• 대한시과학회지
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• 제20권4호
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• pp.543-551
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• 2018

목적 : 각막굴절교정수술 후 각막절삭량에 따른 안압변화와 수술 전 굴절이상도에 따른 수술 후 안압 변화에 대하여 알아보고자 하였다. 방법 : 라식 각막굴절교정수술을 받은 평균연령 $37.34{\pm}7.42$세, 성인 남녀 108명(남자 48명, 여자60명)을 대상으로 선정하였다. 자동굴절검사기, 비접촉형안압계, 엑시머레이저를 이용하여 굴절이상도, 안압, 각막절삭량을 측정하였으며, p<0.05일 때 통계적으로 유의하다고 판단하였다. 결과 : 각막굴절교정수술 전 안압은 남자가 $15.08{\pm}2.60mmHg$, 여자가 $14.16{\pm}2.67mmHg$로 남자가 여자보다 높게 나타났으며, 각막굴절교정수술 후 안압 감소량은 남자가 4.22mmHg, 여자가 3.61mmHg로 나타났다. 등가구면 굴절력은 각막굴절교정 수술 전 남자 $-3.89{\pm}2.17D$, 여자 $-4.45{\pm}2.92D$에서, 각막굴절교정 수술 후 남자 $-0.10{\pm}0.46D$, 여자$-0.04{\pm}0.46D$로 나타났다. 각막굴절교정수술 후 각막절삭량은 남자 $53.95{\mu}m$, 여자 $61.26{\mu}m$로 통계적으로 유의한 차이가 있었으며, 각막절삭량과 안압의 감소량에는 유의한 상관성(r=0.2299, p<0.001)을 보였다. 성별로는 남자의 각막절삭량이 많아질수록 안압의 감소량은 유의하게 증가하는 것으로 나타났다. 굴절이상도가 증가할수록 안압의 감소량도 커져 경도의 굴절이상도에서는 $3.04{\pm}2.18mmHg$, 중등도의 굴절이상에서는 $4.10{\pm}2.16mmHg$, 고도의 굴절이상도에서는 $4.65{\pm}3.29mmHg$가 감소하는 것으로 나타났다. 결론 : 각막굴절교정수술 후 비접촉식 안압계로 측정한 안압은 감소하는 것을 알 수 있었으며, 안압측정은 녹내장 판단에 영향을 줄 수 있으므로 안압 측정시 각막굴절교정수술 여부에 대한 사전설문이 필요할 것으로 생각된다.

• 생명과학회지
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• 제17권11호
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• pp.1472-1476
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• 2007

본 연구는 정상적인 안압을 가진 비글견에서 4가지의 다른 농도를 가진 lidocaine을 사용하여 앞쪽목신경절차단 후 안압의 변화를 관찰하기 위하여 시행하였다. 실험군은 전향적 교차시험으로 10두의 비글견을 2%, 1%, 0.5% 및 0.25% lidocaine group으로 4군으로 나뉘었다. 모든 실험견들은 4 가지의 다른 농도를 가진 2 ml의 lidocaine을 사용하여 각 4번의 앞쪽목신경절 차단을 받았으며 신경 차단은 무작위로 1주일 간격으로 각각 시행되었다. 실험결과 호르너 증후군은 모든 실험군에서 관찰되었다. 1% lidocaine group에서는 대조군과 비교하여 차단 후 5분에서 안압의 유의한 상승이 있었으며(p<0.05), 2%와 1% lidocaine group의 안압은 앞쪽목신경절 차단 후 25분과 45분 사이 감소하였으나, 0.5%와 0.25% lidocaine group은 변화가 없었다. 이상의 결과를 종합하면, 앞쪽 목신경절 차단술은 정상 안압의 변화에 영향을 미치며 0.5%와 0.25% lidocaine은 안압을 변화시키기에는 부적당한 농도로 사료된다.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2010년도 추계학술대회 논문집
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• pp.103-104
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• 2010

• Journal of Preventive Medicine and Public Health
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• 제44권4호
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• pp.157-166
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• 2011

