• Journal of Veterinary Clinics
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• v.25 no.2
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• pp.73-78
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• 2008

Ketamine is a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist and a short-acting general anaesthetic agent for human and veterinary use. We previously reported that treatment with ketamine impairs oxidative burst activity of canine peripheral blood leukocytes. In this study, the effect of ketamine on phagocytic capacity of canine peripheral blood leukocytes was examined in vitro. Phagocytic capacity was analyzed by using a flow cytometry. Ketamine directly decreased the phagocytic capacity of peripheral blood polymorphonuclear cells (PMN) and monocytes but not total peripheral blood mononuclear cells (PBMC). In addition, the phagocytic capacity of PMN and monocytes was inhibited by the ketamine-treated PBMC but not PMN culture supernatant. These results suggest that ketamine has a direct inhibitory effect on the phagocytic capacity of canine peripheral blood phagocytes and involves the production of soluble factor(s) from canine PBMC, which may suppress the phagocytic capacity.

• Tuberculosis and Respiratory Diseases
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• v.81 no.1
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• pp.42-48
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• 2018

Background: The diffusing capacity of the lung is influenced by multiple factors such as age, sex, height, weight, ethnicity and smoking status. Although a prediction equation for the diffusing capacity of Korea was proposed in the mid-1980s, this equation is not used currently. The aim of this study was to develop a new prediction equation for the diffusing capacity for Koreans. Methods: Using the data of the Korean National Health and Nutrition Examination Survey, a total of 140 nonsmokers with normal chest X-rays were enrolled in this study. Results: Using linear regression analysis, a new predicting equation for diffusing capacity was developed. For men, the following new equations were developed: carbon monoxide diffusing capacity (DLco)=-10.4433-0.1434${\times}$age (year)+0.2482${\times}$heights (cm); DLco/alveolar volume (VA)=6.01507-0.02374${\times}$age (year)-0.00233${\times}$heights (cm). For women the prediction equations were described as followed: DLco=-12.8895-0.0532${\times}$age (year)+0.2145${\times}$heights (cm) and DLco/VA=7.69516-0.02219${\times}$age (year)-0.01377${\times}$heights (cm). All equations were internally validated by k-fold cross validation method. Conclusion: In this study, we developed new prediction equations for the diffusing capacity of the lungs of Koreans. A further study is needed to validate the new predicting equation for diffusing capacity.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.8
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• pp.362-370
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• 2019

The internal pressure capacity of a modular containment structure requires analysis to prevent the release of radioactive material in the case of an accident. To analyze the capacity, FEM models were prepared while considering the tendon arrangements and the contact surfaces between precast concrete modules, and then static analyses were carried out. The changing characteristics in the displacement and stress under step-wise loading were analyzed, along with the effects of selected parameters. For comparison, the capacity of a monolithic containment structure was also analyzed. Parametric analyses were done to suggest ranges of parameters such as the tendon force, tendon spacing, tendon location in concrete thickness direction, friction coefficient, and concrete thickness. The tendon force and frictional force provide a combined effect between contact surfaces of modules. The same level of internal pressure capacity can be secured even in the modular containment structure as in the monolithic containment structure by increasing the tendon force with additional tendons.

• Nuclear Engineering and Technology
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• v.55 no.10
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• pp.3677-3691
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• 2023

Since containment building is the major shielding structure to ensure safety of nuclear power plant, the structural behavior and ultimate pressure capacity of containments must be studied in depth. This paper addresses ambiguous issue of determining free-field position for liner failure by suggesting an expanded free-field region and comparing internal pressure capacities obtained by test data, conservative assumption and suggested free-field region. For this purpose, a practical approach to determine the free-field position for the evaluation of liner tearing is carried out. The maximum principal strain histories versus internal pressure capacities among different free-field positions at various azimuths and elevations are compared with those at the equipment hatch as a conservative assumption. The comparison shows that there are considerable differences in the internal pressure capacity at liner failure within the expanded free-field region compared to the vicinity of the equipment hatch. Additionally, this study proposes an approximate correlation with conservative factors by considering the expanded free-field ranges and material characteristics to determine realistic failure criteria for liner. The applicability of the proposed correlation is demonstrated by comparing the internal pressure capacities of full-scale containment buildings following liner failure criteria according to RG 1.216 and an approximate correlation.

