• Title/Summary/Keyword: interaction curves

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An Analysis Model of the Secondary Tunnel Lining Considering Ground-Primary Support-Secondary Lining Interaction (지반-1차지보재-2차라이닝의 상호작용을 고려한 터널 2차라이닝 해석모델)

  • 서성호;장석부;이상덕
    • Tunnel and Underground Space
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    • v.12 no.2
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    • pp.107-114
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    • 2002
  • It is the common practice to over design the reinforcement for the secondary tunnel lining due to the lack of rational insight into the ground loosening loads. and due to the conservative application of the empirical design methods. The main loads of the secondary lining are the ground Loosening loads and the ground water pressure, and the ground load is critical in the reinforcement design of the secondary lining in the case of drained tunnel. If the external load is absent around a tunnel, the reasons of the load far secondary tunnel lining are the deterioration of the primary supports such as shotcrete, steel rib, and rockbolts. Accordingly, the analysis method considering the ground-primary supports-secondary lining interaction should be required tar the rational design of the secondary tunnel lining. In this paper, the interaction was conceptually described by the simple mass-spring model and the load transfer from the ground and primary supports to the secondary lining is showed by the ground-primary supports-secondary lining reaction curves fur the theoretical solution of a circular tunnel. And also, the application of this proposed model to numerical analysis is verified in order to check the potential far the tunnel with the complex analysis conditions.

Development of Jaspine B analysis using LC-MS/MS and its application: Dose-independent pharmacokinetics of Jaspine B in rats

  • Song, Im-Sook;Jeon, Ji-Hyeon;Lee, Jihoon;Lim, Dong Yu;Lee, Chul Haeng;Lee, Dongjoo;Choi, Min-Koo
    • Analytical Science and Technology
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    • v.34 no.2
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    • pp.37-45
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    • 2021
  • A rapid and simple LC-MS/MS analytical method in determining Jaspine B has been developed and validated in rat plasma. The standard curve value was 25 - 5000 ng/mL and the linearity, inter-day and intra-day accuracy and precision were within 15.0 % of relative standard deviation (RSD). The mean recoveries of Jaspine B ranged from 87.5 % to 91.2 % with less than 3.70 % RSD and the matrix effects ranged from 91.1 % to 108.2 % with less than 2.6 % RSD. The validated LC-MS/MS analytical method of Jaspine B was successfully applied to investigate the dose-escalated pharmacokinetic study of Jaspine B in rats following an intravenous injection of Jaspine B at a dose range of 1 - 10 mg/kg. The initial plasma concentrations and area under plasma concentration curves showed a good correlation with intravenous Jaspine B dose, indicating the dose independent pharmacokinetics of Jaspine B in rats. In conclusion, this analytical method for Jaspine B can be easily applied in the bioanalysis and pharmacokinetic studies of Jaspine B, including its administration at multiple therapeutic doses, or for making pharmacokinetic comparisons for the oral formulations of Jaspine B in small experimental animals as well as in vivo pharmacokinetic-pharmacodynamic correlation studies.

Development of Adhesion Force Measurement Apparatus with High Stiffness and High Resolution (고탄성 고분해능을 갖는 응착력 측정장치의 개발)

  • Kim, Gyu-Sung;Yoon, Jun-Ho
    • Journal of the Korean Society for Precision Engineering
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    • v.24 no.3 s.192
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    • pp.140-146
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    • 2007
  • To understand adhesive phenomena, we need to get force curve between two surfaces. And it is said that high stiffness force analysis system is needed to get precise force curve and more information of the surfaces. Usually the stiffness of the force measurement system is under the order of 10N/m. The stiffer force measurement system, however, results in more information on the surface, because higher stiffness lead to the wider range of force curves, secondly because the force curve obtained through the stiffer one describes more precise relationship between relative tip-sample separation and interaction force. In this paper, considering for stiffness and resolution, the cantilever was designed and we made adhesion force measurement apparatus with high stiffness and high resolution, so we measured adhesive force between Ag-ball and wafer.

The EC3 approach to the design of columns, beams and beam-columns

  • Nethercot, D.A.;Gardner, L.
    • Steel and Composite Structures
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    • v.5 no.2_3
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    • pp.127-140
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    • 2005
  • Procedures given in Eurocode 3 Part 1.1 (EN 1993-1-1) for design of the main types of structural member under given systems of loading are presented and described. Whereas some of these e.g. the procedure for axially loaded columns, are little changed from the early concept that appeared more than 25 years ago in the European Recommendations and have subsequently been adopted in many other steel codes of the world, others such as the interaction formulae for beam-columns are new, with aspects of the provisions still under development. For each type of member the basis of the procedure is described and some comparative comments made.

Bayesian Logistic Regression for Human Detection (Human Detection 을 위한 Bayesian Logistic Regression)

  • Aurrahman, Dhi;Setiawan, Nurul Arif;Lee, Chil-Woo
    • 한국HCI학회:학술대회논문집
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    • 2008.02a
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    • pp.569-572
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    • 2008
  • The possibility to extent the solution in human detection problem for plug-in on vision-based Human Computer Interaction domain is very attractive, since the successful of the machine leaning theory and computer vision marriage. Bayesian logistic regression is a powerful classifier performing sparseness and high accuracy. The difficulties of finding people in an image will be conquered by implementing this Bavesian model as classifier. The comparison with other massive classifier e.g. SVM and RVM will introduce acceptance of this method for human detection problem. Our experimental results show the good performance of Bavesian logistic regression in human detection problem, both in trade-off curves (ROC, DET) and real-implementation compare to SVM and RVM.

