• 제목/요약/키워드: inner filter effect

검색결과 22건 처리시간 0.027초

사람 대동맥 평활근 세포에서 이묘산(二妙散)의 항동맥경화 활성 (Anti-atherosclerosis Effect of Imyosan Extract in Human Aortic Smooth Muscle Cells)

  • 윤현정;허숙경;이효승;김태훈;김동완;김선모;박선동
    • 대한본초학회지
    • /
    • 제23권4호
    • /
    • pp.113-120
    • /
    • 2008
  • Objectives: This study was evaluated to elucidate the inhibitory potential of Imyosan(IMS) and its components, Phellodendri Cortex(PC: Phellodendron amurense Rupr., Hwangbaek in Korean) and Atractylodis Rhizoma(AR: Atratylodes lancea D.C., Changchool in Korean), on human aortic smooth muscle cells(HASMC) migration and production of matrix metalloproteinase (MMP)-2 and MMP-9 by TNF-${\alpha}$ treatment. Methods: Cytotoxic activity of IMS and its components on HASMC was using 5-(3-caroboxy meth-oxyphenyl)-2H-tetra-zolium inner salt(MTS) assay. Effect of IMS, PC and AR on TNF-${\alpha}$-induced HASMC migration underside of matrigel filter was stained with hematoxylin-eosin. And total number of cells that migrated to the underside of the filter was counted. MMP-2 and MMP-9 activity was evaluated by gelatin zymography assay. Results: The matrigel migration assay showed that IMS effectively inhibited the TNF-${\alpha}$-induced migration of HASMC. Moreover, IMS significantly inhibited MMP-9 activity. Our present study demonstrates that IMS and its components inhibit TNF-${\alpha}$-induced HASMC migration and MMP-9 activity. The inhibitory effect of IMS extract is more potent than that of its component herb extracts. Conclusions: These results provide evidence that IMS has multiple effects in the inhibition of HASMC migration and may offer a therapeutic approach to block HASMC migration.

  • PDF

보두산의 금속분해효소 활성 저해를 통한 사람 대동맥 평활근세포의 유주능 억제 효과 (Inhibitory Effect of Bodusan on $TNF-{\alpha}-induced$ Migration via Inhibition of Metalloproteinase Activity in Human Aortic Smooth Muscle Cells)

  • 윤현정;박선동
    • 대한본초학회지
    • /
    • 제23권3호
    • /
    • pp.155-162
    • /
    • 2008
  • Objectives : This study was evaluated to elucidate the inhibitory potential of Bodusan (BDS) and its components, Strychnos ignatii semen (SIS) and Glycyrrhizae Radix (GR), on human aortic smooth muscle cells (HASMC) migration and production of matrix metalloproteinase (MMP)-2 and MMP-9 by $TNF-{\alpha}$ treatment. Methods : Cytotoxic activity of BDS and its components on HASMC was using 5-(3-caroboxymeth- oxyphenyl)-2H-tetra-zolium inner salt (MTS) assay. Effect of BDS, SIS and GR on $TNF-{\alpha}-induced$ HASMC migration underside of matrigel filter was stained with hematoxylin-eosin. And total number of cells that migrated to the underside of the filter was counted. MMP-2 and MMP-9 activity was evaluated by gelatin zymography assay. Results : The matrigel migration assay showed that BDS effectively inhibited the $TNF-{\alpha}-induced$ migration of HASMC. Moreover, BDS significantly inhibited MMP-9 activity. Our present study demonstrates that BDS and its components inhibits $TNF-{\alpha}-induced$ HASMC migration and MMP-9 activity. The inhibitory effect of BDS extract is more potent than that of its component herb extracts. Conclusions : These results provide evidence that BDS has multiple effects in the inhibition of HASMC migration and may offer a therapeutic approach to block HASMC migration.

