• KSBB Journal
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• 제27권6호
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• pp.367-374
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• 2012

Cigarette smoking (SM) is considered to be well known environmental toxin which contributes to the onset of various diseases. SM cause direct lungs damage, activate lungs inflammatory responses, and in some cases leads to the development of lung cancer. Cytokines in injured starfish (Asterina pectinifera) is the potential changes in its expression during the regeneration process. Especially, expression of TGF-${\beta}1$ has increased in arm cut starfish extract after eight days. Also, starfish including saponin like the ginseng. Saponin is widely used in the world because of some effective pharmacological activities. Therefore, the current study was designed to elucidate the pharmacological activities of starfish extract against cigarette smoking induced damage in cell line and pulmonary tissue. We investigate that the effect of eight days starfish extract after arm cut (8d) and intact starfish extract on cell line and mouse lung injury by SM. In cell proliferation analysis, although cigarette smoking extract (CSE) was co-treated, the higher proliferation ability is shown in 8d treatment than intact starfish extract. 8d and intact starfish extract was directly transported to pulmonary cells through respiratory organ by nebulizer inhalation. In this case of cigarette smoking, the pulmonary structure was damaged and functions become abnormal. However, 8d treated groups showed similar with the control group compared with SM group. Among them, 8d was proved to be more effective than intact starfish extract. These results demonstrate that 8d could more protect pulmonary structure and function than intact starfish extract against cigarette smoking by ginseng like saponin and regulation of inflammatory cytokines.

• 한국통신학회논문지
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• 제42권5호
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• pp.1110-1116
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• 2017

동작 특성에 따라 궤도회로 장치는 신호기 장치, 선로전환기 및 기타 안전과 관련된 장치의 직접 또는 간접 제어를 위해 설치되며, 주로 열차의 검지, 지상에서 차상으로 제어정보 전송, 궤도 깨짐 검지 및 귀선 전류 전송에 사용된다. 특히 귀선 전류는 신호시스템, 전력시스템 및 전차선 및 궤도회로장치와 관련이 있다. 신호시스템에서 가장 중요한 구성 요소 중 하나인 귀선 전류는 선로변 유지보수자의 안전 및 전철화에 따른 철도 관련 전기시스템의 보호를 위해 적합하게 처리되어야 한다. 따라서, 과전류 상태로 인한 귀선 전류 불평형과 시스템 유도 장애 및 고장을 방지하기 위해서는 귀선 전류의 정확한 분석이 필요하다. 또한, 귀선전류 고조파에 의해 오동작이 발생하면 열차 운행 중단 등의 문제가 발생될 수 있다. 본 논문에서는 이러한 귀선 전류 측정 및 분석 방법을 제시하고 고속열차 운행에 따른 호남고속철도 노선에서의 귀선전류 고조파 시험 결과를 제시하고 있다.

• 대한한방소아과학회지
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• 제17권2호
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• pp.199-211
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• 2003

저자는 경희대학교(慶熙大學校) 한의과대학(韓醫科大學) 부속한방(附屬韓方) 병원(病院)에 내원한 Guillain-Barre syndrome 환자를 한약(韓藥)과 간접염(間接炎) 및 침치료(鍼治療를) 사용하여 환자의 증상이 호전되었음을 확인하였으므로 이에 문헌고찰과 함께 보고하는 바이다.

• Journal of Biosystems Engineering
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• 제36권1호
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• pp.48-57
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• 2011

The computer vision system was designed and constructed to measure the weight of a dairy cattle. Its development involved the functions of image capture, image preprocessing, image algorithm, and control integrated into one program. The experiments were conducted with the model dairy cattle and the real dairy cattle by two ways. First experiment with the model dairy cattle was conducted by using the indoor vision experimental system, which was built to measure the model dairy cattle in the laboratory. Second experiment with real dairy cattle was conducted by using the outdoor vision experimental system, which was built for measuring 229 heads of cows in the cattle facilities. This vision system proved to a reliable system by conducting their performance test with 15 heads of real cow in the cattle facilities. Indirect weight measuring with four methods were conducted by using the image processing system, which was the same system for measuring of body parameters. Error value of transform equation using chest girth was 30%. This error was seen as the cause of accumulated error by manually measurement. So it was not appropriate to estimate cow weight by using the transform equation, which was calculated from pixel values of the chest girth. Measurement of cow weight by multiple regression equation from top and side view images has relatively less error value, 5%. When cow weight was measured indirectly by image surface area from the pixel of top and side view images, maximum error value was 11.7%. When measured cow weight by image volume, maximum error weight was 57 kg. Generally, weight error was within 30 kg but maximum error 10.7%. Volume transform method, out of 4 measuring weight methods, was minimum error weight 21.8 kg.

