• Title/Summary/Keyword: inner production

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Effects of maternal undernutrition during late pregnancy on the regulatory factors involved in growth and development in ovine fetal perirenal brown adipose tissue

  • Yang, Huan;Ma, Chi;Zi, Yang;Zhang, Min;Liu, Yingchun;Wu, Kaifeng;Gao, Feng
    • Animal Bioscience
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    • v.35 no.7
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    • pp.1010-1020
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    • 2022
  • Objective: The experiment was conducted to evaluate the effects of maternal undernutrition during late pregnancy on the expressions of genes involved in growth and development in ovine fetal perirenal brown adipose tissue (BAT). Methods: Eighteen ewes with singleton fetuses were allocated to three groups at day 90 of pregnancy: restricted group 1 (RG1, 0.33 MJ metabolisable energy [ME]/kg body weight [BW]0.75/d, n = 6), restricted group 2 (RG2, 0.18 MJ ME/kg BW0.75/d, n = 6), and a control group (CG, ad libitum, 0.67 MJ ME/kg BW0.75/d, n = 6). The fetuses were removed at day 140 of pregnancy. All data were analyzed by using the analysis of variance procedure. Results: The perirenal fat weight (p = 0.0077) and perirenal fat growth rate (p = 0.0074) were reduced in RG2 compared to CG. In fetal perirenal BAT, the protein level of uncoupling protein 1 (UCP1) (p = 0.0001) was lower in RG1 and RG2 compared with CG and UCP1 mRNA expression (p = 0.0265) was decreased in RG2. The protein level of myogenic factor 5 (Myf5) was also decreased in RG2 (p = 0.0001). In addition, mRNA expressions of CyclinA (p = 0.0109), CyclinB (p = 0.0019), CyclinD (p = 0.0015), cyclin-dependent kinase 1 (CDK1) (p = 0.0001), E2F transcription factor 1 (E2F1) (p = 0.0323), E2F4 (p = 0.0101), and E2F5 (p = 0.0018) were lower in RG1 and RG2. There were decreased protein expression of peroxisome proliferator-activated receptor-γ (PPARγ) (p = 0.0043) and mRNA expression of CCAAT/enhancer-binding protein-α (C/EBPα) (p = 0.0307) in RG2 and decreased PPARγ mRNA expression (p = 0.0008) and C/EBPα protein expression (p = 0.0015) in both RG2 and RG1. Furthermore, mRNA expression of bone morphogenetic protein 4 (BMP4) (p = 0.0083) and BMP7 (p = 0.0330) decreased in RG2 and peroxisome proliferator-activated receptor co-activator-1α (PGC-1α) reduced in RG2 and RG1. Conclusion: Our observations support that repression of regulatory factors promoting differentiation and development results in the inhibition of BAT maturation in fetal perirenal fat during late pregnancy with maternal undernutrition.

Tapered production tubing design considering flow stability and production rate (유동안정성과 생산량을 고려한 2단 생산튜빙 디자인)

  • Kim, Sung-Il;Jo, Gyung-Nam;Choe, Jonggeun
    • Journal of Advanced Marine Engineering and Technology
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    • v.37 no.5
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    • pp.548-556
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    • 2013
  • A tapered production tubing with two different inner diameters has been suggested to increase production rates. In this research, various tapered tubing combinations are taken into account and possible tubing combinations are proposed to satisfy each objective. In previous studies, production enhancement was the main goal. However, this research also considers flow stability by analyzing tubing pressure traverse, liquid holdup, and operating conditions. For a reservoir assumed in this research, a tapered tubing of, 4.5 inch inner diameter(ID) and 2000 ft in length in the lower part and 5.5 inch ID and 8000 ft in the upper part, shows the highest net present value. Compared to a mono tubing, tapered tubings enable various tubing designs because they have smaller differences in frictional pressure loss. It is important to maintain low liquid holdup to prevent liquid loading. Smaller ID of tapered tubing in the lower part enables to achieve the object. In conclusion, it is identified that various tubing designs are achievable from the analyses of overall production operations depending on purposes specified.

A study on the flashes and filling defects of inner part and on problem-solving measures (내통의 플래시 및 충진불량에 대한 해결방법에 관한 연구)

  • Kim, Sei-hwan;Choi, Kye-kwang;Lee, Choon-kyu
    • Design & Manufacturing
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    • v.6 no.2
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    • pp.79-83
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    • 2012
  • Inner part is used as an insulator in wire fuses. After injection molding, inner part has been showed flashes, filling defects and deformation. After production, operators have to cut off flashes, one by one. this process leads to continuous low productivity and loss of source materials. This study focuses on identifying the causes for flashes, filling defects, clamping force of injectors, mold adhesion, resin of liquidity and others, and on resolving those issues.