  • PDF

스월 인젝터의 음향학적 감쇄기로서의 백홀에 대한 연구 (Backhole as an Acoustic Damper for the Swirl Injector)

  • 황성하;윤영빈
    • 한국추진공학회:학술대회논문집
    • /
    • 한국추진공학회 2003년도 제21회 추계학술대회 논문집
    • /
    • pp.153-156
    • /
    • 2003
  • 스월 인젝터의 분무특성을 변화시키는 기하학적인 변수인 백홀은 스월 인젝터의 내부유동이나 음향학적인 특성에도 큰 영향을 주게 된다. 백홀이 연소불안정 제거를 위하여 연소실에 부가적으로 부착하는 음향공(Acoustic cavity)과 유사한 역할을 할 수 있는지 알아보기 위하여 백홀을 Helmholtz resonator나 Quarter-wave resonator로 해석하였다. 그 결과 백홀을 가지는 스월 인젝터는 연소실내의 파동과 상쇄될 수 있는 고유주파수를 가지게 될 수 있었다. 또한 이를 위한 설계식을 제시하였다.

  • PDF

대표영상을 이용한 나무구조의 한글문자 인식 (Korean Character Recognition with Tree Structure Using Representative Images)

  • 김정우;정수길;조웅호;김성용;김수중
    • 전자공학회논문지B
    • /
    • 제31B권4호
    • /
    • pp.18-29
    • /
    • 1994
  • For the efficient recognition of Korean Alphabets, we proposed the tree structure algorithm which was based on K-tuple NRF-SDF using representative images as training images. Representative images consisted of ECP-SDF images of several consonants or vowels. To reduce the effect of sidelobe in the output correlation plane, we used the representative images as training images and obtained the elements of a vector inner product matrix using the peak value of AMPOF correlation of training images with one another. The proposed algorithm consisted of three main-step containing several substeps. In filter synthesis of each step, representative images were used as training images in the first and the second main-step and each consonant or vowel was used as training images in the third main-step. The performance of this algorithm is demonstrated by computer simulation and optical experiment.

  • PDF

동적 윤곽선 모델을 이용한 PC 카메라 영상에서의 얼굴 윤곽선 추출 (Facial Contour Extraction in PC Camera Images using Active Contour Models)

  • 김영원;전병환
    • 한국콘텐츠학회:학술대회논문집
    • /
    • 한국콘텐츠학회 2005년도 추계 종합학술대회 논문집
    • /
    • pp.633-638
    • /
    • 2005
  • 얼굴 추출은 휴먼 인터페이스와 생체 인식 및 보안을 위해 매우 중요한 분야이다. 본 논문에서는 동영상에서 얼굴의 윤곽선을 추출하기 위해, DCM(Dilation of Color and Motion)필터와 동적 윤곽선 모델(Active Contour Model) 적용한다. 먼저, 본 논문에서 제안된 DCM 필터는 모폴로지의 팽창 연산이 적용된 얼굴 색상영상과 차영상을 결합하고 이를 다시 팽창한 것으로 동영상에서 복잡한 배경을 제거하고 얼굴 영역을 검출하기 위해 사용된다. 동적 윤곽선 모델은 초기 곡선에 영향을 많이 받으므로, 얼굴과 눈, 입의 기하학적인 비율을 이용하여 회전정도를 구한 후, 이를 이용하여 초기 곡선을 자동으로 설정한다. 에지가 약한 부분에서의 윤곽선 추출을 위해, 스네이크의 영상에너지로 에지영상과 밝기영상을 함께 사용하였다. 복잡한 배경이 있는 실내 환경에서 총 5명으로부터 양 눈이 보이는 다양한 헤드 포즈 영상을 25장씩 샘플링하여 총 125장에 대해 실험한 결과, 얼굴 윤곽선의 평균 추출률은 98.1%, 평균 처리시간은 0.2초로 나타났다.

