• 한국안전학회지
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• 제5권3호
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• pp.3-7
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• 1990

This study is conducted to experiment on the performance test for 20 types of Filter-integrated Half-masks which could not only protect workers exposed to dusty environment, but also improve workability. Results and conclusions are as follows ： 1) Respirators that removal efficiency of aerosols is 95 percent or more are 11 kinds(55%), and those who are 99.9 percent or more are 4 kinds(20%). Respirators that inhalation resistance is 4 mm in water or less are 13 kinds(65%), and those who are 6 mm in water or less are 17 kinds(85%). Respirators that efficiency of cumulative inhalation resistance is 100 percent or less are 11 kinds(55%) . 2) Respirators that resistance of moisture inhalation is 6 mm in water or less are 11 kinds(55%). and those who are 10 mm in water or less are 13 kinds(65cio), Respira'tors that ratio of removal efficiency for aerosols between dry and wet conditions is 95 percent or more are 9 kinds(45%). 3) Respirators which are not only 95 percent or more for removal efficiency of aersosls and 6 mm in water or less for inhalation resistance, but also 200 percent or less for efficiency of cumulative inhalation resistance, are 8 kinds(40％). Respirators which are not only 99.9 percent or more for removal efficiency and 6 mm in water or less for inhalation resistance, but also 100 percent or less for efficiency of cumulative inhalation resistance, are 3 kinds(15%). Respirators which are not only 95 percent or more for removal efficiency of aerosols and 6 mm in water or less for inhalation resistance, but also 200 percent or less for efficiency of cumulative inhalation resistance and 10 mm in water or less for resistance of moisture inhalation, are 6 kinds(30％) . 4) As standard rrlodel of artificial human head which would be perhaps different from the true one Is used to experiment fitness test, leakage rate is shown to be more or less high. However, artificial human head shall be accurately examined and follow-up studt. would be conducted in the future.

• 한국환경보건학회지
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• 제46권1호
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• pp.78-87
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• 2020

Objectives: To identify the degree of physical burden, a determination was undertaken of dust collection efficiency, inhalation pressure, and CO₂ concentration related to health masks certified by the Ministry of Food and Drug Safety (MFDS). Methods: Twenty health masks were purchased on the market. Dust collection efficiency and inhalation pressure were determined in the same manner as in MFDS certification testing, respectively using TSI Model 8130 (TSI, U.S.) and ART Plus (Korea). CO₂ concentrations for 20 subjects using a CO₂ analyzer (G100, G150, Geotechnical Instrument Ltd., UK) were measured with a similar method as a total inward leakage test. In addition to CO₂ levels, dead space volumes in the masks was determined for predicting concentrations of CO₂ in inhalation air. Results: Most of the dust collection efficiencies found for the 20 masks were far higher than the standard. Four KF94s met KF99 and four KF80s even met KF94. Most inhalation pressures were also much lower than the standard, with many almost one-half of the standard. The mean and standard deviation of CO₂ concentration in the mask were 2.9±0.44%. Considering dead volume, the prediction for CO₂ concentration in the inhalation air was 4,395±1,266 ppm. Conclusions: For healthy men and women, the dust collection efficiency and inhalation pressure of health masks were not at a level that would affect their health. Although CO₂ levels in the inhalation air were predicted not to affect health, research on the physiological effects of health masks on Koreans is needed for more precise research.

• 한국환경보건학회지
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• 제47권3호
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• pp.292-301
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• 2021

Objectives: Wearing medical masks has been recommended since the declaration of coronavirus disease-19 (COVID-19) as a pandemic disease. Certified medical masks are evaluated according to filtration efficiency and facial inhalation resistance. However, some people use non-certified common masks. This study aimed to evaluate various non-certified commercial masks based on the certification criteria for medical masks. Methods: Twenty mask products (three anti-droplet, three disposable dental, eight fashion, three cotton, and three children's masks) were selected. For performance evaluation, filtration efficiency and facial inhalation resistance tests were conducted. The evaluation method followed the certification method for KF-certified masks of the Ministry of Food and Drug Safety (MFDS) and the N95 respirator of the National Institute for Occupational Safety and Health (NIOSH). Results: None of the 20 masks met the KF94 certification standard set by the MFDS. Four and three masks respectively met the KF80 certification standard and the N95 standard of NIOSH. Filtration efficiency was significantly higher in three-layer masks than in single layer masks. Pleated-type masks had higher filtration efficiency than cone-type masks. There was no correlation between the structure of masks and facial inhalation resistance. Conclusion: While no masks complied with the KF94 certification standard, a few masks met the KF80 and the N95 certification standards of NIOSH. Although some people wear non-certified commercial masks, protection from aerosols is not guaranteed by such masks. Evaluation of the protection efficiency of non-certified mask against microbiological infection is needed for the prevention of infectious disease.

