• Title/Summary/Keyword: lack of fit

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Detection of Mendelian and Parent-of-origin Quantitative Trait Loci for Meat Quality in a Cross between Korean Native Pig and Landrace

  • Choi, B.H.;Lee, Y.M.;Alam, M.;Lee, J.H.;Kim, T.H.;Kim, K.S.;Kim, J.J.
    • Asian-Australasian Journal of Animal Sciences
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    • v.24 no.12
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    • pp.1644-1650
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    • 2011
  • This study was conducted to detect quantitative trait loci (QTL) affecting meat quality in an $F_2$ reference population of Korean native pig and Landrace crossbreds. The three-generation mapping population was generated with 411 progeny from 38 $F_2$ full-sib families, and 133 genetic markers were used to produce a sex-average map of the 17 autosomes. The data set was analyzed using least squares Mendelian and parent-of-origin interval-mapping models. Lack-of-fit tests between models were used to characterize the QTL for mode of gene expressions. A total of 10 (32) QTL were detected at the 5% genome (chromosome)-wise level for the analyzed traits. Of the 42 QTL detected, 13 QTL were classified as Mendelian, 10 as paternal, 14 as maternal, and 5 as partial expressed QTL, respectively. Among the QTL detected at 5% genome-wise level, four QTL had Mendelian mode of inheritance on SSCs 5, 10, 12, and 13 for cooking loss, drip loss, crude lipid and crude protein, respectively; two QTL maternal inheritance for pH at 24-h and shear force on SSC11; three QTL paternal inheritance for CIE b and Hunter b on SSC9 and for cooking loss on SSC15; and one QTL partial expression for crude ash on SSC13, respectively. Most of the Mendelian QTL (9 of 13) had a dominant mode of gene action, suggesting potential utilization of heterosis for genetic improvement of meat quality within the cross population via marker-assisted selection.

Detection of Mendelian and Parent-of-origin Quantitative Trait Loci in a Cross between Korean Native Pig and Landrace I. Growth and Body Composition Traits

  • Kim, E.H.;Choi, B.H.;Kim, K.S.;Lee, C.K.;Cho, B.W.;Kim, T.-H.;Kim, J.-J.
    • Asian-Australasian Journal of Animal Sciences
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    • v.20 no.5
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    • pp.669-676
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    • 2007
  • This study was conducted to detect quantitative trait loci (QTL) affecting growth and body composition in an $F_2$ reference population of Korean native pig and Landrace crossbreds. The three-generation mapping population was generated with 411 progeny from 38 $F_2$ full-sib families, and 133 genetic markers were used to produce a sex-average map of the 18 autosomes. The data set was analyzed using least squares Mendelian and parent-of-origin interval-mapping models. Lack-of-fit tests between the models were used to characterize QTL for mode of expressions. A total of 8 (39) QTL were detected at the 5% genome (chromosome)-wise level for the 17 analyzed traits. Of the 47 QTL detected, 21 QTL were classified as Mendelian expressed, 13 QTL as paternally expressed, 6 QTL as maternally expressed, and 7 QTL as partially expressed. Of the detected QTL at 5% genome-wise level, two QTL had Mendelian mode of inheritance on SSC6 and SSC9 for backfat thickness and bone weight, respectively, two QTL were maternally expressed for leather weight and front leg weight on SSC6 and SSC12, respectively, one QTL was paternally expressed for birth weight on SSC4, and three QTL were partially expressed for hot carcass weight and rear leg weight on SSC6, and bone weight on SSC13. Many of the Mendelian QTL had a dominant (complete or overdominant) mode of gene action, and only a few of the QTL were primarily additive, which reflects that heterosis for growth is appreciable in a cross between Korean native pig and Landrace. Our results indicate that alternate breed alleles of growth and body composition QTL are segregating between the two breeds, which could be utilized for genetic improvement of growth via marker-assisted selection.

