• Title/Summary/Keyword: korea traditional prescription

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A Look into the Changes in Medical Activities during the Late Chosun Dynasty Period through Hajae's Diary (『하재일기』를 통해 본 구한말 의약생활의 변화)

  • Lee, Jeong-Hyeon
    • Journal of Korean Medical classics
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    • v.27 no.4
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    • pp.39-53
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    • 2014
  • Objectives : Hajae's Diary(荷齋日記) is a personal diary written by Gyu-Sik Ji(池圭植) between 1891 and 1911. He had a strong interest in medicine and maintained the belief that diseases could be cured by medicine. He recorded in significant detail the subject individuals, symptoms, name of prescription, price, the date of exchange and place of purchase in his diary. Methods : His study classifies the era during which Western medicine was introduced to the general public and became popularized in the late Chosun dynasty period based on articles related to medicine in Hajae's Diary. Results : It could be identified that, as of the Gabo Reform(甲午更張) in 1894, Western medicine was introduced into the traditional medicine life and, starting from the Eulsa Treaty(乙巳條約) of 1905, Western medicine became popularized. Conclusions : During the "traditional medicine period", traditional medicine was used for all medicinal activities. However, during the "Western medicine introduction period", Western medicine was used for only specific diseases. In the period during which Western medicine became popular, traditional medicine continued to be used. However, Western medicine was widely used for various diseases.

The Radioprotective Effect of Kuei-Pi-Tang as a prescription of Traditional Chinese Medicine in Mice (생쥐에서 귀비탕 및 구성단미의 방사선 방호효과)

  • Kim, Sung-Ho;Lee, Song-Eun;Oh, Heon;Yang, Jung-Ah;Chung, Chi-Young;Jang, Jong-Sik;Yu, Young-Beob;Jo, Sung-Kee
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.28 no.3
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    • pp.698-704
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    • 1999
  • In this study, we evaluated the radioprotective effects of Kuei Pi Tang and its ingredients, as a prescription of traditional Oriental medicine. The jejunal crypt survival, endogenous spleen colony formation, and apoptosis in jejunal crypt cells were investigated in mice irradiated with high and low dose of ${\gamma}$ rays. In the mice administered with Kuei Pi Tang extract before irradiation, the jejunal crypts were protected significantly(p<0.005) and the frequency of radiation induced apoptosis was reduced(p<0.05). In the experiment on the effects of the ingredients of Kuei Pi Tang, the results indicated that the extract of Dangui(Angelica sinensis), Suanzaoren(Zizyphus valgaris), Rensan (Panax ginseng), Fuling(Poria cocos) and Muxiang(Saussurea lappa) might have a major radioprotective effect. Although the mechanisms of this inhibitory effect remain to be elucidated, these results indi cated that Kuei Pi Tang might be a useful radioprotector, especially since it is a relatively nontoxic natural product.

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The Effects of Shi-Quan-Dai-Bu-Tang and Its Ingredients on the Survival of Jejunal Crypt Cells and Hematopoietic Cells in Irradiated Mice (방사선 피폭 마우스에서 소장움세포 및 조혈세포 생존에 미치는 십전대보탕 및 구성단미의 영향)

  • Jo, Sung-Kee;Yu, Young-Bub;Oh, Heon;Kim, Se-Ra;Kim, Sung-Ho
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.29 no.1
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    • pp.93-98
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    • 2000
  • We performed this study to determine the radioprotective effects of Shi-Quan-Dai-Bu-Tang, as a prescription of traditional Oriental medicine, and its major ingredients. The jejunal crypt survival, endogenous spleen colony formation, and apoptosis in jejunal crypt cells were investigated in mice irradiated with high and low dose of ${\gamma}$-rays. The administration of danggui, baishaoyao, rensan, gancao or baifuling before irradiation protected the jejunal crypts (p<0.005). Shoudehuang, danggui, baishaoyao, rensan and huangqui increased the formation of endogenous spleen colony (p<0.05). Chuanxiong, baishaoyao, rensan and baifuling reduced the frequency of radiation-induced apotosis (p<0.05). The results indicated that the extracts of danggui, baishaoyao, rensan and baifuling may have radoprotective effects in mice irradiated with high and low dose of ${\gamma}$-rays. The radioprotective effect of the prescription, Shi-Qaun-Da-Bu-Tang, was not significant.

