각 기관, 예술 및 지능, 정보와 의사소통, 가정 및 장애, 주제와 개념화 및 또래, 통합과 재구성 및 태도 등과 관련된 융합역을 도출할 수 있었다. 결론적으로 본 연구를 통하여 향후 미술과 언어의 활동 중심 융합형 프로그램을 설계할 수 있는 프레임워크를 마련하고 아동발달 지원을 위한 총체적 접근을 시도하였다는 점에서 연구의 의의가 있다.

• 대한한방내과학회지
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• 제39권2호
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• pp.139-146
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• 2018

Objective: The purpose of this clinical study is to report the effect of Banhahoobak-tang in the case of a 57-year-old woman with multiple cerebral infarction causing dysphagia and dysarthria diagnosed as pseudobulbar palsy. Methods: A patient was treated with Korean medicine, including herbal medication, acupuncture, and language therapy. We focused on the effect of Banhahoobak-tang by evaluating improvements in symptoms by examining times of aspiration and changes in Speech Mechanism Screening Test scores. Results: After three months of Korean medicine treatment and language therapy, there was improvement in the patient's symptoms, including dysphagia and dysarthria. Conclusions: This study suggests that Korean medicine treatment could be effective for improving the symptoms of pseudobulbar palsy in patients. Specifically, herbal medicine (Banhahoobak-tang) could be an effective choice for treating dysphagia.

• 한국융합학회논문지
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• 제11권5호
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• pp.153-158
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• 2020

본 연구는 정상 노인과 초기 단계의 노년기 인지 장애(경도인지장애(MCI), 경도 치매)의 선별검사인 대면 이름대기와 범주 이름대기의 예측력을 파악하였다. 노년기 인지장애로 진단을 받은 340명(정상 노인 203명, MCI 106명, 경도 치매 31명)을 분석하였다. 대면 이름대기는 단축형 한국판 보스턴 이름대기 검사로 측정하였고, 범주 이름대기는 통제연상단어검사의 의미검사와 음소검사를 이용하여 측정하였다. 이름대기 검사의 예측 성능을 비교하고자 다항 로지스틱 회귀분석을 수행한 결과, 대면 이름대기와 범주 이름대기 검사 모두 일반노인에서 MCI와 경도 치매를 감별하는데 유의미한 효과가 확인되었다(p<0.05). 반면, MCI에서 경도 치매를 감별할 때, 범주 이름대기의 음소검사는 교차비가 유의미하지 않았다. 본 연구의 결과는 MCI에서 경도 치매를 감별할 때, 범주 이름대기의 총점만을 측정기준으로 분석하는 것은 유의하지 않을 가능성이 높음을 시사한다.

• 대한한방내과학회지
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• 제39권6호
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• pp.1105-1115
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• 2018

Objectives: The aim of this review is to investigate clinical studies on Oriental medicine treatment for aphasia after cerebrovascular disease. Methods: Using the keywords 'Aphasia', 'Oriental medicine', 'Stroke' 'Cerebral infarction', 'Cerebral hemorrhage', and 'Clinic', we searched domestic databases, including "NDSL (National Discovery for Science Leaders)", "Korean Traditional Knowledge Portal", "OASIS (Oriental Medicine Advanced Searching Integrated System)", and "RISS (Research Information Sharing Service)". Each keyword was not searched individually, but combined in various ways. To investigate recent trends, we limited our search to papers published after 2000. Papers that did not include a specific treatment method or did not match the subject "Aphasia after stroke" were excluded. Results: Using the searching method, 13 studies were found. Of these, 12 studies were in the form of case reports, while one was in the form of a non-randomized controlled trial. These studies showed positive results for the use of Oriental medicine in terms of the Korean version of the Western Aphasia Battery (K-WAB), the evaluation form on functional performance capability and accuracy of articulatory organs developed by Lee, aphasia screening test refered in 'Assessment in Speech-Language Pathology' and adapted properly to Korean, the Communicative Ability in Daily Living Test (CADLT), the Korean Version-Boston Naming Test (K-BNT), and language assessment items included in CNS, and NIHSS. Conclusions: Of the 12 case reports, 11 studies showed positive results of the use of Oriental medicine for treatment of aphasia after cerebrovascular disease. However, more sophisticated and large-scale clinical research on aphasia should be conducted.

