• Research in Community and Public Health Nursing
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• v.17 no.4
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• pp.461-471
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• 2006

Purpose: The Purpose of this study was to evaluate the effects of antioxidant vitamins and minerals supplementation on blood pressure and lipids in the elderly with hypertension. Methods: This study adopted a unequivalent control group pretest-posttest design. For this study, 79 subjects with hypertension were selected among the home visiting clients of public health centers. The experimental group received 12-weeks' treatment with antioxidant vitamin A, C, E, carotene, magnesium and selenium and the control group did not take any antioxidant vitamin and mineral. Results: There were statistical differences in systolic blood pressure and diastolic blood pressure between the experimental group and the control group after the intervention. In the experimental group, systolic blood pressure decreased from 145.4mmHg before the intervention to 135.7mmHg after the intervention, and diastolic blood pressure decreased from 88.3mmHg before the intervention to 81.9mmHg after the intervention. However, there were no statistical differences in total cholesterol and triglyceride between the experimental group and the control group after the intervention. Conclusions: A short-term supplementation with antioxidant vitamins & minerals can reduce blood pressure in the elderly with hypertension. The continuous effects of the supplementation and its beneficial effects on the prevention of cardiovascular diseases still need to be studied further.

• Journal of muscle and joint health
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• v.25 no.3
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• pp.205-217
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• 2018

Purpose: The purpose of this review was to analyze the characteristics and effectiveness of online-based intervention for infertile women. Methods: We established the PICO (Participant-Intervention-Comparison-Outcome) strategy and conducted a systematic review of 7 literatures retrieved from 3 electronic databases of Ovid-Medline, Ovid-Embase, and the Cochrane Library. Two investigators independently extracted the data and assessed the quality of included studies using Cochrane risk of bias. Results: The pregnancy outcome showed that higher total risk scores (TRS) about lifestyle behavior was significantly associated with lower chance of pregnancy (aHR 0.79, 95% CI 0.72~0.85). Stress was significantly decreased in experimental groups receiving online-based interventions (p<.05). Depression score was significantly lower in groups receiving additional interventions besides on-line interventions than those who used online-based intervention only. The other outcomes, including anxiety, self-efficacy, helpfulness of intervention, perceived social support, and knowledge scores were not significantly different within and between groups in overall. Characteristics of the interventions were heterogeneous. Conclusion: There is evidence that online-based intervention in infertile women enhances the pregnancy and reduces stress levels.

• Journal of Korean Biological Nursing Science
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• v.21 no.2
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• pp.99-107
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• 2019

Purpose: The purpose of this study was to determine the current status of obesity intervention programs, and its effects on endothelium function in adolescents. Method: This was a descriptive research study, that investigated domestic and international literature 2009-2018. Using databases inside and outside of Korea to search for 'adolescent', 'obese adolescent', 'exercise', 'program', or 'intervention', and 'endothelium function', a total of 14 literature have been selected for 6 domestic research and 8 international research, excluding overlapping, case studies, literature reviews, and unrelated studies. Results: Interventions for enhancing endothelium function were exercise program, diet, vitamin D3 treatment, and Orlistat intake relative to international research, and combined exercise and purple sweet potato intake, in most domestic research. Dependent variables included FMD, RHI, NMD, EPCs, and EMPs, for measuring endothelium function in international research, and PWV, FMD and RHI, in domestic research. Conclusion: Results of this study confirmed that application of obese intervention programs, may improve endothelium function in adolescents. Further studies are required, to develop nursing intervention, that would enhance endothelium function in adolescents.

• Journal of Yeungnam Medical Science
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• v.38 no.4
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• pp.282-288
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• 2021

Medication alone is not sufficient to treat insomnia. In addition, the side effects of sleep medications themselves cannot be ignored during treatment. Insomnia begins with poor sleep quality and discomfort, but as it continues, patients fall into a vicious circle of insomnia with negative thoughts and dysfunctional and distorted perceptions related to sleep. Mindfulness-based intervention for insomnia corrects these sequential cognitive and behavioral processes. The mindfulness technique basically recognizes all the thoughts, feelings, and experiences that occur to us as they are, nonjudgmentally, and then trains them to return to the senses of our body. In this way, while noticing all the processes of the sequential vicious cycle and training them to return to our bodies (e.g., breathing), mindfulness determines whether we are really sleepy or just fatigued. This mindfulness-based intervention can be a useful nonpharmaceutical intervention for insomnia, and its stability and efficacy has been proven by many studies.

• Therapeutic Science for Rehabilitation
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• v.7 no.2
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• pp.17-27
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• 2018

Objective : The purpose of this study was to investigate the effect of occupational therapy intervention using a fully immersive virtual reality device on the upper extremity function of patients with chronic stroke. Methods : This study used a single subject (ABA) design. The study subjects was a chronic stroke patient with left lateral deviation. Four baseline periods, 12 intervention periods, and 4 baseline regression periods were performed for a total of 20 sessions for 10 weeks. OT intervention with a fully immersive virtual reality device was used every 30 minutes. BBT and WMFT evaluations were performed at each session and the results were displayed in a line graph. Results : The patient's upper limb function has improved. During baseline recurrence, efficacy of treatment was confirmed after removal of intervention, but no significant changes were observed. Conclusion : It has been found that OT intervention with a fully immersive virtual reality device for upper limb function in chronic stroke patients is an effective intervention. However, the effectiveness of maintaining treatment is not important, so we need to develop an easy-to-use home intervention program.