• 한국안전학회지
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• 제23권2호
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• pp.1-6
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• 2008

The present study investigates on improvement of inhalation efficiency of hood in ventilation system for elimination of industrial dust. The hood, one of local exhaust ventilation system, has an important function to inhale a pollution source such as harmful dust and industrial waste. In this study, in order to improve the inhalation efficiency of the industrial hood, a new device named "gas-guide-device" was attached to inside of hood. The thermal fluid commercial code "Phoenics ver 3.1" was used to analyze the flow velocity distribution at the hood inlet and around the hood after gas-guide-device was installed. And the flow velocity on each position inside and around the hood was actually measured using the hot wire type anemometer under the same condition as that of numerical analysis. Also, in order to identify the optimum shape of gas-guide-device, numerical analysis and experiments are performed under various conditions and their results are presented. The results of this study revealed that the hood attached with gas-guide-device was higher the inhalation efficiency than that for without one and can be possible to improve the capture velocity of the industrial dust. And the optimum shape of gas-guide-device was identified that the ratio of two sizes of gas-guide-device, X to Y, has 4 to 6 on the basis of the hood size in use and the width (b) of gas-guide-device.

• 한국환경보건학회지
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• 제48권3호
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• pp.151-158
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• 2022

Background: Chemical emissions in the environment have rapidly increased with the accelerated industrialization taking place in recent decades. Residents of industrial complexes are concerned about the health risks posed by chemical exposure. Objectives: This study was performed to suggest modeling methods that take into account multimedia and multi-pathways in human exposure and risk assessment. Methods: The concentration of benzene emitted at industrial complexes in Daesan, South Korea and the exposure of local residents was estimated using the Caltox model. The amount of human exposure based on inhalation rate was stochastically predicted for various activity stages such as resting, normal walking, and fast walking. Results: The coefficient of determination (R²) for the CalTOX model efficiency was 0.9676 and the root-mean-square error (RMSE) was 0.0035, indicating good agreement between predictions and measurements. However, the efficiency index (EI) appeared to be a negative value at -1094.4997. This can be explained as the atmospheric concentration being calculated only from the emissions from industrial facilities in the study area. In the human exposure assessment, the higher the inhalation rate percentile value, the higher the inhalation rate and lifetime average daily dose (LADD) at each activity step. Conclusions: Prediction using the Caltox model might be appropriate for comparing with actual measurements. The LADD of females was higher ratio with an increase in inhalation rate than those of males. This finding would imply that females may be more susceptible to benzene as their inhalation rate increases.

• 대한간호학회지
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• 제36권2호
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• pp.236-243
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• 2006

Purposes: This experimental study was designed to verify the effect of inhalation of essential oils on body weight, feed intake, food efficiency rate and serum leptin. Methods: The subjects of this study were 90 growing SD rats(46 males and 44 females). They were allocated into one of four groups, the Fennel group, Patchouli group, Bergamot group and control group. The experimental treatment was the inhalation of aromatherapy essential oils which was applied two times a day for 10 minutes each during 8 weeks. To evaluate the effects, body weight, feed intake, food efficiency rate and serum leptin were measured before and after the treatment. The collected data was analyzed by repeated measures of Kolmogorov-smirnov test and Normal Q-Q plot for nomality, Kruskal Wallis test and $X^2-test$ for experimental effects with the SPSS program. Results: The food efficiency rate was significantly lower in the Patchouli group and Fennel group than in the Bergamot group and control group(P=.000). No significant group effects were found for SD rat's body weight, feeding amount and serum leptin. Conclusion: In conclusion, these findings indicate that the inhalation of essential oils could be effective in lowering the food efficiency rate rather than the feed intake.

• Journal of Advanced Marine Engineering and Technology
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• 제38권1호
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• pp.23-30
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• 2014

최근 높은 출력을 요구하는 각종 산업분야에서 사용되고 있는 디젤엔진의 효율을 높이기 위해 대응출력 200HP 과급기를 장착한 디젤엔진과 자연흡기식 디젤엔진을 동일한 조건에서 동력계와 배출가스 분석기를 통해 동력특성 및 배출가스 특성을 실험한 논문이다. 자연흡기식 디젤엔진과 과급기를 장착한 디젤엔진을 실험한 결과, 저속에서의 출력특성의 차이는 적었으나 고속에서의 동력특성은 과급기를 장착한 엔진의 출력과 효율이 증가한다는 결과를 얻을 수 있다. 이와는 반대로 배출가스 특성에서는 과급기를 장착한 모델에서 $NO_X$와 $O_2$등의 배출가스가 증가되었으나 $CO_2$의 저감과 동력 특성 증가의 효율을 볼 때 배출가스의 증가치는 적다고 할 수 있다. 이와 같은 결과를 토대로 과급기가 장착된 디젤엔진이 자연흡기식 엔진 대비 효율성 면에서 경제성이 높을 것이라 예측된다.

