• Title/Summary/Keyword: intermediates

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Isolation and identification of rhodopseudomonas sp. in Korea (한국산 rhodopseudomonas sp.의 분리 및 동정)

  • 오덕철;이현순
    • Korean Journal of Microbiology
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    • v.13 no.1
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    • pp.24-30
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    • 1975
  • this work was designed to study the species belonging to Family Rhodospirillaceae in Korea. The species of Rhodopseudomonas palustris and R. gelatinosa were isolated and identified. The utilization of various substrates such as malate, succinate, citrate, pyruvate, propionate and acetate were tested with isolated KS 007 and KS o16. Though there were some differences according to nitrogen source in media it was thought that he intermediates of TCA cycle were comparatively good substrates, Also it was confirmed that isolated strains have the ability of nitrogen fixation.

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Novel Synthesis of the Natural Protoberberine Alkaloids: Oxypalmatine and Oxypseudopalmatine

  • Le, Thanh Nguyen;Cho, Won-Jea
    • Bulletin of the Korean Chemical Society
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    • v.28 no.5
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    • pp.763-766
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    • 2007
  • Oxypalmatine and oxypseudopalmatine were synthesized in three steps from the benzonitrile 11 and toluamides 12a, b. The lithiated cycloaddition reaction yielded 3-arylisoquinolinone intermediates. A subsequent internal SN2 reaction produced the corresponding 8-oxoprotoberberines, oxypalmatine and oxypseudopalmatine.

Synthesis and Mass Spectrometry of Deueteriu Labeled Tranylcypromine Hydrochloride

  • Kang, Gun-Il;Hong, Suk-Gil
    • Archives of Pharmacal Research
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    • v.8 no.2
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    • pp.77-84
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    • 1985
  • [$^{2}$H$_{2}$] Tranylcypromine hydrochloride (trans-3, 3-dideuterio-2-phenylcyclopropylamine HCL) was synthesized for application to the metabolic studies. Mass fragmentation processes for the tranylcypromine and its two synthetic intermediates .gamma-phenyl-.gamma.-butyrolactone and trans-2-phenylcyclopropanecarboxylic acid were described based upon comparisons between labeled and unlabeled compounds.

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Efficient Synthesis of 2-Substituted 2,3-Dihydro-4-quinolones as Potential Intermediates for 2-Substituted 1,2,3,4-Tetrahydro-4-quinolone Antitumor Agents

  • Choi Sun;Jung Keumn-Yeo;Ryu Jae-Sang
    • Archives of Pharmacal Research
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    • v.29 no.5
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    • pp.369-374
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    • 2006
  • An efficient method for the synthesis of optically active 2-substituted 2,3-dihydro-4-quinolones has been developed. The key features include the introduction of a chiral side chain and the construction of quinolone skeleton by Mitsunobu alkylation and hydroarylation, respectively.

An Expedient Synthesis of Oxindole Dimers by Direct Oxidative Dimerization of Oxindoles

  • Lee, Hyun Ju;Lee, Sangku;Lim, Jin Woo;Kim, Jae Nyoung
    • Bulletin of the Korean Chemical Society
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    • v.34 no.8
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    • pp.2446-2450
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    • 2013
  • Oxindole dimers have been used as intermediates in the synthesis of various cyclotryptamine alkaloids. An efficient direct synthesis of oxindole dimers has been carried out from 3-substituted oxindoles via an oxidative dimerization using manganese(III) acetate or copper acetate/silver acetate system.

Photochemistry of Conjugated Poliynes : Photochemical Generation of Silacyclopropenes from 1-Aryl-4-(pentamethyldisilanyl)buta-1,3-diynes

  • 심상철;이성택
    • Bulletin of the Korean Chemical Society
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    • v.16 no.10
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    • pp.988-990
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    • 1995
  • No fluorescence was observed from 1-aryl-4-(pentamethyldisilanyl)buta-1,3-diynes except 1-(1-naphthyl)-4-(pentamethyldisilanyl)buta-1,3-diyne. Irradiation of 1-aryl-4-(pentamethyldisilanyl)buta-1,3-diynes (1) with methanol gives photoaddition products in relatively low yields compared to arylethynyldisilanes which show dual fluorescence. Irradiation of 1 with acetone yields site specific and regioselective 1:1 photoadducts through silacyclopropene intermediates. The triplet excited state of the silacyclopropene reacts with acetone to give addition photoproducts and the triplet energy of the silacyclopropenes lies around 260-286 kJ/mol.

Theoretical Study on the Regioselectivity of Tetrazolylimines with Alkyl Grignard Reagents

  • 유성은;공영대;김수경
    • Bulletin of the Korean Chemical Society
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    • v.20 no.4
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    • pp.441-444
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    • 1999
  • The alkyl Grignard addition reaction on 1-benzyltetrazolylimine proceeds to give N-alkylated products (azophilic addition) and, in contrast, the same reaction on 2-benzyltetrazolylimine produced predominantly C-alkylated products (carbophilic addition). In this report we described theoretical explanations for this experimental finding on the basis of the frontier molecular orbitals and the electrostatic nature of the reactants and the reaction intermediates.

Enhanced Electrogenerated Chemiluminescence of Tris (2,2'-bipyridyl) Ruthenium (II)-$S_2O_8^{2-}$ System by Sodium Dodecyl Sulfate

  • Kang, Sung-Chul;Oh, Soo-Il;Kim, Kang-Jin
    • Bulletin of the Korean Chemical Society
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    • v.11 no.6
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    • pp.505-508
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    • 1990
  • The electrochemical reduction and electrogenerated chemiluminescence (ECL) of $Ru(bpy)_3^{2+}-S_2O_8^{2-}\;in\;CH_3CN-H_2O$ solution were studied in the presence of sodium dodecyl sulfate (SDS) as an anionic surfactant. SDS enhanced the ECL and the fluorescence intensities and lengthened the duration of ECL due to the solubilization of reactants and possibly to the stabilization of ECL intermediates in the SDS micellar environment.