• Title/Summary/Keyword: internal circulation

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Study of Insam-Buja-Tang (IBT) on MRL/MpJ-Faslpr lupus-prone mice (루푸스 동물 모델에서 인삼부자탕(人蔘附子湯)이 미치는 영향)

  • Kim, Kyoung-Shin;Moon, Sung-Sikm;Kim, Byoung-Soo;Kang, Jung-Soo
    • Journal of Haehwa Medicine
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    • v.20 no.1
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    • pp.11-23
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    • 2011
  • Systemic Lupus Erythematosus(SLE) is an autoimmune disease invading the skin, joint, kidney, intestinal membrane, neurosystem and other organs. SLE is an autoimmune disease characterized by immune dysregulation resulting in the production of antinuclear antibodies(ANA), generation of circulating immune complexes, and activation of the complement system. In Korean medicine, lupus can be classified as acute arthritis, reddish butterfly erythema, asthenic disease, edema and so on. The cause and procedure of the diseases are flourishing noxious heat, excessive fire due to deficiency of yin, blood stasis due to stagnation of qi, internal movement of the liver-wind, congenital deficiency, exhausted vital-qi, which are treated by clearing away heat and cooling the blood, nourshing yin and extinguishing fire, treating flatulence and activating blood circulation, nourishing the blood to expel wind, invigorating the liver and kidney, invigorating qi and replenishing the blood. To experimentally examine the influence of Insam-Buja-Tang (Ginseng & Aconiti Extract, IBT) on the outbreak and development of lupus, lupus induce MRL/MpJ-Faslpr lupus-prone mice model was used. As IBT was orally administrated to a lupus model mouse, various tests such as the weight, urine protein, renal function, Lymph cell test of the spleen, Cytokine expression, histopathological analysis of kideny were performed to see the influence on the kidney and whether it work effectively on the immune function. The main purpose of this study is to evaluate the effect of IBT on MRL/MpJ-Faslpr lupus-prone mice model. The effect of IBT on MRL/MpJ-Faslpr lupus-prone mice that can have autoimmune disease similar to SLE in human was evaluated after IBT per oral in the present study.

A Study on the Later Architectural Intentions of Le Corbusier in Designing the Governor's Place (르 꼬르뷔제의 후기(後期) 건축적(建築的) 지향(志向)에 관한 연구 -주지사 관저 계획을 중심으로-)

  • Lee, Young
    • Journal of architectural history
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    • v.8 no.4 s.21
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    • pp.95-112
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    • 1999
  • This Study starts from a recognition that the architecture is based on the process demanded by substantial needs as well as pure theoretical logic system. So this study aims at proposing another point of view differentiating process and principle of architecture from pure theoretical logic system in the creative process of the Governor's Palace by analyzing drawings in chronological order. Even though the Governor's Palace had not been built because of discord between authorities of India and Le Corbusier, it is undoubtedly one of the best proposals which contains very concepts and ideas of later Le Corbusier's architectural intentions. In the first design stage, overall conception of the building was carried out in the sketches and drawings till Jan, 1954 and in the second stage, the elaboration of the project was pursued till Mar. 1995. The scheme tends to begin too large and general in character, becoming tighter and more complex under pressure from the client and adjustments required by the design process itself. For example, scale reduction, division and development of internal circulation system and applying his early 'Five Points'. So new solutions are searched by oscillating between compromise modifications and radically different solutions in contracting the first ideas. From all these, it is concluded that the early doctrine (Five Points) are adjusted and extended towards another stage by the use of restricted pilotis, the concept of fenetre en longueur transformed into a sub stricture of facade, sustained concept of le plan libre, les toits jardins extended towards concept of the urban area. And these formal intentions of the Governor's Place has been carried through other contemporary projects like Mill Owner's Association in 1954 and Villa Shodan in 1952.

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Refering to Sundry Records about Cause, Process and Treatment of Jungkijeung(Zhongqizheng) (중기(中氣)의 병인병기(病因病機) 및 치료(治療)에 관한 문헌고찰(文獻考察))

