• 한국수산과학회지
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• 제32권5호
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• pp.642-648
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• 1999

감성돔, Acanthopagrus schlegeli의 소화관은 식도, 위, 장, 항문 그리고 위의 유문부 말단에서 유래한 4$\~$5개의 맹낭 형태인 유문수로 이루어져 있었다 어체 체장에 대한 식도에서 항문까지의 소화관 길이의 비 (RLG: relative length of gut)는 1.04(n=10)였다. 소화관의 조직층은 장막, 근육층, 점막하층, 점막층으로 구성되는데, 점막하층의 발달은 전체적으로 매우 미약했다. 식도 점막주름의 형태는 규칙적인 분지형이었으며, 점막근층은 아주 잘 발달되어 있었다. 점막상피층은 입방형 또는 원주형 상피세포와 점액분비세포로 구성되며, 상피세포의 자유면에서 미세융모의 관찰은 어렵다. 위점막주름의 형태는 규칙적인 미분지형이며, 위의 근육충과 점막근층은 잘 발달되어 있었다. 점막충의 표면상피에서는 미세융모가 관찰되며, 위선과 분비과립은 체부에서 가장 잘 발달되어 있었다 유문수와 장의 점막주름은 불규칙한 분지형이다 장은 점막주름의 길이와 조직학적인 특징에 의해 전장부, 중장부, 후장부의 구분이 가능하였다. 유문수와 장의 선조연과 배상세포는 후장부에서, 영양분흡수세포는 중장부에서 가장 발달된 양상을 보였다.

• 한국패류학회지
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• 제22권1호
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• pp.87-95
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• 2006

본 연구에서는 남극삿갓조개 (Nacella concinna) 의 장 (intestine)의 중금속 농축에 관하여 알아보고자 카드뮴 노출실험을 실시한 후 중금속에 노출 시 동물체내에서 유도되는 단백질 중의 하나인 metallothionein을 면역조직화학적 방법으로 추적하고 투과전자현미경 (transmission electron microscope) 을 이용하여 세포의 미세구조의 변화를 알아보았다. 더불어 SEM-EDS 장비를 이용한 원소분석을 통해 중금속의 분포를 알아보아 중금속의 축적 및 해독기작에 대한 기초자료를 얻고자 수행되었다. Metallothionein의 분포를 살펴보기 위하여 면역조직화학적 실험이 수행된 바, 중금속이 농축되고있는 삿갓조개의 장상피세포의 첨단부에 metallothionein이 많이 존재하고 있음을 알 수 있었으며, 미세구조 관찰결과 노출시간이 경과함에 따라 핵막의 팽창, whorl 구조의 출현, 핵 내 봉입체를 관찰할 수 있었다. SEM-EDS 관찰결과 카드뮴 노출결과, 황이 급격하게 줄어들었고, 칼슘과 아연이 상대적으로 증가하는 양상을 관찰 할 수 있었다. 이상에서와 같이 Cd 노출의 정도에 따라 비교적 빠른 세포반응을 보이는 남극삿갓조개의 특징은 자연 상태에서 Cd의 노출에 따른 효과적인 생물 지표종으로서 가치가 있는 것으로 사료된다.

• Journal of Ginseng Research
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• 제45권5호
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• pp.583-590
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• 2021

Background: Gintonin, isolated from ginseng, acts as a ginseng-derived lysophosphatidic acid (LPA) receptor ligand and elicits the [Ca²⁺]_i transient through six LPA receptor subtypes (LPARSs). However, the long-term effects of gintonin-enriched fraction (GEF) on the gene expression of six LPARSs remain unknown. We examined changes in the gene expression of six LPA receptors in the mouse whole brain, heart, lungs, liver, kidneys, spleen, small intestine, colon, and testis after long-term oral GEF administration. Methods: C57BL/6 mice were divided into two groups: control vehicle and GEF (100 mg/kg, p.o.). After 21-day saline or GEF treatment, total RNA was extracted from nine mouse organs. Quantitative-real-time PCR (qRT-PCR) and western blot were performed to quantify changes in the gene and protein expression of the six LPARSs, respectively. Results: qRT-PCR analysis before GEF treatment revealed that the LPA6 RS was predominant in all organs except the small intestine. The LPA2 RS was most abundant in the small intestine. Long-term GEF administration differentially regulated the six LPARSs. Upon GEF treatment, the LPA6 RS significantly increased in the liver, small intestine, colon, and testis but decreased in the whole brain, heart, lungs, and kidneys. Western blot analysis of the LPA6 RS confirmed the differential effects of GEF on LPA6 receptor protein levels in the whole brain, liver, small intestine, and testis. Conclusion: The LPA6 receptor was predominantly expressed in all nine organs examined; long-term oral GEF administration differentially regulated LPA3, LPA4, and LPA6 receptors in the whole brain, heart, lungs, liver, kidneys, small intestine, and testis.

