• 한국광과학회:학술대회논문집
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• 한국광과학회 1997년도 학술대회지
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• pp.22-22
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• 1997

• Asian Pacific Journal of Cancer Prevention
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• 제16권2호
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• pp.689-692
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• 2015

Background: Incorporation of molecular analysis of the epidermal growth factor receptor (EGFR) gene into routine clinical practice has shown great promise to provide personalized therapy of the non-small cell lung cancer (NSCLC) in the developed world. However, the genetic testing of EGFR mutations has not yet become routine clinical practice in territories remote from the central regions of Russia. Therefore, we aimed to study the frequency of major types of activating mutations of the EGFR gene in NSCLC patients residing in West Siberia. Materials and Methods: We examined EGFR mutations in exons 19 and 21 in 147 NSCLC patients (excluding squamous cell lung carcinomas) by real time polymerase chain reaction. Results: EGFR mutations were detected in 28 of the 147 (19%) patients. There were 19 (13%) cases with mutations in exon 19 and 9 cases (6%) in exon 21. Mutations were more frequently observed in women (42%, p=0.000) than in men (1%). A significantly higher incidence of EGFR mutations was observed in bronchioloalveolar carcinomas (28%, p=0.019) and in adenocarcinomas (21%, p=0.024) than in large cell carcinomas, mixed adenocarcinomas, and NOS (4%). The EGFR mutation rate was much higher in never-smokers than in smokers: 38% vs. 3% (p=0.000). The frequency of EGFR mutations in the Kemerovo and Tomsk regions was 19%. Conclusions: The incorporation of molecular analysis of the EGFR gene into routine clinical practice will allow clinicians to provide personalised therapy, resulting in a significant increase in survival rates and improvement in life quality of advanced NSCLC patients.

• 대한치위생과학회지
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• 제5권2호
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• pp.25-33
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• 2022

Background: This study was aimed at investigating factors influencing the selection of dental institutions for implant surgery among young adults (age: 20-64 years) and identifying differences in these factors according to general characteristics. Methods: We conducted an internet survey for approximately 2 months, from April to July 2022, and analyzed data from a total of 128 people. Dental institution selection factors included three items of convenience of transportation, five items of physical environment, three items of image of institution, five items of image of dental staff, five items of dental service, and four items of basic dental elements. The importance score for each item was investigated on a five-point scale. Results: The importance score for each dental institution selection factor was the highest for dental service (4.42 points), followed by basic dental element (4.00 points), physical environment (3.89 points), image of institution (3.81 points), convenience of transportation (3.76 points), and image of dental staff (2.78 points). The importance score for each item was the highest for dentists' technique, followed by cleanliness, reliability, and dentists' attitude. Women had higher average scores for all factors compared to men, with statistical significance in scores for convenience of transportation, physical environment, image of institution, dental service, and basic dental elements (p< 0.05). Conclusion: To attract patients seeking implants to a dental institution, attention should be paid to the patients' institution selection factors. In addition, the environment of a dental institution should be created in such a way that it favors patients' selection factors.

• World Technopolis Review
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• 제4권2호
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• pp.46-61
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• 2015

There is an implicit assumption in most regional innovation policy studies that once a policy has been made the policy will be implemented. This assumption is not valid for regional innovation policies formulated in many countries. This assumption rests upon certain political and organization conditions. It is frequently said that regional innovation system in Korea is one of the successful cases because of properly established institution for the implementation of innovation policies. The components of institution for innovation are defined in this article. For the analysis of institution for regional innovation system in Korea, three aspects such as organization, policies & programs, and governance structure were taken into account. Institution for regional innovation system in Korea is analyzed with three aspects: (1) organization for policy implementation, (2) innovation policy, and (3) governance structure. Firstly, organizations for innovation in Korea are composed of three categories such as organizations for policy formulation, organizations for policy implementation and agencies for coordination. Secondly, there are two categories of policies for innovation: (1) policies for the enhancement of national competitiveness and policies for the regional innovation capacity building, and (2) policies for fostering manpower and policy for regulatory reform. Thirdly, innovation governance in Korea is composed of three layer structure: (1) top level governance which is composed of two committee, three ministries and two agencies, (2) local level governance such as one innovation related offices and one center for regulatory reform, and (3) one category of agency for coordination as a regional platform.

• 아동학회지
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• 제32권3호
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• pp.121-142
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• 2011

This study explores the structural relationships between personal factors (young children's self-esteem and language ability) and environmental factors (mother's acculturation, parenting, and teacher's multi-cultural education attitude) on young children's adjustment to early childhood educational institution in multi-cultural families. 150 young children in multi-cultural families of aged 3, 4, and 5, their mothers, and 108 classroom teachers participated in this study. The results of this investigation reveal the following : (1) Mother's integrative acculturation significantly affected mother's parenting. (2) The relationship between mother's acculturation and young children's adjustment to early childhood educational institution in multi-cultural families are significantly mediated by mother's parenting and the young children's self-esteem. (3) Young children's language ability in multi-cultural families significantly affected their degree of adjustment to early childhood educational institution.