  • PDF

의료용 전동공기청정호흡기(PAPR)용 항균성 후드 및 필터 개발 (Development of Antibacterial Hood and Filter for Medical Powered Air Purifying Respirators (PAPR))

  • 고은주;조나현;이용택
    • 멤브레인
    • /
    • 제33권6호
    • /
    • pp.398-408
    • /
    • 2023
  • 본 연구는 지카바이러스, 메르스, coronavirus disease-19 (COVID-19) 등의 감염병 방역 및 의료현장에서 사용할 수 있는 의료용 공기정화호흡기(powered air purifying respirators, PAPR)의 항균성 보호복의 후드와 필터를 개발하였다. PAPR은 전동팬 본체 및 필터, 배터리팩, 후드로 구성되며 보호복의 후드 소재는 뛰어난 흡습성, 풍압, 외부충격을 견딜 수 있는 폴리프로필렌 슐폰레이스(spunlace) 부직포 직물(SFS)을 사용하였다. 사용자의 감염위험을 낮추기 위해 후드의 외피에는 피톤치드계 물질을 사용하여 99.9%의 안티-박테리얼(antibacterial) 효과를 얻었으며 내피에는 친수가공을 하여 흡수성을 25% 향상시켰다. 의료용 보호복 후드에 필요한 인공혈액 침투저항성, 건조미생물 침투저항성, 습식세균 침투저항성, 그리고 박테리오파아지 침투저항성을 평가한 결과 2~6 단계의 합격평가를 받았다. 한편, 항균 처리된 슐폰레이스(spunlace filter, SF) 헤파 필터(high efficiency particulate air, HEPA)의 성능을 평가한 결과 우수한 항균성, 분진제거율, 차압 효과를 확인하였다.

메탄/공기 층류 부분 예혼합화염에서 예혼합 정도에 따른 화염구조와 질소산화물의 배출에 미치는 영향에 관한 연구 (The Study of Effects of Variable Parameters on Flame Structure and NOx Emission in Methane/Air Laminar Partially Premixed Flames)

  • 오정석;정용기;전충환;장영준
    • 대한기계학회:학술대회논문집
    • /
    • 대한기계학회 2003년도 추계학술대회
    • /
    • pp.362-367
    • /
    • 2003
  • It is shown that the effect of variable parameters on flame structures and NOx emissions in the laminar partially premixed methane-air flames with a co-axial Bunsen burner. Objectives of this paper is to understand the effects of flow variables on NOx emissions and the flame structure with OH chemiluminescence, including reconstructed image by abel inversion processing at each conditions. A fuel flowrate of 200 [cc/min] was fixed and the amount of air was varied from 400 to 1200 [cc/min]. The experimental variables were equivalence ratio(${\Phi}$ fuel split percentage(${\sigma}$ and inner tube recess(x/D). Flow conditions were ranged from $1.36{\sim}4.76$(equivalence ratio), $50{\sim}100$(fuel split percentage) and $0{\sim}20$(inner tube recess). NOx analyzer and ICCD camera with a OH filter were used as a main experimental apparatus. In addition, Abel inversion, which is a kind of tomography and valuable to estimate a two-dimensional structure of co-axial flames from cubical information, was employed for combustion diagnostics. Results from this study indicate that the main effects depend on equivalence ratio and next sigma, x/D for NOx production and OH formation. Throughout Abel inversion, we could affirm the maximum position and the tendency of OH radical intensity by variants at five axial heights above the burner exit.

  • PDF

그래뉼 타입 활성탄 필터의 100 나노 미만 다분산 초미세먼지 표면흡착 제거 효율 연구 (Filtration Efficiency of Granular Activated Carbons to Polydisperse Ultrafine Particles through the Surface Adsoprtion)

  • 조경일;강기원;신지윤;김창혁
    • 한국입자에어로졸학회지
    • /
    • 제18권3호
    • /
    • pp.79-86
    • /
    • 2022
  • Many commercial air purifiers currently have deployed granular activated carbon (GAC) filters for removing volatile organic compounds in the indoor air. GACs are generally used to remove gaseous contaminants in the air through adsorption by the inner surfaces of pores. In addition, airborne particles can be also filtered by the surface adsorption of the GACs, which can improve the life-time of the particulate filters. In this study, the filtration efficiency of GACs to ultrafine particles through surface adsorption was investigated at different volume flow rates by deploying a continuous particle filtration system. The polydisperse sodium chloride (NaCl) particles were generated by a set of an atomizer and a diffusion dryer, and then mixed with particle-free air at different volume flow rates. The penetration of ultrafine particles and pressure drop for each experimental condition were measured to figure out the effect of the volume flow rate on the surface adsoprtion of the GACs to particles, ~ 2 mm. The particle filtration efficiency of the GACs decreased as the volume flow rate increased from 4 to 14 lpm. However, the 5 times thicker GAC filter layer decreased the penetration of ultraparticles than a preious study. The filtration efficiency of the single granule was also higher than the previous result in the literature with smaller granule filter materials.