  • Hong, Suk;Lee, Dong-Won
    • Journal of Oriental Neuropsychiatry
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    • v.11 no.1
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    • pp.115-130
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    • 2000
  • Object: Show the treatment about Jungkijeung (Zhongqizheng) by distinguishing Apoplexy(Zhongfeng), yujungfung(Leizhongfeng), gualjung(Juezheng), and observation of cause, process, quality. Method: Researched definition, cause, process, treatment and herb med through chinese & korean medical publication refered to Jungkijeung(Zhongqizheng) Result: 1. Jungkijeung(Zhongqizheng) is simmilar to Apoplexy(Zhongfeng) that spiritual shock occurred to syncope, dysarthria, trismus, quadriplegia. But the symptom of Jungkijeung(Zhongqizheng) is coldness, no-sputum, sink-pluse; that of Apoplexy(Zhongfeng) is warmness, much secretion, float-pulse. 2. Jungkijeung(Zhongqizheng) is mainly caused by the serious anger and the reverse movement of spints by the seven emotional factor. The process of Jungkijeung(Zhongqizheng) are "Fire and Fever(huore)" "Weatness and sputum(shitan)", and most importantly "Weakness of vital-qi(qixi)" 3. The treatment of Jungkijeung(Zhongqizheng) is adjustment and circulation of jiao. In early stage, don't use of Apoplexial- Med. 4. As following herb-med are used for Jungkijeung (Zhongqizheng). Sohaphang-won(Suhexiangyan) is 18 times; Palmisungi-san(Baweishunqisan) is 13 times; Kang-tang(Jiangtang) is 8 times: Mokhyangsungi san(Muxiangshunqisan) is 6 times. 5. Atractylodes macrocephala KOIDZ(Baishu) is used for 40 times most frequently, Saussurea lappa CLARKE (Muxiang), Cyperus rotundus L (Xiangfuzi), Citrus unshiu MARCOR(Chenpi), Glycyrrhiza uralensis FISCH (Gancao), poria cocos WOLF (Furing), Panax ginseng NESS (Renshen) etc are orderly used. 6. Acupoints same as GV20(Baihui), LI4(Hegu), Liv2(Xingjian), 12 Junghyul(Jingxue) is used for acupunture. And CV8(Shenque), CV4(Guanyan) is used for moxibustion. Conclusion: As Jungkijeung(Zhangqizheng) is differed from Apoplexy(Zhongfeng), yujungfung(Leizhongfeng), gualjung(Juezheng), we must also cure Jungkijeung (Zhongqizheng) to the other disease. It is need to distinguishment Jungkijeung(Zhongqizheng) from neurotic, psychotic disease, though similar to conversation neurosis.

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A Study on Development of Food Delivery Platform based on O2O -Focusing on Domestic and Overseas Cases (O2O 기반 식품 배달 플랫폼 발전 방안 연구 -국내외 사례를 중심으로-)

  • Park, Seojin;Kim, Seung-In
    • Journal of the Korea Convergence Society
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    • v.9 no.9
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    • pp.159-165
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    • 2018
  • In this research, the researcher is seeking how to develop growing O2O food delivery platform service. The food delivery platform is newly creating the profit system which wasn't exist before by adding up IT and new technologies, and young generations who are used to mobile environment have became main consumers. For the methodology of research, internal and external delivery platform cases research is used to suggest the development idea. Food delivery platform market is showing an active development like business expansion by M&A of IT, distribution, manufacturing, circulation and it still has to attract the constant use of consumer through zero commission, discount events. Further research is required for various delivery platform channel and consumer's value of overall experience, above hereafter food delivery platform based on this research.

Studies on the Effects of Danggieum and Ijintang on Thrombosis and Elevated Blood Viscosity (혈전증(血栓症) 및 고점도혈증(高粘度血症)에 대(對)한 당귀음(當歸飮)과 이진탕(二陳湯)의 실험적(實驗的) 연구(硏究))

  • Kim, Young-Suk
    • The Journal of Korean Medicine
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    • v.15 no.2 s.28
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    • pp.212-232
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    • 1994
  • I selected the theory of blood stasis and wetness-phlegm among the major 4 causes of Joong Poong(C.V.A.)(wind. fire. deficiency of vital energy and wetness-phlegm) and recent etiology of blood stasis. An experimental studies were done to investigate the effects of Danggieum (removing blood stasis and promoting blood circulation) and Ijintang(dissipating wetness-phlegm) on thrombosis and elevated blood viscosity. The results were as follows; 1. The number of platelets were significantly increased in only Danggieum group. 2. Related to the amount of fibrinogen. only Danggieum group revealed some increase. but both groups revealed no significance. 3. Related to the prothrombin time. Danggieum and Ijintang groups had significant decrease. but Danggieum group revealed more significance. 4. Related to the degree of concentration of FDP, only Danggieum group had significant decrease. 5. Whole blood viscosity and plasma viscosity in lower shear rates. both groups of Danggieum and Ijintang had significant decrease. 6. Related to the amount of RBC. both groups of Danggieum and Ijintang had significant decrease. 7. Related to the change of hematocrit. only Danggieum group, and the change of hemoglobin. only Ijintang group had significant decrease. 8. Related to the change of body temperature. only Ijintang group had significant raise. 9. Related to the changes of WBC. glucose, albumin, total protein and body weight. Danggieum and Ijintang groups had each increase or decrease. but no significance. According to the above results, Danggieum had more significant effect than Ijintang on the thrombosis. and Ijintang had more significant effect than Danggieum on the elevated blood viscosity. And it is considered that it might be more effective in treating Joong-Poong(C.V.A) to take medicines regarding patient's constitution and symptoms as well as the causes of Joong-Poong(C.V.A)

