• 제목/요약/키워드: integration archives

검색결과 40건 처리시간 0.026초

Determination of ampicilin and colxacilin mixture by NMR

  • Shin, Moon-Hee;Park, Man-Ki;Yu, Chang-Hwa;Choi, Jung-Kap
    • Archives of Pharmacal Research
    • /
    • 제4권1호
    • /
    • pp.9-17
    • /
    • 1981
  • A simple, accurate and specific NMR procedure is described for the determination of amplicilin and cloxacillin mixtures in injection dosage form and capsules. The solvent was dimethysulfoxde $d_{6}$ and maleic acid was the internal standard. By integrating the peak at 2.68 ppm and 4.57 ppm, cloxacillin and ampicillin could be determined respectively. The relative proton ratio of ampicillin trihydrate and cloxacillin were 1.038 and 0.950. The coefficents of variation of amplicillin trihydrate and cloxacillin in a few commerical preparation were 1.55 % (n =9), 2.69 % (n =15).

  • PDF

Bioinformatics in the Post-genome Era

  • Yu, Ung-Sik;Lee, Sung-Hoon;Kim, Young-Joo;Kim, Sang-Soo
    • BMB Reports
    • /
    • 제37권1호
    • /
    • pp.75-82
    • /
    • 2004
  • Recent years saw a dramatic increase in genomic and proteomic data in public archives. Now with the complete genome sequences of human and other species in hand, detailed analyses of the genome sequences will undoubtedly improve our understanding of biological systems and at the same time require sophisticated bioinformatic tools. Here we review what computational challenges are ahead and what are the new exciting developments in this exciting field.

Mixed Use Complex 디자인에 관한 연구 -업무/상업/문화오락/주거기능 복합의 사례분석을 중심으로- (A Study on the Mixed Use Complex Design)

  • 이혜진
    • 디자인학연구
    • /
    • 제21권
    • /
    • pp.207-217
    • /
    • 1997
  • Mixed Use Area (Multifaceted Integration) is getting increasingly demanded since it has several merits such as preventing CBD from being emptied during night time, making daily life comfortable and utilizing the land more efficiently. However, the characteristic of Mixed Use Area -as advantages of it-, which is that it combines residence, retail, office, cultural, entertainment facilities altogether could be regarded as a weakness when it is viewed from each functions' original purposes such as residential and retail areas'. Accordingly, it is needed to do basic research and develop design guidelines of the Mixed Use Area to prepare its another take-off. The purpose of this research is to study theoretical background of Mixed Use Area's birth, understand its status quo by examining examples overseas and presented possible standardized ways of developing it.

  • PDF

기록관의 새로운 모델, 통합기록관 교육청 기록관 체계의 재편성 (A New Model of Records Centers, Integration Archives : Reoranization of the Education office Records Centers)

  • 임희연
    • 기록학연구
    • /
    • 제58호
    • /
    • pp.31-63
    • /
    • 2018
  • 공공기관의 기록관리 정착화를 위해 가장 우선시 되어야 할 점은 기관 내 기록관의 기능 및 역할 강화와 기록물관리 전문요원의 전문성 발휘를 위한 조직과 인력의 기반 조성이다. 그러나 현재 공공기록물법에서의 '기록관' 개념과 여기에 근무하는 '기록물관리 전문요원 배치 기준'은 기관마다 주관적으로 해석할 여지가 많아 현장에 여러 가지 문제점이 나타나고 있다. 이러한 현안을 해결하기 위해 이제는 보다 구체적인 개선방안이 필요할 때이다. 본 연구에서는 교육청 환경을 중심으로 본청과 교육지원청 기록관 체계에서 나타나는 문제점을 분석하였다. 본청에 모든 권한이 집결된 조직구조 속에 실체 없는 교육지원청의 기록관, 기록물폐기사로 전락한 기록물관리 전문요원의 현실 등, 이러한 문제해결 방안으로 기록물관리 전문요원 배치기준 변경, 집중근무방식을 반영한 통합기록관 운영, 교육관련 기관을 위한 기록관리 특례법 제정을 제안하였다.