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Development of Chestnut Peeling System (밤 박피 시스템 개발)

  • 김종훈;박재복;최창현
    • Journal of Biosystems Engineering
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    • v.22 no.3
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    • pp.289-294
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    • 1997
  • The chestnut is a well-known and important forest product in Korea. The annual production of chestnut is about 100, 000tons and its cultivating area is 80, 000ha. However, the peeling process of outer and inner skins of chestnut is very difficult due to hardness and adhesiveness of chestnut skin. The peeling process of chestnut was operated by manual work and the performance of chestnut peeling machine is very low. The purpose of this study is to develope the prototype of new chestnut peeling system. The hardness of chestnuts was tested with six different drying conditions and its range was from 949$g/mm^2$ to 2, 149$g/mm^2$. The hardness of chestnuts was decresed gradually during the drying process. The chestnut peeling Process includes sorting, storage, drying, outer skin cutting, flame peeling, continuous frictional skin peeling, and inner skin cutting operation. The developed chestnut peeling system consists of outer skin cutter, flame peeler, continuous frictional skin peeler and inner skin cutter. The system can peel domestic chestnuts at 150$kg/hr$ with peeling rate of 78%.

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Robust Force Control of Pneumatic Manipulator (공압 매니퓰레이터의 강인 힘제어)

  • Park, Jeong-Gyu;Noritsugu, Toshiro
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.20 no.2
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    • pp.540-552
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    • 1996
  • In this paper, a compensation method of disturbance using a disturbance observer is proposed for a force control of a pneumatic robot manipulator. The generated torque by a pneumatic actuator can be estimated based on the pressure signals. The inner torque control system is constructed by feeding back the generated torque to improve the dynamic characteristics of the actuator. In order to reduce the influence of disturbances comprising friction torque, parameter variations of plant and environment and so on, the reaction torque control system is constructed with a disturbance observer which estimates the disturbances based on the reference input to the inner torque control system and the reaction torque sensed with a forced sensor. From some simulations and experiments, it is confirmed that the proposed control system is effective to improve the robustness for the friction torque and the parameter change of object in the force control of a pneumatic robot manupulator.

Development of Sintered Oilless Bearing using Fluid-Dynamic Mechanism For High-RPM Application (유체동압 메카니즘을 이용한 고RPM용 소결함유베어링의 개발)

  • 최윤철
    • Journal of Powder Materials
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    • v.4 no.4
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    • pp.275-282
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    • 1997
  • Sintered oilless bearing using fluid-dynamic mechanism for high revolution of over 10,000 rpm was developed by Powder metallurgy Process. Developed bearing was composed of Fe-40-60%Cu of which inner face consisted of six-regular-prominence-and-depression. Inner face has controlled pore size and amount according to application. Jitter and friction properties were tested under assembled conditions with housing and motor. Bearing-own properties and precision were also tested because of demanding for assembled properties. Measurement-skill as well as mould-production-skill were investigated for the precision of bearing. Final precision reached 2 ${\mu}m$ in inner diameter tolerance and 5 ${\mu}m$ in coaxiality under assembled conditions.

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A Study on Pressure Vessel using Cold Stretch Method (냉연신 공법을 이용한 압력용기의 제조에 관한 연구)

  • Han, Kyu-Taek
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.17 no.1
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    • pp.153-160
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    • 2018
  • A pressure vessel consists of an inner tank and the outer tank; the material of the inner tank is austenite stainless steel, and the outer tank is general carbon steel. As the storage amount increase, the size of the inner tank for LNG also increases, which eventually increases the weight of the LNG storage tank. The Cold Stretch method can transport and store the LNG in a larger amount than the conventional pressure container, and the weight of the pressure vessel can also be reduced at 50 70% due to the reduction of the thickness, which is excellent from an economic and energy consumption perspective. Although the Cold Stretch method has these advantages, the domestic situation has not developed any related legislation. In this study, the actual production of pressure vessels using the Cold Stretch method will be processed and the volume expansion after the Cold Stretch will be checked and compared with the mechanical properties.