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Modified Suturing Techniques in Carotid Endarterectomy for Reducing the Cerebral Ischemic Time

  • Joo, Sung-Pil;Cho, Yong-Hwan;Lee, Yong-Jun;Kim, You-Sub;Kim, Tae-Sun
    • Journal of Korean Neurosurgical Society
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    • v.63 no.6
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    • pp.834-840
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    • 2020
  • Objective : Carotid endarterectomy (CEA) is an effective surgical procedure for treating symptomatic or asymptomatic patients with carotid stenosis. Many neurosurgeons use a shunt to reduce perioperative ischemic complications. However, the use of shunting is still controversial, and the shunt procedure can cause several complications. In our institution, we used two types of modified arteriotomy suture techniques instead of using a shunt. Methods : In technique 1, to prevent ischemic complications, we sutured a third of the arteriotomy site from both ends after removing the plaque. Afterward, the unsutured middle third was isolated from the arterial lumen by placing a curved Satinsky clamp. And then, we opened all the clamped carotid arteries before finishing the suture. In technique 2, we sutured the arteriotomy site at the common carotid artery (CCA). We then placed a curved Satinsky clamp crossing from the sutured site to the carotid bifurcation, isolating the unsutured site at the internal carotid artery (ICA). After placing the Satinsky clamp, the CCA and external carotid artery (ECA) were opened to allow blood flow from CCA to ECA. By opening the ECA, ECA collateral flow via ECA-ICA anastomoses could help to reduce cerebral ischemia. Results : The modified suture methods can reduce the cerebral ischemia directly (technique 1) or via using collaterals (technique 2). The modified arteriotomy suture techniques are simple, safe, and applicable to almost all cases of CEA. Conclusion : Two modified arteriotomy suture techniques could reduce perioperative ischemic complications by reducing the cerebral ischemic time.

The Clinical Study of Parkinson‘s disease And Parkinson’s syndrome improved with Chuna-Treatment (파킨슨병, 파킨슨 의증 환자 2례에서 추나치료에 대한 증례보고)

  • Kim, Chang-Yeon;Min, Ji-Yeon;Choi, Young-Gui;Koh, Young-Tak;Jung, Young-Hoon;Cho, In-Hee;Kim, Tae-Soo
    • The Journal of Korea CHUNA Manual Medicine
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    • v.6 no.1
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    • pp.127-135
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    • 2005
  • Object : To discuss the Use of Chuna treatment in managing two patients with Parkinson's disease and/or Parkinson' syndrome Methods : This clinical study was carried out of 2 cases with confirmed by certified neurologist Parkinson's disease and/or Parkinson' syndrome. One case had been admitted from 2004.09.16 to 2004.09.24 and treated from 2004.09.26 to 2004.10.15 and the other case had been admitted from 2004.10.21 to 2004.11.06 and treated from 2004.11.08 to 2004.11.15 in the department of acupuncture and moxibustion of Ha-na oriental medical center. Results : There was significant improvement in condition of the two patients treated by Chuna treatment(upper cervical to promote CSF circulation) on Parkinson's disease or Parkinson' syndrome. Conclusion: In the case, we treated two patients of Parkinson's disease and/or Parkinson' syndrome. Chuna treatment efficiently relieved the symptoms including tremor and bradykinesia.

