• Title/Summary/Keyword: kindney

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EROGOTHIONEINE RESCUES PCl2 CELLS FROM BETA-AMYLOID-INDUCED APOPTOTIC DEATH

  • Jang, Jung-Hee;Surh, Young-Joon
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.141.2-142
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    • 2003
  • beta-Amyloid (A$\beta$) peptide is the major component of senile plaques and considered to have a causal role in the development and progression of Alzheimer's disease. There has been compelling evidence supporting that $A\beta$-induced cytotoxicity is mediated through oxidative and/or nitrosative stress. Recently, considerable attention has been focused on dietary manipulation of oxidative and/or nitrosative damage. L-Egrothioneine (EGT) is a low-molecular weight naturally occurring thiol compound of dietary origin which exists in milimolar concentrations in the brain, liver, kindney, erythrocytes, ocular tissues and in seminal fluids of mammals. (omitted)

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Physical and Electrical Properties of Carbon Black/PVDF Composite Electrode as Ohmic Joule Heater (면상발열체용 Carbon Black/PVDF 복합전극의 물리 및 전기적 특성)

  • Doh, Chil-hoon;Jin, Bong-soo;Moon, Seong-in;Chung, Young-Dong;Jeong, Dong-yong;Bang, Young-dal
    • Applied Chemistry for Engineering
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    • v.20 no.6
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    • pp.692-695
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    • 2009
  • Ohmic joule heating electrodes were developed for the electrical heater of the floor of a room. A composite slurry of super pure black and polyvinylidene fluoride with/without the additives of multi-walled carbon nanotube or kindney stone powder was coated as a thin film on the polyethylene terephthalate film. The performances of heating electrodes were evaluated checking specific conductivity, adhesion strength and hardness. The addition of kindney stone powder increases specific resistance and hardness in a small extent. However, the addition of carbon nanotube increases specific conductivity and hardness. The properties of various compositions of ohmic joule heating electrodes were evaluated.

Studies on Diuretic Action of Bumetanide (Bumetanide의 이뇨작용에 관한 연구)

  • 고석태;김일용
    • YAKHAK HOEJI
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    • v.29 no.3
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    • pp.130-143
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    • 1985
  • Bumetanide, when given intravenously in dogs, induced a potent diuresis with an increased amounts of sodium and potassium excreted in urine due to inhibition of reabsorbing them in renal tubule. Furthermore, clearances of osmolar substance and para-aminohippuric acid were increased, but clearace of free water diminished without any change of creatinine clearance. Bumetanide, administered directly into a renal artery, elicited diuresis only in the infused(experimental) kidney by the same mode of action as in the intravenous cases in renal function of the dog. Renal effects of intravenous bumetanide after pretreatment with the small dose of indomethacin (5.0mg/kg) revealed reduction only in clearance of paraaminohippuric acid. However the much dose of indomethacin (5.0mg/kg+5.0mg/kg/hr) or arachidonic acid showed a significant inhibition in the change rates of all renal function by bumetanide. Morover, pretreatment of probenecid also made a marked reduction in renal effects induced by bumetanide. From the above results, it is thought that bumetanide causes diuretic action due to dual mechanism inhibiting reabsorption of electrolytes in loop of Henle and increasing blood flow in kindney, that are provoked through the mediation of prostaglandins.

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Effect of Ovariectomy Induced Hyperphagia on the Intestinal Adaptation (난소절제에 의해 유발된 과식현상이 소장적응변화에 미치는 영향)

  • 윤정한
    • Journal of Nutrition and Health
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    • v.21 no.3
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    • pp.182-187
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    • 1988
  • Ovariectomy induced hyperphagia was reported in various animal models. It was postulated that hyperphagia resulted in interstinal hypertrophy and hyperplasia. Therefore, this study was performed to compare the food intake and intestinal changes between ovariectomized rats(OVX) and sham operated rats(Sham). Results of this study showed that the food intake and body weight of OVX animal was significantly higher than those of Sham animal. This results confirmed the effect of ovarian hormone on the food intake regulation. Hyperphagia induced by ovariectomy influence the intestinal cell growth and showed hyperplasia determined by protein/DNA ratio. Maltase and alkaline phosphatase activity suggested that the intestinal cell was fully matured in body groups. There were no difference in weight of other organs, such as liver, heart and kindney between two groups.