Relationship Between Perceived Risk and Physician Recommendation and Repeat Mammography in the Female Population in Tehran, Iran

  • Moshki, Mahdi;Taymoori, Parvaneh;Khodamoradi, Sahmireh;Roshani, Daem
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.sup3
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    • pp.161-166
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    • 2016
  • Iranian women are at high risk of low compliance with repeat mammography due to a lack of awareness about breast cancer, negative previous experiences, cultural beliefs, and no regular visits to a physician. Thus research is needed to explore factors associated with repeated mammography participation. Applying the concept of perceived risk as the guiding model, this study aimed to test the fit and strength of the relationship between perceived risk and physician recommendation in explaining repeat mammography. A total of 601 women, aged 50 years and older referred to mammography centers in region 6, were recruited via a convenience sampling method. Using path analysis, family history of breast cancer and other types of cancer were modeled as antecedent perceived risk, and physician recommendation and knowledge were modeled as an antecedent of the number of mammography visits. The model explained 49% of the variance in repeat mammography. The two factors of physician recommendation and breast self-examination had significant direct effects (P < 0.05) on repeat mammography. Perceived risk, knowledge, and family history of breast cancer had significant indirect effects on repeat mammography through physician recommendation. The results of this study provide a background for further research and interventions not only on Iranian women but also on similar cultural groups and immigrants who have been neglected to date in the mammography literature.

Case Study on Measuring Technology Level Applying Growth Curve Model: Three Core Areas of Fishery Science and Technology (성장곡선 모형 적용을 통한 기술수준평가 사례 연구 : 특정 수산과학기술 분야를 중심으로)

  • Kim, Wan-Min;Park, Ju-Chan;Bark, Pyeng-Mu
    • The Journal of Fisheries Business Administration
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    • v.46 no.3
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    • pp.103-118
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    • 2015
  • The purpose of this paper is to discuss possibilities of applying growth curve models, such as Logistic, Log-Logistic, Log-Normal, Gompertz and Weibull, to three specific technology areas of Fishery Science and Technology in the process of measuring their technology level between Korea and countries with the state-of-the art level. Technology areas of hazard control of organism, environment restoration, and fish cluster detect were selected for this study. Expert panel survey was conducted to construct relevant panel data for years of 2013, 2016, and a future time of approaching the theoretical maximum technology level. The size of data was 70, 70 and 40 respectively. First finding is that estimation of shape and location parameters of each model was statistically significant, and lack-of-fit test using estimated parameters was statistically rejected for each model, meaning all models were good enough to apply for measuring technology levels. Second, three models other than Pearl and Gompertz seemed very appropriate to apply despite the fact that previous case studies have used only Gompertz and Pearl. This study suggests that Weibull model would be a very valid candidate for the purpose. Third, fish cluster detect technology level is relatively higher for both Korea and a country with the state-of-the-art among three areas as of 2013. However, all three areas seem to be approaching their limits(highest technology level point) until 2020 for countries with the state-of-the-art. This implies that Korea might have to speed up her research activities in order to catch up them prior to 2020. Final suggestion is that future study may better apply various and more appropriate models respectively considering each technology characteristics and other factors.

Can parents prevent tooth loss related to dental avulsion? An assessment of knowledge related to permanent teeth

  • Gowri Sivaramakrishnan;Deena Abawi;Fatima Mohammad Shoaib;Fatema Bucheery;Ahmed Ali Salman;Majeed Jasim Kadhem;Fatema AlSulaiti;Muneera Alsobaiei ;Leena AlSalihi
    • Journal of Trauma and Injury
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    • v.36 no.1
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    • pp.15-21
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    • 2023
  • Purpose: Dental avulsion injuries have a poor prognosis that largely depends on the immediate steps taken to manage the avulsed tooth. A lack of knowledge about the initial management can lead to tooth loss, with further adverse implications for esthetics, phonetics, and overall growth and function. Hence, the present study aimed to assess parents' knowledge regarding dental avulsion and the variables associated with their knowledge of avulsion injuries. Methods: A series of closed-ended questions on parents' knowledge regarding avulsion, such as immediate management, storage media, handling, and urgency of visiting the dentist, was asked. Univariate associations between the outcomes were assessed using the Pearson chi-square test. The chisquare goodness-of-fit test was used to check whether the sample data were representative of the population. Results: In total, 211 mothers and 149 fathers were included, of whom 46.7% had experienced dental trauma during their own childhood. Sixty-one percent of mothers believed that they knew everything necessary about tooth avulsion and its management. A significant number of participants who thought that they had a good level of knowledge about avulsion chose water, tissue, or paper wrap to transport the tooth, and preferred tap water, alcohol, or antiseptic to clean the avulsed tooth. Conclusions: Both mothers and fathers had poor knowledge about tooth avulsion, indicating that there is an immediate need for educational programs focusing on this issue. Since a substantial proportion of participants believed incorrect information, it is vital to disseminate accurate information.

