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The Cytotoxic Effect of Oral Wet Wipes on Gingival Cells (시판 중인 구강청결티슈의 세포 독성 관찰)

  • Jung, Im-hee;Park, Ji Hyeon;Lee, Min Kyeng;Hwang, Young Sun
    • Journal of dental hygiene science
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    • v.18 no.2
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    • pp.76-84
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    • 2018
  • Wet wipes are being increasingly used because of their convenience. Particularly, oral wet wipes are useful for regular cleaning of a baby's mouth after birth. Therefore, the consumption of oral wet wipes has increased over the past few years and a variety of products are commercially available. However, product information on safety is not sufficiently provided and still raises doubts regarding adverse effects. To confirm the safety of wet wipes as an oral hygiene item and provide information for their use, we investigated the cytotoxicity of oral wet wipes and verified the underlying mechanism. The anti-bacterial effect of oral wet wipes was analyzed using the disk diffusion method. The cytotoxic effects of oral wet wipes were observed based on morphological changes using microscopy and determined using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay in gingival epithelial cells and gingival fibroblasts. Evaluation of apoptosis by oral wet wipes was explored using propidium iodide flow cytometric analysis and a terminal deoxynucleotidyl transferase (TdT)-mediated deoxyuridine triphosphate (dUTP) nick-end labeling (TUNEL) assay. Apoptosis-related molecules were also analyzed using western blotting. Five types of oral wet wipes were tested, and two products from Fisher-Price and Dr. Kennedy revealed strong cytotoxic effects on gingiva epithelial cells and gingiva fibroblasts, although they also showed intense anti-bacterial effects on oral bacteria. Cell cycle arrest in the G2/M phase and apoptosis were observed based on treatment of extracts from Fisher-Price and Dr. KENNEDY. Relatively high TUNEL levels, reduction of proliferating cell nuclear antigen and cyclin-dependent kinase 4 expression, and fragmentation of poly (ADP-ribose) polymerase were also elucidated. These results suggest that commercial oral wet wipes could exert cytotoxic influences on oral tissue, although there are anti-bacterial effects, and careful attention is required, especially for infants and toddlers.

Consumer's Perceptions of The Quality of Employee Foodservice in Pusan City and Kyeung Nam Provinces -By the Consumers' Characteristics- (부산 경남지역 산업체급식소의 급식 평가 연구 -급식대상자를 중심으로-)

  • Lee, Myung-Hae;Lyu, Eun-Soon;Kang, Hyeon-Ju;Ryu, Kyung
    • Journal of the Korean Society of Food Culture
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    • v.11 no.3
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    • pp.409-420
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    • 1996
  • Consumer's perceptions of the qualities of food and food-related services were surveyed through questionnaires by 672 adults randomly selected from 20 industrial foodservice in Pusan and Kyeung Nam area. The results are as follows: 1) By age, the elderly group gaved the highest mean score not only for freshness and temperature among the food characteristics but also for cleanliness of dishes and materials of dishes among the food-related service. 2) By occupation, the white collar worker group gaved the highest mean score in all characteristics of food and food-related service than did the blue collar worker group. Especially for courtesy of employees, the mean rating given by the white collar worker group was 3.15/5.00, but by the blue collar worker group was 2.67/5.00. 3) Good appetitive group rated taste of food 3.15/5.00, quality of food vs. food price 3.17/5.00, and freshness 3.15/5.00. But poor appetitive group rated taste of food 2.44/5.00, quality of food vs. food price 2.65/5.00, and freshness 2.70/5.00. 4) Men agreed that the rice and soup were right in amount. And women responded that the rice was in a large amount and the soup was not enough. 5) The white collar worker group agreed that the rice, the soup, the side dish, and the kimchi were right in amount. However the blue collar worker group agreed that the rice was right in amount, the soup and the side dish were not enough, and the kimchi was in a large amount. For seasoning of food, the white collar worker group responded that the salty taste and the hotness were just right. But the blue collar worker group responded that the food was neither salty nor hot at all. 6) The taste of food was shown to be positively correlated (p<0.001) with various food item combinations, freshness of food, and the variety of cooking methods.

