• Clinical Nutrition Research
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• 제12권1호
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• pp.40-53
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• 2023

Differential bitterness perception associated with genetic polymorphism in the bitter taste receptor gene taste 2 receptor member 38 (TAS2R38) may influence an individual's food preferences, nutrition consumption, and eventually chronic nutrition-related disorders including cardiovascular disease. Therefore, the effect of genetic variations on nutritional intake and clinical markers needs to be elaborated for health and disease prevention. In this study, we conducted sex-stratified analysis to examine the association between genetic variant TAS2R38 rs10246939 A > G with daily nutritional intake, blood pressure, and lipid parameters in Korean adults (males = 1,311 and females = 2,191). We used the data from the Multi Rural Communities Cohort, Korean Genome and Epidemiology Study. Findings suggested that the genetic variant TAS2R38 rs10246939 was associated with dietary intake of micronutrients including calcium (adjusted p = 0.007), phosphorous (adjusted p = 0.016), potassium (adjusted p = 0.022), vitamin C (adjusted p = 0.009), and vitamin E (adjusted p = 0.005) in females. However, this genetic variant did not influence blood glucose, lipid profile parameters, and other blood pressure markers. These may suggest that this genetic variation is associated with nutritional intake, but its clinical effect was not found. More studies are needed to explore whether TAS2R38 genotype may be a potential predictive marker for the risk of metabolic diseases via modulation of dietary intake.

• 천문학회지
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• 제38권2호
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• pp.261-266
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• 2005

This paper reviews the progress in the VLBI (Very Long Baseline Interferometry) studies of Sgr A$\ast$, the best known supermassive black hole candidates with a dark mass concentration of $4 {\times} 10^6 M_{\bigodot}$ at the center of the Milky Way. The emphasis is on the importance of the millimeter and sub-millimeter VLBI observations in the detection of Sgr A$\ast$'s intrinsic structure and search for the structural variation.

• 경영과학
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• 제11권2호
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• pp.29-41
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• 1994

This paper analyses the stochastic nature of the Permanent Income Hypothesis (PIH) by specifying the variance-covariance structure of PIH based on Hall and Mishkin[3]. Maximum likelihood is employed to estimate the model by explicitely incorporating the heteroscedastic nature of the data into the likelihood. The data used are individual Korean household consumption and income data. The results indicate that the data are generally consistent with the Permanent Income Hypothesis, and about 11 percent of the total variation in consumption may be attributable to the excess sensitivity of consumption to income.

• 한국고분자학회:학술대회논문집
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• 한국고분자학회 2006년도 IUPAC International Symposium on Advanced Polymers for Emerging Technologies
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• pp.173-173
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• 2006

We have explored a strategy to control the supramolecular nano-structures self-assembled from rigid segments through attachment of flexible chains through microphase separation and anisotropic arrangement. Supramolecular structures formed by self-assembly of rigid building blocks can be precisely controlled from 1-D layered, 3-D bicontinuous cubic to 2-D cylindrical structures by systematic variation of the type and relative length of the respective blocks. Furthermore, depending on the individual molecular architectures, rigid building blocks self-assemble into a wide range of supramolecular structures such as honeycomb, disk, cylinder, helix, tube, barrel stave, and nano-cage.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1992년도 추계학술대회
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• pp.58-62
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• 1992

Hybrid optical-electronic procedures are introduced for the automated estimation of cell parameters (e.g., size, size variation, and shape). Two different optical Fourier analysis procedures are applied to high contrast cell boundary patterns obtained from specular micrographs of the endothelial layer. In one case, a large number of cell patterns are illuminated to extract average cell size information. Once the average cell size information has been obtained, individual cells are illuminated to extract shape information.

• 대한교통학회지
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• 제23권5호
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• pp.7-14
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• 2005

교통혼잡은 통행시간의 손실과 에너지 낭비뿐만 아니라 막대한 사회적 비용을 발생시킨다. 서울시는 도심통행료 도입, 대중교통체계개편 등 다양한 교통정책을 실행해 오고 있으나, 수도권외곽의 택지개발등으로 시계 유출입 교통량은 크게 증가하고 있는 추세이다. 본 연구의 목적은 광역급행버스시스템 (Bus Rapid Transit: BRT)과의 정책결합을 통한 혼잡통행료제도 확대시행에 따른 지불의사액 (Willingness-To-Pay: WTP)을 추정하는 것이다. 분석을 위해 가구방문 직접면접조사를 실시하였다. 본 연구는 크게 두 가지 부분으로 구성되어 있다. 첫째는 일인당 지불의사액 분석이고 둘째는 형평성 분석이다. 일인당 지불의사액 분석은 개별 시나리오에 대한 통행자가 현재 통행수단 유지를 위한 보상변화(Compensating Variation, CV)규모를 지불의사액의 개념에 따라 측정하는 것이다. 지불의사액 도출을 위해서는 조건부가치측정법(Contingent Valuation Method : CVM)을 적용하였다. 형평성 분석은 정책 시나리오에 대해 통행자를 소득계층별로 구분하여 현재 통행수단 유지를 위한 보상변화를 측정하고, 이것이 계층별 평균소득에서 차지하는 비중을 계산함으로써 정책 시행효과를 확인하는 것이다.