• 동의생리병리학회지
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• 제28권4호
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• pp.440-445
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• 2014

Korean medical system is unique system that has two medical system, Western medical institution and Korean medical institution. In this environment, patients who use each medical institution have different selection factors. The study explores the selection factors' difference of korean/western medical institutions. The empirical analysis of the surveyed data produced the following outcomes. The result of factor analysis, four factors were extracted. That was Human services, Costs and Physical Environment, Prestige and reputation, Public relations and reliability. Overall, the four selection factor importance scores of Korean medical institution were higher than western medical institution's. These findings show that there is a difference between korean and western medical institutions in terms of selection factors. After this study, More study about medical management and healthcare policy including korean medical characteristics is needed.

• 사상체질의학회지
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• 제23권1호
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• pp.87-97
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• 2011

1. Objectives: We aimed to derive using status of Sasang Constitutional herbal prescription and good effective one in specific disease. 2. Methods: We sent Questionnaire to 463 oriental medical doctor listed Korea Sasang Constitutional medicine from 2009 years. 10 to 11 and got back 191 questionnaire, which consisted of sex, age, clinical duration, working type, using status and effectiveness of Sasang Constitutional herbal prescription. 3. Results: - Digestive tract disease was especially most effective field, and circulatory, the endocrine, dermatology, psychopathy, urogenital disease went in order in western disease. - Spleen disease was especially most effective field, and the heart and circulatory, neuropsychiatry, lung, liver, psychopathy, gynecology disease went in order in oriental medicine pathology. - Chungshimyenja-tang was effective to neuropsychiatry and heart disease in Taeeumin, Hyangsayangwi-tang to disease related digestive system, Palmulgunja-tang to gynecology disease in Soeumin, Dockhalgiwhang-tang to diet disorder, Yanggeuksanwha-tang to heart and psychologic disease in Soyangin. 4. Conclusions: Constitutional prescription effected on special pathological symptom support weaken organ, and these result will help to make treatment standard and support clinical study of constitutional medicine.

• 천문학회보
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• 제42권1호
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• pp.32.2-32.2
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• 2017

Stars form in dense core within the molecular clouds. The prestellar cores provide information of the physical characteristics at the very early stages of star formation. The low dust temperature (<14K) of Planck cold clumps/cores (PGCCs) make them likely to be prestellar objects or at the very initial stage of protostellar collapse. We have been conducting the legacy surveys of Planck cold clumps with the JCMT, the TRAO 14-m and many other telescopes. We aim to study of the initial conditions of star formation and chemical evolutions of the cores in the different environments. From JCMT SCUBA-2 $850{\mu}m$ survey (SCOPE), we have already identified hundreds of dense cores, which may be at the earliest phase of star formation. Therefore in order to explore the chemical evolution of these dense cores, we used KVN telescopes in order to observe 75 well selected SCUBA-2 cores in many molecules as the follow-up project of KVN Pilot Observation of SCUBA-2. These observations will help advance our understanding of the propoerties of these SCUBA-2 cores in PGCCs.

• 한국병원경영학회지
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• 제12권4호
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• pp.1-21
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• 2007

The relaxation of the regulation in selection of medical institution allows patients to use their own judgement in choosing proper institution for their diseases. Since the change of the regulation, there should have been many changes in medical institution selection behavior. The analysis of the change in disease specific selection pattern is critical because there be an optimal selection criteria that ensure the efficient and effective utilization of medical resources. This study analysis the institution selection factors by comparing the choice among the cases of acute diseases, the cases of chronic diseases, inpatient services, outpatient services, and emergency medical service. The comparisons performed in terms of size, class and other characteristics of medical institutions. For the study the nationally surveyed database was used and the data were analyzed using logistic regression procedure. The results indicates that the primary care facilities were not properly utilized. This study speculates that the reason for the undesirable pattern of utilization is that the roles of primary care facilities in the healthcare delivery system was not clearly defined. Based on the results, the medical policy implications are discussed.

• 한국도서관정보학회지
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• 제6권
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• pp.187-211
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• 1979

Persons who are waiting for decision of the court concerning whether they are guilty or not after they are involved in the criminal case and detained in the special institution isolated from society, will desire to de found innocent and acquited or to be slightly punished. Inmates are the suspected persons and the accused persons who are detained in the correctional institution. They have the right to de assisted by lawyes in order to receive the favorable verdict in the court. However, the right of the poor and the ignorant, in reality, cannot be perfectly protected due to the imperfection and defect of the defense counsel system itself and its application. Therefore, as a means to guarantee the so-called access to the court, the fundamental constitutional right, the law libraries are established and the legal information services are provided to the inmates within the correctional institution in the advanced country such as the United States. In addition, the judicial precedent and the various kinds of professional organizations provide the managerial guide-lines for such libraries to enoughly collect materials and to provide the effective information services to the inmates. In order to furnish the management of the correctional institution of Korea with useful information, the legal information services, materials collected, and information service personnel of the law libraries within the correctional institution are minutely examined in this paper.