The Jindo dog is a Korean natural monument and is recognized by the Fédération Cynologique Internationale. A prominent feature is the diverse coat color within the breed. To analyze the genetic basis of variation in the Jindo coat color, we sequenced the protein-coding regions of the melanocortin 1 receptor gene (MC1R). The MC1R coding sequence was determined from 154 dogs in five breeds (Jindo, Labrador Retriever, English Springer Spaniel, Belgian Malinois, and German Shepherd). To confirm the genetic structure of sampled populations, we tested for Hardy-Weinberg equilibrium (HWE) and computed $F_{st}$ The sample populations did not significantly deviate from HWE. $F_{st}$ was 0.02 between white and fawn Jindo dogs; this was lower than $F_{st}$ between breeds. Six single nucleotide polymorphisms (SNPs) were detected in the MC1R coding region. Among the six SNPs, five were non-synonymous (S90G, T105A, Q159P, M264V, and R306ter) and one was synonymous SNP (Y298Y). From the SNPs, we predicted four haplotypes (H1, H2, H3, and H4) for Jindo MC1R. Jindo dogs had different haplotypes corresponding to different coat colors. H1 was frequently observed in white Jindo dogs with an odds ratio of 5.03 (95% CI: 2.27-11.18, p<0.0001), whereas H2 and H4 were observed only in fawn Jindo dogs. Our findings indicate that SNP haplotype can influence coat color. Knowledge of MC1R haplotypes can help discriminate white and fawn coats in Jindo dogs. We hope this report will trigger more research into the genetics of this traditional Korean dog and will be a reference for dogs of Asian origin. Also, our results will provide a useful genetic marker for Jindo dog breeders who have selected for specific colors.
Journal of the Korean Regional Science Association
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v.6
no.2
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pp.123-147
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1990
This paper examines the changing geography of producer service industries in the 1980s. The foci of this study are to analyze the regional distribution of each producer services, and to reveal the spatial linkage of producer services. Further this paper asserts the potential role of producer services for reducing the potential endogenous development in the periphery. During the 1981-86 period, producer service industries grew more rapidly than other service sectors and manufacturing sector. The main reason of the raid growth of producer services is attributable to an increase in demand for intermediate services from manufacturing firms. In order to compete an increasingly complex business environment, firms have expanded the amount of effort devoted to activities such as planning, coordination and control, and consequently have increased their use of producer services. The most distinctive feature of the location of producer services is spatial concentration into Seoul and surrounding region. Especially the degree of the concentration o business services into the Capital Region has been accelerating during the 1990s. The pattern of employment growth and regional distribution of producer services show a clear core / periphery disparity. Much of the regional inequality in producer services is largely due to variation in demand associated with the pattern of corporation headquarters with the pattern of corporation headquarters and branch plants location with large manufacturing firms. The analysis of spatial division of labor reflects that producer services are related to the location of headquarters in manufacturing industry. Headquarters in manufacturing firms and business service firms tend to cluster each other. Most of the headquarters spatially separated from branch offices are clustered heavily in Seoul. Especially headquarters of business services and insurance services are overwhelmingly concentrated into Seoul. The firms whose headquarters are located in Seoul have a linkage pattern on a nationwide scale. It is viewed have little potential for generating local multiplier effects and regional development. In the light of the result of this study, producer services are not likely to disperse soon to peripheral regions. Consequently the absence of policies directed at enhancing producer sevice in the periphery, concentration tendency would continue to reinforce the core's dominance at the expense of peripheral regions. From a regional perspective, the quality of a region's producer service sector is a key determinant of economic growth, since manu industrial location decisions are influenced by the differential availability of producer services among regions. Poor performance of producer services in peripheral regions seemed to be linked to the region's manufacturing base. Low-wage, standardized branch plants are not likely to induce the growth in knowledge intensive services associated with high-technology corporate headquarters. Producer services may help to create and attract new business including manufacturing firms, and also to enhance the productivity and competitiveness of local firms. Therefore the provision of service producing activities would be lead not only to generate and retain endogenous development but also to attract external firms, especially small and medium sized firms which have a lower propensity of internalized services. Hence, it may be more efficient to create and expanse new locally owned producer services rather than to attract branch plants of mult-locational firms in order to make indigenous economic development.