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Consurmer's Recognition for the Label System and Policy of Environment-Friendly Agricultural Products (친환경 농산물의 인증제도 및 정책에 대한 소비자 인지도 조사연구)

  • Sin, Chul-Ro;Kim, Jin-Suk
    • Journal of agriculture & life science
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    • v.43 no.3
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    • pp.63-75
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    • 2009
  • The purpose of this study is to find out suggestions for government policy and expansion of consumption of environmental-friendly agricultural products(EFAP). For this purpose, we did research on purchasing pattern of EFAP and understanding of government environmental-friendly agricultural policy. First, the purchase of EFAP has been increased, because EFAP is safer. Consumers prefer department store because it is easier than any other marketing. Difficulties which consumers are facing when they purchase EFAP are price and credibility and small number of stores. Most favorable item is vegetable and the price of rice which consumers are willing to pay is really high. Second, not many consumers do recognize the label and system of EFAP. Third, most famous authentication institution agricultural products quality management service and other institutions are not recognized. Consumers recognize the certificate of origin. The government policy for safe food consumption is to intensify government supervision on foods. Suggestions from these results are as follow: First, the urgent problem to expand consumption of EFAP is credibility of EFAP. To make consumers trust EFAP, these are considered as useful solutions, i.e. recall, quality management service, standardization, and better quality. Second, government should be continue public relation, education and supervision of EFAP. Third, quality management should be continued. Not only central government but also local quality management institutions should continue quality management service. Last, local government should help farmers of EFAP to solve the difficulties of marketing.

Analyzing the Online Game User's Game Item Transacting Behaviors by Using Fuzzy Logic Agent-Based Modeling Simulation (온라인 게임 사용자의 게임 아이템 거래 행동 특성 분석을 위한 퍼지논리 에이전트 기반 모델링 시뮬레이션)

  • Min Kyeong Kim;Kun Chang Lee
    • Information Systems Review
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    • v.23 no.1
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    • pp.1-22
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    • 2021
  • This study aims to analyze online game user's game items transacting behaviors for the two game genres such as MMORPG and sports game. For the sake of conducting the analysis, we adopted a fuzzy logic agent-based modeling. In the online game fields, game items transactions are crucial to game company's profitability. However, there are lack of previous studies investigating the online game user's game items transacting activities. Since many factors need to be addressed in a complicated way, ABM (agent-based modeling) simulation mechanism is adopted. Besides, a fuzzy logic is also considered due to the fact that a number of uncertainties and ambiguities exist with respect to online game user's complex behaviors in transacting game items. Simulation results from applying the fuzzy logic ABM method revealed that MMORPG game users are motivated to pay expensive price for high-performance game items, while sports game users tend to transact game items within a reasonable price range. We could conclude that the proposed fuzzy logic ABM simulation mechanism proved to be very useful in organizing an effective strategy for online game items management and customers retention.

Research about muscle ache curer design development for hospital (병원용 근육통증 치료기 디자인 개발에 관한 연구)

  • Oh, Sung-Jin
    • Proceedings of the Korea Contents Association Conference
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    • 2006.11a
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    • pp.856-859
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    • 2006
  • Patient's position who muscle ache curer for hospital undergoes person entrance and treatment that take advantage of biological, physical force of low frequency and it is equipment that treat body muscle ache, but use equipment when use patient into compensation in hospital specially, that consider everybody is important first of all. This research question investigation with market survey of old product enforce because preference degree reflected officer a result and apply opinion tuned with product development connection engineers on DESIGN direction via typical product design development process close. This curer development research analyzed data involved directly taking advantage of FGI techniques with literature investigation collection. Investigation examined laying stress on muscle ache curer for hospital and a nurse than a doctor answered on question and purchase selection criterion or price portion to user focus. Direct market survey research that see item indicated by competition four provision shortcomings consequently in NEW MODEL development hereafter supplement and expectation. by contributing greatly in M/S security strategy hereafter because design development consisted for side that improve.