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The Comparative Study of Oriental Medicine in Korea, Japan and China (한국(韓國)과 일본(日本) 및 중국(中國)의 동양의학(東洋醫學)에 대한 비교연구(比較硏究))

  • Cho, Ki-Ho
    • The Journal of Korean Medicine
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    • v.19 no.1
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    • pp.271-298
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    • 1998
  • During these days of new understanding, western medicine has developed remarkably and a revaluation of traditional medicine has been achieved. This appears to have resulted from the sound criticisms of what western medicine has achieved up to now; excessive subdivisions of clinical medicine, severe toxicity of chemical drugs, lack of understanding about patients complaints which cannot be understood objectively, and etc. It is thought that the role of traditional medicine will be more important in the future than it is now. Someone said that the research methods of traditional medicine depends on the way of experimental science too much. That there was no consideration of a system for traditional medicine and the critic also went so far as to assert that in some cases the characteristics of eastern ideas is to permit irrationalism itself. In view of this thinking, the term traditional medicine seems to have been used somewhat too vaguely. However, traditional medicine is a medical treatment which has existed since before the appearance of modern medicine and it was formed from a traditional culture with a long history. One form of traditional medicine, oriental medicine based upon ancient Chinese medicine, was received in such countries as Korea, Japan, Thailand, Vietnam, Tibet, and Mongolia. Oriental medicine then developed in accordance with its own environment, race, national characteristics, and history. Although there are some simultaneous differences between them, three nations in Eastern Asia; Korea, Japan, and China, have especially similar features in their clinical prescriptions and medical literature. These three nations are trying to understand each others unique traditional medicines through numerous exchanges. Even though many differences in their ways of studying have developed over history exist, recent academic discussions have been made to explore new ways into oriental medicine. Therefore a comparative study of oriental medicine has gradually been thought to be more important. In Korea the formation of a new future-oriented paradigm for oriental medicine is being demanded. The purpose of the new paradigm is to create a new recognition of traditional culture which creates an understanding of oriental medicine to replace the diminished understanding of oriental medicine that was brought about by the self-denial of traditional culture in modem history and cultural collisions between oriental and occidental points of view. Therefore, to make a new paradigm for oriental medicine which is suitable for these days, and fortifies the merit of oriental medicine while compensating its defects, the author has compared the characteristics of oriental medicines in Korea, Japan, and China. The conclusions of this research are as follows: 1. The fundamental differences of the traditional medicines of these three nations are caused by the differences in the systems of Naekyung and Sanghannon. 2. The pattern-identification of illnesses is generally divided into two categories; the pattern identification of Zang-Fu and the pattern identification of prescription. 3. There are many differences in the definition of terms, such as Yin and Yang, Deficiency and Excess, and etc. 4. Chinese traditional medicine has some new concepts about pattern identification and epidemic febrile disease. 5. Japanese traditional medicine has some characteristics about pattern identification of the whole bodys condition and signs of abdominal palpation. 6. In terms of the effects of herbal drugs, Chinese traditional medicine attaches great importance to the experiential efficacy of the herb, and Japanese traditional medicine is taking a serious view of the effects of experimental medical actions.

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An experimental study for the development of prescription on atopic dermatitis (아토피 피부염 외치치료제 처방 개발을 위한 실험적 연구)

  • Kim, Gun Woo;Bak, Ji Won;Sim, Boo-Yong;Kim, Dong Hee
    • The Korea Journal of Herbology
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    • v.29 no.4
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    • pp.13-20
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    • 2014
  • Objectives : Atotang was composed of 10 kinds of traditional medicinal herb. This research was performed to examine biological effects of Atotang for the development of prescription on atopic dermatitis. Methods : Atotang was extracted with 80% EtOH. Free radical scavenging assay has tested for anti-oxidative activity as well as the contents of total polyphenol. We observed the production of ROS, nitric oxide(NO) and the inflammatory cytokines such as interleukin-1beta(IL-${\beta}$), IL-6, tumor necrosis factor-alpha(TNF-${\alpha}$), Prostaglandin E2($PGE_2$) in Raw 264.7 cells stimulated by LPS. We used Disc diffusion method to investigate antibacterial activity on Candida albicans, Staphylococcus aureus and Staphylococcus epidermis. Result : Content of total phenolic compound of Atotang was 36.3 mg/g ext. DPPH and ABTS scavenging activities were 77% and 46% at 200 ug/ml respectively, showing dose-dependent increase. The amounts of ROS and NO in RAW 264.7 cells were decreased by 30% and 19% at 200 ug/ml, respectively, showing dose-dependent decrease. The prodcution of IL-1beta, IL-6 and TNF-alpha in RAW 264.7 cells were decreased dose-dependently by 81%, 67%, and 20% at 200 ug/ml, respectively. Atotang was reduced LPS-stimulated production of $PGE_2$ by 33%. Atotang on C. albicans, S. aureus and S. epidermis was selected by a disc diffusion method and inhibition effect of the Atotang on the growth of S. epidermis was the greatest. Conclusion : The results indicated that Atotang showed biological activities showing anti-oxidant, anti-inflammatory and antibacterial effects. Based on these results, it is concluded that Atotang can be applied to the prescription on atopic dermatitis.