• Geomechanics and Engineering
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• v.35 no.1
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• pp.41-54
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• 2023

The use of a skirt, a vertical projection attached to the footing, is a recently developed method to increase the bearing capacity of soils and reduce foundation settlements. Most of the studies were focused on vertical skirted circular footings resting on clay while neglecting the rigidity and inclination of skirts. This study employs finite element limit analysis to investigate the bearing capacity enhancement of flexible and rigid inclined skirts in cohesionless soils. The results indicate that the bearing capacity initially improves with an increase in the skirt inclination but subsequently decreases for both flexible and rigid skirts. However, the rigid skirt exhibits more apparent optimum skirt inclination and bearing capacity enhancement than the flexible one, owing to differences in their failure mechanisms. Furthermore, the bearing capacity of the inclined skirted foundation increases with the skirt length, footing depth, and internal friction angle of the soil. In the case of rigid skirts, the bearing capacity increases linearly with skirt length, while for flexible skirts, it reaches a stable value at a certain skirt length. The efficiency of the flexible footing reduces as the footing depth and soil internal friction angle increase. Conversely, the efficiency of the rigid skirt decreases only with an increase in the depth of the footing. The paper also presents a detailed analysis of various failure patterns, highlighting the behaviour of inclined skirted footings. Additionally, nonlinear regression equations are provided to quantify and predict the bearing capacity enhancement with the inclined skirts.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.1
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• pp.69-73
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• 2013

Internal heat exchanger (IHX) apparatus using the temperature difference between high and low pressure lines in vehicle air conditioning system is a good method to enhance the cooling performance. In this study, we designed various double-pipe internal heat exchangers which have inner fins between the internal pipe and external pipe. We also measured the performance characteristic (pressure drop, cooling capacity, compressor work and coefficient of performance (COP)) of the modified internal heat exchangers that had the change of the fin height and the inside shape of the internal pipe. This experimental results indicated that the liner and serration type internal heat exchanger was the best cooling performance. In addition, the air conditioning system with the liner and serration type internal heat exchanger showed the improved performances of about 6.4% and 9.2%, respectively, for the cooling capacity and COP.

• Proceedings of the Korean Geotechical Society Conference
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• 1999.03a
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• pp.225-232
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• 1999

Construction case of PRD (Percussion Rotary Drill) pipe pile and matters to be attended in construction of PRD pile were reviewed. The compressive and uplifting static pile load tests for PRD piles were performed and, also, analysis by Pile Driving Analyzer was done. Based on these results, bearing components in each resisting part (that is: steel toe, external skin, and internal skin) were measured separately. The measured resisting force was compared to the value calculated by the estimated formula. The pile capacity was mobilized in steel toe area and the external skin friction and the internal friction were not produced. Thus, it could be considered that toe of PRD pile should be supported in hard bearing stratum (for example, the fresh soft rock).

• Journal of the Korean Professional Engineers Association
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• v.14 no.4
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• pp.15-25
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• 1981

Electrical behaviors of the divalent silver oxide-zinc cell were analyzed for imporving capacity and keeping electrodes from passivation or sharp increases of cell internal resistance in the course of discharge. One of primary factors in relation to lowering performance can be depicted by cell internal resistance increase being created by various routes, first by insufficiency and/or the carbonation of the electrolyte, secondly by barrier blockage, thirdly by electrode passivation which are due to improper material use of wrong processing, and by gassing as fourth cause. The carbonation causes electrobyte to have impedance up as well as poor amalgamation, resulting in vigorous corrosion reaction of copper plated inner top, evolving hydrogen gas. Electrical characteristics of the cell was reviewed to elucidate relationships between the discharge capacity and the cell internal resistance.

• Journal of the Korean Wood Science and Technology
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• v.35 no.5
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• pp.38-45
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• 2007

Flakeboards made from ring- and drum-cut flakes of Douglas-fir, hemlock, red lauan and kapur using two kinds of resin levels were evaluated for the selected properties according to flake thickness. The pH and buffering capacity of four species were determined. Those of kapur were extremely different from the other three species. These pH and buffering capacity values result in the poor internal bond strength of kapur flakeboard. The internal bond strength was affected significantly by flake thickness, resin content and species. MOR and MOE in bending strength were maximized at medium drum-cut flake thickness. Screw holding strength was not consistent for flake thickness, but it was influenced by species. Thickness swelling and water absorption of Douglas-fir and hemlock flakeboard were minimized at medium drum-cut flake thickness.

• Proceedings of the KIPE Conference
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• 2005.07a
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• pp.170-172
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• 2005

Internal battery ohmic measurements have been a hot topic amongst battery users and battery manufacturers. As a battery deteriorates and loses its capacity, the internal resistance of the battery increases. Everyone seems to agree that measuring the internal parameters of a cell can be very useful in determining a battery's state of health. In this paper experiences show that if a cell's resistance increases by more than25% above its baseline value(known good resistance of new 100% capacity cell), the cell will no loger be able to deliver 80% or more of the rated capacity.