Objectives: This study was conducted to show the intraocular pressure (IOP) distribution and the factors affecting IOP in subjects with type 2 diabetes mellitus (DM) in India. Methods: We measured the anthropometric and biochemical parameters for confirmed type 2 DM patients. A comprehensive ocular examination was performed for 1377 subjects aged > 40 years and residing in Chennai. Results: A significant difference in IOP (mean ${\pm}$ standard deviation) was found between men and women ($14.6{\pm}2.9$ and $15.0{\pm}2.8$ mmHg, p = 0.005). A significantly elevated IOP was observed among smokers, subjects with systemic hypertension and women with clinically significant macular edema (CSME). After a univariate analysis, factors associated significantly with higher IOP were elevated systolic blood pressure, elevated resting pulse rate and thicker central corneal thickness (CCT). In women, elevated glycosylated hemoglobin was associated with a higher IOP. After adjusting for all variables, the elevated resting pulse rate and CCT were found to be associated with a higher IOP. Conclusions: Systemic hypertension, smoking, pulse rate and CCT were associated with elevated intraocular pressure in type 2 DM. Women with type 2 DM, especially those with CSME, were more prone to have an elevated IOP.

• 식품보건융합연구
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• 제4권2호
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• pp.13-16
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• 2018

Acupuncture has been clinically used to treat patients suffering from eye disease. It has been used in efforts to help preserve vision for those with a wide range of eye conditions including glaucoma and intraocular hypertension. High intraocular pressure (IOP) is usually associated with glaucoma and conventional treatment is focused on lowering IOP. Controlling this risk factor should help hasten the onset of glaucoma for those patents that are suspect or borderline candidates for glaucoma. In review of the limited scientific research there are not many studies that support conclusive evidence for the use of acupuncture on eye diseases and particularly glaucoma and ocular hypertension. For the information that does exist, diverse results from various interventions make it difficult to draw clear conclusions. The existing studies use different acupoints, techniques, frequencies, and durations. Individual treatment strategies according to the practitioner's subjective experience, patient condition, and the use of other complimentary and natural strategies is ideal for taking a more dynamic and wholistic approach to getting results. Until more pragmatic research models are funded and implemented, case reports can offer good examples of experiential and objective outcomes. This case report presents a 61 year old healthy female patient diagnosed with open-angle borderline glaucoma with elevated IOP. The patients IOP was successfully reduced with 12 treatments over three months using scalp electro-acupuncture and distal Master Tung points.

• 한국동물위생학회지
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• 제25권1호
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• pp.87-96
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• 2002

In this study, we wanted to determine if the respirotropic JMK strain of infectious bronchitis virus(IBV), which has a spike glycoprotein gene that is 99% similar to the nephropathogenic Gray strain of IBV, could adapt and cause lesions in the kidney following intracloacal passage in chickens. Two day old specific pathogen free(SPF) cchickens were infected with Gray and JMK strains by the intraocular and cloacal route. Several tissue samples were collected at various times. Viruses were recovered from more tissues and earlier in the infection from chickens infected cloacally than chickens infected intraocularly. Virus was isolated from the kidney of chickens infected with Gray by the intraocular route and JMK by the intracloacal route, but not from chicken given JMK the intraocular route. Histopathologically, interstitial nephritis was observed in Gray infected chickens. However, viral RNA or antigen were not detected in the kidney by in situ hybridization and immunohistochemistry. We further passaged the JMK strain ten times in two day old SPF chickens using cloacal inoculation. We examined the virus titer and histopathological change in the kidney at each passage level. The amount of virus recovered from the kidney was stable throughout this serial passage and the passaged virus did not caused renal damage. Further, virus could not be isolated from the kidney when chickens were infected with the passaged virus by the intraocular route. We conclude that the JMK strain has a strict upper respiratory tract tropism since cloacal passage did not produce nephrotropism or nephropathogenicity.

• Journal of Korean Biological Nursing Science
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• 제21권1호
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• pp.12-21
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• 2019

Purpose: The purpose of this study was to review previous literature with an aim to explore the sleep disturbance level after a patient undergoes cataract surgery using an integrative review. Methods: We used the key words, 'cataract surgery', 'sleep', and 'intraocular lens' to find peer-reviewed publications in seven databases. Among 450 searched articles, eight articles were selected after exclusion of articles that did not meet the criteria. Results: Five of the articles submitted that subjective sleep quality of the patients with blue-filtering intraocular lens (BF-IOL) implant improved as compared to that before surgery. The change of saliva melatonin concentration after BF-IOL implant did not coincide in two of the articles. Two of the articles reported an increased level of intrinsically photosensitive retinal ganglion cells response after BF-IOL implantation. Conclusion: The published studies stated that BF-IOL implant did not have any negative impact on quality of sleep among cataract patients suffering with poor sleep. Rregardless of intraocular lens type, cataract surgery may increase photoreception of intrinsically photosensitive retinal ganglion cells one year after surgery although the mechanism was not clear. It is necessary to identify various factors influencing the quality of sleep such as gender and activities among cataract patients with BF-IOL implant in the future.