디지털 시대의 제품 이미지 통합화 방안에 관한 연구 (A Study of the image integration of Product in the digital age)

  • 김기수;정병로
    • 디자인학연구
    • /
    • 제12권4호
    • /
    • pp.89-98
    • /
    • 1999
  • 제품개발에 있어 도구의 활용은 시대별로 급속하게 발전되어 사용되었고 오늘날과 같은 컴퓨터 디지털화는 대부분의 공장제 대향생산체계에서 필수 불가결한 공정으로 자리 매김 하였다. 이러한 환경변화에서 제품의 기획단계부터 최종 양산단계에 이르기까지 디자이너의 감성적 욕구를 체계적이고 합리적인 정보환경구축으로 디지털화 함으로써 최종 소비자인 고객의 다양한 요구를 만족시켜야 한다. 시대의 패자(覇者)가 되고자 하는 기업은 앞다투어 정보를 효율적으로 처리하는 유용한 도구럿 컴퓨터를 도입하였고, 이러한 컴퓨터는 인간보다 훨씬 우수한 계산능력을 발휘하여 그 기대에 부응하였으며 전자기술의 발전에 힘입어 컴퓨터의 고성능화, 경제화, 소형화, 통합화를 기능하게 만들어 우리의 디자인 개발환경은 과거와 비교할 수 없을 정도로 많은 정보를 접할 수 있게 되었다. 그렇지만 아무리 좋은 정보라도 사용되고 활용되지 않으면 의미가 없기 때문에 어디서든 필요에 따라 그 정보를 취할 수 있어야 한다. 따라서 본 연구는 디지털 컴퓨터의 소형화, 통합화 발전동향 및 정보화사회에 있어 컴퓨터 통신의 미래기능성을 살피고 정보화된 디자인 환경과 제품 이미지 동일화 디자인 전략을 컴퓨터에 의한 응용 프로그램의 활용으로 디자이너의 다각화된 신제품 개발능력을 향상기킬 수 있는 방안을 모색한다.

  • PDF

전자정부 추진과 기록관리방안 (A Study on the Promotion of Electronic Government and Plans for Archival Management)

