• Journal of Microbiology and Biotechnology
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• 제18권3호
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• pp.503-511
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• 2008

An edible marine red alga, Grateloupia filicina, collected from Jeju Island of Korea was hydrolyzed by cheap food-grade carbohydrases (Viscozyme, Celuclast, AMC, Termamyl, and Ultraflo) to investigate its anticoagulant activity. Among the tested enzymatic extracts of G. filicina, a Termamyl extract showed the highest anticoagulant activity. Anion-exchange chromatography on DEAE-cellulose and gel-permeation chromatography on Sepharose-4B were used to purify the active polysaccharide from the crude polysaccharide fraction of G. filicina. The purified sulfated polysaccharide (0.42 sulfate/total sugar) showed ${\sim}1,357kDa$ molecular mass and was comprised mainly of galactose(98%) and 1-2% of glucose. The sample showed potential anticoagulant activity on activated partial thromboplastin time (APTT) thrombin time (TT) assays. The purified G. filicina anticoagulant (GFA) inhibited the coagulation factor X (92%), factor II (82%), and factor VII (68%) of the coagulation cascade, and the molecular interaction (protein-polysaccharide) was highly enhanced in the presence of ATIII (antithrombin III). The dissociation constant of polysaccharide towards serine proteins decreased in the order of FXa (58.9 nM) >FIIa (74.6 nM) >FVII (109.3 nM). The low/less cytotoxicity of the polysaccharide benefits its use in the pharmaceutical industry; however, further studies that would help us to elucidate the mechanism of its activity are needed.

• 대한치과기공학회지
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• 제37권4호
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• pp.243-250
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• 2015

Purpose: The aim of this study was to investigate the shear bond strength between various commercial zirconia coping and veneering ceramic, and to observe the failure mode. Methods: For each zirconia block (iJAM Emerald, LUXEN Smile block, ICE Zirkon transluzent), 10 rectangular specimens were layered with Cercon ceram kiss, IPS e.max ceram, ICE Zirkon ceramic according to recommended by the manufacturer. The shear bond strength tests of the veneering porcelain to zirconia were carried out until fracture by a universal testing machine. After the shear bond tests, failure modes were characterized visually, under a stereomicroscope, such as adhesive, cohesive, or mixed. Data were analyzed with One-way ANOVA followed by Scheffe's tests. Results: The shear bond strength ($mean{\pm}SD$) of zirconia-veneer ceramic were JC group $13.9{\pm}3.6MPa$; JE group $17.7{\pm}2.4MPa$; JI group $15.1{\pm}2.5MPa$; LC group $9.5{\pm}1.5MPa$; LE group $16.2{\pm}2.3MPa$; LI group $12.6{\pm}0.8MPa$; ZC group $16.0{\pm}2.3MPa$; ZE group $18.5{\pm}3.4MPa$; and ZI group $15.3{\pm}3.2MPa$. The One-way ANOVA showed a significant difference between groups (p<0.05). The failure mode in most experimental groups was mixed failure, except for the LC group, which showed adhesive failure, and JE group, LE group and ZE group showed cohesive failure. Conclusion: For IPS e.max ceram, the shear bond strength value was highest for all kinds of zirconia blocks. For ICE Zirkon transluzent, the shear bond strength value was highest for all kinds of veneering ceramics. Most of experimental group interfaces revealed mixed failure mode.

• 한국축산식품학회지
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• 제35권4호
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• pp.507-514
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• 2015

Deer velvet antler (DVA) is one of the most popular medicines in China. Numerous studies have demonstrated that velvet antler possess biological effects. However, data regarding its anti-migration activity on prostate cancer is scarce. In this study, we investigated the inhibitory effect of top DVA (T-DVA) on the expression of prostate-specific antigen (PSA) and migration-related genes in the human prostate cancer cell, LNCaP. The T-DVA down-regulated the expression of PSA. In addition, the Radius^TM assay revealed that T-DVA inhibited the migration behavior of prostate cancer cells. Furthermore, the expression of matrix metalloproteinase (MMP)-9 and vascular endothelial growth factor (VEGF) was also decreased with T-DVA. On the contrary, T-DVA increased the tissue inhibition of metallo-proteinase (TIMP)-1 and (TIMP)-2. Taken together, our findings indicate that the T-DVA possesses anti-migration activity on prostate cancer cells. This is the first study of DVA to report the anti-migration activity on prostate cancer.