• 약학회지
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• 제32권3호
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• pp.194-197
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• 1988

We measured the rate of water transfer across the isolated small intestine of the rat in Wiseman apparatus using tritiated water ($^3H_2O$) in drinking beverages such as electrolytes solution, fruit juice, carbonated water and barley water. Initial transfer rate of water using four beverages were determined: Electrolytes solution is the fastest and followed by barley water, carbonated water and fruit juice.

• 한국환경성돌연변이발암원학회:학술대회논문집
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• 한국환경성돌연변이발암원학회 2003년도 추계학술대회
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• pp.155-156
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• 2003

• 한국환경성돌연변이발암원학회:학술대회논문집
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• 한국환경성돌연변이발암원학회 2003년도 추계학술대회
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• pp.158-159
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• 2003

• 한국임상수의학회지
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• 제5권2호
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• pp.101-106
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• 1988

A partial obstruction of small intestine was diagnosed by physical and radiographic examination in a dog which had signs of anorexia, vomiting, diarrhea and dehydration The dog was treated by surgical method. String-like foreign body was located from stomach to upper jejunum. Diffuse laceration, inflammation and perforation caused by foreign body were observed in intestine. Intestinal resection was carried out to remove the foreign body from upper duodenum to upper jejunum. The dog was convalesced successfully after operation.

• 한국식품영양과학회지
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• 제11권4호
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• pp.43-46
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• 1982

The purpose of this paper was to study the effect of surfactants on the absorption and the bioavailability of ascorbic acid in the small intestine of rats and rabbits absorption of ascorbic acid in small intestine of rats was increased with tween 80 and span 80.The blood level of ascorbic acid in rabbits was elevated by combined with low concentration of surfactants but high concentration of surfactants. The bioavailability of ascorbic acid was increased by simultaneous administration of surfactants.

• Journal of Chest Surgery
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• 제25권5호
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• pp.544-549
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• 1992

Carcinoid tumors can be ubiquitous, but most will originate in four sites: appendix [38%], small intestine[24%], rectum[13%] or bronchus[11.6%]. And bronchial carcinoids are rare, accounting for only 1% to 6% of all primary lung tumors. Familial adenomatous polyposis cali, the most common form of the polyposis syndromes attributable to a genetic defect, is defined by demonstration of at least 100 adenomatous polyps in the large intestine. We experienced a case of typical bronchial carcinoid with familial adenomatous polyposis cali in 23 year old female patient, which was surgically treated by left lower lobectomy.

• 사상체질의학회지
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• 제24권4호
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• pp.1-16
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• 2012

Objectives : We aimed to analyze the meanings of the energy and fluid metabolism in the Discourse on Viscera and Bowels of Donguisusebowon, and to find the clues for the explanation of the pathology and symptomatology of Taeeumin. Methods : The Discourse on Viscera and Bowels of Donguisusebowon was reviewed and examined for relevant information on the energy and fluid metabolism from the structural and the functional point of view respectively. And, based on the derived meanings of the energy and fluid metabolism, the pathology and symptomatology of Taeeumin were analyzed. Results and Conclusions : 1. The meanings of the energy and fluid metabolism can be explained by the different attributes of the energy and fluid produced from the esophagus and the small intestine, and the different function of exhaling-dispersing and inhaling-concentrating in the different tract of circulation such as Lung affiliation (esophagus, skin, ear and lung) and Liver affiliation (small intestine, flesh, nose and liver). 2. The Exterior disease of Taeeumin starts with the weakness of exhaling-dispersing function at the skin, and leads to the dysfunction of the esophagus and the lung sequently. The dysfunction of the lung aggravates that of the skin and the esophagus. 3. The Interior disease of Taeeumin begins with excess of the inhaling-concentrating functions at the flesh and the small intestine, and leads to the dysfunction of the lung, which induces the dysfunction of exhaling-concentration at the skin and esophagus. And, this disparities between exhaling-dispersing and inhaling-concentrating functions exasperate the problem at the flesh and the small intestine.