• 대한수의학회지
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• 제33권2호
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• pp.289-293
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• 1993

Following the death of more than 250 goats in one herd of 800 goats, imported from Australia, an epidemiological investigation was undertaken to determine the probable aetiology of this apprently mysterious disease. The syndrome was characterized by severe anemia(Hematocrit <20% ; normal range 24 to 48). All the affected animals were imported from Australia and all the motalities occurred during the period from September to November, 1992 Giemsa stain, acridine orange and indirect immunoflourescence tests were utilized in a survey involving 239 goats reared in Chonbuk Province. The positivity rates by acridine orange for anaplasmosis or piroplasmosis were 60.8% and 66.2% for imported and indigenous breeds respectively. It is tenatively concluded that the probable cause of death was anaplasmosis.

• The Korean Journal of Pain
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• 제28권1호
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• pp.4-10
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• 2015

Etifoxine (etafenoxine, $Stresam^{(R)}$) is a non-benzodiazepine anxiolytic with an anticonvulsant effect. It was developed in the 1960s for anxiety disorders and is currently being studied for its ability to promote peripheral nerve healing and to treat chemotherapy-induced pain. In addition to being mediated by $GABA_A{\alpha}2$ receptors like benzodiazepines, etifoxine appears to produce anxiolytic effects directly by binding to ${\beta}2$ or ${\beta}3$ subunits of the $GABA_A$ receptor complex. It also modulates $GABA_A$ receptors indirectly via stimulation of neurosteroid production after etifoxine binds to the 18 kDa translocator protein (TSPO) of the outer mitochondrial membrane in the central and peripheral nervous systems, previously known as the peripheral benzodiazepine receptor (PBR). Therefore, the effects of etifoxine are not completely reversed by the benzodiazepine antagonist flumazenil. Etifoxine is used for various emotional and bodily reactions followed by anxiety. It is contraindicated in situations such as shock, severely impaired liver or kidney function, and severe respiratory failure. The average dosage is 150 mg per day for no more than 12 weeks. The most common adverse effect is drowsiness at the initial stage. It does not usually cause any withdrawal syndromes. In conclusion, etifoxine shows less adverse effects of anterograde amnesia, sedation, impaired psychomotor performance, and withdrawal syndromes than those of benzodiazepines. It potentiates $GABA_A$ receptor-function by a direct allosteric effect and by an indirect mechanism involving the activation of TSPO. It seems promising that non-benzodiazepine anxiolytics including etifoxine will replenish shortcomings of benzodiazepines and selective serotonin reuptake inhibitors according to animated studies related to TSPO.

• 보건행정학회지
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• 제10권4호
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• pp.116-143
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• 2000

Considerable attention has been devoted in the accounting literature to identify the factors that cause or drive the costs of overhead activities. This paper extends recent cost driver research to the health care provider. In various case studies, it has been suggested that overhead costs are driven by volume and complexity variables. This paper investigates the significance of these variables in determining hospital overhead costs, how they are structurally related and how the cost impacts of these variables can be estimated in practice. This paper analyzes the determinants of hospital costs using the sample of South Korea hospitals for seven year during the period 1952－1997. The paper focuses on the extent to which hospital overhead costs depend on complexity, efficiency in addition to depending on more conventional volume based measures of hospital activity. The results of regression analysis suggest that volume and complexity factors positively and significantly affect overhead costs in the hospital industry. The results show that the complexity-related cost drivers strongly affected on the overhead costs in tile health care provider industry more than manufacturing industry which is mainly affected by volume-related cost drivers. That means each Industry may have different cost structures. Therefore it Is Important to find their proper cost structures and cost drivers and use them. Futhermore identification of overhead or indirect cost drivers is likely to be particularly useful in heath care. The identification of cost drivers can be of benefit to all health care stakeholders because these facilitates more efficient management of the national resources devoted to health care. While this study has documented that the level of service complexity is a significant determinant of hospital overhead costs, caution should be exercised in interpreting this as supportive of the cost accounting procedures associated with ABC. It is an open question whether even a well-designed ABC system will provide suitable proxies for marginal costs for decision making purposes.

