• Parasites, Hosts and Diseases
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• 제55권5호
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• pp.569-573
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• 2017

The present study was performed to reveal the current status and risk factors of Strongyloides stercoralis infections in the villages of Kenethao district, Xayaburi Province, Lao PDR. Fecal specimens were collected and examined for S. stercoralis using Koga-agar plate culture technique. Among 516 individuals, the prevalence of S. stercoralis and hookworm infection was 44.2% and 17.1%, respectively. Co-infection was detected in 13.2% of the cases. The prevalence did not significantly differ between males and females (P=0.193). However, the prevalence of S. stercoralis infection increased significantly with age (P=0.041). Of the risk factors examined, both performing farming activities (P=0.001) and walking barefoot when going outside of the house (P=0.003) showed significant correlations with S. stercoralis infections. Our results suggest that S. stercoralis is highly endemic in this area. The National Helminth Control Program of Lao PDR should take actions to control S. stercoralis infection. In addition, provision of health education about the benefits of wearing shoes would be important for reducing infection in the study area. Moreover, the application of high-sensitivity diagnostic approaches is needed to obtain the true impact of S. stercoralis infections in all rural communities in order to provide surveillance activities in Lao PDR.

• 한국의료질향상학회지
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• 제8권1호
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• pp.10-21
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• 2001

Background : The Clostridium difficile is the most important identifiable cause of nosocomial infectious diarrhea and colitis, which lengthens hospital stay. Recently incidence of C. difficile has been increasing in an university hospital, and an intervention for prevention and control of C. difficile associated diarrhea (CDAD) was in prompt need. Methods : Subjects were the patients in the neurosurgical intensive care unit(NCU) where C. difficile was most frequently isolated. To increase participation of various departments, we used the CQI method, because management of CDAD requires a wholistic approach including control of antibiotics, barrier precaution and environmental cleaning and disinfection. Duration of the CQI activities was 9 months from April to December 1999. Results : The identified problems were misuse and overuse of antibiotics, lack of consciousness of medical personnels and the possibility of transmission from the contaminated environment and tube feeding. Education for proper use of antibiotics and management of C. difficile infection, use of precaution stickers, supplement of handwashing equipments, emphasis on environmental disinfection, and the change of the process of tube feeding were done. The CDAD rate in NCU was significantly decreased after the CQI program (8.6 case per 1,000 patient days from January to April 1999 vs 4.8 from May to December 1999). The distribution of neurosurgical wards including NCU among the total number of isolated C. difficile from the clinical specimens dropped from 49.4% in January to April to 33,7% in May to December. The average hospital stay of the neurosurgical department changed from 19.6 days to 15.2 days. Also, the effect of the CQI activities for C. difficile may have affected the incidence of vancomycin resistant enterococci (VRE). Duration and dosage of certain antibiotics used in the NS department were decreased. The distribution of neurosurgical department in the number of VRE isolated patients declined from 18.4% to 11.1%. Conclusion : Infection control of resistant organisms such as C. difficile is likely to be successful when management of environmental contamination an collaborative efforts of decreasing the patients' risk factors such as antibiotics management and decreasing the length of hospital stay come simultaneously. For this work, related departments need to actively participate in the entire process under a common target through discussions for identifying problems and bringing up solutions. In this respect, making use of a CQI team is an efficient method of infection control for gathering participation and cooperation of related departments.

• The Plant Pathology Journal
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• 제23권3호
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• pp.166-173
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• 2007

In a trial to select suitable fungicides for developing a spray program that can control apple white rot effectively, after-infection activities in some protective fungicides were detected. Six fungicides, mancozeb, propineb, benomyl, folpet, azoxystrobin and iminoctadine-triacetate, which had been extensively used in apple orchards, were sprayed on 12-year-old apple trees (cv. Fuji) at 15-day intervals from late May to late July. Disease incidences and infection frequencies of the fruit bagged just before and soon after each spray were examined. When the infection frequency or disease incidence of the fruit bagged after each spraying of fungicide was significantly lower than those of the fruit bagged before spraying, the fungicides appeared to confer after-infection activity. The six fungicides showed diverse activities on white rot: folpet showed after-infection activity on disease development, iminoctadine-triacetate showed after-infection activity on infection, azoxystrobin showed after-infection activity on disease development and infection, and mancozeb, propineb and benomyl showed no distinct activity. The activity of a fungicide became much higher when it was sprayed alternately with other fungicide rather than successive spraying of the same fungicide. Analysis of the properties of these protective fungicides could lead to the development of a highly effective spray program against white rot.