Cytotoxic Effect of Korean Traditional Prescriptions on the Human Gastric Cancer Cell Lines (한약처방제의 인체 위암 세포주에 대한 세포독성 효과에 관한 연구)

  • Kim, Eun-Hae;Eun, Young-Ah;Kang, Bong-Joo;Sung, Hyun-Jae;Park, Kap-Joo
    • Korean Journal of Pharmacognosy
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    • v.28 no.4
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    • pp.233-238
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    • 1997
  • ln order to search for antigastric cancer agents from Korean traditional prescriptions. We selected 41 traditional prescriptions, based on a review of the Korean traditional medicine books. Both boiling water and methanol extracts were tested, by means of the Sulforhodamine B (SRB) protein assay. Six of the 41 water extracts; #3, #34, #35, #38, #40, #41 showed efficacy against gastric cancer cell (AGS: Human gastric carcinoma, ATCC HTB 103). #3 inhibited 50% cancer cell growth1 at the concentration of $152\;{\mu}g/ml$, #34, #35, #38, #40 and #41 inhibited 50% cancer cell growth at the concentration of $145\;{\mu}g/ml$, $129\;{\mu}g/ml$, $173\;{\mu}g/ml$, $10\;{\mu}g/ml$ and $19\;{\mu}g/ml$ respectively. Ten of the 41 methanol extracts; #1, #3, #32, #33, #35, #36, #37, #38, #41 were active. #1 inhibited 50% cancer cell growth at the concentration of $206\;{\mu}g/ml$, #3, #32, #33, #35, #36, #37, 738, #40, #41 inhibited 50% cancer cell growth at the concentration of $133\;{\mu}g/ml$, $159\;{\mu}g/ml$, $199\;{\mu}g/ml$, $147\;{\mu}g/ml$, $113\;{\mu}g/ml$, $187\;{\mu}g/ml$, $130\;{\mu}g/ml$, $9\;{\mu}g/ml$, $15\;{\mu}g/ml$ respectively. Prescription #3, #35, #38, #40, #41 were also interesting because both methanol and water extracts were active.

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KAP Study on Oriental Traditional Doctor, Hospital and Medicine in Korea (최근 일부 한국이의 한의사.한방의료기관 및 한의학 관련 인식 태도 및 의료행위에 관한 연구)

  • Lee Sun-Dong;Park Kyong-Sik
    • Journal of Society of Preventive Korean Medicine
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    • v.1 no.1
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    • pp.27-41
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    • 1997
  • The degree of KAP study on oriental traditional medicine was examined with some korean from July 1st to August 30th in 1996. The result of the study for predicting health and ill patterns runs as fellows. 1) It is too weak to understand and adertise oriental traditional medicine doctors and the curable disease; moreover cured diseases rather preponderate. 2) Although most patients go to oriental traditional medical clinic for the purpose of medical herbs in package and acupuncture, they think the medical fee a high expensive. 3) The 77.9% of respondents recognize oriental traditional medical doctors as a profession and others think them only abundant workers; therefore it is rather low to think oriental traditional doctors a profession. 4) Most respondents ink that oriental traditional medicine should improved in the inside; such as the expensive fee, scientific reinforcement of theory, lack of univerality, improvement and enlargement of insurance, unkindness, shortage of publicity, dropped equipment, system of medical specialist, lack of integration with western medicine, exact diagnosis and confidence of remedy and low efficacy, etc. 5) The struggle against the government (1995-1996 about herbal prescription right by western pharmacy) has taken the change of affirmative recognition. 6) The degree that acknowleges of oriental traditional medicine through these basic contents is average 61.65 mark. To be brief, although the step of recognition and attitude of oriental me야cine is very affirmative aspect, actually considerable difficult factors is in the last chosen step.