Camera Exterior Parameters Based on Vector Inner Product Application: Exterior Calibration of a Camera and a Range Finder (벡터내적 기반 카메라 외부 파라메터 응용: 카메라와 레이져스캐너간의 캘리브레이션)

  • Chon, Jae-Choon;Sastry, Shankar
    • Korean Journal of Remote Sensing
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    • v.23 no.6
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    • pp.553-558
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    • 2007
  • The equation based on vector inner product by the angles between pairs of two image rays can independently separate the position and pose of a camera. As our second application, the exterior calibration between a camera and a laser range finder is proposed here through analysis of surfaces created by the equation.

Effect of Dietary Structural to Nonstructural Carbohydrate Ratio on Rumen Degradability and Digestibility of Fiber Fractions of Wheat Straw in Sheep

  • Tan, Z.-L.;Lu, D.-X.;Hu, M.;Niu, W.-Y.;Han, C.-Y.;Ren, X.-P.;Na, R.;Lin, S.-L.
    • Asian-Australasian Journal of Animal Sciences
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    • v.15 no.11
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    • pp.1591-1598
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    • 2002
  • The effect of different dietary structural carbohydrate (SC) to nonstructural carbohydrate (NSC) ratios on fiber degradation, digestion, flow, apparent digestibility and rumen fluid characteristics was studied with a design using 18 wethers fitted with permanent rumen and duodenum cannulae. All sheep were divided into six groups randomly, receiving six diets with varying SC to NSC ratios. All diets contained the same proportion of wheat straw and concentrate. The dietary SC to NSC ratios were adjusted by adding cornstarch to the concentrate supplements. The duodenal and fecal flows of dry matter (DM), neutral detergent fiber (NDF), acid detergent fiber (ADF), hemicellulose (HC) and cellulose (CEL) were estimated using chromium-mordanted wheat straw as a flow marker. The degradation parameters of wheat straw DM, NDF, ADF, HC and CEL were determined by incubating the ground wheat straw in nylon bags in the rumen for different periods of time. There was no effect (p>0.05) of the different dietary SC to NSC ratios on rumen pH or $NH_3$-N, but acetate, propionate and butyrate concentrations were significantly affected (p<0.05 or p<0.01) by dietary SC to NSC ratios in the rumen fluid. When the dietary SC to NSC ratio was 2.86, the highest rumen degradability of wheat straw DM, NDF, ADF and CEL was found, but the highest apparent rumen digestibilities of DM, NDF, ADF, HC and CEL occurred at a 2.64 SC to NSC ratio. However, because of compensatory digestion in the hindgut, the apparent digestibilities of DM, NDF, ADF, HC and CEL were highest when the dietary SC to NSC ratio was 2.40. In conclusion, there is a optimal range of dietary SC to NSC ratios (between 2.86 and 2.40) that is beneficial to maximize wheat straw fiber degradation and apparent digestibility.

Effects of Dietary Nitrogen Sources on Fiber Digestion and Ruminal Fluid Characteristics in Sheep Fed Wheat Straw

  • Tan, Z.-L.;Lu, D.-X.;Hu, M.;Niu, W.-Y.;Han, C.-Y.;Ren, X.-P.;Na, R.;Lin, S.-L.
    • Asian-Australasian Journal of Animal Sciences
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    • v.14 no.10
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    • pp.1374-1382
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    • 2001
  • Fifteen Inner Mongolian wethers with permanent ruminal and duodenal cannulas were used to study the effects of dietary rumen-undegradable protein (RUP) to rumen-degradable protein (RDP) ratios or protein sources on fiber digestion in the gastrointestinal tract and ruminal fluid characteristics. Fiber digestion and ruminal fermentation were not affected (p>0.05) by dietary RUP to RDP ratios (from 1.54 to 0.72). Soybean meal supplementation improved ruminal digestion. Fish meal supplementation increased (p<0.05) the ruminal degradability of fiber. The different RUP to RDP ratios (from 1.54 to 0.72) did not influence (p>0.05) ruminal fluid pH, but there were differences (p<0.05) in ruminal fluid $NH_3-N$ concentration because of urea replacement. Soybean meal as a dietary protein source decreased (p<0.05) ruminal fluid pH and increased (p<0.05 or p<0.01) $NH_3-N$, acetate, propionate and butyrate concentrations in the rumen. Fish meal as a dietary protein source decreased (p<0.05 or p<0.01) ruminal $NH_3-N$ and acetate concentrations and increased (p<0.05) ruminal propionate concentration. It can be concluded that dietary protein sources have more significant effect on fiber digestion and ruminal fermentation than different dietary RUP to RDP ratios, when the dietary crude protein requirements of growing sheep are satisfied.