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Predictors of Local Legislators' Support for Tobacco Control Policies in Seoul Metropolitan City (서울특별시 기초의회 의원들의 흡연규제정책 지지도 및 관련 요인)

  • Lee, Weon-Young
    • Korean Journal of Health Education and Promotion
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    • v.22 no.2
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    • pp.77-95
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    • 2005
  • Objectives: This study measured the extent of local legislators' support for tobacco control policies and identified the predictors of that. Methods: Local legislators, from 21 Gu in Seoul Metropolitan City, underwent a self-administrated questionaire during the 6-week period from December 1, 2004 to January 15, 2005. Multiple linear regression model was used to assess relationships between five groups of variables(political factors including political ideology, personal characteristics, tobacco experiences, tobacco knowledge, contact with local health officers) and support for tobacco control policies based on an 11-item scale. Results: The rates of support for 'penalizing merchants who sell cigarettes to minors' and 'instituting a law mandating that parents should not smoke in a car when children are present' were highest as 87.5% and 82.0% respectively, and those for 'increasing price of cigarettes' and 'regulating stores that sell cigarettes' were lowest as 52.2% and 51.7% respectively. Support was higher among local legislators who thought government had a duty to promote healthy life styles, knew second-hand smoke could cause lung cancer, knew tobacco caused more deaths than alcohol. Support among ex-smokers and nonsmokers was higher than current smokers. Conclusions: The findings indicate that local legislators who oppose tobacco control measures may not be opposed to tobacco control per se, but are more generally opposed to a government role in health promotion, Thus, Tobacco control advocates need to be more attentive to the way tobacco control issues are framed for particular legislators. Further, they could work to increase tobacco knowledge among local legislators.

Development of Construction Cost Model through the Analysis of Critical Work Items (코스트 중요항목 분석을 통한 공사비 예측모델 연구)

  • Lee Yoo-Seob
    • Korean Journal of Construction Engineering and Management
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    • v.4 no.4 s.16
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    • pp.212-219
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    • 2003
  • In construction project planning and control, a cost model performs a critical role such as cost determination on a contract stage and cost tracing. The model can maximize owner's profit and value within the project budget and optimize cost management works on overall construction implementation stages. A BoQ(Bill of Quantities) generally adopted in a unit price contract has been applied as an important tool for cost control and forecast. However a previous cost model based on the BoQ has shown limitations in that it requires too detailed information and heavy manpower on cost management and difficulty in keeping relationship with construction planning, scheduling and progress management. The each cost items and unit prices which constitute of construction works are individually very important management factors but the relative weight for each items and prices have a difference on the contents and conditions of each conditions of each construction works. In consideration of this structural mechanism of cost determination, this research is aimed at examining the critical factors affecting the construction cost determination and propose and verify a new cost forecasting model which is more simple and efficient and also keeps the accuracy of cost management.

A Study on the Consumer Perception and Factor Analysis of Food Tourism (음식관광에 대한 소비자의 인식 및 요인분석)

  • Kim, Eun-Hae;Lee, Min-A
    • Korean Journal of Community Nutrition
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    • v.15 no.1
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    • pp.83-93
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    • 2010
  • The purpose of this study is to investigate consumer perception and importance of food tourism properties and performance of the properties in Sangju province of Gyeongsangbuk-do. The study has found that persons who have food tourism experiences (75 persons, 50.7%) had slightly more than not experience persons (72 persons, 48.6%). Additionally, most of the respondents were usually satisfied with the local foods. Also, it was found that food tourism had been taken 1-2 times per 6 months (48 persons, 64.0%) on average, and 135 persons (91.2%) had intention of experiencing food tourism. According to the result of Importance-Performance Analysis (IPA) on consumers' food tourism properties, high importance was on 'There are attractive landscapes.' ($4.52\;{\pm}\;0.56$), 'Accommodations with reasonable price.' ($4.18\;{\pm}\;0.80$), and 'The food of the area is famous.' ($4.15\;{\pm}\;0.73$); and the properties such as 'There are local specialty shops or markets selling local produce.' ($3.03\;{\pm}\;0.83$), 'The climate is temperate.' ($3.03\;{\pm}\;0.87$), and 'There are attractive landscapes.' ($3.02\;{\pm}\;0.98$) showed average performance. A factor analysis about consumers' importances to the food tourism properties shows that the factors were divided into four kinds and each of the factors were named as 'convenience-stable propensity', 'valued-oriented propensity', 'adventurous-aggressive propensity' and 'traditional-active propensity'. Variance ratios of each factor were 22.319%, 10.286%, 8.723% and 6.239%, respectively. According to the result of a reliability analysis, Cronbach's alpha value was 0.8621, implying that reliability of each item was very high. Therefore, it is considered that development of food tourism products and promotion strategies therefore should be designed based on the importance of food tourism properties hereafter.