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Binding of Acid Dyes by Crosslinked Poly(4-vinylpyridine) in Ethylene Glycol (에틸렌글리콜중에서 가교폴리(4-비닐피리딘)과 산성염료와의 결합)

  • Lee, Suk Kee;Kim, Woo Sik
    • Textile Coloration and Finishing
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    • v.9 no.3
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    • pp.27-32
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    • 1997
  • Two poly(4-vinylpyridines) having different degree of crosslinking were prepared by radical copolymerization of 4-vinylpyridine with N, N'-tetramethylenebis-acrylamide as a crosslinker. The abilities of these crosslinked polymers to bind acid dyes (methyl orange, ethyl orange, and propyl orange) were investigated at various temperatures in ethylene glycol as the binding medium. From the equilibrium amounts, the first binding constants and thermodynamic parameters for the bindings were evaluated. The first binding constants and thermodynamic parameters were not varied with these dyes. This result indicates that there is no hydrophobic interaction between the crosslinked polymers and the dyes in ethylene glycol. However, the first binding constants showed bell-shaped curves againtst the binding temperatures. This result could be explained in terms of the crosslinked hole size with temperature variation.

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A Consideration on the Characteristics of Electron Beam Dose Distributions for Clinical Applications (임상적용을 위한 전자선의 선량분포 특성에 대한 고찰)

  • Cha, Dong-Soo
    • Korean Journal of Digital Imaging in Medicine
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    • v.12 no.1
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    • pp.65-69
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    • 2010
  • High energy electron beams were to concentrically dose inside a tumor and more energy is a shape decreased of dose. Therefore, it is useful to radiation therapy of a tumor. Also high energy electron beams ionized into collision with a atom in structure material of tissue and it has big changes to dose distribution by multiple scattering. The study had to establish characteristic of electron beams from interaction of electron beams and materials. Experiment method was to measure dependence of electron beam central axis for depth dose curve, field flatness and symmetry and field size dependence. The results were able to evaluate data for a datum pint of electron beam. Also radiotherapy has to be considered for not only energy pencil of lines but characteristic, electron guide and isodose curves distribution.

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Surface effects on flutter instability of nanorod under generalized follower force

  • Xiao, Qiu-Xiang;Zou, Jiaqi;Lee, Kang Yong;Li, Xian-Fang
    • Structural Engineering and Mechanics
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    • v.64 no.6
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    • pp.723-730
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    • 2017
  • This paper studies on dynamic and stability behavior of a clamped-elastically restrained nanobeam under the action of a nonconservative force with an emphasis on the influence of surface properties on divergence and flutter instability. Using the Euler-Bernoulli beam theory incorporating surface effects, a governing equation for a clamped-elastically restrained nanobeam is derived according to Hamilton's principle. The characteristic equation is obtained explicitly and the force-frequency interaction curves are displayed to show the influence of the surface effects, spring stiffness of the elastic restraint end on critical loads including divergence and flutter loads. Divergence and flutter instability transition is analyzed. Euler buckling and stability of Beck's column are some special cases of the present at macroscale.

A Improved Method of Determining Everett Function with Logarithm Function and Least Square Method

  • Hong, Sun-Ki
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.22 no.7
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    • pp.16-21
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    • 2008
  • For Preisach model, Everett function from the transient curves is needed to simulate the hysteresis phenomena. However it becomes very difficult to get the function if the it would be made only from experiments. In this paper, a simple and stable procedure using least square method and logarithm function to determine the Everett function which follows the Gauss distribution for interaction field axis is proposed. The characteristics of the parameters used in this procedure are also presented. The proposed method is applied to implement hysteresis loops. The simulation for hysteresis loop is compared with experiments and good agreements could be shown.

Bearing capacity of geotextile-reinforced sand with varying fine fraction

  • Deb, Kousik;Konai, Sanku
    • Geomechanics and Engineering
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    • v.6 no.1
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    • pp.33-45
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    • 2014
  • Use of geotextile as reinforcement material to improve the weak soil is a popular method these days. Tensile strength of geotextile and the soil-geotextile interaction are the major factors which influence the improvement of the soil. Change in fine content within the sand can change the interface behavior between soil and geotextile. In the present paper, the bearing capacity of unreinforced and geotextile-reinforced sand with different percentages of fines has been studied. A series of model tests have been carried out and the load settlement curves are obtained. The ultimate load carrying capacity of unreinforced and reinforced sand with different percentages of fines is compared. The interface behavior of sand and geotextile with various percentages of fines is also studied. It is observed that sand having around 5% of fine is suitable or permissible for bearing capacity improvement due to the application of geosynthetic reinforcement. The effectiveness of the reinforcement in load carrying capacity improvement decreases due to the addition of excessive amount of fines.