KSCE Journal of Civil and Environmental Engineering Research
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v.3
no.3
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pp.1-7
/
1983
In spite of extensive knowledge of the surface chemistry and the transport mechanism in filtration systems, there is still insufficient understanding of the physical characteristics of suspensions and the system components. Because of this, no filtration mechanisms are mathematically generalized to the full extent. The purpose of this paper is to propose experimental equations for the filtration process. using the tracer study in filter layer. Some of results are as follows. (1) The Volume of the specific deposit (${\sigma}$) in filtration was directly measurable using the tracer study without interrupting the filtration. (2) It was also confirmed that the head loss in filtration was greatly in fluenced by the micro-air babbles. (3) The correction coefficient(f) was introduced into the Kozeny-Carman equation in order to apply it for the clogging filter media. The coefficient(f) was experimentally obtained. The total head loss of the filter media is given by next equation. $${\frac{h}{h_0}}={\frac{1}{L}}{\int}^{z=L}_{z=0}f({\sigma})g({\varepsilon}_0,{\sigma})dz$$$$f=aexp(-b{\sigma})$$ The above equation was applicable without regard to the variation of the suspension concentration, the filter medium diameter, the filter depth, the filtration velocity, and the amount of aluminum in all continuous filtration experiments. (4) The total head loss was graphically generalized assuming mathematical filtration models I II (see fig. 7,8) (5) The total head loss was obtained from the filtration model in the field filtration conditions. (see fig. 9,10)
Proceedings of the Korean Society of Crop Science Conference
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2017.06a
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pp.239-239
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2017
The enhancement of leaf photosynthetic capacity can have the potential to improve the seed yield of soybean. Key targets for the increase of leaf photosynthetic capacity remains unclear in soybean. Peking, Chinese local variety, has been the useful material for soybean breeding since it shows various resistances against biotic and abiotic stress. Sakoda et al., 2017 reported that Peking had the higher capacity of leaf photosynthesis than Enrei, Japanese elite cultivar. They identified the genetic factors related to high photosynthetic capacity of Peking. The objective of this study is to elucidate the physiological basis underlying high photosynthetic capacity of Peking. Peking and Enrei were cultivated at the experimental field of the Graduate School of Agriculture, Kyoto University, Kyoto, Japan. The sowing date was July 4, 2016. Gas exchange parameters were evaluated at the uppermost fully expanded leaves on 43, 49, and 59 days after planting (DAP) with a portable gas exchange system, LI-6400. The leaf hydraulic conductance, $K_{leaf}$, was determined based on the water potential and transpiration rate of the uppermost fully expanded leaves on 60 DAP. The morphological traits related to leaf photosynthesis were analyzed at the same leaves with the gas exchange measurements. The light-saturated $CO_2$ assimilation rate ($A_{sat}$) of Peking was significantly higher than that of Enrei at 43 and 59 DAP while the stomatal conductance ($g_s$) of Peking was significantly higher at all the measurements (p < 0.05). It suggested that high $A_{sat}$ was mainly attributed to high $g_s$ in Peking. $g_s$ is reported to be affected by the morphological traits and water status inside the leaf, represented by $K_{leaf}$, in crop plants. The tendency of the variation of the stomatal density between two cultivars was not consistent throughout the measurements. On the other hand, $K_{leaf}$ of Peking was 59.0% higher than that of Enrei on 60 DAP. These results imply that high $g_s$ might be attributed to high $K_{leaf}$ in Peking. Further research is needed to reveal the mechanism to archive high $g_s$ on the basis of water physiology in Peking. The knowledge combining the genetic and physiological basis underlying high photosynthetic capacity of Peking can be useful to improve the biomass productivity of soybean.
