• Journal of Microbiology and Biotechnology
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• v.18 no.3
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• pp.503-511
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• 2008

An edible marine red alga, Grateloupia filicina, collected from Jeju Island of Korea was hydrolyzed by cheap food-grade carbohydrases (Viscozyme, Celuclast, AMC, Termamyl, and Ultraflo) to investigate its anticoagulant activity. Among the tested enzymatic extracts of G. filicina, a Termamyl extract showed the highest anticoagulant activity. Anion-exchange chromatography on DEAE-cellulose and gel-permeation chromatography on Sepharose-4B were used to purify the active polysaccharide from the crude polysaccharide fraction of G. filicina. The purified sulfated polysaccharide (0.42 sulfate/total sugar) showed ${\sim}1,357kDa$ molecular mass and was comprised mainly of galactose(98%) and 1-2% of glucose. The sample showed potential anticoagulant activity on activated partial thromboplastin time (APTT) thrombin time (TT) assays. The purified G. filicina anticoagulant (GFA) inhibited the coagulation factor X (92%), factor II (82%), and factor VII (68%) of the coagulation cascade, and the molecular interaction (protein-polysaccharide) was highly enhanced in the presence of ATIII (antithrombin III). The dissociation constant of polysaccharide towards serine proteins decreased in the order of FXa (58.9 nM) >FIIa (74.6 nM) >FVII (109.3 nM). The low/less cytotoxicity of the polysaccharide benefits its use in the pharmaceutical industry; however, further studies that would help us to elucidate the mechanism of its activity are needed.

• Journal of Technologic Dentistry
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• v.37 no.4
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• pp.243-250
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• 2015

Purpose: The aim of this study was to investigate the shear bond strength between various commercial zirconia coping and veneering ceramic, and to observe the failure mode. Methods: For each zirconia block (iJAM Emerald, LUXEN Smile block, ICE Zirkon transluzent), 10 rectangular specimens were layered with Cercon ceram kiss, IPS e.max ceram, ICE Zirkon ceramic according to recommended by the manufacturer. The shear bond strength tests of the veneering porcelain to zirconia were carried out until fracture by a universal testing machine. After the shear bond tests, failure modes were characterized visually, under a stereomicroscope, such as adhesive, cohesive, or mixed. Data were analyzed with One-way ANOVA followed by Scheffe's tests. Results: The shear bond strength ($mean{\pm}SD$) of zirconia-veneer ceramic were JC group $13.9{\pm}3.6MPa$; JE group $17.7{\pm}2.4MPa$; JI group $15.1{\pm}2.5MPa$; LC group $9.5{\pm}1.5MPa$; LE group $16.2{\pm}2.3MPa$; LI group $12.6{\pm}0.8MPa$; ZC group $16.0{\pm}2.3MPa$; ZE group $18.5{\pm}3.4MPa$; and ZI group $15.3{\pm}3.2MPa$. The One-way ANOVA showed a significant difference between groups (p<0.05). The failure mode in most experimental groups was mixed failure, except for the LC group, which showed adhesive failure, and JE group, LE group and ZE group showed cohesive failure. Conclusion: For IPS e.max ceram, the shear bond strength value was highest for all kinds of zirconia blocks. For ICE Zirkon transluzent, the shear bond strength value was highest for all kinds of veneering ceramics. Most of experimental group interfaces revealed mixed failure mode.

• Food Science of Animal Resources
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• v.35 no.4
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• pp.507-514
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• 2015

Deer velvet antler (DVA) is one of the most popular medicines in China. Numerous studies have demonstrated that velvet antler possess biological effects. However, data regarding its anti-migration activity on prostate cancer is scarce. In this study, we investigated the inhibitory effect of top DVA (T-DVA) on the expression of prostate-specific antigen (PSA) and migration-related genes in the human prostate cancer cell, LNCaP. The T-DVA down-regulated the expression of PSA. In addition, the Radius^TM assay revealed that T-DVA inhibited the migration behavior of prostate cancer cells. Furthermore, the expression of matrix metalloproteinase (MMP)-9 and vascular endothelial growth factor (VEGF) was also decreased with T-DVA. On the contrary, T-DVA increased the tissue inhibition of metallo-proteinase (TIMP)-1 and (TIMP)-2. Taken together, our findings indicate that the T-DVA possesses anti-migration activity on prostate cancer cells. This is the first study of DVA to report the anti-migration activity on prostate cancer.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2010.04a
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• pp.448-452
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• 2010