  • 김재훈
    • 기록학연구
    • /
    • 제5호
    • /
    • pp.39-85
    • /
    • 2002
  • This paper is aimed at proposing the policies for managing archives in the process of promoting Electronic Government System. Although there have been many studies of electronic government project and plans for its establishment, this research examines the electronic government system and its problems on the basis of archival science. What I acquired in this paper is as follows. The development of information technology needs great changes ranging from the nation to the individuals. It becomes common that the use of computerized program for business purposes, computerization of information materials and the effective way of search use of electronic documents. Therefore, more and more countries all over the world have been seeking to promote 'Electronic Government', which applies the fruits of the development in information technology to administration process. Recently, Korea has been rapidly entered into the 'Electronic Government' system being against the traditional way of administration. In electronic government system, the 'Life Cycle' of public records will be computerized. Therefore, it is important to change and develop along with the government's policies for 'electronic government project' in the archival management system. This means that the archival management system which have put emphasis on the textual records should be converted to electronic records system. In other words, the records management in electronic government system requires not the transfer and preservation of the records but the consistent management system including the whole process of creating, appraising, arranging, preserving and using the records. So, the systematic management of electronic records plays an important role in realization of electronic government, but it is a subject to be realized by electronic government at the same time. However, the government have overlooked the importance of archival management for long time, especially the importance of electronic records management system. First of all, this research attempts to infer limits and problems through the theoretical considerations of the existing studies for electronic government and to clear up the relations between electronic government and archival management. Based on this, I'll seek to progress the study through reviewing the present condition of archival management in the process of promoting electronic government and suggesting the policies for enhancing the successful electronic government and the construction of scientific archival management system. Since early 1990, many countries in the world have been making every effort to concrete 'Electronic Government'. Using the examples in other nations, it is not difficult to recognize that the embodiment of electronic government is closely connected with the archival management policies. Korea have completed legal and institutional equipments including the new establishment of "Electronic Government Law" to realize electronic government. Also, Korea has been promoting electronic government with the Ministry of Government Administration and Home Affairs and Government Computer Center as a leaders. Though managing records, especially the management of electronic records is essential in electronic government system, we haven't yet discussed this section in Korea. This is disapproved by the fact the Government Archives and Records Service has played little role in promoting electronic government project. There are two problems relating this environment. First, present system can't meet the consistent 'Life Cycle' ranging from the creation to the preservation of electronic records. Second, the 'Life Cycle' of electronic records is divided into two parts and managed separately by GCC and GARS. The life of records is not end with the process raged from creation to distribution. On the other hand, the records are approved their value only whole procedures. Therefore, GARS should play a deading role in designing and establishing the archival management system. The answer to these problems, is as follows. First, we have to complete the electronic records management system through introducing ERMS not EDMS. This means that we should not change and develop towards ERMS simply with supplementing the current electronic records management system. I confirm that it is important and proper to establish ERMS system from the very beginning of the process of promoting electronic government. Second, I suggest the developmental integration of GARS and GCC. At present, the divided operations of GCC and GARS, the former is in charge of the management center for electronic business and the latter is the hub institution of managing nation's records and archives result in many obstacles in establishing electronic government system and accomplishing the duties of systematic archival management. Therefore, I conclude that the expansive movement towards 'National Archives' through the integration among the related agencies will make a great contribution to the realization of electronic government and the establishment of archival management system. In addition to this, it will be of much help to constitute and operate the 'Task Force' regarding the management of electronic records with the two institution as the central figures.

행정박물의 유형분류 및 선별방안에 관한 연구 (A Study on the Type Classification and Selection Methods of Archival Objects)

  • 이영학;김명훈;임은정
    • 기록학연구
    • /
    • 제17호
    • /
    • pp.115-156
    • /
    • 2008
  • 공공기관의 활동과 관련하여 생성된 행정박물은 문자로는 표현할 수 없는 상징성, 역사성 및 심미성과 함께 형상물로서의 가치가 크기 때문에 향후 전시 및 활용의 가치가 높다. 우리나라에서는 지난 2006년 "기록관리혁신 종합실천계획"을 통해 행정박물을 공공기록으로 인식하고 그에 대한 적극적인 관리의지를 표명하였다. 이와 함께 개정 기록관리법에서는 행정박물 역시 업무와 관련하여 생산 접수한 기록물의 범주에 포함시킴으로써, 모든 공공기관에서 행정박물을 관리케 할 수 있는 기반을 마련하였다. 행정박물을 기록으로 인식하고 관리의지를 명문화했다는 점은 이전과는 다른 개혁적 의도로 볼 수 있지만, 행정박물에 대한 개념 규정 및 이를 체계적으로 관리 보존할 수 있게 하는 방안은 아직 미비한 상태이다. 이에 본고에서는 행정박물 관리체계 구축방안 마련을 위한 일환으로, 행정박물의 유형분류 및 평가 문제를 고찰하였다. 행정박물의 관리체계 구축을 위해서는 우선적으로 행정박물에 대한 명확한 개념 규정 및 구체적인 유형 파악이 선행되어야 한다는 전제 하에, 실제 조사자료 및 현행 유관법령을 기반으로 행정박물의 정의 및 유형분류를 시도하였다. 또한 공공기관의 업무와 관련하여 생산 활용되는 물품 중 어떠한 대상을 행정박물로 획득하여 관리할 것인가를 고찰하기 위해, 행정박물 선별 상의 특성을 분석하였다. 이를 바탕으로 우리나라 행정박물 선별 체제 및 영구보존 대상 선별기준 마련을 위한 방안을 제시하였다.

