• Title/Summary/Keyword: klebsiella pneumoniae

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An abattoir survey of incidence of pneumonia in slaughter pigs and an investigation of microbiology of affected lungs (도축돈의 폐렴병변 분포조사 및 폐렴병소로부터 호기성균의 분리동정)

  • 김경희;장영술;조민희;김수웅;김영은;김봉환
    • Korean Journal of Veterinary Service
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    • v.22 no.2
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    • pp.121-128
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    • 1999
  • The present study was conducted to investigate the incidence of pneumonic lesions with special regard to enzootic pneumonia and the microbiology of pneumoic lungs from 544 slaughter pigs during the period from October 1995 to September 1996. The incidence of enzootic pneumonic lesion was 76.3% (41s/s44) and pleurisy was detected from 7.9% of slaughter pigs. Seasonal prevalence of pneumonic lesions in slaughter pigs were in order of prevalence of 82.9% in spring, 76.8% in winter, 74.8% in autumn and 69.0% in summer, respectively. Pasteurella multocida, Streptococcus sp, Str suis, Corynebacterium sp, Actinobacillus pleuropneumoniae, Hemophilus parasuis, and Klebsiella pneumoniae were detected in order of prevalence from 16.9%, 15.9%, 7.5%, 6.0%, 1.4%, 1.0% and 0.5% of 415 pneumonic lungs, respectively. P multocida were susceptible to oxytetracycline, polymyxin-B, streptomycin, and vancomycin, while the majority of them were resistant to amoxicillin, ampicillin, cephalothin, kanamycin, and penicillin-G. Str suis were susceptible to amoxicillin, ampicillin, cephalothin, penicillin-G, although the majority of them were resistant to erythromycin, oxytetracycline, streptomycin, vancomycin. A pleuropneumoniae were susceptible to ampicillin, and cephalothin, but the majority of them were resistant to oxytetracycline.

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Weaving design of flame retardant jacquard fabrics for bedding (침장용 난연 자카드직물의 제직설계)

  • Ahn, Young-Moo
    • Journal of Fashion Business
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    • v.14 no.5
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    • pp.102-111
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    • 2010
  • The pegging board planning for jacquard weaves was carried out to express a big enough design in 60 inch width. 20 Kinds of fabrics were fabricated by a jacquard loom with a warp density of 168 yarns/inch, a weft density of 100T, and a weight of 180-220g/$m^2$ or 250-300g/$m^2$. The result of sanitary test about Escherichia coli, Staphilococcus aureus, Klebsiella pneumoniae and Salmonella typhimurium showed a sterilizing power of over 90% after cultivating for 30, 60, 120 minutes. And also its property was sustained after laundrying 20 times. The flame retardant properties showed a good result and complied with the flame retardant criteria of KOFEI 1001. Abrasion, laundry and light fastnesses of flame retardant fabrics showed 4-5 grades. The fabrics manufactured from 30's fiber appeared a little fluff and pill on the fabric. Therefore, they need a shearing process after finishing all processes to decrease the fluff or pill on the fabric. The flame retardant fabric manufactured from 30's and 40's fiber showed increased strength and elongation after soaping and dyeing finishing because the fabrics were shrunk.

Synthesis and Antibiotic activity of Dextran-Phthalysulfathiazole (Dextran-Phthalylsulfathiazole의 합성과 항균성)

  • 김판기;이기창;황성규;오세영
    • Journal of Food Hygiene and Safety
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    • v.12 no.3
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    • pp.228-233
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    • 1997
  • Drug Dclivcry system (DDS) purpose to getting better remedial result by improving medication from ordinary methods. Applied for DDS, to improve selectivity and comtinuity during absorbing and delivery step, polmer drug (prodrug) was prepared by the esterification with dextran in such of biodegradable polymer and phthalylsulfathiazole with is efficient for entilitis. The polymer durg was prepared with dextran and phthalylsulfathiazole by the esterification. The synthetic procedures of polymer drug was performed by acid chloride and DCC methods. Polymer drug was synthesized in high yield by acid chloride method than DCC method. The antibiotic activities of polymer drug exhibited growth-inhibitory activity against Staphylococcus aureus, Staphylococcus epidermidis, E. coli, Salmonella typhimurium, Klebsiella pneumoniae at the concentration of 500 *g/m* in general through in vitro. As a result of test, polymer drug has 1/2 MIC than phthalylsulfathiazole. Also, it has high level MIC as much as phthalylsulfathiazole with Proteus, Pseudomonas. We conducted possibility of DDS as an applied for medicine with synthesized polymer drug by using natrural polymer. We consider that clinical research must be followed to verify safety and efficacy for controlled release, activity and toxicity.