Objective: The purpose of this study was to look at a systematic review on the relationships of saccadic eye movements and cognition. Through this comprehensive study, we have to compare the studies. Methods: We systematically examined papers published in journal from 1995 to 2015, using KERIS. Main words to examine are saccadic eye movements, cognitive function, cognition, relationship, saccade program, etc. Results: 6 studies were selected, All of them were saccadic eye movements. Eye movements and cognitive function have correlation. Age from 5 to 65 years from the studies, they found the relationships between cognition and saccade(p<.05). However, the results demonstrated some limitations. First, there were variation in large of age spectrum. Second, the populations were small. Therefore, in the future study, saccadic eye movements study apply to variety of interventions to separate experimental group and control group as cohort study, and majority of patients is needed on occupational therapy. Conclusions: In the future study, the use of eye movements apply to a variety of interventions and majority of patients is needed for the effect of cognitive function improvements. If occupational therapists can obtain knowledge and make a protocol for cognitive program.
Background: The global burden of cancer is continuously increasing. According to recent report of the National Cancer Registry Programme (NCRP) on time trends it is estimated that future burden of cancer cases for India in 2020 will be 1,320,928. It is well known that knowledge of the incidence of cancer is a fundamental requirement of rational planning and monitoring of cancer control programs. It would help health planners to formulate public health policy if relevant ethnic groups were considered. North East-India alone contains over 160 Scheduled Tribes and 400 other sub-tribal communities and groups, whose cancer incidence rates are high compared to mainland India. As since no previous study was done focusing on ethnicity, the present investigation was performed. Materials and Methods: In this paper PBCR-Guwahati data on all cancer registrations from January 2009 to December 2011 for residents of the Kamrup Urban District, comprising an area of 261.8 sq. km with a total population of 900,518, including individual records with information on sex, age, ethnicity and cancer site are provided. Descriptive statistics including age adjusted rates (AARs) were taken as provided by NCRP. For comparison of proportional incidence ratios (PIR) the Student's t test was used, with p<0.05 considered as statistically significant. Results and Conclusions: Differences in leading sites of Kamrup Urban District since from the beginning of the PBCR-Guwahati were revealed among different ethnic groups by this study. The results should help policy makers to formulate different strategies to control the level of burden as well as for treatment planning. This study also suggests that age is an important factor of cancer among different ethnic populations as well as for overall population of Kamrup District of Assam.
This survey is made to offer the fundamental data for the establishment of practical environmental education plan based on understanding of the change of the environmental awareness of elementary school students under the longitudinal-sectional research design. In this research, the questionnaire made by Kim Jong-ki in 1988 and by Kim Hak-Bong in 1993, is amended and filled up, which is used to the 624 numbers of fifth and sixth grade students lived in Seoul, Pyungtaek and Yangjugu. This research ares are devided into 5 ares which are the environmental general, environmental pollution, living environment, environmental education and consciouness of environmental crisis to humen beings. First, it is grasped general tendency and then is compared and analyzed the level of awareness by residence, sex, grade. stsdard of living parental academic, the background variation of parental job with the status in 1988 and 1933. The results are as follows: 1) The rate of interest for environmental pollution and population is reduced but the rate of interest for animal protection is increased. 2) In spite of reinforcement of environmental education In school, the numbers of the students who became to know some information about that from the class are diminished. 3) Even if the children are aware of sewage seriousely, the numbers of the students who answer it is caused by domestic sewage are a few. 4) On the environmental education area, the various materials of the are not utilized well in a class. 5) On the environmental crisis to the human beings the rate is much increased in 1993 ttan that of 1988 environmental contamination is the important cause of the human beings' crises but now the rate is reduced again. In other variables except the environmental contamination, it is increased the that of 1993 on the war, on population it is showed a tendency of reduction. The results of this study are as follows : 1) It is supposed that the education should be done only not for the knowledge of environmental education but for the practice of that - animal breeding, field experience of the ecological destruction places. 2) The various environmental education materials such as TV, VTR are demanded to give the students proper information about that and to educate sufficently. 3) The course of fields exploration for environmental education should be prepared under cooperation of the authorities concerned. 4) It has to be groped for an epoch-making teaching method and the training and the practice of teachers in order to reform environmental pollution.