The traditional Aids to Navigations(AtoN) have been ensuring the safety of ships by indicating the passage and dangers by depending on the flashing lights. But the more the industrial complex behind port which is all over the country involving the Ulsan port developed, the more the lights behind port is stronger, and then the distinguishment of the signal of AtoN from the lights behind port is more difficult. And It is urgently needed to prepare the counterplan about the ensurement of safety because the authorities levels up the limit tonnage of the ships which are sail in and out during night to improve the operation of port through reducing of the traffic jam So, the method of direct lighting like LED non-neon is applied to unmanned lighthouses or light beacon, and the LED flashing number plate is applied to light buoys whose light power is weaker than to improve distinguishment and to be easy positioning of ships. As a result, the users of Ulsan port comment favorably on this item and the development of AtoN must be continuos to overcome the lights behind port.

• Food Science of Animal Resources
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• v.30 no.1
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• pp.20-27
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• 2010

Deer velvet antler was subjected to the extraction process using boiling water at three different temperatures (100, 110 and $120^{\circ}C$) and 70% ethanol solution. Functional components such as uronic acid, sulfated-glycosaminoglycans (sulfated-GAGs) and sialic acid in the extracts were analyzed, and their antioxidant activities were investigated using several in vitro models. Uronic acid and sulfated-GAGs content of each extract significantly decreased with increasing extraction temperature (p<0.05), while the residues obtained from the upper and middle part of the antler had a higher uronic acid content than the residues obtained from the base section. Sialic acid contents were highest in compounds extracted at $110^{\circ}C$, followed by 120 and $100^{\circ}C$. The 70% ethanol extracts also had a high levels of uronic acid content, but not for sulfated-GAGs and sialic acid. All extracts showed good antioxidant ability in a dose-dependant manner, with the $100^{\circ}C$ residue exhibiting the strongest activity compared to the 110 and $120^{\circ}C$ extracts. In relation to the hydroxyl radical scavenging activity and reduction power, the 70% ethanol extract exhibited the strongest activity. Furthermore, the velvet antler extracts inhibited apoptosis in hydrogen peroxide-induced PC-12 cells.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.43 no.5 s.311
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• pp.19-27
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• 2006

Improvement in gait stability of fault-tolerant gaits for quadruped robots is addressed in this paper. The previously developed fault-tolerant gait gives a quadruped robot the ability to continue its walk against the occurrence of a leg failure. But it has a drawback of having marginal gait stability, which may lead to tumbling when the robot body's center of gravity is perturbed. To overcome such a drawback, a novel fault-tolerant gait is presented in this paper that generates positive stability margin against a locked joint failure, in which a joint of a leg is locked in a known place. Positive stability margin is obtained by adjusting foot positions of supporting legs between leg swing sequences. The advantages of the proposed fault-tolerant gait are discussed by comparing with the previous gait in terms of gait stability, stride length and gait velocity.

• Journal of the Korea Institute of Building Construction
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• v.7 no.1 s.23
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• pp.115-121
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• 2007

Ordinary concrete uses aggregate sufficiently soaked with water, and is weighed, mixed with other materials and placed in accord with performances required in the construction field. Recently special concrete with high fluidity and durability is required but it is difficult to use top-quality concrete due to lack of high-quality aggregate, delayed transportation because of traffic jam, etc. In addition, sometimes the use of a remicon is inevitable just for small-sized concrete constructions or it is difficult for a remicon to reach remote construction places such as mountainous areas. To solve these problems, this study attempted to pack concrete materials. In other words, it is to instantize concrete. This study dried aggregate, a material of concrete, and compared the change of absorption phase of the aggregate in water and in paste in order to examine the effect of the dryness of aggregate on its absorption rate and, based on the absorption rate, decided water addition ratio necessary for the reduction of unit quantity caused by the use of dry aggregate in designing concrete mixture, and analyzed the properties of unhardened concrete according to water addition ratio in manufacturing concrete using aggregate in the state of absolute dryness and in the state of surface dryness.

