• Allergy, Asthma & Respiratory Disease
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• 제6권6호
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• pp.310-314
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• 2018

Purpose: Conventional serum IgE assay was costly, required the skills of expert, and relied heavily on expensive equipment. Quantitative measurement of total IgE using Point of Care Test (POCT) device can be the solution for these limitations. This study evaluated and validated the reproducibility of ImmuneCheck IgE. Methods: This study included 120 patients of allergic diseases such as allergic rhinitis, asthma, drug allergy, food allergy, atopic dermatitis, or anaphylaxis. The reliability of POCT ImmuneCheck IgE was evaluated by comparing results from the naked eye and from the Q-Reader. Intratest reproducibility and intertest correlation were analyzed using intraclass correlation coefficient (ICC). Results: Of the 120 enrolled patients, 51 were males and 69 were females. The ages ranged from 19 to 84 years, with an average age of 51.5 years. The concentration of serum total IgE measured by Phadia ImmunoCAP IgE ranged from 5.95 to 5,000 IU/mL. ICC for Intratest reproducibility of ImmuneCheck IgE by naked eye and by Q-Reader were 0.991 (P< 0.001) and 0.989 (P< 0.001), respectively. In addition, intertest correlation between ImmuneCheck IgE and Phadia ImmunoCAP IgE results of naked eye and Q-Reader were 0.968 (P< 0.001) and 0.948 (P< 0.001), respectively. Conclusion: The ImmuneCheck IgE was reproducible and highly correlated with conventional Phadia ImmunoCAP IgE assay. This result suggests that ImmuneCheck IgE can be a useful tool for rapid and precise detection of total IgE.

• 대기
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• 제22권3호
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• pp.299-307
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• 2012

This study is aimed to validate errors for detected suspicious temperature data using various quality control procedures for 61 weather stations in the Republic of Korea. The quality control algorithms for temperature data consist of four main procedures (high-low extreme check, internal consistency check, temporal outlier check, and spatial outlier check). Errors of detected suspicious temperature data are judged by examining temperature data of nearby stations, surface weather charts, hourly temperature data, daily precipitation, and daily maximum wind direction. The number of detected errors in internal consistency check and spatial outlier check showed 4 days (3 stations) and 7 days (5 stations), respectively. Effective and objective methods for validation errors through this study will help to reduce manpower and time for conduct of quality management for temperature data.

• 한국군사과학기술학회지
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• 제22권4호
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• pp.501-508
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• 2019

In this paper, a study on a wireless check-up method of test equipment for captive flight test(CFT) was conducted. For CFT, test equipment is mounted on a POD, and check-up is carried on the test equipment's. For check-up the POD wirelessly, battery, power distribution unit, wireless communication devices were designed within the POD, and a check-up device is designed outside of the POD. Once the external check-up device sends a 'start signal' to the POD, it performs the overall check-up procedures and transmits the 'end signal' to the external check-up device. Detailed check-up results are stored in an internal storage device, and are possible to read from external check-up device if necessary, thereby improving the reliability of the wireless check-up. By implementing and applying these wireless check-up system, the reliability of the check-up was enhanced by dynamical and movable check-up, and safety is guaranteed as the check-up was carried without access to the aircraft.

• Journal of Neurogastroenterology and Motility
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• 제24권4호
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• pp.603-613
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• 2018

Background/Aims Functional dyspepsia (FD) is one of the most common gastrointestinal disorders, and FD imposes social and economic burden worldwide. The aim of this study is to identify the prevalence and risk factors of FD in health check-up population in tertiary centers in Korea. Methods A nationwide multicenter prospective study was performed at 9 tertiary healthcare centers in Korea between September 2016 and June 2017. A total of 2525 subjects were investigated based on endoscopic findings and questionnaires with the Rome III criteria, and Helicobacter pylori serology (IgG). Results A total of 1714 subjects without organic disease were enrolled. The mean (${\pm}SD$) age was 51.5 (${\pm}12.7$) years, and 917 patients (53.5%) were female. The proportion of H. pylori seropositivity was 51.0% (874/1714). The prevalence of FD was 10.3% (176/1714), and the subtypes of postprandial distress syndrome alone, epigastric pain syndrome alone, and postprandial distress syndromeepigastric pain syndrome overlap were 4.8%, 3.0%, and 2.5%, respectively. Multivariate analysis showed that female gender (OR, 1.58; 95% CI, 1.14-2.21) and education below college level (OR, 1.45; 95% CI, 1.01-2.07) were related to FD. Multivariate analysis based on age 60 showed female gender as a significant (OR, 2.90; 95% CI, 1.06-7.94) factor in the group ${\geq}60$ years. Conclusions The prevalence of FD was 10.3% in the health check-up population in Korea. Female sex and education below college level were risk factors for FD. Female sex is a risk factor for FD in old age, underscoring the need for close attention in this age group.

• 대한한방내과학회지
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• 제26권1호
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• pp.60-73
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• 2005

Objectives : The aim of this study was to evaluate the effects of Loranthus parasiticus Merr. on cell cycle and expression of related genes in HepG2 cells. Methods : The MTT assay, cell counting assay, $[^3H]-Thymidine$ incorporation assay, flow cytometric analysis, quantitative RT-PCR and western blot assay were studied. Results : In the water extract of Loranthus parasiticus Merr., inhibition of cell proliferation and DNA synthesis in HepG2 cells was seen. These inhibitory effects were due to inhibition of G l-S transition in cell cycle. After treatment with the extract, expression of cyclin D1(G1 check point related gene) was inhibited particularly in dose-dependent and time-dependent manners. Conclusion : These results suggest that the inhibition of cell cycle progression by Loranthus parasiticus Merr. in HepG2 cell is due to suppression of cyclin D1(G1 check point related gene) mRNA expression and protein synthesis.