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The Functional Properties of Cellulose Fabric Treated with TiO2 - Focusing on Antibacterial activity, Deodorization & UV cut ability - (광촉매를 이용한 셀룰로오스섬유의 기능화에 관한 연구 - 항균·소취성 및 자외선 차폐성을 중심으로 -)

  • Kwon, Oh-Kyung;Moon, Jae-Gi;Son, Bu-Hun;Choi, Young-Hee
    • Fashion & Textile Research Journal
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    • v.5 no.4
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    • pp.395-398
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    • 2003
  • In this study, we measured the antibacterial activities, deodorization, UV cut ability, whiteness and SEM, according to the size($5{\mu}m$, $15{\mu}m$) of $TiO_2$, concentration(3%, 5%, 10%) and dipping temperature($50^{\circ}C$, $70^{\circ}C$) with using anatase type of $TiO_2$ photocatalyst. Photocatalyst is the substance which carries out functions, such as decomposition, removal, deodorization, antibacterial, etc. of a contaminant, in a place with light based on an oxidation-reduction reaction. The results of this study were as follow. Antibacterial activities are increased with increasing of the $TiO_2$'s concentration, and $TiO_2$ has high antibacterial activities for Staphylococcus aureus but it has low antibacterial activities for Klebsiella pneumoniae. The deodorization and UV cut ability is very good, therefore be able to get good effects with using only 3% of $TiO_2$. Every effects are increased by using small size of $TiO_2$ and high dipping temperature.

Pharmaceutical Studies on Inclusion Complex of Norfloxacin with ${\beta}-Cyclodextrin$ (Norfloxacin과 ${\beta}-Cyclodextrin$간의 Inclusion Complex에 관한 약제학적 연구)

  • Jee, Ung-Kil;Park, Mork-Soon;Kwon, Joong-Moo
    • Journal of Pharmaceutical Investigation
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    • v.17 no.1
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    • pp.1-14
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    • 1987
  • To increase the bioavailability of norfloxacin, inclusion complex of antimicrobial agent norfloxacin with ${\beta}-Cyclodextrin$ was prepared and studied by the solubility method, spectrophotometric methods(UV, IR, $^1H-NMR$), differential thermal analysis, powder X-ray diffractometry, the physical properties, the antimicrobial activity, DNA binding and in situ recirculation technique. The conclusions are summerized as following; 1) The inclusion complexation was identified by means of solubility, spectrophotometry(UV, IR, NMR), DTA and X-ray diffraction. 2) The molar ratio of $norfloxacin-{\beta}-cyclodextrin$ complex was 1 : 1. 3) The stability constant of $norfloxacin-{\beta}-cyclodextrin$ complex was $21.5\;M^{-1}$, and both true and apparent partition coefficients of the inclusion complex were larger than those of norfloxacin. 4) The time required to dissolve 60% $(T_{60}%)$ of the inclusion complex was 120 min. in distilled water and in the artificial intestinal juice, while norfloxacin did not reach to 60% dissolution within 120 min. 5) The antimicrobial activity of the inclusion complex against Pseudomonas aeruginosa, Klebsiella pneumoniae and Staphylococcus aureus showed no significant difference compared to that of norfloxacin alone. 6) Studies on binding properties between the inclusion complex and norfloxacin alone to DNA according to equilibrium dialysis showed no significant differency. 7) In situ absorption rates (Ka) of inclusion complex and norfloxacin alone were 0.229 and $0.102hr^{-1}$, respectively.

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The Dyeing Properties and Antibacterial Activity of Fabrics Dyed with Camomile Extract (캐모마일 추출액 염색직물의 염색성 및 항균성)

  • Park Young-Hee
    • Journal of the Korean Society of Clothing and Textiles
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    • v.29 no.8 s.145
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    • pp.1188-1195
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    • 2005
  • The effects on the dyeing properties and antibacterial activity of fabrics dyed with camomile extract were analyzed. As the results obtained, the surface color of all the dyed fabric was tinged with the yellow of the bright color tone. In the test results of durability, the durability to sunlight of the dyed fabric of both cotton and silk showed from 2nd grade to 3rd grade. The durability to laundry of the dyed fabric of both cotton and silk showed relatively higher grade of 4th-5th. The durability to synthetic sweat of all the fabrics except fer the dyed fabric mordanted with $CuSO_4{\cdot}5H_2O$ showed the relatively good result of 3rd- 5th grade. The durability to friction and dry cleaning of all the dyed fabrics showed the excellent result of 4th-5th grade. In the test results of antibiosis, the dyed fabric of cotton showed the decrease rate of $50\%$ to Staphylococcus aureus and the decrease rate of $70\%$ to Klebsiella pneumoniae. The dyed fabric of silk showed the significant effect with Microscopic growth to the mold bacillus Aspergillus niger.

On the chinoform metal chelate (Chinoform metal chelate에 관한 연구)

  • 지달현
    • YAKHAK HOEJI
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    • v.17 no.4
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    • pp.235-243
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    • 1973
  • Determinations of the compositioin ofl chinoform metal chelates by elemental analysis and molar ratio method showed that the ratios of the ligand to metals in chinoform Cu(II) chelate, chinofrm Ni (II) chelate, and chinoform CO(II) chelate were 2:1 respectively and that the ratio in chinoform Fe(III) chelate was 3:1. It was found that diffe rential thermal values vary with the center metalic ions and that the thermal stability was in anorder of Fe>Cu>Co>Ni. The indices of over-all stability constant of chinoform Cu(II) chelate, Ni(II) chelate, Co(II) chelate, and Fe(III) chelate were 15.57, 15.16, 15.40 and 20.76, respectively, and the over-all stability was in an order of Fe>Cu>Co>Ni. The tests of the natibacterial activity in vitro of the chinoform metal chelates against Staphylococcus aureus ATCC G538, Pseudomonas aeruginosa 2131, Serratia marcescens 3357, Klebsiella pneumoniae 8899, Enterococcus 3309, Streptococcus pyogenes 507, and Escherichia coli 125 showed that the Cu(II) chelate generally had greater activity than chinoform, that it had four-fold activity particularly against Streptococcus pyogenes 507 and Staphylococcus awreus ATCC 6538, that the Ni(II) and Co(II) chelates had almost same activity, and that the Fe chelate had strong activity against Escherichia coli 125.