• 한국항해항만학회:학술대회논문집
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• 한국항해항만학회 2010년도 춘계학술대회
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• pp.448-452
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• 2010

전통적인 항로표지는 등광(등명기)에 의존하여 항로 및 위험물을 표시함으로써 통항선박의 안전을 확보하여 왔으나, 울산항을 비롯한 전국 무역항에서 입지조건이 유리한 항만배후단지가 개발됨에 따라 항만배후광이 증가하였고 항로표지의 야간시인성이 현격하게 떨어지는 현상이 발생하였다. 또한, 전국 무역항에서는 채선율 저감을 통한 항만 운영율 향상을 위하여 야간 입출항 제한규모를 단계적으로 상향하고 있어 이에 대비한 통항선박의 안전확보방안 마련이 시급히 요구되고 있는 실정이다. 이에 항행원조시설인 등대 및 등표 등에 등탑직적조명방식(LED논네온 등)을 비롯한 고광력 등명기 등이 적용되었고, 상대적으로 시인성이 떨어지는 등부표에는 시인성 향상과 선위결정이 용이하도록 LED발광번호판을 개발하여 적용한 결과, 항만 이용자들로부터 호평을 받고 있으며 앞으로도 항만배후광 극복을 위한 항로표지의 발전은 계속되어야 할 것이다.

• 한국축산식품학회지
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• 제30권1호
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• pp.20-27
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• 2010

Deer velvet antler was subjected to the extraction process using boiling water at three different temperatures (100, 110 and $120^{\circ}C$) and 70% ethanol solution. Functional components such as uronic acid, sulfated-glycosaminoglycans (sulfated-GAGs) and sialic acid in the extracts were analyzed, and their antioxidant activities were investigated using several in vitro models. Uronic acid and sulfated-GAGs content of each extract significantly decreased with increasing extraction temperature (p<0.05), while the residues obtained from the upper and middle part of the antler had a higher uronic acid content than the residues obtained from the base section. Sialic acid contents were highest in compounds extracted at $110^{\circ}C$, followed by 120 and $100^{\circ}C$. The 70% ethanol extracts also had a high levels of uronic acid content, but not for sulfated-GAGs and sialic acid. All extracts showed good antioxidant ability in a dose-dependant manner, with the $100^{\circ}C$ residue exhibiting the strongest activity compared to the 110 and $120^{\circ}C$ extracts. In relation to the hydroxyl radical scavenging activity and reduction power, the 70% ethanol extract exhibited the strongest activity. Furthermore, the velvet antler extracts inhibited apoptosis in hydrogen peroxide-induced PC-12 cells.

• 전자공학회논문지SC
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• 제43권5호
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• pp.19-27
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• 2006

본 논문은 사족 보행 로봇에 대한 내고장성 걸음새의 안정여유도를 개선하는 방법을 논한다. 기존에 제안되었던 재고장성 걸음새는 사족 보행 로봇이 다리 고장이 발생한 후에도 보행을 계속할 수 있게 하였다. 하지만 내고장성 걸음새가 임계 안정여유도를 가지므로 몸체 무게중심의 위치가 순차적으로 바뀔 때에는 걸음새가 불안정해질 수 있다는 약점을 지니고 있다. 본 논문에서는 이러한 약점을 극복하기 위해서 양(陽)으로 안정여유도를 가지는 내고장성 걸음새를 관절고착고장에 대해서 제안한다. 관절고착고장은 로봇 다리의 관절 하나가 한 지점에 고착되어 더 이상 움직일 수 없는 상태를 말한다. 양의 안정여유도는 걸음새 동작 과정에서 한 다리가 이동하기 전에 지지 다리들의 위치를 조정함으로써 얻어질 수 있다. 제안된 걸음새의 우수성을 입증하기 위해서 안정여유도, 보폭 등의 매개 변수들을 중심으로 기존 걸음새와 성능 비교를 수행한다.

• 한국건축시공학회지
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• 제7권1호
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• pp.115-121
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• 2007

Ordinary concrete uses aggregate sufficiently soaked with water, and is weighed, mixed with other materials and placed in accord with performances required in the construction field. Recently special concrete with high fluidity and durability is required but it is difficult to use top-quality concrete due to lack of high-quality aggregate, delayed transportation because of traffic jam, etc. In addition, sometimes the use of a remicon is inevitable just for small-sized concrete constructions or it is difficult for a remicon to reach remote construction places such as mountainous areas. To solve these problems, this study attempted to pack concrete materials. In other words, it is to instantize concrete. This study dried aggregate, a material of concrete, and compared the change of absorption phase of the aggregate in water and in paste in order to examine the effect of the dryness of aggregate on its absorption rate and, based on the absorption rate, decided water addition ratio necessary for the reduction of unit quantity caused by the use of dry aggregate in designing concrete mixture, and analyzed the properties of unhardened concrete according to water addition ratio in manufacturing concrete using aggregate in the state of absolute dryness and in the state of surface dryness.