• 대한통합의학회지
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• 제7권3호
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• pp.51-59
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• 2019

Purpose : To evaluate the effect of comprehensive art therapy on physical function and activities of daily living in children with cerebral palsy (CP). Methods : Ten ambulant children with diplegic (n=8) or hemiplegic (n=2) CP participated in this study. All were randomly assigned to either the art therapy group (n=5) or the control group (n=5). Both groups received physical therapy based on neurodevelopmental techniques for 20 minutes a day, 1 day a week, for a period of 12 weeks. Children in the art therapy group received additional comprehensive art therapy for 70 minutes once a week for 3 months. Tests for various measurements-Motricity Index (MI) for strength, Trunk Control Test (TCT) for trunk ability, Gross Motor Function Measure (GMFM) and Gross Motor Function Classification System (GMFCS) for gross motor function, Denver Developmental Screening Test-II (DDST-II) for developmental milestones, Functional Independence Measure of Children (WeeFIM) for abilities to complete daily activities, Leg and Hand Ability Test (LHAT) for limb function-were performed before and after treatments. Results : The upper extremity and whole extremity strengths of MI, self-care and total scores of WeeFIM, and leg and arm functions of LHAT improved significantly only for individuals in the art therapy group after the art therapy (p<.05). The value of MI after treatment was at the upper extremity and whole extremity strengths the leg function of LHAT was also significantly improved compared to the control group (p<.05). Conclusion : This study revealed that comprehensive art therapy along with physiotherapy was effective in increasing upper extremity strength and leg ability in children with CP. This suggests that comprehensive art therapy may be a useful adjunctive therapy for children with CP.

• 정보관리학회지
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• 제36권3호
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• pp.131-148
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• 2019

본 연구는 시청자가 사운드 자료의 주제를 파악하는 과정과 사운드의 특성을 이해하기 위한 인지적 정보처리 모형을 구성하였다. 이후 사건관련유발전위(event related potentials, ERP)의 두뇌의 전후측에 걸쳐서 발현하는 N400, P600 구성요소들을 인지적 정보처리 모형의 언어적 표상에 접목시켜 사운드 요약을 생성하는 방안을 제안하기 위해서 연구 가설들을 수립하였다. 뇌파 실험을 통해서 연구 가설들을 검증한 결과, P600이 사운드 요약의 핵심 구성 요소로 나타났다. 본 연구 결과는 분류 알고리즘 설계에 적용되어 내용 기반 메타데이터 즉, 일반적인 또는 개인화된 미디어 요약(사운드 요약, 비디오 스킴)을 생성하는 데에 활용될 수 있을 것이다.

• Journal of Audiology & Otology
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• 제24권3호
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• pp.133-139
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• 2020

Background and Objectives: The Gaps-In-Noise (GIN) test is a clinically effective measure of the integrity of the central auditory nervous system. The GIN procedure can be applied to a pediatric population above 7 years of age. The present study conducted the GIN test to compare the abilities of auditory temporal resolution among typically developing children, children with speech sound disorder (SSD), and children with cognitive difficulty (CD). Subjects and Methods: Children aged 8 to 11 years-(total n=30) participated in this study. There were 10 children in each of the following three groups: typically developing children, children with SSD, and children with CD. The Urimal Test of Articulation and Phonology was conducted as a clinical assessment of the children's articulation and phonology. The Korean version of the Wechsler Intelligence Scale for Children-III (K-WISC-III) was administered as a screening test for general cognitive function. According to the procedure of Musiek, the pre-recorded stimuli of the GIN test were presented at 50 dB SL. The results were scored by the approximated threshold and the overall percent correct score (%). Results: All the typically developing children had normal auditory temporal resolution based on the clinical cutoff criteria of the GIN test. The children with SSD or CD had significantly reduced gap detection performance compared to age-matched typically developing children. The children's intelligence score measured by the K-WISC-III test explained 37% of the variance in the percent-correct score. Conclusions: Children with SSD or CD exhibited poorer ability to resolve rapid temporal acoustic cues over time compared to the age-matched typically developing children. The ability to detect a brief temporal gap embedded in a stimulus may be related to the general cognitive ability or phonological processing.