• Molecules and Cells
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• v.41 no.1
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• pp.45-49
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• 2018

Autophagy is a lysosome-dependent degradation process that is essential for maintaining cellular homeostasis. In recent years, more studies have focused on the late stages of autophagy. Our group discovered and studied the terminal step of autophagy, namely autophagic lysosome reformation (ALR). ALR is the process that regenerates functional lysosomes from autolysosomes, thus maintaining lysosome homeostasis. ALR involves clathrin-mediated membrane budding from autolysosomes, elongation of membrane tubules along microtubules with the pulling force provided by the motor protein KIF5B, proto-lysosome scission by dynamin 2, and finally maturation of proto-lysosomes to functional lysosomes. In this review, we will summarize progress in unveiling the molecular mechanisms underlying ALR and its potential pathophysiological roles.

• Journal of Advanced Marine Engineering and Technology
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• v.28 no.4
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• pp.577-586
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• 2004

Structural failures, such as crack initiation, often arise near the bolted parts of the side member and trunnion bracket in some commercial vehicles. The purpose of this paper is: 1) establishment of a simple and practical bolted joint modelling technique and 2) determination of the key design variables for design improvement based on numerical experiments. Once the bolted joint modelling technique is established through experimental verification, the key design variables must be identified in order to alleviate the level of the stress concentration near the problem region. Numerical results indicate that the torsional rigidity of the frame cross-section should be increased to reduce the level of the maximum stress at the actual crack initiation location.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2019.11a
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• pp.224-225
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• 2019

The purpose of this study was to develop a technology to prevent leakage of construction structures for the Chinese market. The first key development factor is to establish a joint quality standard that corresponds to all performance criteria set out in Chinese Standard JC / T 2428-2017. The second key development factor is to develop a product capable of exhibiting performance in a low temperature environment of $-30^{\circ}C$ and coping with 15mm structure behavior.

• International Area Studies Review
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• v.22 no.1
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• pp.79-99
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• 2018

According to the literature, the studies on the effects of the characteristics of the international joint venture partners on joint venture performance are mainly focused on partial aspects of partners characteristics, and the studies that investigate a mediating effect of alliance commitment on the relationship between partners characteristics and joint venture performance are scarce. Hence, this research intends to identify comprehensive partners characteristics, including CEO leadership behaviors similarity, strategic similarity, resources similarity, and organizational similarity and examines their effects on alliance commitment and joint venture performance. The results reveal that CEO leadership behaviors similarity and organizational similarity have a positive influence on alliance commitment and joint venture performance, whereas strategic similarity and resources similarity have a negative influence on alliance commitment and joint venture performance. It is also found that alliance commitment affects joint venture performance positively and mediates the relationship between partners characteristics and joint venture performance. Based on these results, key conclusions and implications are discussed.

• Asian Journal of Innovation and Policy
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• v.4 no.2
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• pp.178-199
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• 2015

This study provides a background on the growth of Indian automobile industry under different regulatory regimes. It is observed that the international joint ventures have played a key role in the growth of the sector. The study further examines the motives for forming IJVs in the auto component sector and also identifies the criteria for choosing the joint venture partner to mitigate conflicts. These two specific attributes form the core towards transfer of technology, promoting innovation and also act as a catalyst for adopting and choosing appropriate technology. The study brings out the relationship between motives, partner selection criteria and performance of the IJVs. Results indicate that firms gave maximum importance to technological skills, quality control measures and proprietary knowledge in selecting IJV partners. It is also observed that the motives affect the partner selection criteria in terms of skill and resources needed from the partner.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.23 no.12
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• pp.1090-1095
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• 2013

This paper describes the FEM analysis for squeak problem of the ceramic-on-ceramic hip joint system. The onset of hip squeak is estimated by the positive real parts of the eigenvalues in the hip joint system. From the complex eigenvalue analysis, the unstable frequencies and the corresponding mode shapes are determined at the certain severe friction coefficients. It is found that some bending and torsion modes of the femoral stem can be unstable due to the mode-coupling mechanism. It also shows that the magnitude of the friction coefficient plays a key role on the occurrence of hip squeak.

• Proceedings of the KSME Conference
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• 2008.11a
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• pp.1570-1574
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• 2008

Various mechanical test were conducted on conventional and crosslinked ultra-high molecular weight polyethylene(UHMWPE) all prepared from the same lot of medical grade GUR 1050 for artificial joint. The conventional materials were not irradiated and treated by heating. The cosslinked materials were irradiated with $25kGy{\sim}200kGy$ by gamma-ray andthen annealed or remelted. Gamma-ray irradiation and heat treatment process were found to significantly impact the crystallinity, and hence the mechanical behavior, of the highly crosslinked UHMWPE. The radiation dose and heating conditions were key predictors of the uniaxial yielding, plastic flow, and failure properties of conventional and highly crosslinked UHMWPE. The correlation model from experiments would be the basic information to enhance the were resistance of artificial joint liner.

• 한국신재생에너지학회:학술대회논문집
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• 2009.11a
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• pp.135-138
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• 2009

Quality evaluation of laser welded MCFC separator panels with large active area was performed. Lap joint was applied to produce stable air-tight seam weld by employing Nd:YAG laser. Results showed that surface contamination played a key role to form weld defects at the joint interface. However, there was no evidence that weld width at the lap joint changed after the stack operation time of 2,890h. Test results also revealed that the reinforcement values which were measured on the weld line after long time operation, were stable.

• International conference on construction engineering and project management
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• 2007.03a
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• pp.749-758
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• 2007

Learning has become an important aspect for any organization to stay relevant and competitive in the corporate world of survival. In construction industry, the international construction joint ventures (ICJVs) provide an excellent platform with opportunity of learning among partners seeking to develop new area of competency and improve their overall competitiveness for their next project endeavor. This paper discusses the development of a conceptual model of effective learning in ICJVs using four major stages of development in a typical joint venture (JV) 's process. The study identified that there are three key constructs that contribute to effective learning comprising learning conditions in the JV's pre-inception stage, success factors of JV for learning in the forming & organizing stage, and learning actions in the implementation & adjustment stage. The effective learning outcomes are measured by the characteristics of learning organization during the JV's completion & evaluation stage. Details and issues of each stage and the methodology of research will be presented and discussed.

• International journal of advanced smart convergence
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• v.12 no.3
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• pp.61-67
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• 2023

Gait analysis plays a key role in the research field of exploring and understanding human movement. By quantitatively analyzing the complexity of human movement and the various factors that influence it, it is possible to identify individual gait characteristics and abnormalities. This is especially true for people with walking difficulties or special circumstances, such as amputee, for example. This is because it can help us understand their gait characteristics and provide individualized rehabilitation plans. In this paper, we compare and analyze the differences in ankle joint motion and angles between normal and amputee. In particular, a filtering process was applied to the ankle joint angle data to obtain high accuracy results. The results of this study can contribute to a more accurate understanding and improvement of the gait patterns of normal and amputee.