Children's Wear Design Considering Physical Changes of Children and Fashion Preferences of Children and Parents (신체 변화 및 패션 취향분석을 고려한 여자 아동복 디자인)

  • Park, Judy Joo-Hee;Nam, Yun-Ja
    • Journal of the Korean Society of Clothing and Textiles
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    • v.33 no.4
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    • pp.598-610
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    • 2009
  • The aim of this study was to present a flexible and satisfactory clothing design for girls aged 4 to 6 years of age, which can be worn comfortably for 3 years, during that age range. This study focuses attention on the need for well-fitting clothes in the young girls' market, and provides a basis for development of designs that can be worn for a long time, are comfortable for children to wear, and reflect preferences of both children and parents. Documentary research was executed to examine the history and changes of children's wear. Internet and market research were carried out to understand the current situation of girls' clothing in Korea. In-depth interview subjects were girls aged 4 to 6 and their guardians. Subjects were asked questions related to children's wear size and design, and measurements were taken of child subjects. Children's wear on the Internet was found to be trendy and inexpensive but of a low quality, as was children's wear at Dongdaemun market. Children's wear at department stores was of high quality and pretty, but did not consider size much and was expensive. One problem of the Korean children's wear market was lack of a unified size system. In-depth interviewees pointed out that there are not many clothes that fit their children perfectly. Problems included t-shirt, sleeve and pants length. Parents said they preferred simple and clean designs, and children interviewees all liked pink dresses and skirts. Children's physical measurements presented by Size Korea were compared and verified with measurements taken of child interviewees, and used as a basis for patterns. The study presented two designs for girls of ages 4 to 6 to wear all through that age range. A sample was made for one of the designs, and an evaluation showed very successful results.

Analyzing Tableware Arrangement in Korean Table Settings (한식상차림의 식기배치 분석)

  • Kim, Hyewon;Lee, Hyeran;Cho, Wookyoun
    • Journal of the Korean Society of Food Culture
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    • v.28 no.1
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    • pp.31-40
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    • 2013
  • The purpose of this study is to analyze external elements of 'time series table serving' and to discover any problems in the table setting. We selected two traditional Korean restaurants in five-star hotels and two representative traditional Korean style restaurants and analyzed the tableware arrangement of their table settings. The results are as follows. In restaurant A, the arrangement of different styles of tableware made from a variety of materials seemed relatively natural. However, the dessert plates were 'Buncheong' ware made with 'Bakji' method; in this case, the pattern was larger than the size of the fruits served and made the food inconspicuous. Rather than using plates made with a 'bakji' method, using plates with small patterns in the 'johwa' method would complement the food. In restaurant B, the space between the tableware, spoon and chopsticks was narrow, and the spoon and chopsticks sets would not fit on the table pads when large dishes or multiple dishes were served. In this case, changing the dishes to smaller sized dishes, considering the size of the table pad, or not using the pad at all would solve the issue. In restaurant C, too many small dishes were laid on the table, making it look disorderly. We believe that recovering tableware that is no longer in use, laying dishes and cutlery inside of the table pads or not using the table pad would be better. In restaurant D, the same style and color of dishes were provided 9 times. The lack of variety could be tedious to customers. The forms and colors of dishes should be changed in accordance with the order of the meal served. However, when using tableware created by different methods such as 'Buncheong' ware or white porcelain, the same pattern should be chosen in order to elevate the dignity of the table menu through uniformity. These issues in tableware arrangement indicate that external forms of banquet table setup should be studied so that the culture of Korean traditional cuisine can be enriched.

Effect of anatomic, semi-anatomic and non-anatomic occlusal surface tooth preparations on the adaptation of zirconia copings

