• International Journal of Computer Science & Network Security
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• v.21 no.3
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• pp.41-47
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• 2021

Detection of protein-protein interactions (PPIs) remains essential for the development of therapies against diseases. Experimental studies to detect PPI are longer and more expensive. Today, with the availability of PPI data, several computer models for predicting PPIs have been proposed. One of the big challenges in this task is feature extraction. The relevance of the information extracted by some extraction techniques remains limited. In this work, we first propose an extraction method based on correlation relationships between the physicochemical properties of amino acids. The proposed method uses a correlation matrix obtained from the hydrophobicity and hydrophilicity properties that it then integrates in the calculation of the bigram. Then, we use the SVM algorithm to detect the presence of an interaction between 2 given proteins. Experimental results show that the proposed method obtains better performances compared to the approaches in the literature. It obtains performances of 94.75% in accuracy, 95.12% in precision and 96% in sensitivity on human HPRD protein data.

• Structural Engineering and Mechanics
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• v.61 no.3
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• pp.335-345
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• 2017

Free vibration analysis for continuous bridge under any number of vehicles is conducted in this paper. Calculation strategy for natural frequency and mode shape is proposed based on Euler-Bernoulli beam theory and numerical assembly method. Firstly, a half-car planar model is adopted; equations of motion and displacement functions for bridge and vehicle are established, respectively. Secondly, the undermined coefficient matrices for wheels, vehicles, intermediate support, left-end support and right-end support are derived. Then, the numerical assembly technique for conventional finite element method is adopted to construct the overall matrix of coefficients for whole system. Finally, natural frequencies and corresponding mode shapes are determined based on iterative method and overall matrix solution. Numerical simulation is presented to verify the effectiveness of the proposed method. The results reveal that the solutions of present method are exact ones. Natural frequencies and associate modal shapes of continuous bridge under different conditions of vehicles are investigated. The influences of vehicle parameters on natural frequencies are also demonstrated.

• Journal of the Korean Institute of Telematics and Electronics
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• v.26 no.8
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• pp.1161-1166
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• 1989

In this paper, a hierarchical state feedback control method is proposed for the optimal tracking of large-scale discrete-time systems with time-delays. The state feedback gain matrix and the compensation vector are computed from the optimal trajectories of the state variables and control inputs obtained hierarchically by the open-loop control method based on the interaction prediction method. The resulting feedback gain matrix and the compensation vector are optimal for the given initial condition. Computer simulation results show that the proposed method has better control performance and fewer second level iterations than the Tamura method.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.22 no.3
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• pp.156-164
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• 2010

Combustion instability is a major issue in design of gas turbine combustors for efficient operation with low emissions. Combustion instability is induced by the interaction of the unsteady heat release of the combustion process and the change in the acoustic pressure in the combustion chamber. In an effort to develop a technique to predict self-excited combustion instability of gas turbine combustors, a new stability analysis method based on the transfer matrix method is developed. The method views the combustion system as a one-dimensional acoustic system with a side branch and describes the heat source as the input to the system. This approach makes it possible to use not only the advantages of the transfer matrix method but also well established classic control theories. The approach is applied to a gas turbine combustion system, which shows the validity and effectiveness of the approach.

• Proceedings of the SAREK Conference
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• 2009.06a
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• pp.1449-1457
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• 2009

Combustion instability is a major issue in design of co-generation gas turbine combustors for efficient operation with low emissions. Combustion instability is induced by the interaction of the unsteady heat release of the combustion process and the change in the acoustic pressure in the combustion chamber. In an effort to develop a technique to predict self-excited combustion instability of co-generation gas turbine combustors, a new stability analysis method based on the transfer matrix method is developed. The method views the combustion system as a one-dimensional acoustic system with a side branch and describes the heat source as the input to the system. This approach makes it possible to use not only the advantages of the transfer matrix method but also well established classic control theories. The approach is applied to a simple co-generation gas turbine combustion system, which shows the validity and effectiveness of the approach.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.14 no.3
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• pp.463-472
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• 1994