• 동력기계공학회지
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• 제11권1호
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• pp.39-44
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• 2007

The purpose of this study is to verify availability of the acoustic emission in-situ monitoring method to the internal leak and operating conditions of the major valves at nuclear power plants. In this study, acoustic emission tests are performed when the pressurized temperature water and steam flowed through glove valve(main steam dump valve) and check valve(main steam outlet pump check valve) on the normal size of 12 and 18". The valve internal leak monitoring system for practical field was designed. The acoustic emission method was applied to the valves at the site, and the background noise was measured for the abnormal plant condition. To improve the reliability, a judgment of leak on the system was used various factors which are AE parameters, trend analysis, frequency analysis, voltage analysis and amplitude analysis of acoustic signal emitted from the valve operating condition internal leak.

• 혜화의학회지
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• 제9권1호
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• pp.409-421
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• 2000

According to The Comparative study on the IgA Nephropathy and hematuria, the results were as follows. 1. IgA nephropathy is included in category of the hematuria the part in deficiency of liver-kidney and damp-heat in oriental medicine. 2. The symptoms of hematuia is changes in color of urine-bloody, dark brown, or rusty colored-without pain in oriental medicine. 3. It is occured IgA nephropathy due to vacuity exhaustion, fidgetiness, internal damage, imfection. 4. For the medical prescriptions due to IgA nephropathy are used Sogyeeumja, $Dayebunch\check{o}ngeum$(大分淸飮), Dangguieum(當歸飮), $Ch\check{o}ngjangtang$(淸腸湯), Silyungtang(柴岺湯), Kamisagunjatang(加味四君子湯) as hematuria of symtom of IgA nephropathy.

• 대한한방내과학회지
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• 제33권2호
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• pp.180-187
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• 2012

Objectives : The aim of this study was to investigate weight gain effects of the Sungjangjeungbo-tang (Ch$\acute{e}$ngzh$\check{a}$ngz$\bar{e}$ngb$\check{u}$-tang) on thin Korean preschool children. Methods : Sungjangjeungbo-tang is composed of 9 herbs for treating indigestion. We analyzed 119 preschool children who visited Kim Kijoon Oriental Clinic BOM from Jan. 1, 2006 to Aug. 31, 2011 with three criteria: 1) 2~5yrs of age and BMI < 50th percentile on the baseline visit; 2) the child had taken the Sungjangjeungbo-tang for 1~3 month(s); and 3) the clinic had records of both height and weight on the baseline and at least once over 1~3 month(s). Results : Sungjangjeungbo-tang significantly improved BMI percentile in all groups. The changes in BMI percentile variations were larger in the 3 months group than in other groups, but not significantly. Gender, age and BMI on the baseline had no significant effects on the effectiveness of Sungjangjeungbo-tang. Conclusions : Sungjangjeungbo-tang positively affected on weight gain in thin Korean preschool children within 1~3 month(s) of treatment. However, additional studies on functional dyspepsia or the change of energy intake were needed to know the factors related to weight gains.

• 동력기계공학회지
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• 제20권1호
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• pp.5-10
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• 2016

Swing check valve is opened when the flow direction is forward, when the flow is reversed, the valve is automatically closed by back pressure. In this study, the internal flow field analysis of the valve was conducted by Fluent. The working fluid used in the study, using liquefied methane $-165^{\circ}C$ (CH4) and velocity field, pressure field, pressure drop coefficient were simulated by varying separately the opening divergence into four intervals from 0 to 100%. The approximate research result are as follow : When the opening divergence is smaller, it appears high pressure on the upstream side, this value is relaxed when the opening divergence is large. Flow rate coefficient of the valve shows a larger value as the degree of opening becomes larger, confirming that the check valve used in the study is in the effective flow rate counting range.

• Journal of the Korean Wood Science and Technology
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• 제25권4호
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• pp.99-107
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• 1997

This study was executed to test the possibility of replacement for domestic Japanese larch(Larix leptolepis) for hardwoods and to acquire the information about the effects of drying temperature on internal temperature, moisture content and drying defects. In high-temperature drying, internal temperature increased rapidly to boiling point, immediately after that point the internal temperature rising rate was reduced. In the case of drying at temperature of $125^{\circ}C$, internal temperature could reach at boiling point in a very short time. Moisture content in high-temperature drying showed constant drying rate period and first period of falling rate drying together in 4 hours since experiment begun. There was no strong correlation between initial moisture content and final moisture content. Average drying rate at $115^{\circ}C$, $120^{\circ}C$ and $125^{\circ}C$ was 1.42%/hr, 1.88%/hr and 2.02%/hr, respectively; the case of drying temperature of $125^{\circ}C$ showed most rapid drying rate. Drying rate of $125^{\circ}C$ was so rapid that it showed more severe shrinkage, bow, collapse, end check, and internal check development than in other drying conditions. The result of this study showed the strong possibility of high-temperature drying for Japanese larch, and to dry Japanese larch optimally, dry bulb temperature should not exceed $120^{\circ}C$.