• 디지털융복합연구
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• 제14권2호
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• pp.509-517
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• 2016

본 연구는 스포츠 계열 전공 대학생의 학업적 자기효능감, 결과기대 및 학과적응의 인과관계를 검증하는데 그 목적이 있다. 이러한 연구목적을 달성하기 위하여 스포츠 계열 전공 대학생 514명을 무작위추출 표집방법으로 추출하였으며 설문조사를 실시하여 분석하였다. 수집된 자료는 SPSS v18.0과 AMOSS v20.0을 이용하여 확인적요인북석, 상관관계분석, 경로분석을 실시한 결과는 다음과 같다. 학업적 자기효능감은 결과기대에, 학업적 자기효능감 및 이에 의한 결과기대는 학과적응에 통계적으로 유의한 영향을 미치는 것으로 나타났다. 학업적 자기효능감과 학과적응의 관계에서 결과기대의 간접효과도 통계적으로 유의한 영향을 미치는 것으로 나타났다. 이러한 결과로 스포츠 계열 전공 대학생의 학과적응을 높이기 위해 결과기대를 높이도록 하는 것이 중요하다고 사료된다.

• 디지털융복합연구
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• 제18권8호
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• pp.119-131
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• 2020

스타트업이 전통적 거대기업을 물리치는 역전현상의 원인으로, 기업가정신과 시장지향이 조직문화와 경영성과 관계에 미치는 매개효과를 살펴보는 것이 본 연구의 목적이다. Hayes(2013년)가 제안한 부트스트래핑의 연구방법을 통해 총효과, 직접효과, 간접효과 분석을 실시했다. 그 결과 조직문화와 경영성과 사이에는 직접적인 영향관계가 없었지만, 조직문화와 경영성과의 관계에서 기업가적 행동과 시장지향성을 모두 매개함으로써 경영성과에 긍정적인 영향을 미친다는 것을 확인했다. 본 연구는 기업가정신과 시장지향성 등 기존 이론과 연계하고 기업성과에 필요한 역량목표의 범위를 조직문화로 확대하였다는 점에서 의의가 있다. 기업은 경영성과와 가치창출을 위한 혁신지향적 조직문화를 창출하고 기업가적 행동과 시장지향성을 가지고 조직의 관성으로부터 문화를 개방할 필요가 있다.

• 한국건축시공학회지
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• 제10권1호
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• pp.137-145
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• 2010

석조 건조물의 역학적 성질은 일반적으로 석재 강도의 관점에서 설명된다. 강도를 측정하기 위해서 문화재의 훼손이 없는 초음파속도의 측정 방법이 이용되고 있다. 현재 시행되고 있는 초음파속도법은 표면거칠기, 석재 두께 등에 대한 보정을 실시하지 않고 있는 실정이다. 그리고 그리스와 같은 접촉재 사용으로 문화재의 표면에 오염이 발생할 수 있다. 따라서 본 연구에서는 석조 건조물의 강도를 간접법으로 추정하기 위하여 석재 표면거칠기, 석재두께, 접촉재의 종류, 초음파속도 측정방법 등을 주변수로 석재 간접법 강도 추정식을 제안한다. (1) 잔다듬 석재 초음파속도법에 의한 강도 추정식 : $f_{su}=19.1{\times}V_p+18.3(R^2=76.0)$ (2) 거친다듬 석재 초음파속도법에 의한 강도 추정식 : $f_{su}=7.9{\times}V_p+64.6(R^2=69.8)$.