• Journal of Microbiology and Biotechnology
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• 제22권9호
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• pp.1224-1229
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• 2012

Puerarin (P), an isoflavone derived from kudzu roots, has strong biological activities, but its bioavailability is often limited by its low water solubility. To increase its solubility, P was glucosylated by three dextransucrases from Leuconostoc or Streptococcus species. Leuconostoc lactis EG001 dextransucrase exhibited the highest productivity of puerarin glucosides (P-Gs) among the three tested enzymes, and it primarily produced two P-Gs with a 53% yield. Their structures were identified as ${\alpha}$-$_D$-glucosyl-($1{\rightarrow}6$)-P (P-G) by using LC-MS or $^1H$- or $^{13}C$-NMR spectroscopies and ${\alpha}$-$_D$-isomaltosyl-($1{\rightarrow}6$)-P (P-IG2) by using specific enzymatic hydrolysis, and their solubilities were 15- and 202-fold higher than that of P, respectively. P-G and P-IG2 are easily applicable in the food and pharmaceutical industries as alternative functional materials.

• 한국융합학회논문지
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• 제9권3호
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• pp.121-129
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• 2018

본 연구의 목적은 간호사의 감염관리 중요도와 건강신념이 자신들의 감염관리 수행도에 영향을 미치는 요인을 파악하고자 함이다. 본 연구대상자는 D시의 종합병원에서 근무하는 간호사 142명 대상으로 2016년 12월 10일부터 15일까지 수집되었다. 간호사의 감염관리 중요도와 건강신념 중 인지된 장애성이 대상자의 감염관리 수행도에 영향을 미치는 요인(F=43.61, p<.001)으로 확인되었으며, 감염관리 수행도에 대한 이 두 요인의 설명력은 38.0% 이었다. 따라서, 간호사의 감염관리 수행도를 높이기 위해서는 무엇보다 감염관리활동이 중요하다는 것을 지속적으로 인식시키는 교육이 필요하다. 다만 감염관리 실천이 간호사에게 업무 부담이나 고통으로 인식되지 않도록 하는 제도적 보완도 함께 고려되어야 할 것이다.

• Perspectives in Nursing Science
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• 제14권1호
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• pp.1-9
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• 2017

Purpose: To study the internal psychological conflicts among nursing students during an infection control protocol carried out in the hospital by measuring their observation skills and performance during clinical training. Methods: Investigation of both pre- and post- infection control was conducted using questionnaires for clinical infection practices. We identified and evaluated the students' observation skills, clinical performance, clinical perception, and internal conflict regarding clinical infection control. We also interviewed the students as part of our study. Results: Among parameters such as clinical performance, observation skills, clinical perception, and internal conflict, the average observation skills (t=5.49, p<.001) were significantly lower, while internal conflict among students (t=-7.23, p<.001) was significantly higher than expected prior to clinical training. Generally, there was a negative correlation between observation skills and internal conflict in every aspect of infection control practice (r=-.281, p=.031). Internal conflict was significantly higher than expected in the context of hand hygiene (t=-2.135, p=.037), personal hygiene (t=-3.48, p=.002), and ventilator management (t=-3.69, p<.001). Clinical performance of students in the context of hand hygiene (t=4.69, p<.001), personal hygiene (t=2.06, p=.044), and ventilator management (t=2.68, p<.001) was significantly lower than expected prior to clinical training. Conclusion: Our findings showed that internal psychological conflict is higher when infection control practices are observed or performed to a lesser degree. Therefore, reinforcing education regarding infection control among students, such as developing a systematic program, or consecutive training and monitoring, is suggested.

• 한국산학기술학회논문지
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• 제18권7호
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• pp.466-475
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• 2017

본 논문은 요양병원의 감염관리 현황을 파악하기 위하여 2016년 5월 1일부터 7월 31일까지 영남지역의 인증평가를 받은 156개 요양병원을 대상으로 자료 수집을 하였다. 현황 파악에서 있으면 '예', 없으면 '아니오', 중요도 인식은 5점 척도의 총 85문항으로 구성된 설문지를 이용하였다. 자료 분석에 사용된 설문지는 107부이며 자료 분석은 SPSS/WIN 22.0 Program을 이용하였다. 감염관리위원회는 80.4%에서 있다고 하였으며 중요도는 3.79로 나타났고, 감염관리 담당자는 86.0%에서 있으며 대부분 겸임이다. 감염관리규정은 손위생을 포함한 7개 문항에서 100% 구비하고 있으며 규정에 대한 중요도는 손위생이 4.47로 가장 높게 인식하고 있다. 감염관리 활동은 직원교육이 시행 빈도와 중요도 인식에서 가장 높게 나타났으며, 감염관리 수행률은 멸균물품 유효기간 준수율이 96.3%이고 중요도가 4.64로 가장 높게 나타났다. 요양병원의 감염관리 규정은 어느 정도 갖추어져 있으나 감염관리 전담인력 부족과 요양병원에서 적용 가능한 감염관리 규정 미비로 감염관리 활동이 제대로 이루어지지 못하고 있는 것으로 나타났다. 그러므로 요양병원에 적용 가능한 감염감시기준 및 감염관리 가이드라인 개발과 이를 적용할 감염관리 전담인력이 필요하다.