A method of stochastic response analysis of base-isolated fluid-filled pool structures subject to random ground excitations is studied. Fluid-structure interaction effects between the flexible walls and contained fluid are taken into account in the form of added mass matrix derived by FEM modeling of the contained fluid motion. The stationary ground excitation is represented by Modified Clough-Penzien spectral model and the nonstationary one is obtained by imposing an envelope function on the stationary one. The stationary and nonstationary response statistics of the two different isolation systems are obtained by solving the governing Lyapunov covariance matrix differential equations.

• Geomechanics and Engineering
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• v.2 no.4
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• pp.229-252
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• 2010

In this paper, Soil-Structure Interaction (SSI) effect is investigated using a new and integrated approach. Faster solution of time dependant differential equation of motion is achieved using numerical representation of wavelet theory while dynamic Infinite Elements (IFE) concept is utilized to effectively model the unbounded soil domain. Combination of the wavelet theory with IFE concept lead to a robust, efficient and integrated technique for the solution of complex problems. A direct method for soil-structure interaction analysis in a two dimensional medium is also presented in time domain using the frequency dependent transformation matrix. This matrix which represents the far field region is constructed by assembling stiffness matrices of the frequency dependant infinite elements. It maps the problem into the time domain where the equations of motion are to be solved. Accuracy of results obtained in this study is compared to those obtained by other SSI analysis techniques. It is shown that the solution procedure discussed in this paper is reliable, efficient and less time consuming as compared to other existing concepts and procedures.

• Computational Structural Engineering : An International Journal
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• v.1 no.1
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• pp.31-38
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• 2001

In the case of the non-proportionally damped system such as the soil-structure interaction system, the structural control system and composite structures, the eigenproblem with the damping matrix should be necessarily performed to obtain the exact dynamic response. However, most of the eigenvalue analysis methods such as the subspace iteration method and the Lanczos method may miss some eigenvalues in the required ones. Therefore, the eigenvalue analysis method must include a technique to check the missed eigenvalues to become the practical tools. In the case of the undamped or proportionally damped system the missed eigenvalues can easily be checked by using the well-known Sturm sequence property, while in the case of the non-proportionally damped system a checking technique has not been developed yet. In this paper, a technique of checking the missed eigenvalues for the eigenproblem with the damping matrix is proposed by applying the argument principle. To verify the effectiveness of the proposed method, two numerical examples are considered.

• Journal of the Society of Naval Architects of Korea
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• v.42 no.4 s.142
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• pp.396-401
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• 2005

In this study, the assumed mode method using characteristic polynomials of Timoshenko beam is applied to the free vibration analysis for the stiffened plate of ship tank side in contact with water. The hydro-elastic effect of the fluid-structure interaction is considered by fluid velocity potential, derived from boundary conditions for fluid and structure, and utilized in the calculation of added mass matrix using assumed modes. To verify the validity and effectiveness of the presented method, free vibration analysis for the stiffened plates in contact with finite and infinite fluids have been carried out and its results were compared with those obtained by a general purpose FEA software.

• Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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• 2004.11a
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• pp.271-276
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• 2004

In this paper. dynamic behavior of the cracked beam under a moving mass is presented using the finite element method (FEM). Model accuracy is improved with the following consideration: (1) FE model with Timoshenko beam element (2) Additional flexibility matrix due to crack presence (3) Interaction forces between the moving mass and supported beam. The Timoshenko bean model with a two-node finite element is constructed based on Guyan condensation that leads to the results of classical formulations. but in a simple and systematic manner. The cracked section is represented by local flexibility matrix connecting two unchanged beam segments and the crack as modeled a massless rotational spring. The inertia force due to the moving mass is also involved with gravity force equivalent to a moving load. The numerical tests for various mass levels. crack sizes. locations and boundary conditions were performed.