A molecular marker is a molecule contained within a sample taken from an organism or other matter. The development of molecular techniques for genetic analysis has led to a great contribution to our knowledge of plant genetics and our understanding of the structure and behavior of various genomes in plants. Recently, functional molecular markers have been developed to detect the presence of major genes from the analysis of pedigreed data in absence of molecular information. DNA markers have developed into many systems based on different polymorphism-detecting techniques or methods such as RFLP, AFLP, RAPD, SSR, SNP, etc. A new class of very useful DNA markers called genic molecular markers utilizing the ever-increasing archives of gene sequence information being accumulated under the EST sequencing projects on a large number of plant species. Functional markers are derived from polymorphic sequences, and are more likely to be involved in phenotypic trait variation. Based on this conceptual framework, the marker systems discussed below are all (gene)-targeted markers, which have the potential to become functional. These markers being part of the cDNA/EST-sequences, are expected to represent the functional component of the genome i.e., gene(s), in contrast to all other random DNA based markers that are developed/generated from the anonymous genomic DNA sequences/domains irrespective of their genic content/information. Especially I sited Poczai et al’ reviews, advances in plant gene-targeted and functional markers. Their reviews may be some useful information to study molecular markers in plants.
Journal of the Korean Institute of Intelligent Systems
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v.13
no.3
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pp.322-327
/
2003
The water level of a steam generator of pressurized light water nuclear Power generator is known as a subject whose control is difficult because of a shrinking and swelling effect that is been mutually contradictory in a variation of feed water. In this paper, a neural network model selects first coordinative controller by a inappropriate gain of two PI controllers and the selected controller's gain is tuned by a fuzzy self-tuner. Model inputs consist of the water level, the feed water, and the stream flow. One controller of both coupling controllers whose gain is handled firstly is decided based upon above data. The proposed method can analyze patterns of signals using the characteristic of neural networks and select one controller that needs to be tuned through the observed result in this paper. If one controller between both the water level controller and the feed water controller is selected by the neural network model then a gain of the PI controller is suitably tuned by the fuzzy self-tuner. Rules of the fuzzy self-tuner drew from the pattern of input and output data. In the summary, the goal of this Paper is to select the suitable controller and tune the control gain of the selected controller suitably through such two processes.
Park, Mi-Yeon;Lee, Sangheon;Shen, Hongme;Leem, Choon Seong;Kim, Wooju
The Journal of Society for e-Business Studies
/
v.20
no.3
/
pp.29-46
/
2015
Examined how it varied the knowledge network of the country along with R&D changes in planning policy for the research and development of government. Therefore, in this study, chronological Analysis analyzed separately the network between each entity of participate in the industry fusion source technology development business of industry trade and Energy. Planning policy of industrial fusion source technology development business, to change the starting point before and after 2012, before 2012 from selected planning issues at the center "planning committee" and in 2012 'PD' changes to a system for planning issues around. First of all, an attempt to analyze the R&D network based on the "planning committee" current situation of 2009~2011, from 2012 to analyze the variation of the R&D network with the introduction of the 'PD' system after it was analyzed by dividing the time in the current state of up to 2013. The results of the analysis, since the PD system was introduced, such as self-relationship (the form of planning user to run directly challenges the person was planning to challenge participants)is greatly improved, I was able to grasp the effect became clear. The more the self-relation, and the budding scholars considering that there is inequality of the planning, the introduction of the PD scheme, it can be seen to have resulted in a positive effect. These studies, quantitatively analyzed to improve the results to the effects associated with changes in the planning policy of the government, I think that there is a meaning in terms of presenting the future direction of R&D policy.
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