• Journal of the Korean Society of Costume
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• v.57 no.5 s.114
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• pp.140-150
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• 2007

The study aimed to classify the synonyms of clothing terms, such as equal relationship, connoting relationship and partial relationship. The subjects of the study are eleven Chinese character study books such as <石峰千字文 Seokbongcheonjamun> <丙子本千字文 Byeongjacheonjamun>, <註解千字文 Juhaecheonjamun>, <訓蒙字會 Hungmongjahoi>, <新增類合 Sinjeungyuhap>, <兒學編 Aahakpyeon(1816) (1908)>, <蒙喩編 Mongyupyeon>, <字類註釋 Jalyujuseok>, <正蒙類語 Joengmongyueo> and <通學徑編 Tonghakgyeongpyeon>, seven foreign language study books such as <譯語類解 Yeokeoyuhae>, <譯語類解補編 Yeokeoyuhae-supplementary book>, <同文類解 Dongnunyuhae>, <蒙語類解 Mongeoyuhae>, <蒙語類解補編 Mongeoyuhae-supplementary book>, <倭語類解 Oaeeoyuhae> and <方言類釋 Bangeonyuseok>, and some vocabulary books <才物譜 Jaemulbo>, <廣才物譜 Kwangjaemulbo>, <物譜 Mulbo>, <物名攷 Mulmyeongko>, and <事類博解 Salyupakhae>. There are two kinds of synonyms with equal relationship that are spelled as more than two names for the same clothing. The first group was names that have different vocabularies for the same Chinese character headword, for example, Gyeokji and Namosin, Jeoguriot and Dongdolssi, Deungjige and Got dongot, Daloi and Nangja, Jitbidan and Oaedan, jusa and jeuusya, jusa and Murui, Muja and Heoja, and so on. The second group was names that are spelled with sound and meaning of Chinese character, for example, Nuyeok and Saui, Binhyeo and Jam, Mosi and Jyeopo, and so on. Also synonyms of Chinese names were found in equal relationship. Synonyms with connoting relationship in which one name perfectly connotes meaning of another name are Gotgal and Susik, Danryeong and Gwandae, Bosyeon and Chyeong, ete. In these cases, the range of the meaning of clothing terms can be confirmed since names with broad meaning connote names with narrow meaning. There are differences in use and form. In partial relationship synonym with the same name, some synonyms like Baji and Goui, and jeoksam and Hansam have difference in use, while Gamto, Got and Sarno, Neolku and Satgat, and Nangja and Cheopji have difference in form. These presented differences among similar names.

• Journal of Internet Computing and Services
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• v.16 no.6
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• pp.57-67
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• 2015

This paper proposes an Fuzzy-based Risk Reasoning Driving Strategy on VANET. Its first reasoning phase consists of a WC_risk reasoning that reasons the risk by using limited road factors such as current weather, density, accident, and construction, a DR_risk reasoning that reasons the risk by combining the driving resistance with the weight value suitable for the environment of highways and national roads, a DS_risk reasoning that judges the collision risk by using the travel direction, speed. and distance of vehicles and pedestrians, and a Total_risk reasoning that computes a final risk by using the three above-mentioned reasoning. Its second speed reduction proposal phase decides the reduction ratio according to the result of Total_risk and the reduction ratio by comparing the regulation speed of road to current vehicle's speed. Its third risk notification phase works in case current driving speed exceeds regulation speed or in case the Total_risk is higher than AV(Average Value). The Risk Notification Phase informs rear vehicles or pedestrians around of a risk according to drivers's response. If drivers use a brake according to the proposed speed reduction, the precedent vehicles transfers Risk Notification Messages to rear vehicles. If they don't use a brake, a current driving vehicle transfers a Risk Message to pedestrians. Therefore, this paper not only prevents collision accident beforehand by reasoning the risk happening to pedestrians and vehicles but also decreases the loss of various resources by reducing traffic jam.

• Journal of Sericultural and Entomological Science
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• v.47 no.1
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• pp.1-4
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• 2005

As mulerry fruit has been increasingly evaluated as desirable for use in fresh and processed food and drink such as jam, juice and mulberry wine, opportunities for using the mulberry plant as a fruit sources have grown. With the demand for the mulberry fruits, mulberry fields for the production of mulberry fruits are increasing. To establish the mulberry cultivation methods for mulberry fruits production, effects of spacing and branch length on the productivity of mulberry fruits and growth of mulberry were studied.