The Comparison of Fabric Images between On-line and Off-line by Fabric Types and Characteristics (직물의 종류와 특성에 따른 온라인과 오프라인에서의 의복소재 이미지 비교)

  • Kim, Hee-Sook;Cho, Shin-Hyun
    • Korean Journal of Human Ecology
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    • v.13 no.5
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    • pp.787-798
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    • 2004
  • This research was designed to compare clothing fabric images between on- and off-line by fabric types and its characteristics. 125 subjects who have a fashion design major evaluated the fabric image of various 16 kinds of specimens on- and off-line. Frequency, x2-test, t-test, and Pearson correlation were used for statistical analysis by SPSS WIN 11.0. The results of this study are as follows: 1. The advantage of on-line shopping includes low price and purchasing convenience, etc. On-line shoppers mostly purchase clothing items, such as T-shirt and slacks. In most cases, texture of fabrics provides a main cause for the shoppers' discontentment with internet shopping. 2. The results of t-test for the difference of the evaluation score show that plain or pile weave and highly thick or thin fabrics-for example, Organdy, Corduroy, Nylon Taffeta, Plush, etc.-have a large difference between on-and off-line image. On the other hand, medium-thick twill weave-for example, Tweed, Flannel, etc.-or patterned weave-Chiffon, Dobby fabric, etc.-shows a small difference. 3. The results of correlation of the evaluation score indicate that wool twill fabrics like Tweed, Saxony, and Polafleece show a high correlation between two kinds of evaluation score. In texture preference, no correlation exists between on-line and off-line. 4. With an analysis on fabric image evaluation by fabric characteristics, smooth, shiny pink Satin was found the most positively-evaluated item in all evaluation fields except in pattern preference and individuality. On the other hand, thick olive green Corduroy was evaluated most negatively in the fields of elegance, luxury, and feminine. 5. When compared with real ones, thin fabrics provide a different on-line fabric image. For example, Nylon Taffeta and Organdy were evaluated positively on-line because of luster and pastel tone color. However, lusterless uneven cotton Seersucker was evaluated negatively. 6. Real fabrics preference is more negative than on-line ones. In addition, patterned or unique fabrics display a high agreement between the two kinds of images.

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A Study on Recognition, Utilization of Food and Nutrition Labelling of Elementary School Students (초등학생의 식품영양표시에 대한 인식 및 이용실태)

  • Oh, Sae-Hyun;Lee, Yang-Soon
    • Korean Journal of Human Ecology
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    • v.19 no.6
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    • pp.1083-1094
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    • 2010
  • The purpose of this study is to provide a fundamental research data that is necessary in an education of dietary life so that the students have sound dietary life through a right food purchase after investigating perception of children's dietary habit and activity, food labelling, and nutrition labelling for 400 students of the 5 and 6th grades. The result of the study are as followings. In terms of perception questions over food labelling, on the whole, "know it little bit" was the highest. Girls and country was higher than boys and city. A list of item that is important in contents of food labelling were period of circulation, data of manufacturing, price, used ingredient, origin of product, nutrition contain labelling, manufacturer, quantity in contents(quantity, the number). A meaningful difference was shown in gender(p<.05) and area(p<.01). In 30 perception questions over nutrition labelling, "know it little bit" was the most, and girls and country were higher than boys and city. In ascertaining nutrition labelling at the time of purchasing the food, "look often" was the most. Girls and city were higher than boys and Gun in average but no difference was statistically shown in knowledge mark in utilization and perception of nutrition labelling. The response rate in girls(p<.01) and country(p<.05) was higher in a question of "if nutrition labelling is displayed, nutriment that is harmful for our body will be eaten less" and girls' response rate was higher in the question of "being educated for my health". Therefore, practice centered nutrition education is necessary to purchase the food after ascertaining food nutrition labelling out of an attitude in habitually purchasing the processed food. The students develop comprehensible food nutrition labelling the direction to emphasizing nutrition educational labelling and recognizing that the healthy nutriment is contained without conventional and food safety centered labelling should be changed.