• Parasites, Hosts and Diseases
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• 제50권1호
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• pp.73-78
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• 2012

We report a case of intraocular gnathostomiasis diagnosed by western blot assay in a patient with subretinal tracks. A 15-year-old male patient complained of blurred vision in the right eye, lasting for 2 weeks. Eight months earlier, he had traveled to Vietnam for 1 week and ate raw wild boar meat and lobster. His best-corrected visual acuity was 20/20 in both eyes and anterior chamber examination revealed no abnormalities. Fundus examination showed subretinal tracks in the right eye. Fluorescein angiography and indocyanine green angiography showed linear hyperfluorescence of the subretinal lesion observed on fundus in the right eye. Ultrasound examination revealed no abnormalities. Blood tests indicated mild eosinophilia (7.5%), and there was no abnormality found by systemic examinations. Two years later, the patient visited our department again for ophthalmologic evaluation. Visual acuity remained 20/20 in both eyes and the subretinal tracks in the right eye had not changed since the previous examination. Serologic examination was performed to provide a more accurate diagnosis, and the patient's serum reacted strongly to the $Gnathostoma$ $nipponicum$ antigen by western blot assay, which led to a diagnosis of intraocular gnathostomiasis. This is the first reported case of intraocular gnathostomiasis with subretinal tracks confirmed serologically using western blot in Korea.

• Journal of Trauma and Injury
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• 제22권1호
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• pp.97-102
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• 2009

Purpose: Blunt trauma can cause a wide range of ocular injuries. This study was performed to describe the prevalence of severe intraocular injuries (SIOI) and their correlation with the severity of blunt orbital trauma. Methods: We retrospectively analyzed 117 eyes of 107 patients with orbital wall fractures who visited the emergency room at Konyang University Hospital from July 2006 to June 2008. Clinical features such as age, sex, causes of injury, revised trauma score (RTS), type of orbital wall fractures were recorded. The patients were divided into two groups: blowout fracture with severe intraocular injuries (SIOI) and blowout fracture without SIOI. We compared the clinical and the injury-related characteristics between two groups and analyzed the SIOS-related factors. Results: Among the 107 patients (117 eyes) with blowout fractures, 29 (27.1%) patients with 32 eyes (25.6%) had complicated severe intraocular injuries. Retrobulbar hemorrhage (14.5%), hyphema (13.7%), traumatic optic nerve injury (4.3%), and sustained loss of visual acuity (4.3%) were the most common SIOI disorders. A logistic regression analysis revealed that loss of visual acuity (odds ratio = 4.75) and eyeball motility disorder (odds ratio=7.61) were significantly associated with SIOS. Conclusion: We suggest that blowout fracture patients with loss of visual acuity or eyeball motility disorder are mostly likely to have severe intraocular injuries, so they need an ophthalmologic evaluation immediately.

• 한국안광학회지
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• 제11권2호
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• pp.91-97
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• 2006

한국인 청년 남, 여 1,027명(남자=475, 여자=552)을 대상으로 안압의 상대 빈도 분포를 조사하였다. 상대적 빈도의 최고값은 남, 여에서 각각 14.5mmHg와 17.5mmHg이었으며, 전체 안압 빈도 분포범위는 남, 여에서 각각 7~23mmHg와 7~22mmHg이었다. 그리고 누적 빈도 중앙값 (누적빈도=0.5)은 남, 여에서 각각 13.0~16.5mmHg와 16.5~18.5mmHg로 여자가 남자 보다 더 높았다. 평균 안압은 남, 여에서 각각 15.2mmHg와 15.8mmHg이었고 조사 대상의 98%가 정상 안압의 범위에 속했다. 안압은 일차 변동을 나타냈는데 아침에서 저녁으로 가면서 감소하는 추세를 보였다. 안압 변동의 추세선을 보면 운동에 의해 안압이 감소되었으며 넥타이를 맨 경우와 누워있는 자세를 유지하는 동안 안압은 추세적으로 증가되었다.