Food Science of Animal Resources (한국축산식품학회지)

Korean Society for Food Science of Animal Resources (한국축산식품학회)
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Composition of Biologically Active Substances and Antioxidant Activity of New Zealand Deer Velvet Antler Extracts

  • Je, Jae-Young (School of Food Technology and Nutrition, Chonnam National University) ;
  • Park, Pyo-Jam (Department of Biotechnology, Kunkuk University) ;
  • Kim, Eun-Kyung (Department of Biotechnology, Kunkuk University) ;
  • Kim, Hyun-A (School of Food Technology and Nutrition, Chonnam National University) ;
  • Lim, Dong-Hwan (Shin Hung Pharm. Co.) ;
  • Jeon, Byong-Tae (Korean Nokyong Research Center, Konkuk University) ;
  • Ahn, Chang-Bum (School of Food Technology and Nutrition, Chonnam National University)
  • Published : 2010.02.28
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Abstract

Deer velvet antler was subjected to the extraction process using boiling water at three different temperatures (100, 110 and $120^{\circ}C$) and 70% ethanol solution. Functional components such as uronic acid, sulfated-glycosaminoglycans (sulfated-GAGs) and sialic acid in the extracts were analyzed, and their antioxidant activities were investigated using several in vitro models. Uronic acid and sulfated-GAGs content of each extract significantly decreased with increasing extraction temperature (p<0.05), while the residues obtained from the upper and middle part of the antler had a higher uronic acid content than the residues obtained from the base section. Sialic acid contents were highest in compounds extracted at $110^{\circ}C$, followed by 120 and $100^{\circ}C$. The 70% ethanol extracts also had a high levels of uronic acid content, but not for sulfated-GAGs and sialic acid. All extracts showed good antioxidant ability in a dose-dependant manner, with the $100^{\circ}C$ residue exhibiting the strongest activity compared to the 110 and $120^{\circ}C$ extracts. In relation to the hydroxyl radical scavenging activity and reduction power, the 70% ethanol extract exhibited the strongest activity. Furthermore, the velvet antler extracts inhibited apoptosis in hydrogen peroxide-induced PC-12 cells.

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References

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