• The Journal of Korean Physical Therapy
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• v.22 no.4
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• pp.65-71
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• 2010

Purpose: The aim of this study was to describe the effects of conservative treatment intervention for individual with scoliosis. Methods: Studies were selected through a search of computerized databases of the literature (KERIS, 2000-2010) using "early detection", "conservative treatment", "exercise", "physical therapy", "manipulation", "chiropractic", "therapy", "taping" and "orthosis" as keywords. Selected articles were classified by research design and statistical methods. Results: Application of the search strategy to the KERIS databases resulted in 132 articles. Based on titles and abstracts, 17 studies were selected, excluding articles of overlapping study, surgery, pharmacologic therapy and no correcting aim under conservative treatment. Among the 17 selected studies, the majorityof study design consisted of one group pretest-posttest design and additionally most of these studies were paired (or independent) t-test. The most frequently used intervention was exercise therapy. Conclusion: All articles showed that interventions were effective. Thus, early detection of scoliosis may be connected participation of early conservative treatment. It is important to reduce prevalence of scoliosis in adolescents using regular evaluation as an effective measure.

• Journal of Korean Medicine for Obesity Research
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• v.19 no.1
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• pp.56-67
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• 2019

Objectives: The purpose of this study is to review clinical studies of herb medicine and acupuncture treatment on obesity in menopausal women. Methods: Key words "Obesity", "Menopause", "Herb medicine", "Acupuncture", "Moxibustion", "Catgut embedding" were searched on 9 database systems (PubMed Central, Cochrane Controlled Register of Trials, Embase, China Academic Journals, Korean Traditional Knowledge Portal, Oriental Medicine Advanced Searching Integrated System, Korean Studies Information Service System, National Digital Science Library, DBpia) on April 30th 2019. Results: 1 case report and 17 clinical trials were collected in accordance with the selection and exclusion criteria. Among the 17 trials, 6 were randomized controlled trials, 1 was controlled clinical trial, and 10 were single-arm trials. The types of intervention were herb medicine, electroacupuncture, acupuncture, auricular acupuncture, warm needle acupuncture, moxibustion, laser acupuncture, and catgut embedding. The study design, study results and method of intervention were analyzed. Conclusions: 1 case report described the effectiveness of pharmacopuncture, 4 trials described the effectiveness of herbal medicine, 2 of electroacupuncture, 1 of laser acupuncture, and 2 of catgut embedding. Among the 17 trials, 2 studies showed that herbal medicine treatment was more effective than no treatment or selective serotonin reuptake inhibitors, and 1 study showed that electroacupuncture was more effective than hormone therapy. All of 18 selected studies reported the effectiveness of weight reduction and abdominal obesity reduction after the traditional Korean medicine treatment for obesity in menopausal women.

• Clinical and Experimental Pediatrics
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• v.62 no.8
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• pp.312-316
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• 2019

Purpose: The major side effects of treatment with oxcarbazepine (OXC) are skin rash and hyponatremia. Hematologic side effects are reported rarely. The aim of this study was to investigate the rate and types of the hematologic side effects of OXC. Methods: The medical records of 184 patients diagnosed with epilepsy or movement disorder and on OXC monotherapy, at the Department of Pediatrics of Inje University Sanggye Paik Hospital from July 2001 to July 2018, were retrospectively reviewed. Results: Of the 184 patients, 10 (5.4%) developed leukopenia in addition to pancytopenia and 2 (1.0%) developed pancytopenia. Leukopenia developed in 11 days to 14 years after OXC administration and was more frequent in males than in females (male vs. female, 9 vs. 1; Fisher exact test, P<0.05). Of the eight patients with leukopenia alone, 7 continued OXC treatment; 6 improved without intervention; 1 was lost to follow-up; and 1 received a reduced OXC dose, who improved after intervention. Pancytopenia developed within 2 months of initiation of OXC treatment. Both patients initially continued OXC. One improved within 1 month and continued treatment with OXC, but the other showed progression of the side effect, leading to the discontinuation of OXC and subsequent improvement within 1 month. There were no significant differences in the ages of the patients, OXC dose, and duration of OXC treatment between patients with and without these side effects of OXC (P>0.05, t-test). Conclusion: OXC-induced leukopenia is not rare and may result in pancytopenia. Patients being treated with OXC should be regularly monitored for abnormal complete blood count profiles.

• Journal of Acupuncture Research
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• v.26 no.5
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• pp.137-149
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• 2009

Objectives : This study was designed to analyze whether General Coordinative Manipulation(GCM) Intervention could have effects on the balanced restoration of asymmetrical posture. Methods : Sixty eight(68) healthy volunteers(1st hypothesis: 46, 2nd hypothesis 22) participated in two GCM interventions, which have been performed 2 times a week for 3 weeks. The Global Postural System(GPS) Unit was used to measure the posture, and measurements were performed before and after the application of each intervention group. A paired t-test and wilcoxon test were used to determine the statistical significance. Results : The outcome of examining the hypothesis is as follows: 1. The 1st hypothesis: It has been proved that GCM Intervention, which coordinates the flexion type of upper extremity and the extension type of lower extremity, excluding self-care, shows the efficiency in treatment on more than two aspects of 3 parts: anterior, posterior and lateral postures, and the effects on more than 3 of 4 body types. 2. The 2nd hypothesis: It has been proved that GCM Intervention, which coordinates the flexion type of lower extremity and the extension type of upper extremity, excluding self-care, shows the treatment in efficiency on more than two aspects of 3 parts: anterior, posterior and lateral postures, and the effects on more than 2 of 3 body types. Conclusions : GCM intervention programs on the two hypothesis groups have an affect on the balanced restoration of the postural control system.

• The Journal of the Korean dental association
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• v.40 no.11 s.402
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• pp.860-868
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• 2002