Effect of Substituents on Benzenesulfonyl Motif of 4-Phenyl-1-arylsulfonylimidazolidinones for Their Cytotoxicity

  • Lee, Hui-Soon;Park, Kyung-Lae;Choi, Sang-Un;Lee, Chong-Ock;Jung, Sang-Hun
    • Archives of Pharmacal Research
    • /
    • 제23권6호
    • /
    • pp.579-584
    • /
    • 2000
  • To explore the effect of substituents' on phenyl motif on sulfonyl function of novel anticancer 4-phenyl-1-benzenesulfonylimidazolidinones (1), electron donating or withdrawing sub-stituents were introduced at 3 or 4-position and the analogs were tested against human lung (A549) and colon (HCT-15) cancer cell lines. Quantitative structure activity relation-ship of the 4-substituted series shows that only STERIMOL L values are well correlated. The increment of substituent's volume enhances the activity against both cell lines. The small substituent at 3-position additionally increases the activity. However naphthyl group in place of phenyl reduces the activity, Therefore the phenyl motif with sterically large substituent at 4-position and small substituent at 3-position may be important for their activity. Integration of these substituents' effects into the structural design led to discover the more potent analog, 4-phenyl-1-(N-acetylindoline-5-sulfonyl) imidazolidinone (1n).

  • PDF

A Modularized Approach to the Development of the Creativity Learning Program

  • Won, Kyung-Ah
    • 디자인학연구
    • /
    • 제20권2호
    • /
    • pp.103-116
    • /
    • 2007
  • Art education in design has repeatedly stressed the importance of developing creativity. In the digital period, however, which shows rapid change in both forms and contents, it needs to be equipped with more flexible and systematic ways of approaching to the creativity development, especially involved with cultural diversity of the digital world. This paper primarily proposes a maximally efficient, productive creativity learning program in which the integration of expressive media and communication generates a comprehensive network of communicative information in the development of digital technologies, which, consequently, brings forth valuable cultural contents of art. The amalgamation of Won (2006)'s Prism Effect, with distinctive three devices, and the facilitator factors, with two different facilitators such as self-controlled and controlled plays, would function as a catalyst for cultural diversity in the digital forms and contents of art. And this will, consequently, result in producing a number of practices that can be classified and assorted for a later performance. This paper thus suggests a roadmap of how to develop the creativity learning program in which two categories of facilitators based on three thinking devices function to classify four activities. In addition, selected activities are shaped as a creativity learning program by generating learning practices with the formalizing instructional strategy that fit into a specialized educational environment and learners. The samples of loaming practice design show guidelines for practice and the results of learning activity. Therefore, the eventual goal of this paper would be to establish a creativity learning program that constitutes a highly systematized and modularized database to maximize the efficiency and productivity of the creativity development.

  • PDF

3차원 구조 DRAM의 캐시 기반 재구성형 가속기 (A Cache-based Reconfigurable Accelerator in Die-stacked DRAM)

  • 김용주
    • 정보처리학회논문지:컴퓨터 및 통신 시스템
    • /
    • 제4권2호
    • /
    • pp.41-46
    • /
    • 2015
  • 컴퓨터 사용 환경이 모바일 시장 및 소형 전자기기 시장 등으로 다양해짐에 따라 저전력 고성능 시스템에 대한 요구도 커지고 있다. 3차원 die-stacking 기술은 한정된 공간에서 DRAM의 집적도과 접근 속도를 높여 차세대 공정방식으로 많은 연구가 되고 있다. 이 논문에서는 3차원 구조의 DRAM 로직층에 재구성형 가속기를 구현하여 저전력 고성능 시스템을 구성하는 방법을 제안한다. 또한 재구성형 가속기의 지역 메모리로 캐시를 적용하고 활용하는 방법에 대해서 논의한다. DRAM의 로직층에 재구성형 가속기를 구현할 경우 위치적인 특성으로 데이터 전송 및 관리에 필요한 비용이 줄어들어 성능을 크게 향상시킬 수 있다. 제안된 시스템에서는 최대 24.8의 스피드업을 기록하였다.