• Imaging Science in Dentistry
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• 제42권3호
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• pp.175-182
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• 2012

Purpose: The aim of this study was to provide sex-matched three-dimensional (3D) statistical shape models of the mandible, which would provide cephalometric parameters for 3D treatment planning and cephalometric measurements in orthognathic surgery. Materials and Methods: The subjects used to create the 3D shape models of the mandible included 23 males and 23 females. The mandibles were segmented semi-automatically from 3D facial CT images. Each individual mandible shape was reconstructed as a 3D surface model, which was parameterized to establish correspondence between different individual surfaces. The principal component analysis (PCA) applied to all mandible shapes produced a mean model and characteristic models of variation. The cephalometric parameters were measured directly from the mean models to evaluate the 3D shape models. The means of the measured parameters were compared with those from other conventional studies. The male and female 3D statistical mean models were developed from 23 individual mandibles, respectively. Results: The male and female characteristic shapes of variation produced by PCA showed a large variability included in the individual mandibles. The cephalometric measurements from the developed models were very close to those from some conventional studies. Conclusion: We described the construction of 3D mandibular shape models and presented the application of the 3D mandibular template in cephalometric measurements. Optimal reference models determined from variations produced by PCA could be used for craniofacial patients with various types of skeletal shape.

• 한국지반공학회지:지반
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• 제9권3호
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• pp.77-90
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• 1993

얕은기초의 침하해석에 관련된 토질정수, 하중 및 지층구조는 많은 불확실성을 내포하고 있어 확률적 특성을 고려한 해석이 필요하다. 본 연구는 Monte Carlo Method를 이용하여 독립후팅들로 구성된 얕은기초의 침하에 관한 확률론적 해석을 하였다. 변수의 불확실성을 고려하기 위하여 토질정수와 하중은 정규분포의 확률변수로 가정하여 독립후팅의 침하평균 및 변동계수를 구하고 각 독립후팅의 침하도 정규분포하는 것으로 가정하였다. 또한 지반내에 존재할 수 있는 연약토질 포켓 (soft soil pocket)의 확률을 고려한 각 독립후팅의 침하는 Markov process를 따르는 것으로 하였다. 이와같은 각 변수들의 변화에 따라 최대침하와 부등칭하의 허용한계 초과확률에 대한 민감도분석을 하였으며, 얕은기초의 침하해석은 각 변수의 불확실성과 지반조건을 고려하는 것이 타당하다고 판단된다.

• 한국지구과학회지
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• 제31권3호
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• pp.259-266
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• 2010

학습자의 개별 정답 문항에서 얻어지는 단편적인 정보들로부터 평가에 관련되는 지식 전체에 대한 정보를 추론할 수 있는 지식공간론을 활용하여 고등학생의 천문학적 공간개념에 대한 위계와 개별 학생의 지식상태를 분석하였다. 천문학적 공간개념을 구성하는 요인의 위계는 '공간위치$\ll$공간추리$\ll$공간변화'로 분석되었다. 또한 지식공간론을 활용한 평가 자료의 분석은 기존의 평가 방법으로는 알 수 없었던 평가 문항과 문항 간의 관계와 학생 개개인의 지식상태를 알 수 있게 함으로서 학습자의 수준별 개별화 학습과 교육과정 선정에서 많은 시사점을 찾을 수 있다.

• 한국식생활문화학회지
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• 제23권4호
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• pp.489-498
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• 2008

The objectives of this study were to provide fundamental information on how individual phenolic compounds form on the inside of apple slices during cold storage, the changes in the content of four types of phenols, ingredient variation of individual phenolic compounds and the influence of phenolic compounds on enzymatic browning. This study measured the changes in the content of soluble solids, pH and vitamin C in order to investigate the correlations between these variables. HD and FA were the main phenolic compounds found in the apple slices, and HD was the most prevalent phenol. Furthermore, comparison of the CG and EP content revealed that there were more CGs than EPs. The phenol content tended to decrease considerably in the fresh apple slices and water-dipped apple slices but only slightly in the CP from sucrose-dipped apple slices and 0.5% ascorbic acid solution-dipped apple slices. The degree of browning increased in the following order: fresh apple slices, water-dipped apple slices, 0.5% ascorbic acid solution-dipped apple slices and CP from sucrose-dipped apple slices. The vitamin C content tended to decrease in the fresh apple slices, water-dipped apple slices, 0.5% ascorbic acid solution-dipped apple slices and CP from sucrose-dipped apple slices. The pH tended to increase in all sample groups, but the pH of the water-dipped apple slices was lower than that of the comparison group. The CP from sucrose-dipped apple slices had the lowest value of pH. The change in soluble solids tended to increase in all treatment groups, but this increase was less in the CP from sucrose-dipped apple slice. Correlation analysis revealed a high degree of correlation between browning and chlorogenic acid content. The results of the present study show that, when stored in the fridge, the change in phenol ingredient content in apple slices influences the browning of the slices. The results also showed that HD and FA were the main phenolic compounds, while CG was shown to have the greatest influence on browning.