• Title/Summary/Keyword: injection duration

Search Result 477, Processing Time 0.027 seconds

Neuropathic Pain Management with NMDA Receptor Antagonist (Ketamine) in Pain Clinic -A case report- (NMDA 수용체의 길항제인 Ketamine를 이용한 신경병증성 통증 치료)

  • Ahn, Mi-Jung;Kim, Hae-Ja;Lee, Won-Hyung;Shin, Yong-Sup;Lee, Jung-Un
    • The Korean Journal of Pain
    • /
    • v.11 no.2
    • /
    • pp.294-298
    • /
    • 1998
  • The feature of neuropathic pain may occur in the absence of any apparent stimulus and be exaggerated in either amplitude or duration. Peripheral nerve injury may produce neuropathic pain and opioids have been shown to be relatively unsatisfactory for the treatment of most cases of neuropathic pain. The NMDA receptor system is involved in transmission and modulation of nociceptive information. We treated patients with severe pain, hyperaesthesia and allodynia with epidural injection of NMDA receptor antagonist, ketamine (10 mg) and morphine (0.5 mg) or other opioid. The combinations provided effective pain management in 23 patients with neuropathic pain.

  • PDF

The Clinical Study of Ketamine HC1 on Oral Surgery (구강외과 영역에 있어서 Ketamine HC1의 임상적 고찰)

  • Cho, Byoung-Uk
    • The Journal of the Korean dental association
    • /
    • v.11 no.1
    • /
    • pp.45-52
    • /
    • 1973
  • Ketamine HC1(Phencyclidine derivative) is a white, crystalline substance with melting point 259℃. It is soluble in water to a 20% clear, colorless solution. a 10% aqueous solution has a pH 3.5. The chemical structure is 2-(O-chlorophenyl)-2-(methylamino) cyclohexanone hydrochloride. It is a rapid acting, nonhypnotic, nonbarbiturate drug with a wide safety margin. The author used the anesthetic ketamine hydrochloride for oral surgery procedure in 16 patients(2 to 33 years). Anesthesia was achieved with a single intramuscular injection by introduction of manufacture. Result obtained as follows : 1. It was easily administered. 2. Onset time was rapid and duration was short. 3. The mild cardiac stimulation resulted in moderate increase in the blood pressure and pulse. 4. There was no significant respiratory depression. 5. The airway can be maintained without artificial support or endotracheal intubation. 6. All protective reflex maintained, which was important in oral surgery. 7. The best results were achieved in pediatric patients than adults.

  • PDF

The excimer laser ablation of PET for nickel electroforming (니켈 전주도금을 위한 PET의 엑시머 레이저 어블레이션)

  • Shin, Dong-Sik;Lee, Je-Hoon;Seo, Jung;Kim, Do-Hoon
    • Laser Solutions
    • /
    • v.6 no.2
    • /
    • pp.35-41
    • /
    • 2003
  • In this study, manufacturing of polymer master and mold insert for micro injection molding was investigated. Ablation by excimer laser radiation could be used successfully to make 3-D microstructure of PET. The mechanism for ablative decomposition of PET with KrF excimer laser(λ: 248nm, pulse duration: 5ns) was explained by photochemical process. And this process showed PET to be adopted in polymer master for nickel mold insert. Nickel electroforming by using laser ablated PET master was preferable for replication method. Finally, it was shown that excimer laser ablation can substitute for X-ray lithography of LIGA process in microstructuring.

  • PDF

A study on deformation and strength of polymer composites using automobiles (자동차용 폴리머 복합재료의 변형과 강도에 관한 연구)

  • Shin, Je-Hoon;Lim, Jae-Kyoo;Park, Han-Ju
    • Proceedings of the KSME Conference
    • /
    • 2000.11a
    • /
    • pp.238-243
    • /
    • 2000
  • The effect of the temperature, the fatigue and the test speed on DEN(double edged notch) specimen which was made by the pp-rubber composites during fracture was stuied. DEN specimen was made on PP-rubber composites through the injection molding. With increasing temperature the fracture strength is linearly decrease and the fracture energy is first increase by $0^{\circ}C$ and after that decrease. In the same temperature the fracture strength during increasing the notch radius is hardly increase. The fracture behaviour at low and high test speed is different entirely. At high test speed plastic region is small and fracture behaviour was seen to brittle fracture tendency. The deformation mechanism of polypropylene-rubber composites during fracture was studied by SEM fractography. A strong plastic deformation of the matrix material ahead of the notch/crack occured. The deformation seem to be enhanced by a thermal blunting of the notch/crack.

  • PDF

Observations on the Near-Nozzle Behavior of an Unsteady Fuel Spray (노즐부근에서의 비정상분무 거동)

  • 구자예;정흥철
    • Transactions of the Korean Society of Automotive Engineers
    • /
    • v.2 no.4
    • /
    • pp.100-111
    • /
    • 1994
  • Observations on the near-nozzle behavior of an unsteady fuel spray through single cylindrical hole nozzle were made by phase Doopler anemometer and microphotographs. At the edge of the spray, droplet velocity peaked during needle opening and closing. Droplet sizes tended to be small on the edge of spray. The near-nozzle spray angle taken from the microphotographs was time-dependent, even though it increased with gas-to-liquid density ratio as expected. The near-nozzle spray angle was the greatest on the initial stage and decreased to a relatively constant value after about one third of the total injection duration regardless of the ambient gas conditions, even in the near-vaccum condition. The wider near-nozzle spray angle in the early stage is due to the flow characteristics inside the nozzle rather than aerodynamic interactions. However, once the spray was established, aerodynamic interactions are essential in the near-nozzle atomization.

