• Journal of Ginseng Research
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• v.40 no.1
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• pp.55-61
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• 2016

Background: A number of neurological and neurodegenerative diseases share impaired cognition as a common symptom. Therefore, the development of clinically applicable therapies to enhance cognition has yielded significant interest. Previously, we have shown that activation of lysophosphatidic acid receptors (LPARs) via gintonin application potentiates synaptic transmission by the blockade of $K^+$ channels in the mature hippocampus. However, whether gintonin may exert any beneficial impact directly on cognition at the neural circuitry level and the behavioral level has not been investigated. Methods: In the current study, we took advantage of gintonin, a novel LPAR agonist, to investigate the effect of gintonin-mediated LPAR activation on cognitive performances. Hippocampus-dependent fear memory test, synaptic plasticity in the hippocampal brain slices, and quantitative analysis on synaptic plasticity-related proteins were used. Results: Daily oral administration of gintonin for 1 wk significantly improved fear memory retention in the contextual fear-conditioning test in mice.We also found that oral administration of gintonin for 1 wk increased the expression of learning and memory-related proteins such as phosphorylated cyclic adenosine monophosphate-response element binding (CREB) protein and brain-derived neurotrophic factor (BDNF). In addition, prolonged gintonin administration enhanced long-term potentiation in the hippocampus. Conclusion: Our observations suggest that the systemic gintonin administration could successfully improve contextual memory formation at the molecular and synaptic levels as well as the behavioral level. Therefore, oral administration of gintonin may serve as an effective noninvasive, nonsurgical method of enhancing cognitive functions.

• Perspectives in Nursing Science
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• v.14 no.1
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• pp.37-44
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• 2017

Purpose: This study aimed to provide information on the developmental process and current status of Advanced Practice Nurses (APN) and to suggest ways for activating APN roles in Korea. Methods: We reviewed literatures to explore domestic and international trends related to the roles, practice settings, scope of practice, regulatory policies, and political environment of APN. Results: Interest in the APN role has been gaining ground worldwide. While the roles of APN in the USA, Taiwan and Japan have been changed in terms of legislation and institutional regulations, the role of APN in 12 fields except for APN in home care has not been legislated since qualification was specified in Korean Medical Law. Many problems were found in vitalizing APN roles: absence of legal regulations on the scope of practice or health insurance coverage for APN, increase the number of medical support staffs who are not qualified, and a disagreement regarding the qualification field and practical field. Conclusion: This study presents snapshots and vitalizing strategies of practice, and regulation for APN to develop their unique roles in Korea. The tasks and duties of APN should be identified specifically to fulfill their roles. In terms of national health insurance policy APN's Nursing care should be reimbursed just as nursing care of APN in home care.

• Journal of National Security and Military Science
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• s.2
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• pp.121-163
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• 2004

Science technique development expanded into, not only land, sea, and air operations but also those of airspace, and cyber battle spaces. It is generally accepted at this time that space centric operations currently cannot be effectively divided from air operations. However, science and technology advancements make it possible to integrate Army, Navy, Airforce, and Marine forces into effective operations as never before. The Republic of Korea Armed Forces needs to establish a more effective joint concept. The US military, considered by many experts as the most effective in the world, understands the necessity of joint operations and accordingly has highly developed its own concept of joint operations. The US joint operational concepts demonstrated their effectiveness during the Iraqi War by dominating the battlefield through effective use of all combat and non-combat power. Following the US Iraqi War experience, the US Department of Defense continued to enhance Joint Capability through the acceleration of US Military Transformation involving all components. The future national security of the Republic of Korea, faced with the peculiarity of communist threat in the form of North Korea, and the conflicting interest of four strong powers; the United States, China, Japan, and Russia, depends on small but strong armed forces employing all available combat power through effective National and Military Strategy, and considering domestic and international constraints. In order to succeed in future wars, military operations following joint operational concepts must effectively employ all available combat power in a timely manner. The Republic of Korea Armed Forces must establish a joint forces concept in order to integrate all available combat power during employment. Therefore we must establish military operations that develop the military structure and organization, doctrine, weapon systems, training and education of our armed forces based on the key concept of joint operations.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.16 no.4
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• pp.54-63
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• 2017

With the aim of promoting the use of metropolitan railways, the present research developed a mode choice model for evaluating its competitiveness against passenger cars. A case study was carried out with Gyeongeui and Joongang line, and the area of interest was the direct operating railway between Ilsan and Guri station where the two lines intersect. The mode choice model was a disaggregate behavior model which used Stated Preference (SP) survey data, and the plot of competition was between private passenger cars and express trains. As a result, the mode choice model was established, and this model was used to analyze characteristics of passengers' time value and elasticity. It was shown that reducing travel time is more efficient than reducing travel cost when it comes to operating express trains in metropolitan railways. Therefore, policies designed for activating the use of metropolitan railways should expand direct operating service of individual lines and run more express trains in order to minimize transfer and in-vehicle time.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.10 no.3
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• pp.145-152
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• 2010

With the recent development of the ubiquitous computing technology, there are increasing interest and research in technologies such as sensors and RFID related to information recognition and location positioning in various ubiquitous fields. Especially, RTLS(Real-Time Locating Services) dealing with spatio-temporal data is emerging as a promising technology. For these reasons, the ISO/IEC published the RTLS standard specification for compatibility and interoperability in RTLS. Therefore, in this paper, we designed and implemented Spatio-temporal Query Processing Systems for efficiently managing and searching the incoming Spatio-temporal data stream of moving objects. Spatio-temporal Query Processing Systems's spatio-temporal middleware maintains interoperability among heterogeneous devices and guarantees data integrity in query processing through real time processing of unceasing spatio-temporal data streams and two way synchronization of spatio-temporal DBMSs. Web Server uses the SOAP(Simple Object Access Protocol) message between client and server for interoperability and translates client's SOAP message into CQL(Continuous Query Language) of the spatio-temporal middleware. Finally, this thesis proved the utility of the system by applying the spatio-temporal Query Processing Systems to a real-time Locating Services.