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Beakdugu-tang, Traditional Korean Digestant Medicine, Inhibits Hepatic Steatosis in Insulin Resistance Cell Model with HepG2 and THP-1

  • Kim, Hyuck;Lim, Dong-Woo;Park, Sung Yun;Park, Sun-Dong;Park, Won-Hwan;Kim, Jai-Eun
    • The Journal of Korean Medicine
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    • v.38 no.2
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    • pp.53-60
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    • 2017
  • Objectives: Beakdugu-tang (BDGT) consists of three medicinal herbs, and this prescription has long been used in treatment of various digestant problem in Korea. In this study, we designed to clarify mechanisms by which Korean traditional digestive medicine, BDGT, may exert anti-hepatic steatosis effects via improved insulin resistance cell model in human hepatocellular carcinoma (HepG2) and monocyte (THP-1). Materials and methods: The preparation of BDGT and constituents were extracted with 70% ethanol. HepG2 and THP-1 were treated with different concentrations of BDGT and constituents in the presence and absence of stimulants such as free fatty acids (FFAs) and oxidized low-density lipoprotein (ox-LDL), respectively. Results: The BDGT and its constituents inhibited the FFAs-stimulated lipid accumulation in HepG2 cells. Ethanol extracts of Amomum cardamomum (ACE) improved the ox-LDL induced insulin resistance in THP-1 cells. Also, treatment of monocytic cells with ACE increased anti-hepatic steatosis related gene levels including ABCA, ABCG and SR-B1. Conclusion: The results suggest that the ethanol extract of BDGT and its constituents potently inhibit the FFAs- and ox-LDL induced liver steatosis via improved insulin resistance.

Prevention effect of Sunkiwhajung-tang, a prescription, on the gastric ulcer induced by indomethacin in rats (순기화중탕이 Indomethacin으로 유발된 위궤양에 미치는 영향)

  • Kim Sang Chan;Lee Dong En;Kwon Young Kyu
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.17 no.2
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    • pp.326-337
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    • 2003
  • In order to evaluate the prevention effect of Sunkiwhajung-tang (SWT) which has been used as a traditional prescription for the treatment of digestive disease in Korea on the gastric ulcer induced by indomethacin in rats, the changes of number and size of ulcerative lesions, parietal, chief, Grimelius and Serotonin-positive cells in the peri-ulcerative tissues were detected with histological examinations of ulcerative and peri-ulcerative lesions after oral injections of SWT extracts (125, 250 and 500 mg/kg, respectively). SWT prevented to a great extent the expected indomethacin-induced elevation in hemorrhagic ulcerative lesions, the number and size of ulcerative lesions, and the number of parietal cell, chief cell, Grimelius-positive cells and Serotonin-positive cells in the peri-ulcerative lesions in a dose dependent manner. These results provide a story evidence that SWT produced an protective effect on gastric ulcer induced by indomethacin. Determination of the specific mechanisms involved in the protective effect of SWT on the gastric ulcer will require additional study.

A Review on Prescriptions for Mouth and Teeth in 「Throat, Mouth and Teeth」 of 『Yuyaoyuanfang』 (『어약원방(御藥院方)』 「인후구치문(咽喉口齒門)」 중 치아질환 처방에 관한 고찰)

  • Shin, Jae-Hyuck;Song, Ji-Chung;Maeng, Hak-Young;Eom, Dong-Myung
    • The Journal of Korean Medical History
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    • v.25 no.1
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    • pp.81-91
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    • 2012
  • Objectives : "Yayaoyuanfang" is a prescription book, compiled by Xuguozhen in 1267. In "Yayaoyuanfang", there are 13 chapters including "Throat, Mouth and Teeth". Because there are few prescription books focused only on mouth and teeth disease in traditional medicine, "Throat, Mouth and Teeth" in "Yayaoyuanfang" is distinctive. Methods : We try to analyze prescriptions by form, effectiveness and report experiences in "Yayaoyuanfang". Results : There are 95 prescriptions with 77 powder, 5 paste, 5 liquid, 2 granule and 5 other forms. Effectiveness of those are divided into teeth, gum and mouth. Effectiveness for teeth are about pains, weakness, cavity, discoloration and so on. Effectiveness for gum are about pain, swelling, weakness, shrinking, etc. Effectiveness for mouth is about bad breath. Conclusions : "Throat, Mouth and Teeth" in "Yayaoyuanfang" has professional prscriptions for throat, mouth and teeth with several form and effectiveness.