Fluorescence-Quenched Sensor for Trinitophenol in Aqueous Solution Based on Sulfur Doped Graphitic Carbon Nitride

  • Min, Kyeong Su;Manivannan, Ramalingam;Satheshkumar, Angu;Son, Young-A
    • 한국염색가공학회지
    • /
    • 제30권2호
    • /
    • pp.63-69
    • /
    • 2018
  • In this study, we report on successful attempt towards the synthesis of sulfur self-doped $g-C_3N_4$ by directly heating thiourea in air. The synthesized materials were characterized using UV-vis spectral technique, FT-IR, XRD and TEM analysis. Further, the obtained material shows an excellent detection of carcinogenic TNP(Tri nitro phenol) in the presence of 10-fold excess of various other common interferences. The strong inner filter effect and molecular interactions(electrostatic, ${\pi}-{\pi}$, and hydrogen bonding interactions) between TNP and the $S-g-C_3N_4$ Nano sheets led to the fluorescence quenching of the $S-g-C_3N_4$ Nano sheets with an excellent selectivity and sensitivity towards TNP compared to that of other nitro aromatics under optimal conditions and the detection limit calculated was found to be 6.324 nM for TNP. The synthesized nanocomposite provides a promising platform for the development of sensors with improved reproducibility and stability for ultra-sensitive and selective sensing of TNP.

저항패션이 모패션으로 전이된 현상에 관한 연구 -히피풍을 중심으로- (study on the Transfeal Phenomenon of Anti-fashion into Mother-fashion -In the Case of Hippie Look-)

  • 박명희
    • 복식
    • /
    • 제28권
    • /
    • pp.239-253
    • /
    • 1996
  • The purpose of this dissertation is to exam-ine the hippie look which is one of the most popular fashion trends in the early 90s, in re-lation to the hippie style in 60s and cultural restoration. in order to investigate the re-lationship this dissertation studies the trans-feral phenomenon of anti-fashion into mother fashion in the basis of social and clutural theories. hippie culture is the anti-culture which appeared in America in the late 60s, it tried to create a new culture by subverting the ruling class culture with their combative life style and peculiar appearance which are distinguished from mother culture. First of all to examine the inner symbolic meaning and outer shape of the hippie style I divided the characteristics of the hippies into ideology social value and attitude on sex. in the aspect of ideology the hippie show strong subjectivity while mother culture shows ob-jectivity. in social value the hippie has the resisting chaacteristics while mother culture has the conformative characteristics. In the aspect of sex the hippie tries to break the fixed idea of mother culture. Hippie culture as anti-culture is symbolically expressed in hippie style fashion which is dif-ferent from mother fashion in shape. There-fore the inner meaning and the outer shape of the hippie style shows strong characteristics of anti-fashion. Hippie style as anti-fashion has an effect on high fashion in the late 60s and the early 70s and on hippie look which is restored in 90s. however hippie-look in 90s is a mother-fashion in which all symbolic mean-ings of the hippie style are weakened and the only outer shape of hippie style is presented and suggested. It doesn't show any cultural backgrounds ideology social value and new attitude on sex of the hippies. The transferal phenomenon of anti-fashion into mother-fashion is summarized as follows. First in the process of tranference to highfashion in 60s and 70s and hippie-look in 90s the resistance of the hippie style is weakened and only suggested through the outer look. Second the hippie style which reappeared in the high fashion and mother fashion in 90s are layered look military uniform mode flower print grunge look romantic look peasant look ethnic look gypsy style handicraft ornaments working suit style handicraft ornaments working suit style and the use of the see-through cloth. Third the fact that the popular and high fashion were influenced by anti fashion in 60s proves filter-up theory in fashion adaption theory. As I examined before the ideology of the hippies are faded in high fashion in 60s-70s and hippie-look in 90s. The symbolic meaning of the hippie style is also weakened and only presented as a fashion trend.

  • PDF