• Journal of Preventive Medicine and Public Health
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• 제42권6호
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• pp.408-415
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• 2009

Objectives : This study was performed to investigate the mumps transmission control status and inapparent infection rate among middle and high school students in Daegu City during a mumps outbreak. Methods : Nine schools (two middle schools and seven high schools), which reported a number of mumps cases between 2007 and 2008 were selected for investigation. During March-May 2008, a standard questionnaire was distributed to gather information about case identification, instructed isolation measure, isolation status of mumps cases and related factors, and outdoor activities of nonisolated mumps case. Inapparent infection rate was estimated by serum mumps IgM and IgG antibodies status and self-reported mumps symptoms in three of the nine schools. Results : Among 2,560 respondents, more than half of students answered that they did not receive instructions in mumps transmission control measures during the outbreak. Among the 327 mumps cases identified by the questionnaire, 131 cases (40.1%) were considered as isolated and the isolation rates were significantly different among schools, grades, and gender. Of the non-isolated cases, 88.3% continued attending school. Inapparent mumps infection rates were between 56.3% and 70.2%. Conclusions : Mumps transmission control was inadequate to control the mumps outbreak. Although high inapparent infection rate would mitigate the transmission control effect of case isolation, this measure is fundamental for infection control. The reasons of this inadequate status need to be explored to develop an effective intervention strategy.

• 동서간호학연구지
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• 제11권2호
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• pp.137-145
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• 2005

Purpose: This study has been attempted as one of the Quality Improvement activities in order to provide with intravenous injection control and to confirm the evaluation from the patients and their guardians, and also from nurses themselves. Method: The subject of this intravenous injection control was a control group of 239 patients and 176 nurses, a comparison group of 128 patients and 146 nurses. The tool consisted of hospitality (towards patients), explanation, and infection prevention activities. The collected data were analysed using SPSS Windows 11.0 program for percentage, $X^2$-test and t-test. Result: 1) The nurses who were instructed in standardised intravenous injection control received more satisfactory evaluation from the patients(t=-2.89, p=.004) than the nurses who were not. However, in the subdivisions, the explanation field was the only one to receive a more satisfactory evaluation(t=-1.14, p=.255). 2) The nurses who were instructed in standardised intravenous injection control showed higher performances in intravenous injection control (t=-4.21, p=.000) than the nurses who were not. In the subdivisions, hospitality, explanation, and infection prevention activities all showed effectiveness ($t=-2.35{\sim}3.90$, $p=.020{\sim}.000$). Conclusion: From the results stated above, it can be concluded that standardised intravenous injection control instruction for nurses brought out better evaluation, i.e. satisfaction, from the patients and their guardians, and the nurses who received the instruction showed better performances in intravenous injection control.

• 한국방사선학회논문지
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• 제13권5호
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• pp.739-747
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• 2019

본 연구는 경남지역 의원에 근무하는 방사선사를 대상으로 감염관리에 대한 연구로 감염관리에 대한 인지도와 수행도를 분석하여, 지역의원에 근무하는 방사선사의 감염관리 교육을 위한 기초자료를 제공하고자 시행하였다. 연구에 사용한 도구는 설문지로 2018년 04월01일부터 08월31일까지 경남에 소재하는 의원에 근무하는 방사선사를 대상으로 설문지 총150부를 배부하여 연구에 적합한 131부를 SPSS 18.0 통계 프로그램을 이용하여 분석하였다. 감염관리에 대한 요인으로는 감염관리에 대한 특성 12문항과 감염관리에 대한 인지도 및 수행도로 총60문항으로 분석하였다. 연구대상자의 일반적 특성을 기준으로 기술통계, t-test, ANOVA, 상관관계 및 회귀분석을 하였다. 감염관리에 대한 인지요인에 대한 총인지도는 $4.13{\pm}.05$점으로 높게 나타났으며, 수행요인에 대한 총수행도는 $4.05{\pm}.05$점으로 높게 나타나 감염관리에 대한 인지도 및 수행도에서 경남지역 의원에 근무하는 방사선사들의 감염관리 수준은 수행도가 인지도에 비해 조금 낮게 나타났지만, 비교적 높은 것으로 분석되었다. 지역의원 방사선사의 감염관리는 병원을 운영하는 의료진의 지속적인 감염교육 활동과 예방활동을 통해 의원에 근무하는 방사선사 역시 감염관리의 전문가로 자리 매김하여야 할 것이다.