• The Journal of Korean Association of Computer Education
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• v.12 no.5
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• pp.35-47
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• 2009

Just as noted in some studies related to U-learning based on the ubiquitous technology, it is required to reflect both factors of the environments and contexts of learners on the teaching and learning strategy. For this, the current paper suggests an inquiry learning method and a mobile learning support device for the inquiry learning. Since the inquiry learning is operating on the basis of the contents that learners themselves experience in the fields, it naturally leads them to position in the learning environments and contexts. In this study some curricula are adopted and transformed for the inquiry learning, and the developed mobile device for the learning has a guide function, so that learners might follow the inquiry learning process. In addition, it is possible to reuse the acquired learning data by storing them on a remote learning sever, which may support the inquiry learning of students. These system and device are applied in the teaching sites of schools and, consequently, it is found that in regard with the learning interest and academic performance of students there is an advanced result, being statistically significant.

• The Journal of Korean Association of Computer Education
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• v.12 no.5
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• pp.1-13
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• 2009

Systematic information protection education is necessary to evoke the importance of information protection to the students and to provide them with alternatives to cope with malicious attacks. However, there have been too little development of the methods of systematic education and teaching materials to allow an effective education of information protection in the classrooms today. In this paper, we developed principle-oriented visual learning materials using UCC (User Created Content) for an effective education of information protection and evaluated the effectiveness of our approach with independent sample t-test method after being used in two classes, a test group and a control group. In particular, using UCCs, which have become the most frequently used contents in the Internet, as visual material for the education of information protection, proved to be effective in promoting the interest of students in classes and highly useful in education.

• The Journal of Korean Association of Computer Education
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• v.15 no.2
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• pp.57-66
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• 2012

It is the advantage of robot programming to improve the learners' interest. However, the drawback is existed in the fact that it is not easy to determine whether the problem lies in the hardware factor or programmed logic when an error takes place. This study is an attempt to develop a simulation tool which assists learners to concentrate on the problems not relating to robot assembling but to robot program. It aims to enable beginners make a sketch of their ideas and examine their logic through simulation. Therefore, an Etoys-based robot programming tool is developed to allows user to download and execute the simulated program into an assembled robot. The significance of this study is that easy activity of sketch-based simulation can support learners to understand how the principles of computer science are applied in daily life such as an automatic door system.

• International Commerce and Information Review
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• v.6 no.2
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• pp.107-127
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• 2004

The rapid development of internet information technology has increased interest in e-Trade these days, but it is not activated greatly up to now. In order to promote e-Trade, it is essential to construct cooperative process such as connecting systems among trade related parties. Building e-Trade platform which is based on the infrastructure of the past trade automatic system is key point of promoting e-Trade. To do this, a study on the basic concept and specific components of e-Trade platform is needed absolutely. At this point of view, after this paper has examined domestic and foreign studies on the fundamental technologies about electronic commerce, it drew several key technologies that could be applied to e-Trade considering the current IT trend. Then it evaluates these technologies according to Technology Reference Model(TRM) of the National Computerization Agency. This will help us to show the operation strategy as well as the concept of future e-Trade platform and its composition. On the basis of the theoretical background, this paper classified NCA's technology model into 6 fields, which are application. data, platform, communication, security and management. Considering the key technologies, e-Trade platform has to be mutually connected and accept international standards such as XML. In the aspect of business side, trade relative agencies' business process as well as trading company's process has to be considered. Therefore, e-Trade platform can be classified into 3 parts which are service, infrastructure and connection. Infrastructure part is compared of circulating and managing system of electronic document, interface and service framework. Connecting service (application service) and additional service (application service) consist of service part. Connecting part is a linking mutual parts and can be divided into B2B service and B20 service. The organization operating this e-trade platform must have few responsibilities and requirements. It needs to positively accept existing infrastructure of trade automatic system and improving the system to complete e-trade platform. It also have to continuously develop new services and possess ability to operate the system for providing proper services to demanders. As a result, private sector that can play a role as TTP(Third Trust Party) is adequate for operating the system. In this case, revising law is necessary to support the responsibility and requirement of private sector.

• The Research Journal of the Costume Culture
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• v.23 no.1
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• pp.32-44
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• 2015

Increasing of Korean old women's rate is demographic characteristics attributed an aging society, silver generation would lead to silver fashion market with steady competitiveness and interest in fashion. So the study attempts to use foundation material for silver's fashion design by analyzing design characteristics and processing development of design representative women's top. Selecting brand for collecting photo using study represents a mid- and premium-priced with reference Brand Yearbook. After selecting brand on domestic and foreign I have collected picture from Internet shopping mall and web-site of fashion brand, from October 2013 to July 2014, but I selected 840 pictures based on front poses for easy decision. In order to search design characteristics according to sort of silver blouse design on domestic and foreign. I have examined shape, color, pattern, fabric sensation, inside composition line and decoration with reference standard of analysis in preceding research. Data analysis method was conducted on analysis of frequency and cross analysis using SPSS statistical package 21.0. The conclusion of design characteristic according to type of blouse design for silver, H-silhouette in shirt blouse seems to fit in body transformation and expose silhouette with correcting the body flaw. Using soft material in T-shirt blouse they are able to conceal a body defect and express beautiful silhouette. By using detail in pullover shirt blouse and tunic blouse for point of design, it express glamour and luxurious. Most of blouse are printed various pattern, it would looks more gorgeous using pattern.