• Korean Institute of Interior Design Journal
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• v.21 no.2
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• pp.14-22
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• 2012

In regards to museum planning of Korea, it is mainly depending on overseas cases and relevant domestic books without systematic guideline on the space programme in a museum. Therefore, it is urgently required to establish systematic index as it is incapable of proposing detailed analysis and index in accordance with each element. As various problems occurred due to above reason, total floor area of museum was divided by the area of exhibition section, storage section, research section, and public & other area and its ratio was calculated for statistics targeting 614 museums built after 1990's when many public museums were built with the settlement of local self-governing system and the type of museums was diversified. It was again classified into 4 elements of period, region, scale, and type and then the influence of each element on each section of museum was understood through integrated analysis. First, looking into the space programme in regards to total floor area, the floor area ratio of exhibition section, storage section, and research section decreased and the floor area ratio of public & other area increased with the increase in total floor area. It was because not only rest area but also a space to enjoy various cultures, gaining new experience, and accumulate knowledge is located in public & other area. Second, it was revealed that the ratio of exhibition section and storage section has been decreasing since 1990's and ratio of research section and public & other area has been increasing as they can play various roles such as the education and convenience to satisfy cultural desires of visitor in accordance with current trend. Third, it was proved that floor area ratio of exhibition section is lower than storage section in museums located in highly urbanized region. In addition to this, it was revealed that the floor area ratio of research section is in proportion to the population density. As a result of study, significant relation was displayed in scale, era, and region among 4 elements thus it could be utilized as reference for the space programme of domestic museum planning in the future.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.6
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• pp.513-523
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• 2017

aim of this study was to analyze the effectiveness of improved self - management leadership competence through 'self - management leadership'. This study aims to contribute to the development of self - management competency curriculum of universities. The subjects of this study were students who took core competency classes at D university in Seoul. The study group consisted of 221 subjects in the experimental group,who took the contents and 204 participants in the control group,who did not take the contents. The experimental group showed higher improvement than the control group. The experimental group showed greater improvement. In addition, the goal management competence was the highest in terms of the improved competence recognized by students who took courses in self-management and leadership. An analysis of the perceptions about self-management leadership competence enhancement showed that among self-management, goal management, relationship formation, leadership, collaboration, an goal management competence was improved the most. In the self - management domain, the highest improvement was observed in the areas of personality, self - reflection, self - confidence. In the goal management area, the areas of time management, goal setting, and vision were the most improved. Communication, listening, interpersonal relationship, and coaching questions showed the most perceived improvement among the relationship formation. In terms of leadership competency, problem solving and influence were the most improved areas, For collaboration competency, it was found that competency was the most improved at team play.

• The Journal of the Korea Contents Association
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• v.14 no.8
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• pp.505-516
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• 2014

This study was aimed at identifying the influence of Creative Thinking Filtering Mode program in international gifted program: how much it influences to improve the cognitive domains of creativity (fluency, flexibility, originality) and affective domains of creativity (independence, curiosity, diversity, sensitivity, sense of humor, individuality. To analyze data, ANCOVA(Analysis of Covariance)test was conducted, and the results are as belows. Firstly, the group applied in CTFM program was higher than controlled group on the domains of cognitive and affective. Specifically, in the factors of fluency, flexibility and originality among three cognitive domains and factors of individuality.In affective domains of creativity, independence, curiosity, diversity, a sense of humor among the five factors except of sensitivity were higher. Secondly, the result of analyzing the difference between before and after applying CTFM program was that three elements in cognitive domains : fluency, flexibility and originality improved, especially, the fluency was the most improved. Thirdly, the result of analyzing the difference of affective factor between before and after applying CTFM program was that the originality, diversity, a sense of humor and individuality among the 6 elements of affective domain improved, especially the individuality was the most improved.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.6
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• pp.2660-2667
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• 2011