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Simultaneous Determination of Residual Sulfonamides in Meat Tissues by High Performance Liquid Chromatography (HPLC에 의한 식육조직중의 잔류 설파제 동시 분석)

  • 강희곤
    • Journal of Food Hygiene and Safety
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    • v.9 no.1
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    • pp.37-42
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    • 1994
  • Four sulfoanmides ; sulfamerazine ; sulfamethazine, sulfathiazole and sulfadimethoxine from muscle, kindney, liver and heart tissues of pork and chicken by LC. Residual sulfonamides were extracted with dichloromethane and determined on a Sperisorb ODS-1 column(250mm$\times$4.6mm id) with acetonitrile/water/acetic acid (30/70/0.3 v/v) as a mobile phase at 260nm. Recoveries from 4 tissues of pork and chicken samples fortified with 50 and 100 ppb were 71.2~87.2% and 73.7~89.6%, respectively. The detection limit was 0.03 $\mu\textrm{g}$/g in each drug. Sulfamethazine in 5 samples of pork. And sulfadimethoxine in 5 samples and sulfamethazine in 3 samples were also detected from 41 samples of chicken. The order of residue levels of sulfonamides in tissues was kidney>liver>heart>muscle, respectively. The residue levels of sulfonamides from kidney and liver were 0.03~0.15 $\mu\textrm{g}$/g in porks and 0.03~0.10 $\mu\textrm{g}$/g in chickens.

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Study on the Accumulative Distribution of Malation and itns Determination form the Human Tissue. (사체중 MaIathion의 각 장기조직별 분석 및 정량에 관한 연구)

  • 이완구;박성우
    • Journal of Environmental Health Sciences
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    • v.5 no.1
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    • pp.18-20
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    • 1978
  • An experimental study was conducted to determine the quantity of contamination of organophosphrous pesticides accumulated in each human tissues. The samples used for this experiment were spleen, lung, heart, liver and kindney and those tissues were homogenized by a blender. The homogenized materials was extracted with mixed solvent, acetone/benzene (1:1) and cleaned up on a activated carbon column and determined by gas chromatography using AFID supported on 5% QF-1. The average recovery rate was 94% and the results obtained are summarized as follows. 1) The quantities of Malathin accumulated in each tissues were 0.53 ppm in spleen, 0.42 ppm in lung, 0.34 ppm in kidney, 0.19 ppm in heart and 0.19 ppm in liver. 2) Residues of pesticides in chronic or acute intoxicated tissues were highest in the spleen, decreasing in order of the lung, kidney, heart, and liver. 3) According to the above resuk we can conclude that the most proper material in detecting the pesticide is the spleen.

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The effect of ethanol on zinc, calcium and copper concentrations of tissues in rats (Rat에 있어서 ethanol투여가 체조직의 무기질 함량에 미치는 영향)

  • Lee, Keun-woo;Lee, Hyun-beom
    • Korean Journal of Veterinary Research
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    • v.29 no.1
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    • pp.7-11
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    • 1989
  • This study was designed in order to clarify the effect of ethanol drinking on the mineral contents on liver, kidney, muscle and hair. Forty-five rats were divided into 2 groups and a control group. The control group received tap water and the other 2 groups were given 8% and 40% ethanol as drinking source. Liver, kindney, muscle and hair samples were taken and analyzed for zinc, calcium and copper contents by atomic absorption spectrophotometric methods. The results obtained are summrized as follows; 1. The zinc content of muscle showed significant (p<0.01) decrease in both groups. 2. The calcium content of hair showed significant (p<0.1) increase in 8% ethanol group. 3. The copper contents of kidney and muscle in 8% ethanol group and liver in 40% ethanol group showed significant (p<0.1) decrease.