  • Habib, Syed Rashid;Asiri, Waleed;Hefne, Mohammed Jameel
    • The Journal of Advanced Prosthodontics
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    • v.6 no.6
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    • pp.444-450
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    • 2014
  • PURPOSE. To compare the accuracy of marginal and internal adaptation of zirconia (Zr) copings fabricated on anatomic (A), semi-anatomic (SA) and non-anatomic (NA) occlusal surface preparations. MATERIALS AND METHODS. 45 extracted bicuspid teeth were prepared for receiving zirconia crowns, with different occlusal preparation designs A=15, SA=15 & NA=15. The Zr copings were fabricated by using CAD4DENT, CAD/CAM. The copings were adjusted, cemented and were cross sectioned centrally from buccal cusp tip to lingual cusp tip into mesial and distal halves. The copings were examined under electron microscope at ${\times}200$ magnification and the measurements were recorded at 9 predetermined areas in micrometers. RESULTS. Overall mean gap values for the three groups was found to be $155.93{\pm}33.98{\mu}m$ with Anatomical Occlusal preparation design having the least gap value of $139.23{\pm}30.85{\mu}m$ showing the best adaptation among the groups. Post Hoc Tukey's test showed a statistically significant difference (P=.007) between the means of gap for A & NA preparation designs. Measurements recorded at 9 predetermined points showed variations for the three groups. CONCLUSION. Anatomical occlusal preparation designs resulted in better marginal and internal adaptation of Zr copings. There is a considerable variation between the measured marginal and internal gap values for the Zr copings fabricated by the (CAD4DENT-CAD/CAM). This variation may be associated with the lack of standardization of the preparation of teeth, computerized designing of the coping for each tooth, cement used, uniform pressure application during the cementation of the copings, sectioning of the copings and the microscopic measurements.

The Effect of Trial-Experience Information on the Traffic and Sales Performance of Apparel Product Websites (인터넷 쇼핑몰에서 의류상품에 대한 착의경험 정보제공이 트래픽과 판매성과에 미치는 영향)

  • Kim Tae-Youn;Lee Yoon-Jung
    • Journal of the Korean Society of Clothing and Textiles
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    • v.29 no.11
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    • pp.1369-1380
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    • 2005
  • This study suggests a strategy of providing apparel product information from the wearers' perspective on Internet shopping malls, as a way of compensating for the lack of opportunities to try on the actual product. On an actual Internet shopping mall that sells apparel product, the 'trial-experience information' (the experiential information provided by the fit models who tried on the products) was provided for 83 different items from four women's wear brands. The traffic and sales performances (number of visitors, page view, gross sales of goods, conversion rate, and the numbers of customer transactions) of the apparel product websites that contain trial-experience information were compared to the performances of the brand's websites before this information was implemented. The changes in percent contribution of these brands in women's wear category were also noted. The specific results are as follows: First, all the four performance measures as well as the percent contribution of the experiment products in women's wear category increased noticeably throughout the experiment period (11 to $103\%$). Second, when the percent contribution of these brands in women's wear category in terms of traffic and sales performances were compared to the previous year, these measures increased between $497\%\;and\;2851\%$. Third, the amount of customer transactions also increased after the trial-information was provided, yet to a relatively smaller extent $(29.04\%\;to\;55.25\%)$. The findings showed that trial-experience information provided on the Internet shopping malls may reduce customers' risk perception and lead to increased sales of apparel product and improve the site use ratio.

Impact of waste crumb rubber on concrete performance incorporating silica fume and fly ash to make a sustainable low carbon concrete

  • Muhammad, Akbar;Zahoor, Hussain;Pan, Huali;Muhammad, Imran;Blessen Skariah, Thomas
    • Structural Engineering and Mechanics
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    • v.85 no.2
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    • pp.275-287
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    • 2023
  • The use of environmental-friendly building materials is becoming increasingly popular worldwide. Compared to the normal concrete, rubber-based concrete is considered more durable, environmentally friendly, socially and economically viable. In this investigation, M20 grade concrete was designed and the fine aggregates were replaced with crumb rubber of two different micron sizes (0.221 mm and 0.350 mm). Fly ash (FA) and silica fume (SF) replaces the binder as supplementary cementitious materials at a rate of 0, 5, 10, 15, and 20% by weight. The mechanical properties of concrete including compressive strength, tensile, and flexural strength were determined. The polynomial work expectation validates the response surface approach (RSM) concept for optimizing SF and FA substitution. The maximum compressive strength (22.53 MPa) can be observed for the concrete containing 10% crumb rubber, 15% fly ash and 15% silica fume. The reduced unit weight of the rubberized concrete may be attributed to the lower specific gravity of the rubber particles. Two-way ANOVA with a significance criterion of less than 0.001 has been utilized with modest residual error from the lack of fit and the pure error. The predictive model accurately forecasts the variable-response relationship. Since, the crumb rubber is obtained from wasted tires incorporating FA and SF as a cementitious ingredient, it helps to significantly improve mechanical properties of concrete and reduce environmental degradation.