• 복식
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• 제57권5호
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• pp.140-150
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• 2007

The study aimed to classify the synonyms of clothing terms, such as equal relationship, connoting relationship and partial relationship. The subjects of the study are eleven Chinese character study books such as <石峰千字文 Seokbongcheonjamun> <丙子本千字文 Byeongjacheonjamun>, <註解千字文 Juhaecheonjamun>, <訓蒙字會 Hungmongjahoi>, <新增類合 Sinjeungyuhap>, <兒學編 Aahakpyeon(1816) (1908)>, <蒙喩編 Mongyupyeon>, <字類註釋 Jalyujuseok>, <正蒙類語 Joengmongyueo> and <通學徑編 Tonghakgyeongpyeon>, seven foreign language study books such as <譯語類解 Yeokeoyuhae>, <譯語類解補編 Yeokeoyuhae-supplementary book>, <同文類解 Dongnunyuhae>, <蒙語類解 Mongeoyuhae>, <蒙語類解補編 Mongeoyuhae-supplementary book>, <倭語類解 Oaeeoyuhae> and <方言類釋 Bangeonyuseok>, and some vocabulary books <才物譜 Jaemulbo>, <廣才物譜 Kwangjaemulbo>, <物譜 Mulbo>, <物名攷 Mulmyeongko>, and <事類博解 Salyupakhae>. There are two kinds of synonyms with equal relationship that are spelled as more than two names for the same clothing. The first group was names that have different vocabularies for the same Chinese character headword, for example, Gyeokji and Namosin, Jeoguriot and Dongdolssi, Deungjige and Got dongot, Daloi and Nangja, Jitbidan and Oaedan, jusa and jeuusya, jusa and Murui, Muja and Heoja, and so on. The second group was names that are spelled with sound and meaning of Chinese character, for example, Nuyeok and Saui, Binhyeo and Jam, Mosi and Jyeopo, and so on. Also synonyms of Chinese names were found in equal relationship. Synonyms with connoting relationship in which one name perfectly connotes meaning of another name are Gotgal and Susik, Danryeong and Gwandae, Bosyeon and Chyeong, ete. In these cases, the range of the meaning of clothing terms can be confirmed since names with broad meaning connote names with narrow meaning. There are differences in use and form. In partial relationship synonym with the same name, some synonyms like Baji and Goui, and jeoksam and Hansam have difference in use, while Gamto, Got and Sarno, Neolku and Satgat, and Nangja and Cheopji have difference in form. These presented differences among similar names.

• 인터넷정보학회논문지
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• 제16권6호
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• pp.57-67
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• 2015

This paper proposes an Fuzzy-based Risk Reasoning Driving Strategy on VANET. Its first reasoning phase consists of a WC_risk reasoning that reasons the risk by using limited road factors such as current weather, density, accident, and construction, a DR_risk reasoning that reasons the risk by combining the driving resistance with the weight value suitable for the environment of highways and national roads, a DS_risk reasoning that judges the collision risk by using the travel direction, speed. and distance of vehicles and pedestrians, and a Total_risk reasoning that computes a final risk by using the three above-mentioned reasoning. Its second speed reduction proposal phase decides the reduction ratio according to the result of Total_risk and the reduction ratio by comparing the regulation speed of road to current vehicle's speed. Its third risk notification phase works in case current driving speed exceeds regulation speed or in case the Total_risk is higher than AV(Average Value). The Risk Notification Phase informs rear vehicles or pedestrians around of a risk according to drivers's response. If drivers use a brake according to the proposed speed reduction, the precedent vehicles transfers Risk Notification Messages to rear vehicles. If they don't use a brake, a current driving vehicle transfers a Risk Message to pedestrians. Therefore, this paper not only prevents collision accident beforehand by reasoning the risk happening to pedestrians and vehicles but also decreases the loss of various resources by reducing traffic jam.

• 한국잠사곤충학회지
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• 제47권1호
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• pp.1-4
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• 2005

오디 생산을 위한 재배법 개발을 위하여 원줄기 길이 1m로 하여 원가지를 3~5개 정도로 유지하는 중간만들기 수형으로 유지하였다. 이 때 뽕나무 재배에 적합한 식재거리는 2${\times}$1 m(500주/10a)로 하는 것이 2${\times}$1.5 m(333주/10a)에 비하여 주당수량은 약간 적으나 식재 주수가 많아 단위면적당 수량은 높은 것으로 나타났다. 원가지 길이를 30, 50, 70 및 90 cm로 한 경우 90 cm 처리구에서 오디의 수량이 가장 많았다. 원가지 길이별 주당 가지수는 원가지 길이가 길수록 가지수가 많았으며, 10a당 가지량 및 엽량은 일정한 경향을 보이지 않았다. 식재 거리별 주당 가지수는 식재거리가 넓을수록 가지수가 많았고, 10a당 가지량 및 엽량은 일정한 경향을 보이지 않았다.