TREK-1 channel is a member of the two-pore domain potassium (K2P) channel family that is regulated by intracellular pH, membrane stretch, polyunsaturated fatty acids, temperature, and some neuroprotectant agents. TREK-1 channel can influence neuronal excitability by regulating leakage of potassium ions and resting membrane potential. TREK-1 channel has been shown to be overexpressed in prostate cancer cells. Although the importance of these properties, relatively little is known about flavonoid effects in the regulations of TREK-1 channel. The purpose of the study was to screening of flavonoids as the TREK-1 channel modulator using one of electrophysiological techniques such as excised inside-out patch configuration. We demonstrated blocking effect on TREK-1 channel by flavonoids such as epigallocatechin-3-gallate (EGCG), curcumin and quercetin in CHO cells transiently expressing TREK-1 channel. The inhibition of TREK-1 channel by quercetin and curcumin was reversible, whereas EGCG was little reversible. Quercetin, EGCG and curcumin decreased the relative channel activity to 73%, 91% and 94%, respectively. The half-inhibitory concentration (IC50) of curcumin, quercetin and EGCG was $1.04{\pm}0.19\;{\mu}M$, $1.13{\pm}0.26\;{\mu}M$ and $13.5{\pm}2.20\;{\mu}M$ in CHO cells expressing TREK-1 channel, respectively. These results indicate that flavonoids might regulate TREK-1 and this regulation might be one of the pharmacological actions of flavonoid in nervous systems and cancer cells.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.11
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• pp.4999-5003
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• 2016

The testicular cancer (TCa) incidence is increasing in many countries, with age-standardized incidence rates up to 7.8/100,000 men in the Western world, although reductions in mortality and increasingly high cure rates are being witnessed at the same time. In Africa, where rates are lower, presentation is often late and morbidity and mortality high. Given this scenario, awareness of testicular cancer and practice of testicular self-examination among future first response doctors is very important. This study was conducted to determine knowledge and attitude to testicular cancer, and practice of testicular self-examination (TSE) among final (6th) year medical students. In addition, the effect of an intervention in the form of a single PowerPoint(R) lecture, lasting 40 minutes with image content on testicular cancer and testicular self examination was assessed. Pre and post intervention administration of a self-administered structured pre tested questionnaire was performed on 151 medical students, 101 of whom returned answers (response rate of 66.8%). In the TC domain, there was a high level of awareness of testicular cancer, but poor knowledge of the age group most affected, with significant improvement post intervention (p<0.001). Notable also was the poor awareness of the potential curability of TC, this also being improved following the intervention (p<0.001). A poor level of awareness and practice of testicular self-examination pre-intervention was found considering the nature of the study group..Respondents had surprisingly weak/poor responses to the question "How important to men's health is regular testicular self-examination?" Answers to the questions "Do you think it is worthwhile to examine your testis regularly?" and "Would you be interested in more information on testicular cancer and testicular self-examination?" were also suboptimal, but improved post intervention p<0.001, p<0.001 and p=0.037. Age, gender and marital status were without specific influence. In conclusion, this study showed poor levels of knowledge regarding epidemiology of TCa and its potential curability when detected early. There was also a poor awareness of, practice of, and poor attitudes to TSE. The significant improvement in these parameters post intervention indicates value in educational intervention. We recommend inclusion of TCa coverage and TSE teaching in the secondary school curriculum (targeting adolescents). Greater emphasis should also be given to testicular cancer in the curricula of medical schools and other training institutions for health care personnel.

• Journal of the Korean Society of Hazard Mitigation
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• v.7 no.5
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• pp.73-78
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• 2007

It has been increasing that significant loss of life and property due to global wanning and extreme weather, and the climate and temperature changes in Korea Peninsula are now greater than the global averages. Climate information from regional climate models(RCM) at a finer resolution than that of global climate models(GCM) is required to predictclimate and weather variability, changes, and impacts. The new surface boundary conditions(SBCs) development is motivated by the limitations and inconsistencies of existing SBCs that have influence on model predictability. A critical prerequisite in constructing SBCs is that the raw data should be accurate with physical consistency across all relevant parameters and must be appropriately filled for missing data if any. The aim of this study is to construct appropriate SBCs for the RCM in Asia domain which will be used for the prevention of disasters due to climate changes. As all SBCs have constructed onto the 30km grid-mesh of the RCM suitable for Asia applications, they can be also used for other distributed models for climate and hydrologic studies.

• Korean journal of communication and information
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• v.81
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• pp.122-152
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• 2017

The media movement is a movement to separate from the political power and to dismantle the media power and to seek the control of citizens' media. Political power is the biggest factor that violates the fairness and independence of the media in the public domain. On the other hand, the factor that interferes with the healthy and responsible media of the press in the private sector is the media power originating from the owner. Citizens 'media campaign emphasizes citizens' mobility as a subject that monitors the political power and media power that have the sovereignty of the media belonging to the citizen and may infringe on this sovereignty.In the Lee Myung Bak - Park Geun Hye regime, the civil press movement was a period of resistance and struggle. Citizen media campaigns have completely collapsed with governance. As a result, the intellectuals who have expertise in the media have lost their place in the discussion and presentation of the policy alternatives in which the policy production is centered. The influence of citizen media organizations, which are centered on activists rather than citizen's direct action, is limited. In order to strengthen the power of the media reform, it is necessary to reconstruct social forces such as civil society, media unions, media organizations and political forces. We should also look for various ways in which citizens can participate actively in the agenda and activities of the movement. In addition, it is necessary to expand the movement of the media.