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Antifungal Activities of Copper(II) with Biosensitive Macrocyclic Schiff Base Ligands Derived from 4-Aminoantipyrine Derivatives

  • Gopalakrishnan, S.;Joseph, J.
    • Mycobiology
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    • v.37 no.2
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    • pp.141-146
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    • 2009
  • Novel copper(II) complexes have been synthesized from the macrocyclic Schiff bases derived from Knoevenagel condensed ${\beta}$-ketoanilides (obtained by the condensation of acetoacetanilide and substituted benzaldehydes), 4-aminoantipyrine and ophenylene diamine. The structural features have been determined from their analytical and spectral data. All the Cu(II) complexes exhibit square planar geometry. Their high molar conductance values support their 1 : 2 electrolytic nature. The magnetic moment data provide evidence for the monomeric nature of the complexes. The X-band ESR spectra of the |$CuL^1$|$(OAc)_2$ in DMSO solution at 300 and 77 K were recorded and their salient features are reported. The in vitro biological screening effects of the investigated compounds were tested against the bacterial species Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Proteus vulgaris and Pseudomonas aeruginosa and fungal species Aspergillus niger, Rhizopus stolonifer, Aspergillus flavus, Rhizoctonia bataicola and Candida albicans by well diffusion method. A comparative study of inhibition values of the Schiff bases and their complexes indicate that complexes exhibit higher antimicrobial activity than the Schiff bases. Copper ions proved to be essential for the growth-inhibitor effect. The extent of inhibition appeared to be strongly dependent on the initial cell density and on the growth medium.

Staged lower lip reconstruction following gangrenous stomatitis in an immunosuppressed patient

  • Jin, Han Byeol;Yang, Jeong Yeol;Kim, Kyung Sik;Kim, Seung Hong;Choe, Joon;Chung, Jee Hyeok
    • Archives of Craniofacial Surgery
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    • v.19 no.3
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    • pp.222-226
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    • 2018
  • A 70-year-old male with a history of diabetes mellitus, hypertension, and coronary stent insertion visited our hospital 7 days after biting his lower lip. Swelling and inflammation had worsened despite debridement and antibiotic treatment. On the 8th hospital day, fungal infection with Candida albicans and superimposed bacterial infection with Klebsiella pneumoniae were found on tissue culture. Extensive necrosis resulted in a defect of approximately 3/4 of the entire lower lip and a full-layer skin defect from the vermilion to the gingivobuccal sulcus at the right corner of the mouth. To correct drooling, incomplete lip sealing, and trismus, staged reconstruction was performed with consideration of cosmetic and functional features. The treatment process using staged reconstruction and antifungal treatment for an extensive lower lip defect caused by fungal stomatitis is described.

Antimicrobial Potential of Moringa oleifera Seed Coat and Its Bioactive Phytoconstituents

  • Arora, Daljit Singh;Onsare, Jemimah Gesare
    • Microbiology and Biotechnology Letters
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    • v.42 no.2
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    • pp.152-161
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    • 2014
  • The in vitro antimicrobial potential of the unexplored Moringa oleifera seed coat (SC) was evaluated against some Gram-positive and Gram-negative bacteria and yeast pathogens. Antimicrobial studies with various solvent extracts indicated ethyl acetate to be the best extractant, which was used for the rest of the antimicrobial studies as it tested neither toxic nor mutagenic. Gram-positive bacteria including a methicillin resistant Staphylococcus aureus (MRSA) strain were more susceptible with a minimum inhibitory concentration (MIC) range of 0.03-0.04 mg/ml. The antimicrobial pharmacodynamics of the extract exhibited both concentration-dependent and time-dependent killing. Most of the test organisms exhibited a short post antibiotic effect (PAE) except Enterococcus faecalis, Staphylococcus aureus, and Klebsiella pneumoniae 1, which exhibited longer PAEs. Amongst the major phytoconstituents established, flavonoids, diterpenes, triterpenes and cardiac glycosides exhibited inhibitory properties against most of the test organisms. The identified active phytochemicals of the M. oleifera seed coat exhibited antimicrobial potential against a wide range of medically important pathogens including the multidrug-resistant bugs. Hence, the M. oleifera seed coat, which is usually regarded as an agri-residue, could be a source of potential candidates for the development of drugs or drug leads of broad spectrum that includes multidrug-resistant bugs, which are one of the greatest concerns of the $21^{st}$ century.