  • PDF

Studies on Effects of the Administration of $PGF_{2\alpha}$ GTH and Antibiotics in Repeat Breeders (Prostaglandin $F_{2\alpha}$, GTH 및 Antibiotics의 투여가 Repeat breeder의 치료에 미치는 영향)

  • 정병현
    • Korean Journal of Animal Reproduction
    • /
    • v.9 no.1
    • /
    • pp.66-71
    • /
    • 1985
  • After the induction of estrus by the PGFF2$\alpha$-GTH combination on the 118 repeat breeder cow during of 6-13 days of the estrus cycle, the effects of GTH, antibiotics, antibiotics-GTH combination were compared. The results of this study, the following conclusion were obtained: 1. The rate of estrus was reduced the administration of GTH before the administration of PGF2$\alpha$. 2. The rate of ovulation delayed was 24.6% in the group with the administration GTH, but 34.1% without the administration GTH. Duration of ovulation was shortened by GTH. 3. The impregnation induction by the administration of PGF2$\alpha$, PGF2$\alpha$-antibiotics, PGF2$\alpha$-GTH-antibiotics were 41.7%, 69.5%, 55.6% and 80.8% respectively injection in the uterus was more effective than the administration. Before or after the A.I., the above combination was most effective. 4. In antibiotics sensitivity test in vitro of the intravagina bacteria, 5.0%, 12.7% and 60.0% of bacteria were sensitive to Penicilline, Streptomycin and Gentamicin respectively.

  • PDF

The Experimental Study on the Low-temperature Combustion Characteristics of DME Fuel in a Compression Ignition Engine

  • Yoon, Seung Hyun
    • Journal of ILASS-Korea
    • /
    • v.22 no.4
    • /
    • pp.190-196
    • /
    • 2017
  • The aim of this work is to investigate the combustion and exhaust emission characteristics of low-temperature combustion (LTC) at various EGR test conditions using a single cylinder common-rail diesel engine. In high EGR rate combustion mode with DME fuel, 30% (${\Phi}=0.61$) and 50% (${\Phi}=0.86$) of EGR were respectively examined, and then the combustion, exhaust emissions, nano-particle characteristics of each cases were measured. From these results, it revealed that The ignition delay and combustion duration are prolonged as the increase of EGR rate. In addition, at an advanced injection timing (BTDC $30^{\circ}$), ignition delays were fairly increased because the dilution effect of EGR and also low charge in-cylinder temperature created a lean mixture, thus decreased the peak release rate.

A Thermal hydraulic Investigation on ADSR Liquid Lead Target

  • Kim, Ju Y.;Byung G. Huh;Chang H, Chung;Tae Y. song;Park, Won S.
    • Proceedings of the Korean Nuclear Society Conference
    • /
    • 1998.05a
    • /
    • pp.666-671
    • /
    • 1998
  • Computational fluid dynamics(CFD) code FLUENT[11 was used to simulate the thermal hydraulic processes occuring in conceptual design of the accelerator-driven subcritical reactor(ADSR) liquid lead target. The purpose of the analysis is to investigate the thermal hydraulic characteristics of liquid lead as ADSR target material with various target geometries and injection locations of proton beam. In the calculation analysis, the local temperature of the liquid lead target rises to the boiling temperature very rapidly When the proton beam is injected from the bottom of the target system, the duration time to reach the boiling temperature is longer and the temperature distribution is flatter than other cases.

  • PDF

Betatron Radiation of an Off-axis Injected Electron in a Laser Wakefield Accelerator

  • Hwang, Seok-Won;Lee, Hae-June
    • Journal of the Optical Society of Korea
    • /
    • v.13 no.1
    • /
    • pp.86-91
    • /
    • 2009
  • The electrons injected into a laser wakefield undergo betatron oscillation and give rise to the emission of intense X-ray radiation. To investigate the generation conditions of the X-rays, the relativistic motion of an electron injected in an off-axis position has been simulated with wakefield profiles which are pre-calculated with a two-dimensional particle-in-cell code. The wakefield with a plasma density of $1.78{\times}10^{18}\;cm^{-3}$ is generated by the laser with an intensity of $1.37{\times}10^{18}\;W/cm^2$ and a pulse width of 30 fs. From the calculation of the single particle motion, the characteristics of the betatron radiation are investigated in the time domain. As the transverse injection position increases, the power and the duration time of the radiation increase, but the width of each pulse decreases.

Combustion Characteristics of Methane-Air Mixture in a Constant Volume Combustion Chamber(2) : Inhomogeneous Charge (정적연소기에서의 메탄-공기 혼합기의 연소특성(2) : 비균질급기)

  • 최승환;전충환;장영준
    • Transactions of the Korean Society of Automotive Engineers
    • /
    • v.11 no.4
    • /
    • pp.29-36
    • /
    • 2003
  • A cylindrical constant volume combustion chamber was used to investigate the flow characteristics at spark plug and the combustion characteristics of inhomogeneous charge methane-air mixture under several parameters. The flow characteristics such as mean velocity and turbulence intensity was analyzed by hot wire anemometer. Combustion pressure development measured by piezoelectric pressure transducer was used to investigate the effect of initial charge pressure, excess air ratio and ignition times on combustion pressure and combustion duration. Mean velocity and turbulence intensity had the maximum value at 200 or 300ms and then decreased to beneath 0.05m/s gradually at 3 seconds. Second mixture is accompanied by an increase in the combustion rate, and that the higher the mass which is added in the second stage injection, the faster the burn rate.