• Journal of the Korean Association of Geographic Information Studies
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• v.9 no.2
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• pp.144-159
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• 2006

Hydrological models are tools intended to realistically represent the basin's complex system in which hydrological characteristics result from a number of physical, vegetative, climatic, and anthropomorphic factors. Spatially distributed hydrological models were first developed in the 1960s, Remote sensing(RS) data and Geographical Information System(GIS) play a rapidly increasing role in the field of hydrology and water resources development. Although very few remotely sensed data can applied in hydrology, such information is of great. One of the greatest advantage of using RS data for hydrological modeling and monitoring is its ability to generate information in spatial and temporal domain, which is very crucial for successful model analysis, prediction and validation. In this paper, SLURP model is selected as semi-distributed hydrological model and MODIS Leaf Area Index(LAI), Normalized Difference Vegetation Index(NDVI) as Remote sensing input data to hydrological modeling of Kyung An-chen basin. The outlet of the Kyung An stage site was simulated, We evaluated two RS data, based on ability of SLURP model to simulate daily streamflows, and How the two RS data influence the sensitivity of simulated Evapotranspiration.

• IMMUNE NETWORK
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• v.6 no.4
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• pp.192-198
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• 2006

Background: Investigating strategy to enhance efficiency of gene transfer via adenovirus is critical to sustain gene expression in targeted cells or tissues to regulate immune responses. However, the use of adenovirus as a gene delivery method has been limited by the native tropism of the virus. In this study, the critical parameter is to improve the efficient binding of viral particles to the plasma membrane prior to cellular uptake. Methods: Human immunodeficiency virus (HIV-1) trans-acting activator of transcription (TAT), a protein transduction domain, was fused to the ectodomain of the coxsackie-adenovirus receptor (CAR). The CAR-TAT protein was produced from a Drosophila Schneider 2 cells (S2) transfected with CAR-TAT genes. The function of CARTAT was analyzed the efficiency of adenoviral gene transfer by flow cytometry, and then immunizing AdVGFP with CAR-TAT was transduced on dendritic cells (DCs). Results: S2 transfectants secreting CAR-TAT fusion protein has been stable over a period of 6 months and its expression was verified by western blot. Addition of CAR-TAT induced higher transduction efficiency for AdVGFP at every MOI tested. When mice were vaccinated with DC of which adenoviral transduction was mediated by CAR-TAT, the number of IFN-${\gamma}$ secreting T-cells was increased as compared with those DCs transduced without CAR-TAT. Conclusion: Our data provide evidence that CAR-TAT fusion protein enhances adenoviral transduction and immunogenecity of transgenes on DCs and may influence on the development of adenoviral-mediated anti-tumor immunotherapy.

• Korean Journal of Social Welfare
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• v.61 no.4
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• pp.5-33
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• 2009

This study attempted to evaluate the effectiveness of the Supportive Project for the Priority Region of Educational Welfare Investment(SPPREWI) which has been put into action in Korea as a part of national policies for poor school children. In so doing this study aimed to test SPPREWI's legitimacy as well as whether we have to continue this program or not. In order to fulfill this research purpose researchers identified several outcome indicators of SPPREWI, which represent psychosocial and cognitive adjustment. The variables pertaining to psychosocial adjustment domain are: self-concept; depression, anxiety, and suicidal impulse; inclination of assault and indignation; delinquency; school life adjustment; and change in social relations. The variables of cognitive adjustment include recognition of self-control in learning; control strategy of learning behavior; and preparedness for job hunting. In this study the quasi-experimental group contained students from schools which are under the SPPREWI. The control group was composed of students from schools which were free from SPPREWI but under the influence of deteriorating school environment. The quasi-experimental group and the control group were compared in terms of outcome indicators presented earlier. Within the quasi-experimental group both the students below poverty-line and the students above poverty-line were divided into two groups each by the level of service use, and were compared in terms of the outcome variables presented earlier. Study results supported the argument that SPPREWI was effective generally in improving students' school adjustment. Study results also showed that the variable of 'school nurturance' played a significant role in moderating the effect of SPPREWI on a couple of outcome variables specially when schools' overall educational environment was in poor condition. Implication as well as suggestion were presented on the basis of study findings.