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Experimental Investigation of an Cross-Flow Air-Cooled Plate Heat Exchanger with Single-Wave and Double-Wave Plates (단일굴곡 및 이중굴곡 판 형상을 갖는 직교류 공랭식 판형열교환기의 전열특성에 대한 실험적 연구)

  • Kim, Min-Sung;Paik, Young-Jin;Lee, Jae-Hoon;Park, Seong-Ryong;Ra, Ho-Sang;Jeong, Jae-Hoon;Lim, Hyug
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.21 no.6
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    • pp.347-354
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    • 2009
  • Experimental study on a cross-flow air-cooled plate heat exchanger (PHE) was performed. Two types of PHEs were manufactured either with single-wave plates or with double-wave plates in parallel. Cooling air flows through the PHEs in a crosswise direction against internal hot water. The heat exchanger aims to substitute open-loop cooling towers with closed-loop water circulation, which guarantees cleanliness and compactness. In this study, prototype single-wave and double-wave PHEs were designed and tested in a laboratory scale experiments. From the tests, the double-wave PHE shows approximately 50% enhanced heat transfer performance compared to the single-wave PHE. However, the double-wave PHE costs 30% additional pressure drop. For the commercialization, a wide channel design for air flow would be essential for performance and reliability.

Review on the Capillary Destruction of Telangiectasia, and the Clinical Applications Using Modern Methods in Korean Medicine (모세혈관확장 치료에 있어서 혈락자파법에 대한 고찰 및 한의임상에서 현대적 활용 전망)

  • Jang, Insoo;Song, Beomyong;Lee, Eunhee;Lee, Donghyo;Seo, Hyungsik;Koo, Sungtae
    • Korean Journal of Acupuncture
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    • v.31 no.1
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    • pp.1-4
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    • 2014
  • Objectives : The capillary destruction has frequently been used to treat telangiectasia in Korean Medicine. The objective of this study was to review of related literature concerning the capillary destruction as treatment for telangiectasia, and to discuss the clinical application of medical devices in accordance with the principles of Korean Medicine. Methods and Results : An extensive traditional literature including Huangdi Neijing were reviewed for identification of relevant evidence for treating telangiectasia. The telangiectasia is simply defined as a dilated, superficial blood vessel. It is called as the tertiary collateral vessel, superficial collateral vessel or Hyulrak(small superficial collateral vessel). The telangiectasia could be due to disturbances in the circulation of qi and blood. According to Huangdi Neijing, one of the oldest traditional literature published in 4th century B.C. through the first century A.D., it is needed to get rid of the vessel by the capillary destruction for treating telangiectasia using lance needle, shear needle, stiletto needle or moxibustion. Several studies have examined that intense pulsed light or laser as new therapeutic tools could have an sufficiently impact on aspects of improving the effectiveness of the capillary destruction. Conclusions : The capillary destruction for the treatment of telangiectasia has been used since two thousand years ago. We suggested that medical devices, such as intense pulsed light or laser, should be used to treat telangiectasia as a safe and convenient intervention in clinical practice of Korean Medicine.

Vacuum Carburizing System for Powdered Metal Parts & Components

  • Kowakewski, Janusz;Kucharski, Karol
    • Proceedings of the Korean Powder Metallurgy Institute Conference
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    • 2006.09b
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    • pp.1018-1021
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    • 2006
  • Powdered metal parts and components may be carburized successfully in a vacuum furnace by combining carburizing technology $VacCarb^{TM}$ with a hi-tech control system. This approach is different from traditional carburizing methods, because vacuum carburizing is a non-equilibrium process. It is not possible to set the carbon potential as in a traditional carburizing atmosphere and control its composition in order to obtain a desired carburized case. This paper presents test results that demonstrate that vacuum carburizing system $VacCarb^{TM}$ carburized P.M. materials faster than traditional steel with acceptable results. In the experiments conducted, PM samples with the lowest density and open porosity showed a dramatic increase in the surface carbon content up to 2.5%C and a 3 times deeper case. Currently the boost-diffusion technique is applied to control the surface carbon content and distribution in the case. In the first boost step, the flow of the carburizing gas has to be sufficient to saturate the austenite, while avoiding soot deposition and formation of massive carbides. To accomplish this goal, the proper gas flow rate has to be calculated. In the case of P.M. parts, more carbon can be absorbed by the part's surface because of the additional internal surface area created by pores present in the carburized case. This amount will depend on the density of the part, the densification grade of the surface layer and the stage of the surface. "as machined" or "as sintered". It is believed that enhanced gas diffusion after initial evacuation of the P.M. parts leads to faster carburization from within the pores, especially when pores are open . surface "as sintered" and interconnected . low density. A serious problem with vacuum carburizing is delivery of the carbon in a uniform manner to the work pieces. This led to the development of the different methods of carburizing gas circulation such as the pulse/pump method or the pulse/pause technique applied in SECO/WARWICK's $VacCarb^{TM}$ Technology. In both cases, each pressure change may deliver fresh carburizing atmosphere into the pores and leads to faster carburization from within the pores. Since today's control of vacuum carburizing is based largely on empirical results, presented experiments may lead to better understanding and improved control of the process.

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