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Studies on Myxosporidian parasites From Korean Freshwater fishes 1.Myxosporidian parasites from Dongjin River, Jeonbuk province of Korea (한국산 담수어에 기생하는 포자충류에 관한 연구 1. 동진강 담수어의 포자충)

  • Kim, Young-Gill;Kim, Dae-Young
    • Journal of fish pathology
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    • v.18 no.1
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    • pp.1-18
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    • 2005
  • This study was performed to investigate the myxosporidian parasites from several organs of freshwater fishes caught from Dongjin River, Jeonbuk Province of Korea. Twelve myxosporidian species were dectected from five fish species out of sixteen fish species. From the gall bladder of Opsariichthys uncirostris amurensis, Zschokkella opiocephali was found; from the skin, gall bladder, liver and spleen of Pseudobagrus fulvidraco, Zschokkella opiocephali and Myxobolus cheisini were found; from the gill, skin, gall bladder and kidney of Carassius carassius, Zschokkella ctenopharyngodonis, Chloromyxum koi, Sphaerospora sinensis, Myxosoma abbottinae, Myxobolus koi and Myxobolus suturalis were found; from the kindney of Misgumus anguillicaudatus, Myxidium lieberkuhni, Neomyxobolus ophicephali and Telohanellus misgurni were found; from the gill of Cyprinus carpio, Myxosoma abbottinae and Myxobolus dispar were found. All these parasitized fishes didn't show any specific symptom.

PRIMARY INTRAOSSEOUS CARCINOMA;REPORT OF 2 CASES (악골에서 발생한 원발성 상피암;2례 보고)

  • Park, So-Yeon;Kim, Jin;Lee, Choong-Kook;Park, Hyung-Rae;Kim, Il-Kyu
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.12 no.2
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    • pp.62-68
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    • 1990
  • Intraosseous carcinoma of the jaw may arise as metastatic lesions most commonly from breast, lung, kindney and thyroid and also primarily occur from ameloblastoma or odontogenic cyst. Rarely primary intraosseous carcinoma could be originated from the epithelium involved in odontogenesis. According to WHO's classification, primary intraosseous carcinoma is defined as squamous cell carcinoma, occured in the Jaw without connection to the oral mucosa. However, Elzay defined primary intraosseous carcinoma as malignant epithelial tumor related to the odontogenic apparatus, including carcinoma ex-odontogenic cyst, carcinoma ex-ameloblastoma and carcinoma de novo. We experienced 2 cases of intraosseous carcinoma of the jaw. The first case, a 59-year-old man, showed a ill-defined mass on the left maxilla, measuring $8{\times}10cm$ in size. He received radical hemimaxillectomy and was diagnosed as ameloblastic carcinoma. The second case obtained from a 79-year-old woman showed a ill-defined $6{\times}8cm$ sized mass on the left mandibular body area. The mass was surgically removed by partial mandibulaectomy, which was diagnosed as the primary intraosseous carcinoma, probably odontogenic origin.

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Histopathology of a rhabdoviral disease of farmed flounder Paralichthys olivaceus (양식 넙치(Paralichthys olivaceus)에서 발생한 랩도바이러스성 질병의 병리조직학적 특징)

  • Lee, Nam-Sil;Kang, Hyung-Gil;Choi, Hee-Jung;Chun, Se-Kyu;Park, Nam-Kyu;Huh, Min-Do
    • Journal of fish pathology
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    • v.15 no.1
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    • pp.1-7
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    • 2002
  • On April of 2000 and February of 2001, a disease characterized by darkening, ascites and enlargement of the spleen occurred in flounder, Paralichthys olivaceus, farmed near northern and eastern coasts of Korea. Various degree of necrosis including liquefactive-type was observed mainly in hemopoietic tissue of spleen and kindney. Certain tissue such as branchial soft tissue including epithelium showed a similar necrotic findings. But some tissues such as intentine had several necrotic clusters of wandering cells, being possibly leukocytes. Necrotic evidences of blood cells were evident in various tissues including hemopoietic tissues. Necrobiotic bodies were frequently encountered in blood smear preparations. Bullet type-virious were detected in the spleenic cells. Each virion was about 500 nm in diameter and 170nm in length. From these results, this disease was thought to be a rhabdoviral disease.