• 한국산업보건학회지
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• 제32권1호
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• pp.53-63
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• 2022

Objectives: This study was designed to evaluate the filtration efficiency, inhalation resistance, and liquid resistance of commercial reusable masks in comparison to the performance of KF-AD masks (reference masks). Methods: Thirty-six masks were purchased from an online market. Filtration efficiency and inhalation resistance were determined in the same manner as in MFDS certification testing, respectively using TIL/IL & Filter Test 1300S (SFP Services, UK) and Breathing Resistance Analyzer DA2001 (Lambda Ray, South Korea). Results: Most of the filtration efficiencies found for the 19 masks were far lower than the test standard for KF-certified masks. Four masks met KF94 and three masks even met KF80. Most inhalation resistances were also much lower than the standard, with many almost one-half of the standard. In addition, all the masks except KF-AD masks did not pass the liquid resistance test. Conclusions: Although most of the filtration efficiency performance results found in this study for the reusable masks, which emerged as an alternative, were lower than the standard for health masks, multi-use masks can be used with a replacement filter inserted.

• 대한의생명과학회지
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• 제29권4호
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• pp.231-241
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• 2023

Messenger RNA (mRNA)-based vaccines and treatments have recently emerged as a promising strategy. Naked mRNA presents various limitations for direct delivery. Therefore, in this paper, Lipid Nanoparticles (LNPs) were utilized for the delivery of mRNA. Lipid nanoparticle (LNP) mRNA systems are highly effective as vaccines, but their efficacy for pulmonary delivery has not yet been fully established. Additionally, research on effective delivery systems and administration methods for vaccines is required to resolve the stability and degradation issues associated with naked mRNA delivery. This study aimed to determine mRNA delivery efficiency via the inhalation of a lipid nanoparticle (LNP) formulation designed specifically for pulmonary delivery. To this purpose, we built a library of seven LNP configurations with different lipid molar and N/P ratios and evaluated their encapsulation efficiency using gel retardation assay. Among the tested LNPs, LNP1, LNP2-2, and LNP3-2 demonstrated high transfection efficiency in vitro based on FACS analyses luciferase assays, and intracellular accumulation tests. The mRNA delivery efficiencies of the selected LNPs after inhalation and intravenous injection were compared and evaluated. LNP2-2 showed the highest mRNA expression in healthy mouse lungs when aerosolized and was found to be non-toxic. These results indicate that LNP2-2 is a promising carrier for lung mRNA delivery via inhalation.

• 동의생리병리학회지
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• 제16권3호
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• pp.464-471
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• 2002

Author applied several engineering methodologies to classical ultrasonic nebulizer to cope with it's demerits. After several trials and errors, we got the several meaningful results. To evaluate the modified ultrasonic nebulizer for inhalation toxicology of cadmium, author used light-scattering photometer. This paper is the one part of inhalation exposure systems for inhalation toxicology study of cadmium. According to the testing conditions, source temperature 50℃ and inlet-duct band temperature 150℃, aerosol generation results for sodium chloride and cadmium chloride were as followings: Coefficients of variation(CV) of sodium chloride and cadmium chloride for repeated trials were 3.38 and 4.77 for 10g, 2.47 and 5.02 for 5g, and 4.70 and 2.98 for 2.5g. All the CVs were within 10% of acceptance variability. Count Per Minute(CPM) changes of NaCl and CdCl₂ for 5 repeated trials were similar. CPM ratios of CdCl₂/NaCl were 1.13 for 10g, 0.76 for 5g, and 1.06 for 2.5g. Relative aerosol generation of cadmium chloride to sodium chloride was the highest in 10g. Efficiency increases of 24.50% for 5g NaCl, 14.91 % for 2.5g NaCl, and 16.48% for 2.5g CdCl₂ with respect to theoretical efficiency were observed but 0.04% efficiency decrease was observed in 5g CdC₂. According to the modifications of source temperature(20, 50, 70℃) and inlet-duct band temperature(20, 50, 100, 150, 200℃), aerosol generation results for NaCl and CdCl₂ were as followings: CPM trends for each quantity excepting 10g NaCl in inlet-duct band temperature 200℃ were similar, and the highest CPM was observed in source temperature 70℃ to each inlet-duct band temperature. The highest CPMs to 10, 5, and 2.5g NaCl were observed in source temperature 70℃ and inlet-duct band temperature 20℃. Aerosol generation of cadmium chloride was increased with the higher source temperature, excepting inlet-duct band temperature 200℃. The highest CPMs for 10, 5, and 2.5g CdCl₂ were observed in source temperature 70℃ and inlet-duct band temperature 20℃, and this trend was similar to NaCl aerosol generation The highest CPMs for 10, 5, and 2.5g CdCl₂ were observed in source temperature 70℃ and inlet-duct band temperature 20℃, and this result was similar to NaCl aerosol generation. Observed efficiencies of 5 and 2.5g NaCl were similar to ifs theoretical efficiency but -3.08% efficiency decrease of 5g CdCl₂, 17.47% efficiency increase of 2.5g CdCl₂ were observed. CPM ratio of CdCl₂/NaCl of 10g was different to 5 and 2.5g, and 2.5g ratio was higher than 5g ratio. In conclusion, to get maximum aerosol generation for NaCl and CdCl₂ will be the conditions that set the appropriate inlet-duct band temperature for each materials and increase the source temperature. Sodium chloride can be used to evaluate the performance and predict the concentration for cadmium aerosol in aerosol generator and inhalation exposure system.